Noliprel yog cov tshuaj niaj hnub ua ke los txo cov ntshav siab. Ob lub cev sib xyaw ua ke hauv ib ntsiav tshuaj tag nrho ua tau raws li qhov xav tau ntawm txoj kev tshiab rau kev kho mob ntshav siab. Cov tshuaj no zoo tshaj li qub, tsis tas li ntawd, lawv tsis tshua muaj kev phiv tshuaj. Yuav kom ncav cuag lub hom phiaj siab siab (feem ntau qis dua 140/90), 50% ntawm cov neeg mob ntshav siab yuav tsum tau noj ntau yam tshuaj ntawm lub sijhawm sib txawv. Qhov kev qhia tshuaj no feem ntau tsis muaj txiaj ntsig, vim tias feem ntau cov neeg mob tsis nco qab haus tshuaj ib zaug. Sib xyaw noliprel pab txhim kho txoj kev kho kom zoo, vim nws tsuas noj ib hnub ib zaug.
Leej twg yog tus muab tshuaj
Ntau tshaj li ib nrab ntawm cov neeg tshaj 60 raug mob los ntawm kev kub siab. Txhua xyoo, qhov teeb meem no hnyav zuj zus, vim nyob hauv lub neej niaj hnub muaj ntau thiab ntau qhov kev pheej hmoo rau ua rau muaj kev ntxhov siab ntau ntxiv: kev ntxhov siab, tsis muaj qhov mus taus, hnyav, tsis zoo, tsis huv rau cov pa paug. Kev kub siab yog ib qho tseem ceeb ua rau mob stroke thiab lub plawv, yog li koj yuav tsum tau kho nws tam sim ntawd tom qab kuaj pom.
Kev sib cav tswv yim txog lub siab uas pib haus cov tshuaj noj tau ntev dhau los. Raws li kev lees paub qhov kev faib tawm thoob plaws ntiaj teb, qib siab 120/80 yog suav tias yog qhov qub, thiab qib siab tau pom tias yog 139/89. Theem 1 kub qhia tau pib rau theem 140/90. Nrog rau cov kab mob ntshav qab zib thiab lub raum, cov qis qis dua yog tsawg, cov ntsiav tshuaj tau sau tseg, pib nrog tus lej 130/80. Thaum pib ntawm tus kab mob, lub siab yeej ib txwm muaj ntau zaus, nce tsuas yog qee zaum. Kev siv tshuaj tsis yog tshuaj muaj txiaj ntsig rau lub sijhawm no: kev noj haus, txiav luam yeeb thiab haus cawv, cov haujlwm txhua hnub, poob phaus. Cov tshuaj tau txuas nrog yog tias nws tsis tuaj yeem ua kom lub siab nrog cov ntsuas no.
Raws li cov kws kho mob, thawj zaug, cov neeg mob feem ntau tsuas xav tau ib yam tshuaj nrog ib yam tshuaj. Yog tias kev kho mob zoo li no tsis ua haujlwm, siv ntau cov tshuaj tiv thaiv kabmob lossis ib qho kev sib txuam. Noliprel muaj ib qho zoo tshaj plaws kev sib txuas ntawm cov khoom xyaw nquag, nws txuas nrog ACE inhibitor thiab diuretic.
Cov txiaj ntsig ntawm kev siv tshuaj ua ke:
- Cov tshuaj uas ua Noliprel cuam tshuam rau cov laj thawj ntawm kev txhim kho kev tawg los ntawm ob sab sib txawv, yog li ntawd lawv cov txiaj ntsig ua ke muaj zog dua thiab ruaj khov.
- Kev txo tawm siab yog ua tiav los ntawm kev txhaj tshuaj tsawg dua ntawm cov tshuaj, yog li qhov ua haujlwm tsis muaj kev xav tau tsawg dua.
- Ua tsaug rau qhov sib xyaw ua ke zoo, ib qho tshuaj txo cov kev phiv los ntawm lwm qhov - ib qho diuretic tiv thaiv hyperkalemia, uas tuaj yeem cuam tshuam los ntawm ACE inhibitor.
