Flemoklav Solutab yog daim ntawv tshiab soluble ntawm cov tshuaj tiv thaiv tshuaj tua kab mob. Kev sib xyaw ntawm amoxicillin nrog clavulanic acid yog tus txheej txheem kub hauv kev kho cov txheej txheem ntawm cov kab mob ntawm cov kab mob. Ntau qhov kev cuam tshuam tau muab los ntawm ob qho tseem ceeb tshuaj tua kab mob thiab the-lactamase inhibitor (clavulanate). Ua kom huv, raws li kev tshawb fawb tsis ntev los no, cov tshuaj ntawm cov tshuaj hauv cov pes tsawg leeg txo txoj kev pheej hmoo ntawm kev phiv.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Pab pawg npe: Amoxicillin + clavulanic acid
Ath
J01CR02 Amoxicillin xyaw nrog beta-lactamase inhibitor
Tso cov ntawv thiab cov nyob ua ke
Flemoklav Solutab 125 yog tsim los ua cov ntawv soluble rau kev tswj hwm qhov ncauj. Cov ntsiav tshuaj tuaj yeem nqos tau tag nrho lossis diluted hauv qhov dej tsawg. Qhov tsawg kawg ntawm cov tshuaj nquag tso cai rau siv cov khoom lag luam rau menyuam yaus.
Flemoklav Solutab yog daim ntawv tshiab soluble ntawm cov tshuaj tiv thaiv tshuaj tua kab mob.
Cov tshuaj muaj pes tsawg leeg ib soluble ntsiav tshuaj suav nrog cov tshuaj:
- amoxicillin (hauv daim ntawv ntawm trihydrate) - 145.7 mg, uas sib haum rau 125 mg ntawm ib qho tshuaj tua kab mob ntshiab;
- poov tshuaj clavulanate - 37.2 mg, uas nyob rau hauv cov nqe lus ntawm clavulanic acid yog 31.25 mg;
- kev nthuav dav: microcrystalline cellulose, emulsifier, crispovidone, vanilla, tsw, qab zib.
Cov tshuaj ntsiav tshuaj ntev ntev los ntawm xim dawb mus rau xim daj nrog rau xim av suav nrog, tsis muaj chamfers thiab notches, yog cim nrog "421" thiab lub logo ntawm cov tuam txhab.
Flemoklav muaj nyob rau hauv koob tshuaj 250, 500 thiab 875 mg (amoxicillin), uas yog xav txog ntawm cov tshuaj hauv cov lej 422, 424 thiab 425, feem.
Cov ntsiav tshuaj tawg yooj yim yog ntim hauv 4 pcs. hauv cov hlwv pob, 5 hlwv nyob hauv cov thawv ntawv thawv nrog cov lus qhia yuav tsum siv peev rau kev siv.
Pharmacological kev txiav txim
Los ntawm kev cuam tshuam nrog kev sib txuas ntawm cov kab mob phab ntsa, amoxicillin pab txhawb kev tuag ntawm pathogens. Muaj feem xyuam rau tus lej ntawm penicillins, thaum xub thawj nws muaj kev pom tseeb ntawm kev ua, thiab kev sib xyaw ua ke ua kom cov khoom siv tiv thaiv kev tiv thaiv thiab tiv thaiv kev tawm tsam ntawm cov kab mob tawv thaum kho.
Amoxicillin pom nyob rau niam mis.
Clavulanic acid tiv thaiv cov tshuaj tua kab mob los ntawm kev cuam tshuam ntawm beta-lactamases zais los ntawm qee cov kab mob thiab tuaj yeem tiv thaiv qhov cuam tshuam ntawm amoxicillin. Qhov no nthuav tawm lub spectrum ntawm cov tshuaj.
Flemoklav muaj txiaj ntsig tawm tsam aerobic thiab anaerobic microorganisms, suav nrog cov kab mob gram-negative thiab gram-zoo, nrog rau cov kab mob uas zais cov kev tiv thaiv enzymes - lactamases.
