Ntshav qab zib MV yog tshuaj siv dav dav hauv kev kho mob ntshav qab zib hom 2. Nws yog tshuaj feem ntau rau cov neeg mob ntshav qab zib tsis muaj qhov hnyav dhau thiab tshaj tawm ntawm cov ntaub so ntswg mus rau insulin, vim tias ntsiav tshuaj pab txhawb rau maj mam hnyav nce thiab txhawb cov txiav ua ke.
Cov tshuaj tsis nto npe ntawm cov tshuaj yog gliclazide. "Diabeton MV" yog lub npe kev lag luam ntawm cov tshuaj ntawm Fabkis lub chaw muag tshuaj Servier, ntawm daim ntawv nyiam, cov tshuaj tsis yog feem ntau muab rau hauv lub tsev muag tshuaj, vim tias lawv muaj nqi ntau dua li cov generics (Diabinax, Glidiab, Diabefarm), uas yog tsim tawm ntawm gliclazide.
Kab laum MV txhais tau tias Diabeton nrog kev hloov kho tso tawm thiab cov nquag ua haujlwm tsis pom tshwm sim nws tus kheej tam sim ntawd, tab sis thaum nruab hnub, nyob hauv qhov sib npaug.
Tus neeg tau txais txiaj ntsig ntawm Diabeton MV
Yog tias peb sib piv cov tshuaj nrog lwm cov qauv ntawm sulfonylurea series, tom qab ntawd thaum tsis tau tshaj tawm cov lus txhoj puab heev, nws cov hauj lwm zoo yuav siab dua.
- Diabeton MV nti tawm zoo rov qab glycemic tshuav nyiaj li cas;
- Gliclazide stimulates lub sijhawm 2 ntawm cov tshuaj hormones zais pa, tam sim ntawd mus txog qhov siab kawg thaum tau txais cov khoom noj carbohydrates.
- Cov tshuaj txo txoj kev pheej hmoo ntawm thrombosis;
- Qhov ntxim nyiam ntawm hypoglycemia ntawm cov kev mob tshwm sim yog txo rau 7% (rau lwm cov tshuaj ntawm sulfonylurea pawg, qhov kev pheej hmoo yog ntau dua);
- Kev noj tshuaj yog ib-zaug, yooj yim rau cov ua haujlwm ntshav qab zib thiab tsis nco qab txog kev so haujlwm;
- Kev tso tawm qeeb qeeb ntawm cov tshuaj tsis pab rau qhov hnyav nce li cov ntsiav tshuaj Diabeton;
- Tus kws kho mob uas tsis tau paub dua txog cov tshuaj no yuav hloov kho qhov yooj yim, vim tias qhov kev pheej hmoo loj yuav tshwm sim tsawg;
- Gliclazide lwg me me muaj cov yam ntxwv ua antioxidant;
- Cov tshuaj muaj cov txheeb cais zoo ntawm cov teebmeem tsis xav tau - nce txog 1%.
Nrog rau cov lus pov thawj zoo ntawm cov tshuaj, cov tshuaj kuj muaj qhov tsis zoo.
- B ua lub luag haujlwm rau insulin ntau lawm yog depleted.
- Rau 2-8 xyoo (nyob ntawm lub cev qhov hnyav, sai dua rau cov neeg nyias), tus mob ntshav qab zib muaj tus mob thib 2 kis tau tus mob ntshav qab zib hom 1 ntau dua.
- Cov tshuaj tsis tshem tawm cov ntaub so ntswg ua kom tsis muaj zog rau cov insulin, tab sis rau qee yam txawm tias txhim kho nws.
- Kev txhim kho glycemic profile tsis tuaj yeem lav qhov txhim kho ntawm kev tuag los ntawm cov ntshav qab zib (raws li kev tshawb fawb los ntawm lub chaw nto moo thoob ntiaj teb ADVANCE).
Txhawm rau tsis txhob yuam kom lub cev xaiv ntawm cov teeb meem los ntawm cov txiav thiab kab mob ntawm lub plawv, cov ntsiav tshuaj yuav tsum tau pab los ntawm kev tswj hwm koj kev noj haus thiab cov leeg ua si.
Kev ua neej hloov kho kuj tseem yuav txo cov kev pheej hmoo mob plawv rau hauv txoj kev loj hauv glycemia, poob rau hauv cov ntshav siab, rog rog, thiab lipid metabolism tsis meej.