- Cov nyhuv ntawm kev sib xyaw Noliprel muaj kev loj hlob sai dua.
- Tus neeg mob yuav tsum haus tsuas yog 1 ntsiav tshuaj ib hnub, omissions tshwm sim tsawg dua li thaum noj 2-3 ntau yam tshuaj, yog li cov txiaj ntsig ntawm kev kho mob siab dua.
Qhov ntsuas tsuas yog rau kev siv ntawm Noliprel yog kub siab. Nov yog cov tshuaj uas tsis raug txhaj tshuaj zoo uas tuaj yeem kho tau rau txhua tus neeg mob uas tsis muaj kev sib kis. Cov kev xaiv ntawm qee cov tshuaj noj rau lub siab yog feem ntau nyob ntawm cov kab mob ntshav siab uas tsis sib thooj. Raws li cov lus qhia, Noliprel yog ib qho ntawm cov tshuaj pom zoo rau txo qis hauv cov ntshav qab zib, vim nws muaj ib qho tshuaj zoo rau cov ntshav qab zib - indapamide. Nws kuj tseem ua haujlwm rau cov kev mob metabolic syndrome, mob plawv tsis ua hauj lwm ntev, mob plawv, nephropathy, atherosclerosis.
Cov tshuaj Noliprel li cas?
Kev sib xyaw ua ke ntawm cov tshuaj nquag hauv Noliprel ntsiav tshuaj suav tias tsis yog muaj kuab xwb, tab sis kuj tseem muaj txiaj ntsig zoo. Nws muab cov nyhuv tam sim ntawm 2 qhov ua rau kub siab:
- Cov tshuaj perindopril nyob nrog pawg ACE inhibitor tshuaj. Nws cuam tshuam nrog kev ua haujlwm ntawm renin-angiotensin system, vim los ntawm qhov kev ceev hauv peb lub cev tau tswj hwm. Perindopril txwv tsis pub tsim cov tshuaj hormone angiotensin II, uas muaj cov nyhuv vasoconstrictor muaj zog. Nws tseem ua kom ntev li qhov kev txiav txim ntawm bradykidin - peptide uas ceev cov hlab ntshav. Dab tsi pab rau perindopril: nrog kev siv ntev, nws tsis tsuas yog txo cov kev nyuaj siab, tab sis kuj txo cov kev thauj khoom ntawm cov hlab ntsha thiab lub siab, txhim kho cov mob ntawm cov leeg ntsa, thiab me ntsis txo insulin tsis kam.
- Qhov tshuaj thib ob hauv qhov muaj pes tsawg leeg ntawm Noliprel, indapamide, ua hauj lwm zoo ib yam li thiazide diuretics: nws txhim kho kev tso zis, ntxiv rau kev zam ntawm sodium, chlorine, magnesium, potassium nrog zis. Nyob rau tib lub sijhawm, cov kua dej hauv lub cev txo, uas ua rau poob qis hauv cov hlab ntsha.
Ib qho kev mob tshwm sim ntawm ACE inhibitors, thiab perindopril tshwj xeeb, yog hyperkalemia, uas tuaj yeem ua rau lub siab tsis tuaj yeem ua teeb meem. Tus mob no loj tuaj vim qhov tsis muaj qhov tshwm sim ntawm aldosterone, cov synthesis ntawm cov uas tau tswj hwm los ntawm angiotensin II. Vim tias muaj cov indapamide, uas tshem cov poov tshuaj ntau, thaum noj Noliprel, qhov ntau zaus ntawm hyperkalemia qis dua qis dua nrog kev kho nrog perindopril ib leeg.
Kev siab thiab tawg surges yuav yog ib yam ntawm yav dhau los - pub dawb
Kev mob plawv thiab mob nkees yog qhov ua rau kwv yees li 70% ntawm tag nrho cov neeg tuag hauv ntiaj teb. Xya tawm ntawm kaum tus neeg tuag vim kev txhaws ntawm cov hlab ntsha ntawm lub plawv lossis paj hlwb. Yuav luag txhua qhov teeb meem, qhov laj thawj rau qhov txaus ntshai kawg yog qhov zoo ib yam - lub siab surges vim kub siab.