Cov Tshuaj Pharmacokinetics
Ob qho tshuaj yeeb dej caw yog cov muaj bioavailable: saum toj no 95% rau amoxicillin thiab kwv yees li 60% rau clavulanate. Kev tsis pom nyob rau hauv cov hnyuv tsis suav nrog tag nrho ntawm lub plab. Qhov siab tshaj plaws ntawm amoxicillin nyob rau hauv cov ntshav tau tiav hauv nruab nrab hauv 1-2 teev nrog kev tswj hwm ntawm qhov ncauj, uas ua ke nrog lub siab tshaj plaws qhov tseem ceeb ntawm clavulanic acid hauv ntshav.
Cov tshuaj tau dhau lub placental barrier. Amoxicillin pom muaj nyob hauv niam cov kua mis, rau clavulanate, tsis muaj cov ntaub ntawv no. Ob qho tshuaj yeeb tshuaj no muab tshuaj rau hauv lub siab, raug tshem tawm feem ntau los ntawm lub raum. Qhov nruab nrab ib nrab-lub neej yuav luag zoo ib yam thiab muaj txij li 1 txog 2 teev. Amoxicillin thiab clavulanate raug tawm thaum lub sij hawm hemodialysis.
Amoxicillin thiab clavulanate raug tawm thaum lub sij hawm hemodialysis.
Kev ntsuas rau siv
Cov tshuaj yog siv nrog cov pov thawj rhiab heev ntawm cov kab mob me me uas ua rau muaj tus kabmob, lossis ua rau tus neeg sawv cev dav dav rau kev kis tus kabmob. Kev ntsuas rau kev siv yog cov xwm txheej hauv qab no:
- kis kab mob ntawm cov pa ntawm sab saud thiab qis, nrog rau ENT kabmob hauv cov mob thiab mob sib kis;
- kev kis mob ntawm daim tawv nqaij thiab cov nqaij mos (nrog rau cov qhov txhab ua kom zoo nkauj, mob txhab, txhab);
- cov kab mob ua kom puas rau lub raum thiab mob txeeb zig (suav nrog cystitis, mob txhab zis, pyelonephritis).
Rau kev kho cov kab mob gynecological, nrog rau kev sib koom tes thiab mob pob txha, txhaj tshuaj ntau dua ntawm amoxicillin yog qhov yuav tsum tau ua. Yog li, cov tshuaj tuaj yeem raug xaj nyob rau hauv kev saib xyuas ntawm 500/125 lossis 875/125, siv daim foos tsim nyog ntsiav tshuaj.
Cov Yuav Tsum Muaj
Tsis txhob muab tshuaj rau cov tshuaj nrog intolerance rau ib yam khoom twg hauv cov muaj pes tsawg leeg thiab muaj cov tshuaj tiv thaiv kev qias neeg rau penicillins lossis cephalosporins hauv keeb kwm.
Lwm yam contraindications:
- kis mob mononucleosis;
- lymphocytic leukemia;
- cov tshuaj tua kab mob ntsig txog lub siab lossis tawv nqaij daj ntseg ua kom tsis muaj zog.
Nrog saib xyuas
Raws li kev saib xyuas kev kho mob tas li thiab rau cov cim nruj, kev kho yog ua raws li cov hauv qab no:
- daim siab ua haujlwm;
- mob raum tsis ua haujlwm;
- cov kab mob plab.
Flemoklav yog qhov kev ceeb toom yog tias, tom qab siv penicillins, txoj kev loj hlob ntawm colitis tau sau tseg.
Yuav ua li cas coj flemoklav solutab 125
Txoj kev daws teeb meem ntawm cov kev npaj ua nyuaj yog coj qhov ncauj tag nrho lossis hauv daim ntawv diluted. Txhawm rau npaj qhov kev ncua, tsawg kawg 30 ml ntawm dej yuav tsum, qhov siab tshaj ntawm cov kua yog ib nrab ib khob. Cov ntsiav tshuaj yog yoog kom txog thaum yaj tag thiab muaj pes tsawg leeg yog qaug cawv tom qab npaj.
