Insulin Lantus thiab nws cov khoom sib txig sib luag

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Cov tshuaj insulin glargine yog ib qho piv txwv ntawm tib neeg pancreatic hormone, uas tau los ntawm kev rov ua kom tiav cov kab mob DNA ntawm qee yam.

Nws yog tus cwj pwm los ntawm kev solubility tsawg kawg nkaus hauv qhov chaw nruab nrab. Cov tshuaj no yog qhov tseem ceeb ntawm cov tshuaj hu ua Lantus.

Cov tshuaj no muaj cov nyhuv hypoglycemic uas muaj zog thiab siv los tswj cov metabolism hauv qabzib. Cov lus hauv qab no muaj cov lus qhia tag nrho txog cov tshuaj Lantus, cov kab mob analogues ntawm kuj tuaj yeem nrhiav tau ntawm no.

Qhia txog ntawm cov tshuaj

Nws yog siv thaum tus neeg mob muaj ntshav qab zib mellitus, uas yuav tsum tau kho mob nrog insulin. Tshwj xeeb feem ntau, cov tshuaj raug tawm rau cov laus, cov hluas thiab menyuam yaus hnub nyoog ob xyoos. Tus neeg sawv cev hypoglycemic nws tus kheej muaj cov tsos ntawm cov kua ntshiab thiab tsis muaj zog.

Cov tshuaj insulin

Tom qab nws tau qhia nyob rau hauv daim tawv nqaij, qhov ua kua qaub ntawm cov tshuaj tiv thaiv yog ua kom tiav, uas ua rau cov tsos ntawm microprecipitate, los ntawm qhov tsawg kawg ntawm ntu ntawm insulin glargine tso tawm tsis tu ncua. Cov tshuaj nquag hloov pauv mus rau ob qhov kev siv tshuaj tiv thaiv metabolites M1 thiab M2.

Thaum lub caij, cov hauj lwm siab ntawm cov tshuaj no tau raug pov thawj. Hauv cov menyuam mos uas muaj ob xyoos rov hauv uas muaj ntshav qab zib hom 1, txhua yam kev noj qab haus huv zoo dua qub tom qab kev tswj hwm.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias hauv cov menyuam yaus txij li ob mus txog rau 6 xyoo, qhov muaj feem yuav ua rau muaj ntshav siab nrog cov lus qhia tau tseeb thaum siv cov tshuaj muaj qis dua, ob leeg thoob plaws ib hnub thiab hmo ntuj hauv kev sib piv nrog lwm yam tshuaj uas muaj qhov zoo sib xws.

Cov Yuav Tsum Muaj

Cov tshuaj tsis pom zoo rau kev siv nrog:

  • siab rhiab heev rau kev nquag ntawm cov tshuaj;
  • cov menyuam yaus hnub nyoog qis dua ob xyoos;
  • nrog kev ceev faj rau cov poj niam hauv txhua theem ntawm cev xeeb tub.

Sab sij huam

Ib qho ntxim nyiam tshaj plaws ntawm kev siv tshuaj yeeb yog hypoglycemia.

Nws sawv cev rau lub cev feem ntau tshwm sim los rau kev kho mob insulin. Qhov no ua tau rau hauv qhov xwm txheej twg cov koob tshuaj no yog ntau heev hauv kev sib piv nrog cov kev xav tau ntawm lub cev.

Cov tsos mob ntawm tus kab mob no tshwm sim tam sim ntawd. Tab sis, feem ntau neuropsychiatric cuam tshuam tiv thaiv keeb kwm ntawm neuroglycopenia yog ua ntej los ntawm cov cim ntawm adrenergic counterregulation.

Yuav nkag li cas?

Cov tshuaj no yog cim rau lub caij nyoog ntawm kev sib kis, yog li ntawd, nws yog qhov zoo dua rau xaiv nws dua li, piv txwv li, lwm cov tshuaj Lantus insulin analogues. Nws yog tshuaj rau cov neeg mob uas muaj ntshav qab zib insulin, thiab hauv qhov no peb tab tom hais tsis yog tsuas yog hais txog thawj hom mob.

Feem ntau cov feem ntau hloov pauv cov tshuaj insulin Lantus yog Novorapid, Humalog, thiab Apidra.

Lantus, zoo li qee yam duab ntawm cov tshuaj insulin no, yog tswj los ntawm kev txhaj tshuaj subcutaneous. Nws tsis yog npaj rau kev tswj hwm tshuaj.Tsoov nco ntsoov, lub sijhawm ua haujlwm ntawm cov tshuaj no tsuas yog sau tseg thaum nws qhia rau hauv cov roj ntsha subcutaneous.