Kev piav qhia ntawm daim ntawv muaj pes tsawg leeg thiab noj tshuaj
Lub ntsiab ntawm cov mis yog gliclazide - ib yam tshuaj nrog hypoglycemic lub peev xwm, tus sawv cev ntawm sulfonylurea chav kawm ntawm cov tshuaj. Cov tshuaj muaj pes tsawg leeg ntxiv nrog kev ua kom ntev ntawm lactose monohydrate, maltodextrin, hypromellose, magnesium stearate, silicon dioxide.
Cov ntsiav tshuaj tuaj yeem txheeb xyuas tau los ntawm oval cov duab nrog cov kab sib faib thiab cov tsiaj ntawv luv "DIA 60" rau ntawm ib sab.
Cov tshuaj tau muab ntim rau hauv cov hlwv rau 15-30 daim, hauv ib lub thawv ntawv nrog rau cov lus qhia yuav muaj 1-4 daim hlau zoo li ntawd.
Cov tshuaj kws kho mob muab tawm. Rau Diabeton MV, tus nqi tsis yog qhov siv nyiaj ntau tshaj plaws, rau 30 ntsiav tshuaj qhov nruab nrab ntawm 300 rubles yuav tsum tau them. Lub sijhawm tag sij hawm tshaj tawm los ntawm tus tsim khoom lag luam tsis pub ntau tshaj 2 xyoos. Cov tshuaj tsis tas yuav tshwj xeeb rau kev khaws cia.
Cov Tshuaj Hauv Tshuaj
Sulfonylurea tshuaj, uas suav nrog Diabeton MV, txhawb kev ua ub no ntawm lub txiav thiab nws lub hlwb b, uas tswj cov tshuaj insulin ntau lawm. Qib kis ntawm cov tshuaj no yog nruab nrab, piv txwv li, tshuaj ntsuab Maninil muaj kev txhoj puab heev.
Cov tshuaj yuav pab tau zoo nrog rau cov cim ntawm kev ploj ntawm kab mob ntawm lub txiav, thaum tsis muaj kev tawm tsam nws tsis muab qib ntawm insulin uas yuav tsum tau los them rau kev mob glycemia. Nrog rau tej theem ntawm kev rog, cov tshuaj tsis tau hais tseg lawm.
Diabeton MV rov qab ua thawj theem ntawm cov tshuaj insulin yog tias qhov poob qis hauv nws qhov kev ua tau zoo raug pom hauv lub cev. Hauv cov ntshav qab zib uas muaj hom mob 2, cov tshuaj pab txhim kho cov tshuaj insulin thaum ntxov thaum cov carbohydrates nkag mus rau hauv lub cev thiab rov kho theem ob ntawm lub voj voog.
Ntxiv nrog rau qhov kev lees paub txo qis hauv glycemic indices, kev noj tshuaj pab cuam tshuam rau kev noj qab haus huv ntawm cov hlab ntsha thiab cov ntshav khov. Los ntawm kev txo cov platelet adhesion (kev sib sau ua ke), nws txo txoj kev pheej hmoo ntawm vascular thrombosis, ntxiv dag zog rau lawv los ntawm sab hauv, muab kev tiv thaiv angioprotective.
Cov tshuaj cuam tshuam cawv algorithm yog cov qhia tshwj xeeb.
- Ua ntej, kev txiav txim siab yog kho mus tso tawm cov tshuaj hormones rau hauv cov hlab ntshav;
- Tom qab ntawd theem pib ntawm insulin secretion yog simulated thiab rov qab;
- Txhawm rau kom txo cov kev tsim cov ntshav txhaws hauv cov hlab ntsha me, platelet kev ua haujlwm yog txo;
- Nyob rau hauv parallel, muaj qee cov nyhuv antioxidant.
Kev siv tshuaj ib zaug muab qhov zoo tshaj plaws ntawm cov tshuaj glibenclamide ib hnub. Qib theem ntawm C-peptide thiab insulin yog tsim nyob rau hauv lub cev tsis tau ntxov dua tom qab 2 xyoos ntawm kev noj tshuaj tas li.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog nqus rau hauv lub plab zom mov tag nrho. Hauv cov ntshav, nws cov ntsiab lus accumulates maj dhau 6 lub sijhawm. Cov qib ua tiav tau ntev li 6 mus rau 12 teev. Kev hloov pauv rau ntau yam kabmob ntshav qab zib muaj tsawg.