Cov tshuaj tua kab mob tsis yog sau rau tshuaj tua kab mob siab-cuam tshuam rau cov nplooj siab ua haujlwm thiab nws lwm yam kab mob.
Pes tsawg hnub haus
Lub sijhawm ntawm kev kho yog txiav txim los ntawm tus kws kho mob raws li kev mob hnyav ntawm tus neeg mob lub sijhawm, hnub nyoog, lub cev nyhav, cov kabmob sib kis thiab qhov kis ntawm tus kabmob. Qhov nruab nrab chav kawm kav tsawg kawg 5 hnub thiab tuaj yeem ncua ntev txog 7-10 hnub. Cov tshuaj tsis tau sau tseg rau lub sijhawm ntau dua 14 hnub.
Ua ntej lossis tom qab noj mov
Qhov ua tau zoo ntawm txhua feem ntawm cov tshuaj yog ywj pheej ntawm cov zaub mov noj. Txhawm rau tiv thaiv kev phiv los ntawm txoj hnyuv hauv plab, nws raug nquahu kom haus ib ntsiav tshuaj nrog zaub mov.
Puas yuav mob ntshav qab zib?
Cov tshuaj tsis muaj cov tshuaj sib kis hauv cov ntshav qab zib mellitus thiab raug pom zoo rau kev siv tom qab sab laj nrog koj tus kws kho mob.
Sab sij huam
Ua tsaug rau cov tshuaj sib xyaw ua ke thiab cov tshuaj kho kom haum, cov tshuaj tau zam ntau dua li nws cov yeeb yaj kiab hauv pawg neeg penicillin. Qhov xwm txheej ntawm qhov tshwm sim tsis zoo yog 60% tsawg dua qhov ntawm amoxicillin. Yog tias cov koob tshuaj uas kws kho mob tau sau tseg yuav pom, qhov xwm txheej tsis zoo yuav tsis tshua muaj tshwm sim.
Cov tshuaj tsis muaj cov tshuaj sib kis hauv cov ntshav qab zib mellitus thiab raug pom zoo rau kev siv tom qab sab laj nrog koj tus kws kho mob.
Cov kab mob superinfection, cov kab mob fungal tuaj yeem ua tau raws li kev phiv tsuas yog los ntawm cov koob tshuaj ntau ntawm cov tshuaj siv hauv cov kev kawm ntev.
Kev kho mob txoj hnyuv
Los ntawm lub plab zom mov, qhov tshwm sim ntawm xeev siab, ntuav, mob plab yog tau. Nrog kev kho mob ntev, cem quav, thim rov qab ua rau lub siab ua haujlwm yog ua tau, nyob rau hauv tus neeg mob cais, cov tsos mob pseudomembranous mob plab (mob raws plab tsis tu ncua) tau sau tseg.
Kev hloov pauv ntawm cov kev ua ntawm transaminases, kev nce bilirubin feem ntau tsis tshwm sim hauv cov poj niam thiab menyuam yaus. Xws li cov tshuaj rau yeeb tshuaj yog cov yam ntxwv ntawm tus txiv neej, tshwj xeeb tshaj yog tom qab 65 xyoo. Kev pheej hmoo ntawm kev mob hepatic nce nrog cov chav kawm ntev: ntau dua 2 lub lis piam.
Kev phiv tshuaj los ntawm lub plab zom mov tuaj yeem tshwm sim rau hnub 4 ntawm kev noj tshuaj, tam sim ntawd tom qab kho lossis tom qab ob peb lim piam. Kev hloov pauv yog qhov rov ua tau.