Yog tias koj tsis quav ntsej txoj cai no thiab qhia nws ua ntu kawg, koj tuaj yeem ua rau muaj qhov tshwm sim ntawm kev mob ntshav qab zib siab heev. Nws yuav tsum nkag mus rau hauv cov roj txheej ntawm lub plab, xub pwg lossis pob tw.Nws yog ib qho tseem ceeb kom tsis txhob hnov ​​qab tias koj tsis tuaj yeem hno qhov kev txhaj tshuaj ntawm qhov insulin hauv qhov qub, vim qhov no yog fraught nrog kev tsim cov hematomas.

Lantus 'analogues, zoo li nws tus kheej, tsis yog kev ncua, tab sis kev daws teeb meem kom meej.

Nws yog ib qho tseem ceeb kom sab laj nrog koj tus kws kho mob txog kev siv tsis yog cov tshuaj nws tus kheej, tab sis nws cov analogues nrov, uas muaj cov txiaj ntsig zoo ib yam.

Qhov pib ntawm kev ua ntawm Lantus thiab qee qhov ntawm nws cov analogues tau pom raws nraim ib teev tom qab, thiab nruab nrab lub sijhawm ntev ntawm kwv yees li ib hnub. Tab sis, qee zaum nws tuaj yeem ua kom ntev kawg rau nees nkaum cuaj teev, nyob ntawm qhov muab ntau npaum li cas - qhov no tso cai rau koj tsis nco qab txog kev txhaj tshuaj rau tag nrho ib hnub.

Analogs

Txhawm rau kom tshem tawm cov kev tsis zoo tshwm sim ntawm cov ntshav qab zib, cov kws tshaj lij tau sau tseg rau cov tshuaj Lantus thiab nws cov analogues nrov. Ntev mus ntev heev, cov tshuaj yeeb tshuaj no tau maj mam paub thiab tam sim no lawv suav tias yog tus naj npawb ib hauv kev tawm tsam qhov kev ua txhaum ntawm endocrine system.

Ntau cov txiaj ntsig ntawm cov tshuaj tua kabmob pancreatic:

  1. nws yog qhov ua tau zoo thiab muaj peev xwm txo cov kev sim ntshav qab zib;
  2. muaj ib qho zoo tshaj plaws kev ruaj ntseg profile;
  3. yooj yim mus siv;
  4. koj tuaj yeem synchronize kev txhaj tshuaj ntawm cov tshuaj nrog nws tus kheej zais cia ntawm qhov hormone.

Analogues ntawm cov tshuaj no hloov lub sijhawm ntawm tib neeg kev cuam tshuam ntawm tib neeg ntawm lub cev ua kab mob rau cov neeg mob ua kom tus tib neeg lub cev muaj zog rau kev kho mob thiab qhov kev nplij siab tshaj plaws rau tus neeg mob uas ua rau mob endocrine.

Cov tshuaj no pab ua kom tiav ntawm kev pheej hmoo ntawm kev poob hauv cov ntshav qab zib thiab ua tiav cov hom phiaj glycemic.

Cov tshuaj Humalog

Nyob rau lub sijhawm no, muaj ob peb qho ntawm cov khoom siv tsis haum ntawm tib neeg pancreatic hormone:

  • ua vauv (Humalog, Apidra, Novorapid Penfill);
  • Lub caij nyoog (Lantus, Levemir Penfill).

Cov tshuaj ntev heev ntawm Lantus Solostar analogues, nyob rau hauv lem, kuj muaj - Treciba yog suav tias yog ib qho ntawm nto moo tshaj plaws.

Lantus lossis Tresiba: qhov twg zoo dua?

Yuav pib nrog, koj yuav tsum xav txog txhua tus ntawm lawv tus kheej. Cov tshuaj nquag siv ntawm cov tshuaj hu ua Tresiba yog insulin degludec. Zoo li Lantus, nws yog ib qho piv txwv ntawm tib neeg pancreatic hormone. Ua tsaug rau kev mob siab ua haujlwm ntawm cov kws tshawb fawb, cov tshuaj no tau txais cov khoom tshwj xeeb.

Los tsim nws, tshwj xeeb biotechnologies ntawm recombinant DNA tau siv nrog kev koom tes ntawm Saccharomyces cerevisiae lim, thiab cov qauv molecular ntawm tib neeg insulin tau hloov kho.

Tresiba tshuaj

Lub sijhawm tam sim no, cov tshuaj no tuaj yeem siv los ntawm cov neeg mob, ob hom mob ntshav qab zib thawj thiab thib ob.

Raws li cov lus cog tseg ntawm cov tuam ntxhab, tsis muaj ntshav qab zib yuav tsum tshwm sim thaum siv tshuaj Tresiba.Muaj lwm qhov zoo ntawm cov tshuaj: tsawg dua hloov pauv nyob rau theem ntawm glycemia thaum nruab hnub. Hauv lwm lo lus, thaum kho kev kho mob siv cov tshuaj Treciba, cov ntshav qab zib kom siab yog tswj nyob rau nees nkaum plaub teev.

