Amoxiclav 375 mg yog qhov sib xyaw ua ke dav-tshuaj tiv thaiv kab mob antimicrobial. Nws ua tau zoo nyob rau hauv kev sib txuas nrog ntau yam kabmob sib kis, tau zoo los ntawm cov neeg mob feem ntau, tab sis yuav tsum muaj kev tsim nyog siv, yog li nws tsis tsim nyog rau kev siv tshuaj rau tus kheej.
ATX
Cov tshuaj no belongs rau cov tshuaj tua kabmob systemic nrog ATX code J01CR02.
Amoxiclav 375 mg yog qhov sib xyaw ua ke dav-tshuaj tiv thaiv kab mob antimicrobial.
Tso cov ntawv thiab cov nyob ua ke
Amoxiclav raug muag muaj li no:
- plab hnyuv taum coated ntsiav tshuaj;
- ntsiav tshuaj dispersible;
- hmoov rau kev tshem tawm hauv qhov ncauj;
- hmoov los ntawm ib qho kev daws teeb meem rau kev tswj kav dej yog npaj.
Kev nqis tes ntawm txhua yam tshuaj yog txiav txim siab los ntawm kev sib koom tes ua haujlwm ntawm 2 yam muaj txiaj ntsig - amoxicillin (semisynthetic penicillin) thiab clavulanic acid (ib qho tshuaj tiv thaiv ntawm qee yam kab mob enzymes).
Qhov ntau npaum ntawm 375 mg tsuas yog cov ntsiav tshuaj coated. Lawv muaj 250 mg ntawm amoxicillin nyob rau hauv trihydrate daim ntawv thiab 125 mg ntawm potassium clavulanate (2: 1 piv). Cov ntsiab lus ntxiv tau nthuav tawm:
- crospovidone;
- microcellulose;
- chaw muag tshuaj;
- magnesium stearate;
- colloidal silicon dioxide;
- croscarmellose sodium.
Qhov tshuaj ntawm 375 mg tsuas yog Amoxiclav ntsiav tshuaj hauv lub plhaub.
Cov pleev xim ua yeeb yaj kiab muaj talc, hypromellose, polysorbate, cellulose ethyl ester, triethyl citrate thiab titanium dioxide.
Cov ntsiav tshuaj tau ntim rau hauv lub hlwv los yog lub raj mis iav. Lawv muab tso rau hauv cov thawv ntawv tuab nrog cov lus qhia. Cov pob yuav muaj 15, 16, 20 lossis 21 ntsiav tshuaj.
Pharmacological kev txiav txim
Kev kho mob nyhuv ntawm cov tshuaj hauv cov lus nug yog muab los ntawm amoxicillin thiab clavulanate. Thawj zaug ntawm lawv yog cov tshuaj tua kab mob ib nrab los ntawm tus lej ntawm penicillins. Nws pom cov kab mob bactericidal. Lub tshuab ntawm kev txiav txim ntawm cov kab ke no yog qhov tsis kam hloov pauv ntawm kev ua si ntawm cov kab mob hloov ntshav. Cov enzymes yog qhov tsim nyog rau lub biosynthesis ntawm mucopeptide, uas yog lub hauv paus ntawm cov qauv ntawm cov kab mob ntawm phab ntsa. Raws li qhov tshwm sim, cov kab mob me me tuag taus.
Qhov ntau ntawm kev ua ntawm amoxicillin raug txwv, vim tias qee cov kab mob muaj peev xwm ua kom zais β-lactamases, uas rhuav tshem nws cov qauv. Clavulanate pab tiv thaiv kev ua tsis tau ntawm cov tshuaj tua kab mob. Nws khi cov z-lactamase enzymes, ua cov chaw ruaj khov kho chaw nyob ruaj khov nrog lawv.
Amoxiclav 375 pab tshem tawm txoj hnyuv thiab cov ntshav liab.
Qhov no tso cai rau koj los nthuav cov tshuaj antimicrobial ntawm amoxicillin thiab ua kom zoo tshem tawm ntau yam neeg sawv cev ntawm cov kab mob microflora pathogenic, suav nrog:
- plab hnyuv thiab hemophilic coli;
- streptococci;
- golden thiab pyogenic staphylococcus;
- coagulase-tsis zoo staphylococci;
- mob ntsws;
- Klebsiella;
- enterobacteria;
- clostridia;
- legionella;
- pob tsuas;
- Salmonella
- cov tshuaj tiv thaiv;
- Cuam Tshuam
- actinomycetes;
- Ntxaug Yaj
- daim ntawv teev npe;
- mob chlamydia
- treponema;
- vim li cas cov neeg ua mob hnoos qeev, mob taub hau, mob hlwb, txhaws qa, kab mob Lyme.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog nqus rau hauv lub plab zom mov. Qhov siab tshaj plaws ntawm nws cov khoom siv hauv cov ntshav tau txiav txim siab tom qab 60-90 feeb tom qab siv qhov ncauj. Bioavailability nruab nrab 70%. Koj tuaj yeem noj cov tshuaj tsis hais txog kev noj mov, tab sis nws zoo tshaj thaum pib noj mov.