Hematopoietic plab hnyuv siab raum
Los ntawm cov lymphatic thiab hematopoietic systems, kev ntshawv siab yog sau tseg tsis qhia. Lub sijhawm ntev ntawm prothrombin lub sijhawm yog ib ntus. Qee lub sijhawm xws li kev hloov pauv raug pom:
- leukopenia;
- thrombocytopenia;
- granulocytopenia;
- pancytopenia;
- anemia
Kev hloov pauv ntawm cov ntshav cov ntshav yog qhov thim rov qab, thiab tom qab ua tiav ntawm kev kho lossis tshem tawm cov tshuaj, cov ntsuas tau rov qab los ntawm lawv tus kheej.
Nruab nrab hauv lub paj hlwb
Kev kho mob Amoxicillin / clavulanic acid tuaj yeem nrog kev mob taub hau. Kiv taub hau, kiv, feem ntau tshwm sim raws li cov cim qhia ntawm kev haus ntau dhau. Cov tsos mob ntawm cov tsos mob neurological feem ntau tsis tshua sau tseg: ntxhov siab, pw tsaug zog, hyperactivity lossis nruj.
Los ntawm cov kab mob zis
Kev tsis xis nyob uas tshwm sim hauv qee qhov mob tsawg (khaus, kub nyhiab, tawm hauv dej) qhia kev ua txhaum nyob hauv microflora qhov chaw mos. Hauv cov xwm txheej cais, kev loj hlob ntawm candidomycosis, interstitial nephritis raug sau tseg.
Kev ua xua
Cov tsos mob ntawm daim tawv nqaij ua pob ua pob thaum pib ntawm chav kawm yuav qhia tau qhov tsis txaus ntseeg rau lub Cheebtsam. Tsis tshua muaj, cov tshuaj provokes ntau hom dermatitis, erythema, Steven-Johnson syndrome, ua xua vasculitis. Qhov tsis txaus ntseeg loj npaum li cas yog nyob ntawm kev txhaj tshuaj ntawm cov tshuaj tua kab mob thiab qhov mob ntawm lub cev. Hauv cov xwm txheej nyhav, kev txhim kho ntawm edema thiab anaphylactic kev poob siab.
Cov lus qhia tshwj xeeb
Cawv tau zoo
Kev siv cov tshuaj tua kab mob tsim kev tsim txom ntxiv rau daim siab thiab lub raum. Kev siv dej cawv ib txhij ua rau lub cev ua rau lub cev puas lom ntxiv ntau zaus. Feem ntau, qhov kev hloov pauv ceev ceev hauv lub siab, tachycardia, kub xaim, ntuav, thiab ntuav yog pom.
Kev siv dej cawv ib txhij ua rau lub cev ua rau lub cev puas lom ntxiv ntau zaus.
Cawv thiab amoxicillin yog antagonists. Ib qho mob tshwm sim los ntawm lawv cov kev sib cuam tshuam tuaj yeem cuam tshuam tau lub neej.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Amoxicillin thiab clavulanate tsis cuam tshuam rau qhov tshuaj tiv thaiv tus nqi thiab kev muaj peev xwm los tswj cov txheej txheem nyuaj. Kev xyuam xim yuav tsum tau coj thaum tsav tsheb thaum lub caij kho rau cov neeg uas tau noj tshuaj rau thawj zaug thiab kev tiv thaiv ib leeg ntawm lub cev tsis tau saib xyuas.
Siv thaum cev xeeb tub thiab lactation
Tsis muaj pov thawj tshawb fawb txog kev mob tshwm sim ntawm tus me nyuam hauv plab thaum Flemoclav raug tshuaj rau cov poj niam cev xeeb tub. Nws pom zoo kom tsis txhob siv tshuaj tua kab mob hauv thawj peb lub hlis. Hauv qhov thib 2 thiab thib 3 txiav tawm, cov tshuaj tau tawm tom qab ntsuas qhov txiaj ntsig-raug mob nyob rau hauv kev saib xyuas tas li.
Kev noj cov tshuaj amoxicillin hauv niam cov kua mis tuaj yeem ua rau muaj kev tawm tsam ua xua, raws plab, lossis mob plab hnyuv rau cov menyuam mos. Hauv qhov no, kev pub niam mis rau menyuam kom nres kom txog rau thaum kawg ntawm kev kho.