Nws yog qhov ua tau thiab tsim nyog los daws lub siab, txwv tsis pub muaj dab tsi. Tab sis qhov no tsis kho tus kab mob nws tus kheej, tab sis tsuas yog pab txhawm rau txhawm rau tshawb fawb, thiab tsis yog qhov ua kom muaj tus kab mob.
- Normalization ntawm siab - 97%
- Kev tshem tawm ntawm cov hlab ntsha thrombosis - 80%
- Ntaus tau ntawm lub plawv dhia muaj zog - 99%
- Kom tshem tau mob taub hau - 92%
- Qhov nce hauv lub zog nruab hnub, txhim kho pw tsaug zog thaum hmo ntuj - 97%
Kev tshuaj xyuas los ntawm cov kws kho plawv txog Noliprel feem ntau yog qhov zoo. Lub koob npe zoo ntawm cov tshuaj yog txaus siab los ntawm cov kev tshawb fawb ntau.
Cov ntaub ntawv ntawm kev txiav txim ntawm Noliprel:
- hauv thawj lub hlis ntawm kev kho mob, qib siab poob qis hauv 74% ntawm cov neeg mob, los ntawm lub hlis thib peb - hauv 87%;
- hauv 90% ntawm cov neeg laus cov neeg mob ntshav siab, tom qab kev tswj hwm ib hlis, txo qis dua tuaj yeem txo kom txog 90;
- tom qab ib xyoos ntawm kev siv, ib qho tshwm sim tsis tu ncua nyob hauv 80% ntawm cov neeg mob.
- cov tshuaj ua haujlwm tau zoo hauv cov neeg mob uas xav tau kev kho mob hnyav: ntau qhov tshuaj lossis ntau cov tshuaj tiv thaiv kabmob. Nws qhia tau zoo tshaj plaws nrog kev mob ntshav qab zib nephropathy, ntxiv rau sab laug ventricular hypertrophy.
- Noliprel yog tus cwj pwm los ntawm kev nyab xeeb siab. Qhov tshwm sim ntawm kev phiv loj yog yuav luag tsis txawv ntawm cov placebo.
Hauv kev kho mob ntshav siab, Lub WHO tawm tswv yim kom tsis txhob nce qhov tshuaj ntawm cov tshuaj tiv thaiv ib qho tshuaj kom hloov mus rau kev siv tshuaj sib xyaw, thiab nws raug nquahu kom pib noj tshuaj tsawg. Noliprel ntsiav tshuaj puv nkaus ua raws li cov lus pom zoo no.
Daim ntawv tso tawm thiab ntau npaum li cas
Cov chaw tsim khoom ntawm Noliprel yog lub tuam txhab kev lag luam Fabkis cov Servier, uas paub txog nws cov kev txhim kho hauv kev kho mob rau cov mob plawv thiab ntshav qab zib. Yav dhau los, cov tshuaj tau tsim tawm hauv 2 hom: Noliprel / Noliprel Forte. Txij li xyoo 2006, nws cov pes tsawg leeg tau hloov pauv, lwm ntsev ntawm perindopril tau pib siv. Vim tias qhov no, lub txee lub neej ntawm cov ntsiav tshuaj yam tsis tau poob qhov tsis zoo muaj peev xwm nce ntxiv los ntawm ib nrab. Vim yog qhov sib txawv molecular phaus ntawm ntsev, kev noj cov ntsiav tshuaj yuav tsum tau hloov me ntsis. Tam sim no cov tshuaj muaj nyob rau hauv 3 version:
| Npe | Cov ntsiab lus ntawm cov tshuaj nquag, mg | Noliprel ntau npaum li cas, tus nqi rau 30 ntsiav tshuaj. | Yam tshuaj twg haum | |
| indapamide | perindopril | |||
| Noliprel A | 0,625 | 2,5 | 565 | Noliprel 0.625 / 2 |
| Noliprel Ib Forte | 1,25 | 5 | 665 | Noliprel Forte 1.25 / 4 |
| Noliprel A Biforte | 2,5 | 10 | 705 | Noj ntau npaum li cas, muaj tsis muaj analog ua ntej |
Noliprel yog tsim los ntawm Servier factories nyob hauv Fabkis thiab hauv Lavxias. Cov tshuaj yeeb dej caw rau txhua qhov tshuaj noj tau ua nyob hauv Fab Kis.