Ob qhov tshuaj tau zoo tau muab faib rau hauv ntau cov qauv, tau pom nyob rau hauv cov khoom txaus hauv cov leeg, pob txha, cov rog rog, sib xyaw, alveoli, kabmob ntawm cov plab hnyuv rau hauv lub plab. Cov tshuaj tseem nkag mus rau hauv lub bile, bronchial secretion, purulent paug, zis, synovia, pleural effusion, peritoneal kua, intercellular yam khoom. Cov qe ntshav khi txog 25% clavulanate thiab kwv yees li 18% tshuaj tua kab mob.
Cov tshuaj no dhau lub txiaj ntsig thiab tawm hauv cov kua mis, tab sis cov ntshav-thaiv lub hlwb tseem ua tsis tau.
Kev ua ib feem ntawm amoxicillin, cov khoom siv tsis ua haujlwm. Txog li 70% yog tawm hauv nws cov qauv qub los ntawm lub raum tsim, 10-20% yog khiav tawm nrog quav. Ib nrab-lub neej yog 1-1.5 teev, nrog kev mob raum tsis ua hauj lwm - ntev txog 8,5 teev.
Clavulanate nquag ua haujlwm hauv lub siab. Qhov tseem ceeb tau faib tawm hauv cov zis, ib qho me me tawm hauv lub cev los ntawm lub qhov quav thiab lub tshuab ua pa. Qhov kev tshem tawm ib nrab-lub neej yog txog 1.5 teev, nrog kev ua haujlwm tsis zoo hauv lub raum, nce txog 4,5 teev.
Cov khoom xyaw nquag ntawm Amoxiclav 375 tuaj yeem raug muab tshem tawm uas siv cov txheej txheem hemodialysis.
Cov tshuaj yeeb dej caw tuaj yeem raug muab tshem tawm uas siv cov txheej txheem hemodialysis. Cov txiaj ntsig ntawm peritoneal lim ntshav tsis zoo.
Kev ntsuas rau siv
Cov tshuaj yog npaj rau kev kho mob ntawm cov kab mob sib kis los ntawm cov kab mob kis tau yooj yim rau nws txoj haujlwm. Cov lus qhia rau kev teem caij:
- Cov kab mob ntawm lub qhov ntswg, mob siab, qhov ncauj ntawm qhov ncauj thiab ntu, otitis media, mastoiditis.
- Pharyngitis, tonsillitis, pharyngeal abscesses.
- Mob ntsws o, mob legionellosis, hnoos txhaws qa, mob ntsws, haus luam yeeb ua pa, txhaws tsis taus pa.
- Kev kis mob ntawm cov mob tso zis (cystitis, pyelitis, nephritis, bacteriuria, urethral syndrome).
- Gynecological kab mob, prostatitis, gonorrhea, mob me chancre.
- Txoj hnyuv mob txhab, cholangitis, hepatic abscess, cholecystitis, pancreatic necrosis.
- Kev kis mob ntawm cov pob txha, pob qij txha txuas, sib xyaw thiab subcutaneous txheej, tom, tiv thaiv kev kis kab mob tom qab.
- Mob ntsws hnoos qeev
- Sepsis.
- Mixed kab mob.
Amoxiclav 375 yog siv los kho mob ntsws.
Cov Yuav Tsum Muaj
Amoxiclav tsis tuaj yeem siv yog tias muaj pes tsawg leeg tsis haum thiab yog tias muaj keeb kwm ua xua rau cov tshuaj tua kab mob,-lactam, suav nrog rau penicillin, carbapenem, kev npaj tshuaj cephalosporin. Lwm yam contraindications:
- tshuaj mob siab;
- cholestasis vim yog siv tshuaj tiv thaiv kab mob;
- mob ntsws lymphocytic;
- Tus kab mob Filatov;
- hnub nyoog txog 6 xyoo (rau daim ntawv no ntau npaum).
Nrog saib xyuas
Qhov yuav tsum tau ceev faj tshwj xeeb yog thaum muab tshuaj rau cov poj niam cev xeeb tub, cov niam tsev laus, cov neeg mob uas muaj lub raum thiab cov hlab ntsha tsis zoo, mob txhab rau lub plab, nrog rau kev siv tshuaj.