Tib lub sij hawm nrog kev haus tshuaj ntawm cov zaub mov noj rau hauv lub cev, pharmacokinetic cov yam ntxwv ntawm gliclazide tsis hloov. Kev sib txuas lus nrog cov ntshav protein yog khaws cia ntawm 95%, Vd - txog 30 liv.
Gliclazide metabolism tshwm sim hauv lub siab, tsis muaj cov tshuaj lom metabolites hauv cov hlab ntshav.
Lawv lub raum raug tshem tawm (nce txog 1% hauv tib qho). T1 / 2 ntawm gliclazide sib txawv nyob rau thaj tsam ntawm 12-20 teev.
Thaum cov koob tshuaj tau nce mus rau qhov siab tshaj plaws (120 mg), thaj chaw hauv qab kab cim ntawm kev sib raug zoo ntawm lub sijhawm thiab kev faib tawm nce rau hauv kev faib ncaj qha.
Kev ntsuas rau siv
Kev txhim kho tshiab ntawm cov tshuaj nrog lub txiaj ntsig ntev ntev tau tsim kho los kho cov glycemic profile thiab tiv thaiv kev mob ntshav qab zib (mob stroke, retinopathy, mob plawv, nephropathy, mob caj dab).
Nws yog tshuaj rau cov neeg mob ntshav qab zib nrog lub cev nyhav nrog hom 2 mob ntshav qab zib ntawm kev mob hnyav thiab mob hnyav uas tsis muaj cov tsos mob ntawm cov ntaub so ntswg tiv thaiv cov tshuaj insulin.
Nws kuj tseem siv los ntawm cov kis las los txhim kho qhov rhiab ntawm cov ntaub so ntswg mus rau insulin, uas ua kom cov leeg muaj zog.
Raws li pib tshuaj rau tus mob ntshav qab zib, Diabeton MV tsis haum. Nws kuj tseem ua tsis zoo rau kev sau tshuaj rau cov rog rog, vim tias tus txiav ua haujlwm twb ua haujlwm ntawm kev txwv ntawm lawv lub peev xwm, ua 2-3 qhov kev cai ntawm cov tshuaj insulin uas tsis tuaj yeem tiv thaiv kev mob hnyav. Mob ntshav qab zib MV nyob rau hauv cov ntaub ntawv no muaj peev xwm txawm provoke kev tuag (los ntawm mob plawv).
Txhawm rau kawm txog kev sib raug zoo ntawm kev xaiv ntawm cov tshuaj xub thawj rau kev tswj hwm tus mob ntshav qab zib hom 2 thiab kev pheej hmoo ntawm kev tuag, kev kawm tshwj xeeb tau ua. Cov lus xaus yog pom tseeb.
- Hauv cov neeg mob ntshav qab zib tau txais tshuaj sulfonylurea, piv nrog cov neeg tuaj yeem noj tshuaj metformin, qhov tshwm sim ntawm kev tuag los ntawm cov mob plawv yog 2 zaug ntau dua, mob plawv (CHD) - 4.6 zaug, ntshav hlwb khiav (NSC) - 3 zaug.
- Txoj kev pheej hmoo ntawm kev tuag los ntawm NMC thiab mob plawv ua rau muaj ntau dua rau cov neeg mob ntshav qab zib uas tau haus tshuaj raws li glibenclamide, glycvidone, glyclazide dua li cov uas tau kho nrog metformin.
- Piv nrog rau cov pab pawg kho nrog glibenclamide, cov neeg koom nrog tau txais gliclazide qhia cov txiaj ntsig hauv qab no: ib qho txo 20% ntawm kev tuag tag nrho, thiab 40% txo kev tuag los ntawm UC thiab CCC.
Yog li, kev xaiv ntawm Diabeton MV ua tus thawj kab tshuaj, zoo li lwm yam tshuaj sulfonylurea, muaj feem yuav tuag nyob rau hauv 5 xyoo 2 zaug, khwv tau myocardial infarction - 4,6 zaug, mob hlwb - 3 zaug. Nrog cov mob ntshav qab zib uas nyuam qhuav soj ntsuam, metformin ua thawj cov kev pabcuam khomob yog qhov zoo tshaj plaws.