Noliprel ntsiav tshuaj muaj lub ntsej muag zoo, muaj kev tiv thaiv los ntawm zaj duab xis daim nyias nyias, rau qhov yooj yim ntawm kev cais ib nrab koob tau muab nrog ib qho kev ceeb toom. Ntim - lub raj mis yas nrog 30 ntsiav tshuaj. Lwm lub chaw tsim khoom ntim tsis tau.
Yuav noj li cas
Nrog rau theem pib lub siab ntawm lub siab, Noliprel tuaj yeem kho tau sai tom qab kuaj pom tus kab mob. Yog tias qhov xwm txheej tsis yog qhov tseem ceeb (nrog rau qib 1 mob ntshav siab), cov tshuaj uas muaj 1 ntu yog qhov zoo dua.
Raws li cov lus qhia, xaiv cov koob tshuaj ntawm Noliprel pib nrog kev siv tshuaj tsawg tshaj plaws. Yog tias lawv tau txais kev pab nws tsis tuaj yeem ua tiav qib siab nce qib, cov tshuaj tau nce ntxiv. Cov tshuaj tsis ncav cuag nws cov nyhuv siab tshaj plaws tam sim ntawd, yog li nws yuav tsum tau tos tsawg kawg 1 hlis ua ntej nce qhov ntau dua.
| Lub sijhawm ua | Ntau tshaj 24 teev, cov nyhuv ntawm cov ntsiav tshuaj tom ntej yog superimposed rau yav dhau los, yog li 1 hla tuaj yeem ua rau nce siab hauv 2-3 hnub. | |
| Siab kawg nkaus | Cov nyhuv ntawm Noliprel nce ntxiv nyob rau hauv 5 teev tom qab kev tswj hwm, tom qab ntawd tseem yuav luag nyob rau tib theem li ntawm 19 teev tom ntej. Tom qab ib hnub, qhov kev ua tau zoo tseem nyob ntawm theem 80%. | |
| Muaj ntau lub sijhawm nkag nyob rau ib hnub | 1 lub sijhawm, kev siv ntau dua yog qhov tsis paub tab. | |
| Yuav haus li cas | Tag nrho los sis faib ua ib nrab, tsis muaj zuaj. Haus nrog dej. | |
| Cov Noj Cov Tshuaj Pom Zoo | Nrog rau kev nyuaj siab tsis tawg | 1 tab Noliprel A. |
| Tawg Roj + Ntshav Qab Zib | Hauv thawj 3 lub hlis - 1 tab. Noliprel A, tom qab uas cov koob tshuaj tuaj yeem muab ob npaug (1 tab. Noliprel Forte). | |
| Tawg siab + lub raum tsis ua haujlwm | Nrog GFR ≥ 60, kev siv tshuaj ib txwm siv. Ntawm 30≤SKF <60, ib koob tshuaj perindopril thiab indapamide yog xaiv cais (kev siv nyiaj monopreparations). | |
| Thaum yuav tau coj thaum sawv ntxov lossis yav tsaus ntuj | Xav pom zoo dua thaum sawv ntxov. | |
| Noj ua ntej lossis tom qab noj mov | Ua ntej noj mov. | |
| Qhov siab tshaj plaws | 1 tab Noliprel A Biforte. Nrog raum tsis ua haujlwm - 1 tab. Noliprel Forte. | |
Cov neeg laus cov neeg mob ntshav siab ua ntej noj Noliprel, cov lus qhia rau kev siv pom zoo tias koj yuav tsum tau kuaj mob kom ntsuas lub raum noj qab haus huv.