Yuav noj Amoxiclav 375 li cas
Nws raug nquahu kom tsis txhob muaj kev siv tshuaj txhaum cai. Nws lub sijhawm ntsib nws yuav tsum yog kws kho mob. Cov tshuaj yuav noj tsis tu ncua nrog dej txaus. Nws yog qhov zoo uas yuav noj nrog lawv nrog zaub mov, thaum pib noj mov. Qhov no yuav txo cov kev puas tsuaj rau txoj hnyuv, thaum tswj kev ua kom haum rau txoj kev pom zoo.
Cov tshuaj yuav noj tsis tu ncua nrog dej txaus.
Rau cov laus
Cov koob tshuaj yog txiav txim siab ntawm tus kheej. 375 mg ntsiav tshuaj yog npaj rau kev kho mob ntawm mob me. Lawv raug coj nrog tus ncua sij hawm 8 xuaj moos, nrog rau qhov mob txhab odontogenic, qhov luv ntawm cov koob tshuaj yog 12 teev. Yog hais tias muaj qhov ua haujlwm tsis zoo hauv lub raum thiab cov qib creatinine poob qis hauv qab 30, tom qab ntawd cov tshuaj raug coj mus 1-2 zaug hauv ib hnub. Thaum tsis muaj mob tso zis, lub sijhawm nruab nrab ntawm cov koob tshuaj tuaj yeem raug nce ntxiv txog 2 hnub lossis ntau dua.
Kev kho mob tsawg kawg nkaus yog 5 hnub. Nrog rau chav kawm ntev, tom qab 2 lub lis piam ntawm kev kho mob, nws yog ib qho tsim nyog yuav tau mus kuaj mob zaum ob. Tom qab tshem tawm txoj kev pom ntawm tus kab mob, cov ntsiav tshuaj yuav tsum tau noj tsawg kawg 48 teev.
Yuav muab Amoxiclav rau 375 cov menyuam li cas
Kev noj tshuaj rau menyuam yaus yog nce raws lub hnub nyoog thiab qhov hnyav ntawm tus menyuam. Txog 6 xyoo, nws raug nquahu kom muab cov menyuam yaus ncua ntawm cov tshuaj. Cov neeg mob lub hnub nyoog ntawm 12 xyoos raug muab tshuaj rau cov neeg laus noj yog tias lawv qhov hnyav tshaj 40 kg. Lub sijhawm ua haujlwm ntawm kev siv tshuaj tua kabmob yog txiav txim los ntawm tus kws khomob mus koom.
Noj cov tshuaj rau ntshav qab zib
Amoxiclav tuaj yeem raug kho rau cov neeg mob ntshav qab zib kom tiv thaiv ntau yam kev sib kis thiab mob. Nws tsis ua rau mob hyperglycemia, tab sis nws tuaj yeem muab pseudo-qhov tshuaj tiv thaiv zoo rau cov piam thaj thaum txheeb xyuas zis.
Amoxiclav tuaj yeem raug kho rau cov neeg mob ntshav qab zib kom tiv thaiv ntau yam kev sib kis thiab mob.
Sab sij huam
Yam tsis tsim nyog raug tshawb pom qhov tsis txaus ntseeg, feem ntau lawv thim rov qab. Qee tus ntawm lawv tuaj yeem tshwm sim qee lub sijhawm tom qab kawg ntawm kev kho mob.
Kev kho mob txoj hnyuv
Cov neeg mob tau txais cov lus tsis txaus siab txog xeev siab, tsis qab los noj mov, ntuav, mob plab, mob plab, mob plab hnyuv, tsaus nti ntawm tus nplaig thiab cov hniav. Tej zaum txoj kev loj hlob ntawm stomatitis lossis glossitis, mob plab, suav nrog pseudomembranous, cholestasis, mob siab rau hepatonecrosis, kev nce hauv kev ua haujlwm ntawm daim siab enzymes, dhia hauv bilirubin.
Hematopoietic plab hnyuv siab raum
Qee lub sij hawm muaj kev hloov pauv hauv cov xov tooj ntawm tes ntawm cov ntshav, c. suav nrog pancytopenia, lub sijhawm ua kom ntshav nce ntxiv.
Nruab nrab hauv lub paj hlwb
Feem ntau, mob taub hau, qaug zog, kiv taub hau tshwm. Qee lub sij hawm qhov kev xav tau ntawm lub siab tsis txaus siab, muaj lub suab siab tsis txaus ntseeg, ua kom tsaug zog, tsis meej pem, ua kom pom tseeb.