Yuav ua li cas muab flemoklava solutab rau 125 tus menyuam
Ib qho tshuaj me me ntawm amoxicillin thiab clavulanate hauv tshuaj (soluble form) tso cai rau nws siv los kho cov menyuam yaus. Cov koob tshuaj txhua hnub yog teem los ntawm tus kws kho mob nyob ntawm qhov mob hnyav ntawm tus mob thiab lub cev qhov hnyav. Txij li 1 txog 30 mg ntawm amoxicillin noj rau 1 kg ntawm qhov hnyav, qhov tau xam cov tshuaj ntawm lub hnub nyoog.
Thaum muaj mob hnyav, tus kws kho mob tuaj yeem siv tshuaj ntxiv rau ob npaug. Qhov siab tshaj plaws niaj hnub rau cov menyuam yaus yog 15 mg ntawm clavulanate thiab 60 mg ntawm amoxicillin rau 1 kg ntawm lub cev hnyav. Tsuas yog tom qab muaj hnub nyoog 12 xyoos lossis hnyav dua 40 kg nws raug tso cai muab tshuaj rau cov neeg laus cov yeeb tshuaj.
Dosage hauv lub hnub nyoog laus
Cov tshuaj sib xyaw ua ke tau txais zoo los ntawm cov neeg laus laus. Koob tshuaj yuav tau kho tsuas yog muaj teeb meem lub raum tsis txaus.
Daim ntawv thov rau lub raum khiav tsis zoo
Kev kho ntawm cov koob tshuaj amoxicillin ua ke nrog clavulanic acid nyob rau hauv lub raum pathologies yog qhov tsim nyog vim muaj kev maj mam ua tiav ntawm cov tshuaj. Ua raws li cov neeg lub raum tsis ua haujlwm, ib koob tshuaj ib zaug tuaj yeem txo, thiab lub sijhawm nruab nrab ntawm cov ntsiav tshuaj yuav raug nce ntxiv.
Kev kho yuav tsum tau ua los ntawm tus kws kho mob hlwb (nephrologist) raws li qhov kev ntsuas ntawm glomerular pom npaum li cas. Txo cov khoom noj txhua hnub pib yog tias creatine tshem tawm kev nyeem poob qis dua 30 ml / min.
Siv rau lub siab ua haujlwm tsis zoo
Cov tshuaj tiv thaiv kab mob yuav tsum tau txais kev ceeb toom nrog ceev faj hauv cov neeg mob uas lub siab ua tsis tau zoo. Txoj kev kho yog ua tau nrog kev soj ntsuam tas li ntawm ntsuas.
Kev kho ntawm cov koob tshuaj amoxicillin ua ke nrog clavulanic acid nyob rau hauv lub raum pathologies yog qhov tsim nyog vim muaj kev maj mam ua tiav ntawm cov tshuaj.
Noj ntau dhau
Thawj cov tsos mob ntawm kev haus ib ce tuaj yeem yuam kev vim phiv los ntawm cov tshuaj. Xeev siab, ntuav, raws plab yog nrog dej hauv lub cev. Yog tias pom muaj cov txiaj ntsig tshwm sim, koj yuav tsum tau sab laj nrog kws kho mob.
Kev kho mob rau kev siv ntau tshaj muaj nyob rau hauv kev noj cov sorbents, rov ua cov dej-electrolyte sib npaug; nrog kev tshem tawm, Diazepam yog kev tso cai. Hauv cov mob hnyav, kev kho mob hemodialysis yog tus kho.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev tswj fwm ntawm Flemoclav nrog glucosamine, laxatives thiab antacids, kev nqus ntawm cov tshuaj tua kab mob hauv lub plab zom mov qis; nrog vitamin C - nrawm.