Hauv kev ncaj ncees, nws yuav tsum raug sau tseg tias nrog rau peb lub xyoo lossis ntau dua ntawm kev haus ntshav qab zib MV, qhov kev pheej hmoo ntawm tau txais atherosclerosis tau txo qis. Lwm tus neeg sawv cev ntawm hom tshuaj no tsis tau muaj cov txiaj ntsig zoo sib xws. Lub antisclerotic muaj peev xwm ntawm Diabeton MV tuaj yeem piav qhia los ntawm qhov muaj nyob rau hauv nws cov muaj pes tsawg tus antioxidants uas tiv thaiv cov ntaub so ntswg los ntawm oxidation.
Cov txiaj ntsig thiab mob loj ntawm Diabeton - hauv video:
Cov Yuav Tsum Muaj
Mob ntshav qab zib MV yog ib hom tshuaj tshiab tshiab nrog cov neeg ua haujlwm siab. Nws txawv ntawm tag nrho cov analogues ntawm sulfonylurea chav kawm ntawv nyob rau hauv cov nqe lus ntawm kev txhim kho ntawm cov teeb meem thiab ib feem pua tsawg ntawm cov kev mob tshwm sim.
Tab sis, zoo li ib yam tshuaj hluavtaws, gliclazide muaj ib tug xov tooj ntawm contraindications:
- Cov siab nkag siab zoo rau cov feem ntawm cov qauv thiab cov tshuaj ntawm sulfonylurea series feem ntau;
- Ntshav Qab Zib Hom 1;
- Cov mob ntawm ketoacidosis uas mob ntshav qab zib, tsis nco qab thiab precoma;
Qhov hnyav ntawm cov kab mob pathology ntawm lub raum thiab mob siab, thaum hloov pauv mus rau insulin;- Cev xeeb tub thiab lactation;
- Concurrent kev kho mob nrog miconazole;
- Lub hnub nyoog txog 18 xyoo.
Qhov hnyav ntawm cov kab mob pathology ntawm lub raum thiab mob siab, thaum hloov pauv mus rau insulin;Cov tshuaj muaj lactose, yog li nws tsis yog qhia rau nws tsis txaus siab, rau cov piam thaj-galactose malabsorption, galactosemia. Nws tsis pom zoo kom muab cov tshuaj danazol thiab phenylbutazone nrog Diabeton MV.
Cev xeeb tub
Tsis muaj kev paub dhau los hauv kev kho tus poj niam cev xeeb tub nrog gliclazide, nrog rau cov ntaub ntawv ntawm kev kho mob ntawm hom kab mob ntshav qab zib no nrog sulfonylurea cov tshuaj feem ntau.
Hauv kev sim rau cov poj niam tsiaj, qhov tshwm sim teratogenic ntawm gliclazide tsis tau tshwm sim.
Txhawm rau txo qis kev pheej hmoo ntawm kab mob plab yug me nyuam, yuav tsum tau tshuaj xyuas tas li thiab kev kho mob ntshav qab zib hom 2 xav tau. Qhov ncauj tshuaj qog ntshav hauv qhov ncauj tsis tau siv rau lub sijhawm no, cov poj niam cev xeeb tub tau hloov mus rau hauv insulin thiab nws yog qhov zoo tshaj los ua qhov kev hloov pauv no txawm nyob rau theem ntawm kev npaj xeeb tub.
Tsis muaj cov ntaub ntawv hais txog kev nkag mus ntawm gliclazide mus rau niam mis, qhov txaus ntshai ntawm neonatal hypoglycemia tseem tsis tau tsim, vim li no, thaum kho nrog Diabeton MV, kev pub niam mis yog contraindicated.
Tsis muaj pov thawj rau kev ua haujlwm thiab kev nyab xeeb ntawm kev siv Diabeton MV rau cov menyuam yaus, yog li ntawd, cov tshuaj kuj tseem tsis tau siv rau cov neeg mob ntshav qab zib qis dua 18 xyoo.
Sab sij huam
Diabeton MV muaj kev paub dhau los ntawm kev siv nrog qhov tsawg kawg ntawm kev sib txuam thiab cov kev mob tshwm sim, lub ntsiab yog qhov uas suav hais tias yog hypoglycemia, thaum lub ntsej muag glucometer nyeem poob qis dua cov phiaj.