Qhov no yog qhov txiaj ntsig tseem ceeb, vim tias kev siv cov kab xev ntawm Lantus no tso cai rau koj tsis xav txog cov tshuaj insulin tsis yog nruab hnub, tabsis thaum tsaus ntuj.

Tab sis cov cuab yeej no muaj ib qho teeb meem tseem ceeb: nws tsis pom zoo rau kev siv los ntawm cov neeg muaj hnub nyoog kaum yim xyoo, cev xeeb tub thiab poj niam. Nws kuj tseem tsis tuaj yeem raug xa mus los ntawm kev txhaj tshuaj rau ntshav. Tsuas yog tso cai siv tau subcutaneous xwb.

Raws li rau Lantus, tag nrho nws cov kev zoo tau piav qhia saum toj no. Tab sis yog tias peb kos cov kab sib luag ntawm cov tshuaj insulin hloov pauv no, peb tuaj yeem xaus tias qib ntawm glycated hemoglobin txo qis kom ntau dua nrog kev siv Tresib tshuaj dua li siv nrog Lantus. Tias yog vim li cas analogues ntawm tom kawg ua ntau yam dua.

Txij li, hmoov tsis zoo, Lantus tau txiav tawm, nws yog qhov zoo rau cov neeg mob ntawm endocrinologist uas raug kev txom nyem los ntawm ob hom ntshav qab zib coj tus tshuaj insulin hloov hu ua Tresiba.

Lantus analogues hauv Russia

Lub sijhawm tam sim no, hauv peb lub teb chaws feem ntau nrov tshaj plaws ntawm cov khoom neeg hloov kho rau tib neeg cov kua dej yog Tresiba thiab Detemir (Levemir).

Cov tshuaj Levemir

Txij li thaum cov ntsiab lus zoo ntawm Tresiba tau piav qhia saum toj no, ob peb lo lus yuav tsum tau hais txog Levemir. Nws suav hais tias yog qhov tseem ceeb tshaj plaws hu ua kev tsis sib txuas ntawm tib neeg cov kua dej ntawm kev ua haujlwm ntev, uas tau tswj hwm ib zaug lossis ob zaug ib hnub.

Lub sijhawm no, Levmir tau siv los pib kho insulin rau hom ntshav qab zib hom 2. Nws muaj peev xwm los muab thiab tswj hwm kom txaus cov tshuaj insulin hauv cov ntshav. Qhov no tso cai rau koj los tswj glycemia.Ntawm qhov zoo ntawm cov roj ntsha no yog qhov nws tau lees tias yuav muaj cov ntshav qabzib tsawg nyob hauv tib neeg.

Tsis tas li ntawd, hais txog nws cov txiaj ntsig zoo thaum hmo ntuj, hauv kev sib piv nrog lwm cov tshuaj, nws tso cai rau koj xaiv ntau dua cov tshuaj kom ua tiav qhov xav tau ntshav qab zib kom ntau. Ib qho ntxiv, nws tsis ua rau kev hnyav tshaj qhov ntxiv ntawm qhov phaus.

Raws li rau lub sijhawm ntawm kev kho mob, nws nyob ntawm lub koob tshuaj. Ua ntej, koj yuav tsum siv Levemir ib zaug ib hnub. Thawj koob tshuaj rau cov neeg mob uas tsis tau txhaj tshuaj insulin yav tas los yog kwv yees li 9 units lossis 0.1-0.2 units / kg nrog lub cev hnyav.

Raws li koj paub, glargini insulin thiab Lantus yog ib qho thiab tib qho, vim tias thawj cov tshuaj tiv thaiv yog cov tshuaj nquag ntawm cov tshuaj thib ob. Nws yog ntawv tawm tsuas yog los ntawm tus kws kho mob mus koom, yog li kev ywj siab siv cov tshuaj insulin no raug txwv.

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Cov chaw tsim khoom ntawm Lantus tsis nyob hauv ib lub tebchaws, tab sis ob - Lub Tebchaws Yelemees thiab Russia. Nws tuaj yeem muas tau ntawm qee lub tsev muag tshuaj, tab sis tsis ntev los no nws cov tshuaj noj lossis cov nquag ua haujlwm nws tus kheej tau siv ntau dua. Qhov no vim tias cov tshuaj tau nyuam qhuav tau txais kev cuam tshuam nyuaj heev. Hauv Lantus, cov ntawv qhia Latin feem ntau zoo li qhov no: “Lantus 100 ME / ml - 10 ml”.

Txoj kev kho mob hnyav siv cov tshuaj no tuaj yeem txhim kho txoj kev noj qab haus huv thiab tswj tau glycemia hauv cov tib neeg muaj ob hom ntshav qab zib. Nws yog ib qho tseem ceeb uas yuav tau ua tib zoo ua ntej txais tos kom tsis txhob muaj kev phiv tshuaj. Nco ntsoov ua raws nraim li ntau npaum li cas los ntawm tus kws kho mob kom tiv thaiv ntau yam teeb meem thiab qhov tshwm sim ntawm kev siv.

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