Noj cov tshuaj hauv nqe lus nug yuav ua rau kiv taub hau.
Los ntawm cov kab mob zis
Ntshav cov ntshav yuav pom nyob hauv cov zis. Crystalluria thiab tubulointerstitial nephritis yog ua tau.
Kev ua xua
Kev ua xua uas feem ntau ua rau mob urticaria (ua pob liab liab, liab ntawm kev sib txuam, o, khaus). Malignant erythema, necrotic tshwm sim, qhov zoo li ntawm kev mob hnyav, Quincke's edema, vasculitis, anaphylaxis tsis tshua muaj kev txhim kho.
Cov lus qhia tshwj xeeb
Thaum kho, lub xeev ntawm daim siab, lub raum, cov ntshav tsim ua haujlwm yuav tsum muaj kev tswj hwm.
Cov neeg mob uas muaj lub siab ntsws ua rau penicillins tuaj yeem ntsib kev ua xua nrog carbapenems thiab cephalosporins.
Thaum lub cev ua haujlwm tsis zoo, yuav tsum tau ua tshwj xeeb. Cov raum tsis ua haujlwm yuav tsum siv cov koob tshuaj me me thiab txo qis ntau zaus noj Amoxiclav. Txhawm rau tiv thaiv crystalluria, koj yuav tsum haus dej haus kom ntau thiab saib xyuas cov diuresis.
Raws li kev soj ntsuam, superinfection tuaj yeem txhim kho.
Yog tias ua rau lub siab ua haujlwm tsis zoo, yuav tsum tau saib xyuas tshwj xeeb thaum noj Amoxiclav.
Cawv tau zoo
Kev noj tshuaj tiv thaiv kab mob yog tsis sib xws nrog kev haus cawv los yog tshuaj siv nrog dej cawv ethyl hauv qhov muaj pes tsawg leeg.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Thaum tsav tsheb lossis kev ua haujlwm ua haujlwm xav tau kev ceev ntawm lub hlwb kev xav, yuav tsum ceev faj vim tias muaj peev xwm muaj ntau yam kev phiv los ntawm lub hauv nruab nrab lub paj hlwb.
Siv thaum cev xeeb tub thiab lactation
Cov poj niam cev xeeb tub tau muab tshuaj rau noj tsuas yog thaum muaj xwm txheej ceev, thaum muaj txiaj ntsig zoo rau tus neeg mob yuav muaj ntau dua qhov muaj peev xwm ua rau tus me nyuam hauv plab. Thaum pub niam mis rau lub sijhawm siv tshuaj tua kabmob, menyuam yuav tsum tsis pub mis los ntawm lub mis.
Noj ntau dhau
Yog tias cov tshuaj noj tau ntau dua, cov cim qhia txog kev lom tshwm sim (mob hauv plab, ntuav, raws plab). Cuam neeg, ua kom ntau dhau, pw tsis tsaug zog, ua rau tsis nco qab yuav ua rau pom kev.
Yog tias koj tshaj qhov noj tshuaj ntawm Amoxiclav, tsaus muag yuav tshwm sim.
Hauv thawj 4 teev tom qab kev tswj hwm qhov ncauj ntawm cov tshuaj, koj yuav tsum khoob lub plab thiab txo qhov kev nqus los ntawm kev noj Activated Carbon. Cov tsos mob kho mob yog kho raws, thiab lub cev qhuav dej yog tshem tawm yog tias tsim nyog. Tus neeg mob xav tau kev saib xyuas mob. Kev siv tshuaj ntau dhau yuav raug tshem tawm thaum mob hemodialysis.
Kev cuam tshuam nrog lwm yam tshuaj
Kev nqus cov feem cuam tshuam yog txhim kho los ntawm ascorbic acid thiab maj mam poob los ntawm glucosamine, antacids, aminoglycosides, thiab tshuaj laxatives. Cov ntsiab lus siv tshuaj tua kab mob nce ntxiv nrog rau kev sib txig cov tshuaj nrog phenylbutazone, allopurinol, diuretics, tshuaj tsis muaj tshuaj los tiv thaiv kev tiv thaiv, tubular zais pa blockers. Cov kev ua haujlwm pharmacological ntawm Amoxiclav tsawg dua thaum siv ua ke nrog Rifampicin, Chloramphenicol, tetracyclines, sulfonamides, macrolides.
Cov tshuaj nyob rau hauv nqe lus nug hauv kev sib xyaw nrog cov tshuaj anticoagulants txhim kho lawv cov hauj lwm zoo thiab qee qhov teeb meem ua rau muaj kev cuam tshuam thim rov qab lub sijhawm prothrombin, thiab nws txoj kev siv thaum sib luag nrog Ethinyl estradiol tuaj yeem ua rau kev mob ntshav rau uterine. Nws kuj tseem txo cov txiaj ntsig ntawm kev tiv thaiv qhov ncauj thiab txhim kho kev phiv ntxiv ntawm Allopurinol, Methotrexate, Disulfiram.
Amoxiclav txhim kho kev phiv tawm ntawm methotrexate.
Cov qauv ntawm Amoxiclav 375
Lwm cov tshuaj uas siv sib xyaw ntawm clavulanic acid nrog amoxicillin muaj cov nyhuv zoo sib xws:
- Augmentin.
- Panclave.
- Flemoklav Solyutab.
- Amoxicillin + Clavulanic acid.
- Medoclav.
- Amoxil.
- Novaklav.
- Amoxivan.
- Verklav.
- Amovicomb.
- Clamosar.
- Fibell.
- Foraclav.
- Lub Ecoclave.
- Bactoclav thiab lwm tus
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Hauv Latin, cov tshuaj hu ua Amoksiklav. Nws tsis yog muag dawb.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Cov tshuaj kws kho mob tau muab xa tawm.
Nqi
Tus nqi ntawm cov ntsiav tshuaj yog 250 mg + 125 mg - los ntawm 226 rubles. rau 15 pcs.
Cia li mob Amoxiclav 375
Tus sawv cev tshuaj txog kev lag luam yog tso kom deb ntawm cov menyuam yaus. Tso tshav ntuj thiab kub siab tshaj + 25 ° C yuav tsum tsis tso cai.
Hnub tas sij hawm
Cov ntsiav tshuaj tuaj yeem khaws cia rau 2 xyoos txij li lub sijhawm tsim khoom lag luam. Thaum kawg ntawm lub sijhawm tas sijhawm, lawv tsis tuaj yeem coj mus.
Cov yeeb yaj kiab ntawm Amoxiclav - cov tshuaj Augmentin siv tsis tau thaum kawg ntawm hnub tas sij hawm.
Amoxiclav tshuaj xyuas 375
Los ntawm cov kws kho mob thiab cov neeg mob, cov tshuaj tau txais ntau lub txiaj ntsig zoo.
Cov kws kho mob
Satimov K. G., kws kho hniav, Uryupinsk
Ib qho tshuaj tiv thaiv zoo tshaj plaws thiab nyab xeeb. Yog tias tsim nyog, muab tshuaj rau kuv cov neeg mob. Cov kev mob tshwm sim yog cov tsawg, tsis tshua muaj tshwm sim. Txhawm rau tiv thaiv lub plab, Kuv pom zoo kom noj nws nrog zaub mov, thiab probiotics xav tau los tswj cov hnyuv microflora.
Brovkina A.A., cov kws kho mob dav dav, Saratov
Ib qho tshuaj tua kab mob zoo uas ua haujlwm tau zoo hauv ntau pawg hnub nyoog. Nws zoo nyob hauv feem ntau. Ntawm qhov tshwm sim tsis zoo, cov pob khaus tawv nqaij thiab raws plab feem ntau tshwm sim.
Cov neeg mob
Alla, hnub nyoog 44 xyoo, Murmansk
Nws tau noj tshuaj tom qab lub puab tsaig raug mob thiab yuam kom rho tawm ntawm ntau cov hniav txhawm rau kom tus neeg ua kom paub tsis txhob tshwm sim. Cov tshuaj tsis muaj kev mob tshwm sim, thiab cov teeb meem tshwm sim tuaj yeem zam.
Elena, 37 xyoo, Rostov
Tshuaj tua kab mob zoo nyob ntawm tus nqi pheej yig. Kuv coj nws kom tshem tau ntawm qhov mob ntsws, tib lub sij hawm kuv haus ib tus neeg sawv cev probiotic. Kuv maj zoo siab. Thawj hnub, kuv lub taub hau mob, tab sis qhov no yuav tsis yog vim cov tshuaj, tab sis mus rau tus kab mob nws tus kheej. Kuv tsis pom lwm cov kev phiv tshuaj qhia nyob rau hauv cov lus qhia.
Gregory, 29 xyoo, Kostroma
Tus tub feem ntau yog neeg mob khaub thuas. Amoxiclav raug rho tawm rau nws rov ua haujlwm. Cov tshuaj pom tau zoo los ntawm cov menyuam tsis muaj zog lub cev thiab pabcuam kom rov zoo sai.