Lwm cov kev sib cuam tshuam tau kawm:
- Nrog tshuaj tua kab mob ntawm cov kab mob bactericidal: aminoglycosides, cephalosporins, rifampicin, vancomycin thiab cycloserine - qhov kev sib nrig ntxiv hauv kev ua tau zoo.
- Nrog rau cov tshuaj bacteriostatic: tetracyclines, sulfonamides, macrolides, lincosamides, chloramphenicol - antagonism.
- Nrog indirect anticoagulants txhim kho lawv cov nyhuv. Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam kev ntshav coagulation tsis tu ncua.
- Nrog rau qee qhov ncauj tiv thaiv tsis tau, lawv cov hauj lwm zoo txo. Ua rau muaj feem los ntshav ntau ntxiv.
- Tubular secretion blockers (NSAIDs, phenylbutazone, diuretics, thiab lwm yam) nce qhov kev tso tawm ntawm amoxicillin.
Kev kho mob rau kev siv ntau tshaj muaj nyob hauv kev noj cov thuv.
Nws tsis pom zoo kom sau ntawv rau tib lub sijhawm Flemoklav, Disulfiram, Allopurinol, Digoxin, uas cuam tshuam nrog Amoxicillin.
Analogs
Txhais cov ntsiab khoom tseem ceeb:
- Flemoxin Solutab;
- Amoxicillin;
- Augmentin;
- Amoxiclav;
- Lub Ecoclave;
- Panclave.
Cov tshuaj analogues ntawm cov tshuaj yuav muaj clavulanic acid los yog tsuas yog amoxicillin. Thaum hloov cov tshuaj, them sai sai rau cov lus sib xyaw thiab ntau npaum li cas ntawm txhua feem.
Nyiaj so koobtsheej tej yam kev mob flemoklava solyutab 125 los ntawm cov chaw muag tshuaj
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Cov tshuaj tua kab mob hais txog cov tshuaj uas kws kho mob sau tseg. Feem ntau ntawm cov chaw muag tshuaj yuav kom teem sijhawm kws kho mob rau qhov muag nws.
Nqi
Tus nqi ntawm Flemoklav Solutab hauv ib qhov tshuaj ntau npaum li 125 / 31.25 mg yog nyob rau ntau qhov chaw muag tshuaj ntawm 350 txog 470 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cia qhov kub thiab txias - tsis siab tshaj + 25 ° C. Khaws tsis ncav cuag ntawm cov menyuam yaus.
Hnub tas sij hawm
Txheeb rau qhov kom nruj ntawm lub pob, cov tshuaj tau khaws nws lub zog rau 3 xyoos.
Chaw tsim tshuaj paus flemoklava solutab 125
Astellas Pharma Europe, Leiden, Netherlands
Txheeb xyuas flemoklava solutab 125
Alina, 25 xyoo, Petrozavodsk:
Flemoklav soluble taw pediatrician. Lawv nyuam qhuav pib mus kawm ntawv kindergarten thiab muaj mob tsis tu ncua.Thaum mob ntsws pib, tus kws kho mob tau sau tshuaj tua kabmob. Tus mob zoo dua tom qab 5 hnub ntawm kev kho mob. Txawm hais tias nws yeej ntshai me ntsis, tsis muaj kev cuam tshuam. Thaum yaj tag, nws yuav yooj yim dua rau lawv haus dej, txawm tias lub saj tseem tsis txaus siab, tab sis tus tub flatly tsis kam muab tshuaj rau haus.
Marina, 35 xyoo, Omsk:
Tom qab mob npaws, tus tub (7 xyoo) pib mob pob ntseg thiab qhov kub tau dhia ob peb hnub. ENT txheeb xyuas sab laug otitis media thiab sau ntawv Flemoklav Solutab thiab Otipax tawm hauv pob ntseg. Cov tshuaj tua kab mob tsis yog pheej yig, tab sis nws pab sai sai. Tom qab ob lub tshuaj noj, nws twb tsaug zog zoo. Otitis kho zoo hauv ib lub lis piam.