Muaj kev phiv ntau
Txhua ACE cov tshuaj tiv thaiv yog suav tias yog tshuaj siv nrog kev nyab xeeb siab. Rau Noliprel, qhov kam rau ua profile tsis txawv ntau ntawm cov placebo.
Phiv los ntawm Noliprel yog:
- hypotension thaum pib ntawm kev tswj hwm thiab nrog kev siv ntau dhau (zaus txog 10%);
- hnoos, ua kom lub neej tsis zoo, tab sis tsis txaus ntshai rau lub ntsws (li ntawm 10%);
- hloov hauv cov ntshav poov tshuaj theem (nce txog 3%);
- mob raum tsis zoo nyob rau hauv muaj muaj pathology ntawm lub raum (txog li 0.01%);
- kev ua txhaum ntawm kev tsim lossis kev loj hlob ntawm tus me nyuam hauv plab (zaus tsis tau txiav txim siab, txij li Noliprel raug txwv thaum cev xeeb tub);
- kev tsis haum rau Noliprel cov cheebtsam, Quincke's edema (txog 10%);
- saj tsis meej (nce txog 10%);
- hemoglobin txo (nce txog 0.01%).
Raws li cov lus qhia, feem ntau cov kev phiv tawm ntawm Noliprel thiab nws cov analogues yog hnoos qhuav, khaus, zoo ib yam li kev ua xua. Nws tshwm sim hauv thawj xyoo ntawm kev kho mob. Qhov ntau zaus ntawm cov xwm txheej no tsis nyob ntawm lub npe cov tshuaj thiab tus neeg mob lub cev noj qab haus huv. Txawm li cas los xij, hnoos yog 2 zaug tsawg dua rau tus txiv neej dua li poj niam (hauv tag nrho pawg ntawm ACE inhibitors, 6% tiv thaiv 14%), thiab Caucasians tsawg dua li nyob rau hauv Asians.
Raws li kev tshuaj xyuas ntawm cov neeg mob noj cov tshuaj, feem ntau hnoos yog tshwm sim los ntawm zuam lossis caj pas, ntawm txoj kab rov tav nws ntxiv. Thaum noj Noliprel, qhov ntau zaus ntawm cov kev mob tshwm sim no yog, raws li kev kwv yees ntau yam, los ntawm 5 txog 12%. Qee zaum cov teeb meem hnoos tuaj yeem daws nrog antihistamines, tab sis tseem muaj li ntawm 3% ntawm cov neeg mob tau yuam kom tsum tsis kho nrog Noliprel.
Qhov thib ob feem ntau cov kev mob tshwm sim ntawm cov tshuaj yog hypotension nyob rau hauv thawj hnub ntawm kev kho. Cov lus qhia rau kev siv qhia tau hais tias qhov kev pheej hmoo siab tshaj plaws rau cov neeg laus cov neeg mob ntshav siab, nrog rau lub cev qhuav dej (nrog rau vim yog siv tshuaj kho tsis tau), pathologies ntawm lub raum thiab lawv cov hlab ntsha. Cov neeg mob uas muaj kev pheej hmoo siab siab yuav tsum pib kho nyob rau hauv kev saib xyuas ntawm kws kho mob, nyiam dua hauv tsev kho mob. Rau lwm tus neeg mob ntshav siab, nws txaus los ua raws li cov kev cai yooj yim: pib txoj kev kho nrog qhov siv tsawg kawg, haus dej ntau dua, txwv ntsev ntau nyob hauv cov zaub mov, thiab nyob hauv tsev thawj hnub.
Noliprel ntsiav tshuaj yuav cuam tshuam rau cov ntshav poov tshuaj. Cov poov tshuaj tsis muaj zog, hypokalemia, tau pom nyob hauv kwv yees li ntawm 2% ntawm cov neeg mob, feem ntau nws yog ua los ntawm kev nkees nkees, mob lossis cramps hauv lub plab hlaub. Qhov zaus ntawm lub xeev rov qab, hyperkalemia, qhia hauv cov lus qhia, yog tsawg dua 1%. Tus mob no feem ntau yog mob ntshav qab zib thiab lub raum pathologies.