Koj tuaj yeem paub qhov txawv xeev txaus ntshai los ntawm:
- Mob taub hau thiab kiv taub hau;
- Hma qab los noj mov;
- Dyspeptic cuam tshuam;
- Poob lub zog, tsis muaj zog;
- Kev tawm hws ntau heev;
- Lub plawv dhia ceev tsis zoo;
- Kev poob siab, zoo siab lub xeev, kev nyuaj siab;
- Cov tshuaj tiv thaiv adrenergic, tshee hnyo;
- Hais lus tsis meej, delirium;
- Pom kev tsis zoo;
- Mob leeg pob txha;
- Txwv tsis pub xeev, poob peev ntawm yus tus kheej;
- Tsaus muag, tsis nco qab.
Nrog ib daim ntawv me me ntawm hypoglycemia, tus neeg raug muab cov qab zib, nrog rau daim ntawv hnyav, yuav tsum tau mus pw hauv tsev kho mob sai. Lub xeev ntawm hypoglycemia yog txaus ntshai thiab rov tshwm sim, yog li nws yog qhov tseem ceeb los tswj kev noj qab haus huv tom qab zoo los ntawm tus mob.
Los ntawm txoj kev, piv nrog cov pa Diabeton, nws cov tshuaj (nrog rau kev tso tawm qeeb) tso cai rau koj faib cov teeb meem hauv lub cev ntau tusyees. Qhov no txo cov kev pheej hmoo ntawm hypoglycemia.
Ntxiv rau cov ntshav qog ntshav qab zib, muaj lwm qhov tsis pom tshwm sim:
- Urticaria, ua pob ua xua, Quincke's edema;
- Kev ua tsis ncaj ntawm lub plab zom mov;
- Kev tsis txaus siab ntawm cov ntshav hauv daim ntawv ntawm ntshav liab, txo qis hauv cov qe ntshav dawb;
- Lub qhov muag pom ib ntus tsis zoo vim muaj qhov sib txawv ntawm glycemia, ntau zaus thaum hloov kho rau cov tshuaj;
- Ntxiv kev ua haujlwm ntawm daim siab enzymes AST thiab ALT, hauv qee kis, kab mob siab.
Yog tias Diabeton MV tau raug siv es tsis txhob siv lwm yam tshuaj kho ntshav qab zib, nws yog ib qho tseem ceeb los saib xyuas glycemic rau ob lub lis piam txhawm rau txhawm rau tiv thaiv qhov kev txiav txim siab ntawm qhov cuam tshuam ntawm ob yam tshuaj phom sij rau hypoglycemia.
Thaum lub sijhawm kev sim kho mob ntawm lub chaw muaj npe zoo ADVANCE, qhov tsis tseem ceeb (los ntawm qhov kev xav tau ntawm qhov sib txawv) qhov sib txawv ntawm cov kev tswj hwm thiab pawg sim tau pom. Qhov ntau zaus thiab qhov mob ntawm cov hypoglycemia yog tsau tsawg. Feem ntau ntawm cov ntshav ntawm hypoglycemia tau sau tseg tiv thaiv keeb kwm ntawm kev kho txoj hauv txoj hauv kev nrog kev npaj tshuaj insulin.
Qhia Txog Kev Sib Koom Tes Nrog Tshuaj
Txhim kho cov kev ua ntawm Diabeton MV miconazole (ob qho tib si hauv kev siv tshuaj thiab thiab siv sab nraud). Kev sib xyaw ua ke yog ncaj qha contraindicated, raws li nws tuaj yeem ua rau hypoglycemia.
Nws tsis pom zoo kom muab cov gliclazide nrog phenylbutazone. Nrog kev tswj hwm kev tswj hwm, hypoglycemic muaj peev xwm ntawm sulfonylurea derivatives yog txhim kho: kev tshem tawm yeeb tshuaj qeeb qeeb, phenylbutazone hloov chaw nws los ntawm cov protein ligament. Yog tias tsis muaj kev hloov pauv rau cov tshuaj, nws yog ib qho tsim nyog yuav tau kho qhov kev txhaj tshuaj ntawm gliclazide thiab ua tib zoo saib xyuas glycemia rau tag nrho lub sijhawm ntawm kev kho mob thiab tom qab qhov kawg.