Cov txiaj ntsig ntawm Noliprel rau hemoglobin yog qhov tseem ceeb thiab tsis ua rau muaj kev phom sij txog kev noj qab haus huv, feem ntau nws tsuas yog kuaj pom los ntawm cov kev sim.
Saj tsis nyiam yuav ua tau tsis kaj siab. Hauv lawv qhov kev ntsuam xyuas, cov neeg mob ntshav siab piav qhia lawv li qab zib lossis xim hlau tsis hnov qab, txo qis rau hauv qhov qab, thiab tsis tshua muaj qhov hnov zoo thaum lub qhov ncauj tawm ntawm lub qhov ncauj. Thaum muaj mob hnyav, cov kev tsis zoo no ua rau tsis qab los noj mov thiab tsis kam noj Noliprel. Qhov tshwm sim no nyob ntawm qhov koob tshuaj thiab feem ntau ploj nws tus kheej tom qab 3 lub hlis.
Cov Yuav Tsum Muaj
Cov tshuaj sib xyaw ua ke muaj ob peb txoj kev sib txuam ntau dua li cov tshuaj sib cais, vim cov tuam txhab tsim khoom kuaj xyuas kev pheej hmoo ntawm kev siv txhua yam tshuaj yeeb dej caw sib cais.
Cov lus qhia rau kev siv Noliprel nruj me ntsis txwv tsis pub nws siv nyob rau hauv cov xwm txheej hauv qab no:
- Nrog hypersensitivity rau cov tshuaj nquag lossis lwm yam ntawm Noliprel, rau lwm cov tshuaj ntawm ACE inhibitor pawg, rau sulfonamides.
- Yog tias dhau los, thaum noj ACE inhibitors, tus neeg mob tau Quincke edema.
- Nrog hypolactasia: hauv cov ntsiav tshuaj Noliprel txog 74 mg ntawm lactose.
- Hauv menyuam yaus, txij li kev nyab xeeb tsis muaj leej twg ntawm cov tshuaj txuam ntawm cov tshuaj tau kawm.
- Hauv cov neeg mob ntshav qab zib lossis ua rau lub raum tsis ua haujlwm (GFR <60), Noliprel yuav tsum tsis txhob noj ib txhij nrog aliskiren vim muaj tshuaj txuam nrog.
- Hauv cov mob ntshav qab zib nephropathy, Noliprel raug txwv tsis pub noj nrog ua ke nrog sartans (Losartan, Telmisartan thiab analogues), vim tias qhov kev sib txuam no ua rau muaj kev pheej hmoo ntawm hyperkalemia thiab hypotension.
- Vim tias muaj qhov sib xyaw ua ke ntawm diuretic, lub raum thiab lub siab ua haujlwm tsis txaus nyob rau hauv theem loj kuj tseem contraindications. Ntawm kev pheej hmoo siab ntawm lub raum tsis ua haujlwm, kev tshuaj xyuas ntxiv yog tsim nyog: kev ntsuam xyuas tsis tu ncua (txhua 2 hlis) ntsuas cov poov tshuaj thiab ntshav creatinine.
- Lub sijhawm ntawm GW. Cov tshuaj inhibits lactation, tuaj yeem ua rau hypokalemia nyob rau hauv tus menyuam, hypersensitivity rau sulfonamides. Qhov phom sij yog qhov tshwj xeeb tshaj nyob hauv thawj lub hlis ntawm lub neej. Cov lus qhia rau kev siv pom zoo hloov Noliprel nrog lwm tus, ntau tus neeg kawm hypotensive tus neeg sawv cev rau lub sijhawm ntawm kab mob siab B.