Nce kev pheej hmoo ntawm glycemia ethanol thiab tshuaj raws nws. Rau lub sijhawm ntawm kev kho mob nrog Tus Mob Ntshav Qab Zib MV, nws yog ib qho tsim nyog yuav tsum tso tseg cov dej cawv thiab cov tshuaj kho mob raws cov cawv.
Kev sib xyaw nrog cov tshuaj tiv thaiv kab mob tau muab nrog kev ceev faj: insulin, biguanides, acarbose, diazolidinediones, GLP-1 antagonists, DPP-4 inhibitors, PP-blockers, MAO thiab ACE inhibitors, fluconazole, sulfonamide tshuaj, NPs. Ib qho ntawm cov kev sib txuas ua ke nce qhov hypoglycemic muaj peev xwm ntawm Diabeton MV thiab xav tau koob tshuaj titration thiab saib xyuas qhov tseeb ntawm glycemic profile.
Nws tsis muaj zog lub peev xwm ntawm Diabeton MV Danazole, uas ua rau nce siab ntawm cov suab thaj hauv ntshav. Nrog rau kev siv ncaj qha, ntau npaum li cas titration thiab glycemic saib xyuas yuav tsum tau rau tag nrho cov chav kawm ntawm kev kho mob thiab tom qab nws. Qhov xwm txheej zoo sib xws tau pom nrog iv txhaj tshuaj b-adrenergic agonists.
Glyclazide + chlorpromazine complexes yog kho nrog ceev faj. Hauv kev txhaj tshuaj ntau, cov tshuaj tiv thaiv kab mob txo qis insulin ntau lawm, pab kev txuam nrog cov piam thaj hauv cov ntshav ntawm cov ntshav. Nws yog qhov tsim nyog los laij cov tshuaj ntau npaum li cas.
GCS thiab tetracosactide nrog rau txhua txoj hauv kev thov (pob qij txha, tawv nqaij, lub ntsaum tawm tswv yim) nce ntshav qab zib, ua rau ketoacidosis tshwm sim, uas txo qis kev kam rau cov khoom lag luam carbohydrate. Nyob rau thawj theem ntawm txoj kev kho mob, maj mam txhaj ib feem kaum thiab kev soj ntsuam ntawm lub ntsej muag glucometer rau tag nrho lub sijhawm ntawm kev sib koom tes thiab tom qab nws tsim nyog.
Txoj kev siv
Txog rau Tus Mob Ntshav Qab Zib MV, cov lus qhia rau kev siv pom zoo tias cov neeg mob ntshav qab zib noj tshuaj thaum sawv ntxov, nrog rau noj tshais. Ib yam li txhua yam tshuaj tiv thaiv kev tiv thaiv kab mob, tus endocrinologist xaiv cov koob tshuaj tus kheej, suav txog qhov tshwm sim ntawm kev ntsuas, theem ntawm ntshav qab zib, kab mob sib kis, lub cev tawm tsam cov tshuaj.
Thaum ib koob tshuaj twg (ntawm 30 txog 120 mg, uas yog 0.5-2 ntsiav tshuaj), noj gliclazide yog ib leeg. Yog tias lub sijhawm tau tawg, muab ob npaug rau noj yog qhov txaus ntshai - lub cev xav tau lub sijhawm los nqus tag nrho, yam tsis muaj kev xav tsis zoo, qhov tsis tuaj yeem.
Hauv qhov qauv txheem, qhov pib siv tshuaj yog Ѕ tab. (30 mg). Rau cov ntshav qab zib ntawm lub hnub nyoog paub tab, koob tshuaj feem ntau tsis tsim nyog.
Yog tias qhov kev cai zoo li no muab kev tswj tiav glycemia, nws tuaj yeem siv los ua kev kho mob. Nrog kev tswj tsis tau zoo, qhov tshuaj kho tau kho, nqa cov txheej txheem txhua hnub rau 60.90 thiab txawm 120 mg. Kev noj tshuaj titration yog nqa tawm tom qab 30 hnub - nws yuav siv sij hawm ntau heev los soj ntsuam qhov ua tau zoo ntawm qhov xaiv xaiv.
Yog tias tus mob ntshav qab zib tsis muaj pauv li 2 vas thiv, txoj cai ib ntus ua tau tsis pub dhau ib nrab ib hlis. Qhov siab tshaj uas tau tso cai kho tshuaj ntawm gliclazide yog 120 mg.