- Thaum cev xeeb tub, Noliprel yuav muaj qhov tsis zoo rau tus me nyuam hauv plab. Perindopril hla lub cev me nyuam cov ntshav thiab ua rau kev loj hlob ntawm txoj kev loj hlob. Hauv thawj lub lis piam, thaum cov kabmob tau tsim, Noliprel tsis muaj kev phom sij, yog li tsis tas yuav txiav tawm qhov kev xeeb menyuam tsis tau npaj tseg. Tus poj niam tau maj nrawm mus rau lwm qhov kev tiv thaiv tshuaj tiv thaiv thiab muab tso rau kev tswj hwm tshwj xeeb kom paub sai sai ua txhaum cai. Pib txij lub sijhawm thib ob lub sijhawm, Noliprel tuaj yeem ua rau kev mob ntshav siab, lub raum tsis ua haujlwm hauv tus menyuam, ntshav lossis ntshav qis ntawm lub ntsws nyob rau ntawm tus menyuam mos, oligohydramnios, thiab qhov tsis txaus.
- Nrog kev sib xyaw ntawm Noliprel nrog cov neeg sawv cev rau kev kho mob ntawm arrhythmias, antipsychotics, antipsychotics, erythromycin, moxifloxacin, tachycardia yuav tshwm sim. Cov npe tag nrho ntawm cov tshuaj lom txaus ntshai tau muab rau hauv cov lus qhia.
Qhov sib xyaw ua ke ntawm haus cawv nrog cov tshuaj tsis zoo. Ethanol tsis cuam tshuam nrog cov khoom hauv Noliprel, yog li ntawd, tsis yog nruj contraindication rau nws siv.Txawm li cas los xij, nrog kev siv tas li, haus dej cawv provokes tas li nce lub siab, uas yog, nws ua txhaum rau Noliprel. Raws li kev txheeb xyuas, txawm tias haus cawv ib zaug nrog cov tshuaj no ua rau muaj kev pheej hmoo siab thiab muaj mob tsis zoo rau ntau hnub.
Kev sib piv thiab hloov chaw
Cov tshuaj tiv thaiv tag nrho yog cov tshuaj uas muaj cov tshuaj zoo ib yam rau hauv tib lub tshuaj noj npaum li qub. Lub zog ntawm cov tshuaj no zoo ib yam, yog li lawv tuaj yeem hloov Noliprel lub sijhawm twg los tau, lub sijhawm npaj thiab xaiv cov koob tshiab tsis tas yuav tsum.
Tag nrho cov analogues ntawm Noliprel yog:
| Tshuaj | Chaw tsim tshuaj paus | Tsuas tshuaj | Pob nqi 30 ntsiav tshuaj rau qhov tsawg kawg / ntau kawg koob, tshiav. | ||
| 0,625/2 | 1,25/4 | 2,5/8 | |||
| Ko-perineva | Krka (Russia) | + | + | + | 470/550 (875/1035 rau 90 pcs.) |
| Perindid | EdgeFarma (Is Nrias teb) | + | + | - | 225/355 |
| Perindopril PLUS Indapamide | Izvarino (Russia) | + | + | + | 280/520 |
| Indapamide / Perindopril-Teva | Teva (Ixayees) | + | + | - | 310/410 |
| Co parnawel | Atoll (Russia) | + | + | - | 370/390 |
| Indapamide + Perindopril | Hnub Qub Qaum Teb (Russia) | + | + | + | tsis yog muag |
| Co-perindopril | Pranapharm (Russia) | + | + | + | |
| Perindopril-Indapamide Richter | Khede-oos Richter (Hungary) | + | + | - | |
| Perindapam | Sandoz (Slovenia) | + | + | - | |
Cov lus pom zoo tshiab txog kev kho cov mob ntshav siab qhia tias kev hloov pauv tshuaj ntau dhau, kev hloov tshuaj ntau ntau yog qhov tsis xav tau thiab tuaj yeem ua rau nce siab. Kev noj ib hom tshuaj suav yog suav tias ua tau zoo dua li kev kho nrog ob yam tshuaj nrog tib cov tshuaj muaj yeeb tshuaj. Yog tias nws tsis tuaj yeem yuav qhov Noliprel uas tau sau tseg, nws yog qhov zoo dua los hloov nws nrog tag nrho cov analogues. Hauv qhov no, nws raug nquahu kom xaiv cov tshuaj los ntawm cov neeg muaj npe hauv European thiab cov chaw lag luam kws tshaj lij ntawm Lavxias.
Hauv cov xwm txheej hnyav, koj tuaj yeem hloov Noliprel nrog ob ntsiav tshuaj. Qhov tseem ceeb tshaj plaws yog xaiv cov tshuaj ntau npaum li cas, nws yuav tsum sib raug nrog cov tus kws kho mob tau sau tseg.
Cov kev xaiv rau cov kev hloov zoo li no:
| Muaj pes tsawg leeg | Tshuaj | Nqi rau 30 ntsiav tshuaj |
| tsuas yog perindopril | Perindopril los ntawm cov tuam txhab tshuaj Lavxias Atoll, Pranapharm, Lub Hnub Qub Qaum Teb, Biochemist | 120-210 |
| Perindopril, Teva | 245 | |
| Prestarium, Servier | 470 | |
| Perineva, Krka | 265 | |
| indapamide nkaus xwb | Indapamide los ntawm Pranapharm, Canonpharm, Welfarm | 35 |
| Indapamide, Teva | 105 | |
| Indapamide, Heropharm | 85 | |
| Arifon, Servier | 340 |
Piv nrog tshuaj zoo sib xws
Txhawm rau kom tsis txhob muaj qhov siab, feem ntau cov neeg mob ntshav siab yuav tsum tau noj 2 rau 4 tshuaj. Thaum pib mob, sartans lossis ACE inhibitors (pr-pril) yog cov kws kho mob, vim lawv tiv thaiv ob lub raum thiab lub plawv ntau dua li lwm yam tshuaj. Sai li lawv dhau los ua tsis txaus, tshuaj diuretics yog ntxiv rau tus neeg mob: cov rov qab kho mob feem ntau yog kev pom zoo rau lub raum tsis ua haujlwm, thiazide yog qhov pom zoo rau nws qhov tsis tuaj.
Cov kev sib xyaw ua ke yog suav tias yog qhov kev xaiv zoo tshaj plaws, uas yog, kev sib piv ntawm ob peb yam tshuaj lom tau laij thiab txheeb xyuas qhov tseeb hauv kev kuaj mob hauv ib lub ntsiav tshuaj.
Kev sib xyaw ntawm thiazide diuretic thiab los ntawm kev yoov yog nrov tshaj plaws thiab ib qho muaj zog tshaj plaws. Nws ua tau zoo rau cov neeg laus cov neeg mob ntshav siab uas muaj lub plawv tsis ua haujlwm. Feem ntau, hydrochlorothiazide yog ua ke nrog enalapril (Enap, Enafarm, Enam H), fosinopril (Fozid, Fozikard), lisinopril (Lisinoton, Lisinopril), captopril (Caposide). Lub ntsiab zoo ntawm kev sib xyaw no yog qhov tsawg dua cov kev mob tshwm sim. Ntawm cov tshuaj no, Noliprel suav tias yog ib qho kev nyab xeeb thiab muaj peev xwm tshaj plaws. Zoo sib xws hauv txoj hauv kev rau cov pawg dhau los ntawm cov tshuaj yog kev sib txuas ntawm diuretics nrog sartans - Lozartan N, Lozap Plus, Valsacor, Duopress thiab lwm tus.
Nws tsis tuaj yeem xaiv qhov ua tau zoo tshaj plaws los ntawm cov kev sib txuas saum toj no, txij li lawv tau nyob ze rau hauv lub zog ntawm kev ua. Tsis muaj ib qho kev tshawb fawb nkaus xwb uas yuav ua pov thawj qhov zoo tiag tiag ntawm ib cov tshuaj dhau tas.
Noliprel hloov pauv nrog lwm yam tshuaj muaj sia (txawm tias lawv nyob hauv pab pawg tib yam) tuaj yeem noj tsuas yog tom qab sab laj nrog kws kho mob. Thaum hloov mus rau lwm cov tshuaj, koj yuav tsum rov xaiv cov koob tshuaj thiab ntau zaus dua li niaj zaus, tswj lub siab kom tiv thaiv hypotension ua tau.