Yog tias tus mob ntshav qab zib tau hloov mus los ntawm cov neeg mob ntshav qab zib sai sai nrog kev tso tawm sai sai ntawm gliclazide mus rau ib qho tshuaj tiv thaiv ntev, tom qab ntawv 80 mg Diabeton ntsiav tshuaj tuaj yeem hloov nrog cov koob tshuaj zoo sib xws nrog lub siab ntev ntawm 60 mg lossis 30 mg.
Thaum hloov lwm txoj kev kho mob glycemic nrog Diabeton MV, kev kho mob yav dhau los thiab lub sijhawm rau kev tshem tawm cov tshuaj yog muab rau hauv tus account. Feem ntau tsis tas yuav tsum muaj kev sib hloov ua ntu zus. Qhov pib koob tshuaj yog txiav txim siab ntawm 30 mg nrog kev kho me ntsis yog tias qhov tshwm sim ntawm kev kho tsis zoo.
Yog tias T1 / 2 ntawm cov tshuaj dhau los ntev, thiaj li yuav zam tau qhov kev cuam tshuam ntawm kev cuam tshuam uas ua rau lub plawv tsis muaj zog, yuav tsum tau txais ib qho ntawm qhov kev kawm. Lub hauv paus pib ntawm Diabeton MV kuj tseem yog kev txiav txim yam tsawg kawg - 30 mg nrog tau muaj kev cog lus ntxiv.
Diabeton MV tuaj yeem siv hauv kev kho mob nyuaj. Txhawm rau txhim kho hypoglycemic muaj peev xwm siv insulin, biguanides, b-glucosidase inhibitors. Yog tias qhov ua tsis tiav, cov koob tshuaj insulin tau teev tseg.
Cov lus pom zoo ntxiv
Cov neeg mob ntshav qab zib nrog lub raum pathologies nyob rau hauv daim ntawv me thiab mob nyhav tsis pom zoo rau koob tshuaj feem ntau, nws tsuas yog ib qho tseem ceeb los soj ntsuam glycemia thiab lub raum kev ua tau zoo.
Kev saib xyuas tshwj xeeb yog yuav tsum tau los ntawm cov neeg mob uas muaj kev pheej hmoo nrog cov zaub mov tsis muaj calorie, ua haujlwm tsis txaus lub cev, endocrine pathologies (adrenal thiab pituitary tsis txaus, hypothyroidism, tshem tawm corticosteroids tom qab siv sijhawm ntev lossis siv tshuaj ntau, CVD hnyav ntawm kev mob atherosclerosis lossis mob hlab plawv). Qhov kev mob ntshav qab zib no yog yam tsawg kawg nkaus uas yog kho tus mob ntshav qab zib MV - 30 mg.
Txhawm rau kom tau txais 100% qhov tshwm sim, qhov koob tshuaj tuaj yeem nce ntxiv rau 120 mg / hnub. Ib qho yuav tsum tau ua ua ntej yog kev hloov kho lub neej - hloov mus rau kev noj zaub mov kom tsawg, ua kom lub cev qoj ib ce, thiab tswj lub xeev kev xav.
Yog tias tsim nyog, koj tuaj yeem ntxiv tshuaj kho mob nrog Diabeton MV metformin, insulin, thiazolidinediones. Hauv qhov no, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov muaj cov kev mob tshwm sim hauv txhua qhov tshuaj thiab lawv sib cuam tshuam. Ua ntej tshaj plaws, peb tab tom tham txog kev pheej hmoo ntawm lub qog ntshav qab zib.
Pab nrog overdose
Qhov phom sij tseem ceeb ntawm kev siv ntau tshaj yog qhov mob hypoglycemic. Nrog rau cov tsos mob me thiab muaj kev tswj hwm tus kheej, nws yog qhov tsim nyog los txo cov qog ntawm Diabeton MV thiab lwm yam tshuaj tiv thaiv kab mob, kho cov khoom noj kom tau cov ntsiab lus tsis zoo. Saib xyuas kev noj qab haus huv ntawm tus mob ntshav qab zib yog qhov tseem ceeb kom txog thaum tus mob glycemia tiav kiag li, vim kev rov huam mob dua nyob hauv cov xwm txheej no.
Yog tias pom cov tsos mob glycemic muaj tseeb tshaj thiab qhia tseeb kev hem thawj rau kev noj qab haus huv, tshwj xeeb yog tus neeg raug mob tsis nco qab, nyob hauv txoj kev tsis nco qab, nrog rau mob nriaj caj dab, yuav tsum tau kho mob sai, tom qab mus pw hauv tsev kho mob. Thaum pib lub sijhawm zoo tshaj plaws, cov ntshav qab zib yuav tsum tau txhaj tshuaj rau cov ntshav nrog 50 ml ntawm cov piam thaj.
Txhawm rau kom muaj kev sib npaug (saum toj 1 g / l) - kuj muaj 10% kev daws teeb meem. Kev soj ntsuam ntawm txhua qhov ntsuas tseem ceeb tau ua nrog tsawg kawg 48 teev. Txij li thaum gliclazide nquag khi rau cov ntshav protein, hemodialysis nyob rau hauv rooj plaub no ua tsis tau dab tsi.
Kuv yuav hloov li cas hloov ntshav qab zib MV
Tus thawj MV Diabeton, uas yog tsim los ntawm Fabkis lub tuam txhab Servier, muaj txaus pheej yig analogues raws li gliclazide, tab sis cov kev mob tshwm sim ntawm cov tshuaj no tuaj yeem hais tawm ntau dua, yog li thaum xaiv koj yuav tsum tsom tsis zoo rau tus nqi, tab sis kuj pom zoo cov lus pom zoo ntawm tus kws kho mob tuaj koom.
Cov tsev muag tshuaj tuaj yeem muab cov tshuaj generics rau koj:
- RDiabefarm, Glyclazide, Glucostabil, Glidiab;
- Czech Gliklad;
- Yugoslavian Predian thiab Glioral;
- Indian Diabinax, Diatik, Reklid, Glisid.
Yog tias gliclazide-based khoom lag luam tsis haum, tus endocrinologist yuav xaiv:
- Cov tshuaj ntawm sulfonylurea series raws li glibenclamide, glycvidone, glimepiride;
- Cov tshuaj ntawm cov chav kawm sib txawv, tab sis nrog tib lub tshuab ntawm kev txiav txim siab, piv txwv li NovoNorm los ntawm cov chav kawm av nplaum;
- Cov tshuaj uas muaj cov txiaj ntsig zoo ib yam li Januvia lossis Galvus (DPP-4 inhibitors).
Glidiab MV lossis Diabeton MV: dab tsi yog qhov zoo tshaj plaws rau qee tus neeg mob tsuas yog txiav txim los ntawm tus kws kho mob. Cov ntaub ntawv yog muab rau kev hais dav dav, thiab tsis yog rau kev tshuaj xyuas tus kheej thiab kev tswj hwm tus kheej ntawm cov tshuaj muaj mob loj.
Dab Tsi Mob Ntshav Qab Zib MV Cov Ntshav Qab Zib Xav Txog
Txog Tus Mob Ntshav Qab Zib MV, kev txheeb xyuas cov neeg mob ntshav qab zib yog qhov tsis txaus siab: qab zib pab tswj hwm, tab sis ob peb tus neeg tswj hwm kom tsis txhob muaj qhov tsis txaus siab xav tau. Qhov kev ntshai tshaj plaws yog qhov tseeb hais tias tom qab cov tshuaj zoo li no, yuav luag txhua qhov hloov mus rau cov tshuaj insulin - qee qhov ua ntej, qee zaum tom qab.
Tus mob ntshav qab zib MV endocrinologist tsis yog kws kho mob rau txhua tus neeg mob ntshav qab zib, tab sis txawm tias cov neeg uas haum rau cov tshuaj yuav tshwm sim quav tshuaj. Vim tias kev noj tshuaj tsis tsim nyog lossis tsis ua raws li lub sijhawm tswj hwm, qhov ua tau ntawm cov tshuaj yuav tsis raug rau cov lus tshaj tawm.
Nrog rau qhov ua kom mob ntshav qab zib ntau dhau, txawm tias muaj zaub mov noj kom tsawg thiab ua kom ib ce muaj zog, yuav tsum tau siv lwm txoj hauv kev kho kom zoo. Muaj ntau ntau yam nuances, yog tias koj tau tso npe Diabeton MV, kawm qhov kev qhia yooj yim no kom ntseeg tau tias kev teem caij tau kho kom raug.
Cov ntaub ntawv ntxiv txog Ntshav Qab Zib MV - hauv video:
