Tam sim no qhov kev xaiv ntawm txhais tau tias los ntawm cov ntshav qab zib tuaj yeem tsim kho tau yog qhov dav heev: ntawm no yog kev tshuaj ntsuam genetic engineering thiab ntau yam tshiab tam sim no analog insulins. Rinsulin tsuas yog cov tshuaj yaj yeeb hauv tsev uas tau tswj hwm los noj ib qho tseem ceeb (ntau dua 10%) ntawm cov tshuaj insulin lag luam hauv tebchaws Russia.
Kev nthuav dav ntawm cov khoom tsim thiab qub thev naus laus zis, kev tsim tawm huab hwm coj txij li xyoo 2004, tau ua los ntawm Geropharm. Rinsulin muaj nyob rau hauv 2 daim ntawv - Rinsulin P lub ntsej muag luv luv thiab Rinsulin NPH, thiab insulin lyspro thiab glargine tab tom kuaj mob. Qhov zoo ntawm cov khoom yog paub tseeb los ntawm ntau lub chaw soj ntsuam European txoj kev ywj pheej. Raws li lawv, cov hauj lwm zoo ntawm peb cov tshuaj tsis muaj qhov phem dua li txawv teb cov yeeb yaj kiab uas muaj cov khoom qub.
Rinsulin P - kev piav qhia thiab cov foos tso tawm
Hauv qab no yog qee cov ntaub ntawv hais txog cov tshuaj uas yuav muab cov duab ntawm cov tshuaj insulin.
Mob ntshav qab zib thiab siab surges yuav yog ib yam dhau los
- Li qub ntawm qab zib -95%
- Kev tshem tawm ntawm cov hlab ntsha thrombosis - 70%
- Ntaus tau ntawm lub plawv dhia muaj zog -90%
- Kev tshem tawm ntshav siab - 92%
- Qhov nce hauv lub zog nruab hnub, txhim kho pw tsaug zog thaum hmo ntuj -97%
Nkaus
Rinsulin P yog nqus sai rau hauv cov ntshav los ntawm cov nqaij mos subcutaneous, cov nyhuv hypoglycemic pib tom qab ib nrab ib teev. Cov tshuaj hormones khi rau cov cell receptors, uas tso cai thauj cov piam thaj ntawm cov ntshav mus rau cov ntaub so ntswg. Rinsulin lub peev xwm los ua kom cov glycogen tsim kho thiab txo qis ntawm cov piam thaj ua ke hauv lub siab tseem ua rau glycemia txo qis.
Cov nyhuv ntawm cov tshuaj nyob ntawm tus nqi ntawm nqus, thiab hais tias, nyob rau hauv, nyob rau lub tuab thiab cov ntshav ntawm subcutaneous ntaub so ntswg ntawm qhov chaw txhaj tshuaj. Hauv nruab nrab, cov chaw muag tshuaj ntawm Rinsulin P zoo ib yam li lwm cov insulins luv luv:
- lub sijhawm pib yog 30 feeb
- ncov - txog 2 teev
- cov yeeb yam tseem ceeb yog 5 teev,
- tag nrho lub sijhawm ua haujlwm - txog 8 teev.
Koj tuaj yeem kho qhov kev ua tiav ntawm insulin los ntawm kev txhaj tshuaj rau hauv plab lossis sab caj npab, thiab maj mam txo los ntawm kev txhaj nws rau hauv pem hauv ntej ncej puab.
Txhawm rau them nyiaj mob ntshav qab zib mellitus ntawm Rinsulin, tus neeg mob yuav tsum ua raws li 6 pluas noj nyob rau ib hnub, kev ncua sij hawm nruab nrab ntawm 3 pluas noj yuav tsum yog 5 teev, nyob nruab nrab ntawm lawv cov khoom noj txom ncauj ntawm 10-20 g ntawm qeeb carbohydrates yog qhov yuav tsum tau.
Muaj pes tsawg leeg
Rinsulin P tsuas muaj ib qho ua kom nquag plias - tib neeg lub cev insulin. Nws yog tsim los ntawm txoj kev xav tau, uas yog, siv cov kab mob hloov pauv txhob kaw. Feem ntau E. coli lossis poov xab yog siv rau cov laj thawj no. Hauv cov qauv thiab cov qauv, cov insulin no tsis txawv ntawm cov tshuaj hormones uas cov txiav ua kua hluavtaws.
Muaj tsawg tsawg ntu pabcuam nyob rau hauv Rinsulin P dua li hauv cov analogues txawv teb. Ntxiv nrog rau cov tshuaj insulin, nws tsuas muaj dej, cov tshuaj tiv thaiv metacresol thiab stabilizer glycerol. Ntawm ib sab, vim qhov no, qhov yuav ua rau muaj kev tsis haum ntawm qhov chaw txhaj tshuaj yog tsawg dua. Ntawm qhov tod tes, kev nqus mus rau hauv cov ntshav thiab cov ntshav qab zib-txo cov txiaj ntsig ntawm Rinsulin tej zaum yuav txawv dua. Yog li, hloov mus rau lwm cov tshuaj nrog tib cov tshuaj muaj zog yuav siv ntau hnub, thaum lub sijhawm them nyiaj ntawm ntshav qab zib mellitus zuj zus.
Tso Tawm Cov Ntawv
Rinsulin P yog cov xim tsis muaj kob, ua kom pom pob tshab, hauv ib milliliter ntawm 100 units ntawm cov tshuaj hormones.
Cov Ntawv Tso Tawm:
- Vials nrog tov ntawm 10 ml, ib cov tshuaj los ntawm lawv yuav tsum tau txhaj nrog koob tshuaj insulin.
- 3 ml cartridges. Lawv tuaj yeem tso rau hauv txhua lub koob txhaj tshuaj uas tsim los rau tus qauv cartridge: HumaPen, BiomaticPen, Autopen Classic. Txhawm rau kom muaj peev xwm nkag mus rau qhov tseeb ntau npaum li cas ntawm cov tshuaj insulin, kev nyiam yuav tsum tau muab rau cov kua koob txhaj tshuaj nrog qhov kev siv tshuaj tsawg kawg. Piv txwv li, HumaPen Luxura pub koj kom tau 0,5 units.
- Cov tshuaj phwj uas siv tag pov tseg Rinastra 3 ml. Hloov daim laub rau hauv lawv tsis tuaj yeem ua, kauj ruam 1 chav.
Cov lus qhia rau kev siv Rinsulin
| Cov Khoom Qhia | Ib yam ntshav qab zib insulin-yam mob ntshav qab zib. Cov ntshav qab zib tsis-insulin-mob ntshav qab zib thaum lub sijhawm hypoglycemic cov neeg sawv cev tsis muaj txiaj ntsig lossis raug txwv: ketoacidosis thiab lwm yam mob hyperglycemic, kev phais mob, cev xeeb tub. Yuav tsis siv cov tshuaj Rinsulin tso rau hauv cov tshuaj insulin. |
| Cov Yuav Tsum Muaj | Cov tib neeg ua xua rau insulin lossis ntu sib xyaw ntawm cov tshuaj. Qhov tshuaj insulin tsis tso cai thaum qab zib qis dua qhov qub. |
| Tus thawj coj kev tswj hwm | Lub sijhawm ntawm kev ua nyob rau hauv cov lus qhia rau kev siv yog xam nrog qhov xwm txheej ntawm kev tswj hwm subcutaneous. Hauv cov chaw kho mob, tso ntshav siab thiab txhaj tshuaj rau ntshav yog tso cai. >> Yuav ua li cas muab cov tshuaj insulin tsis mob |
| Tsuas tshuaj | Nws yog xaiv rau cov ntshav qab zib txhua tus zuj zus, nyob ntawm tus yam ntxwv ntawm cov khoom noj khoom haus, qhov hnyav ntawm tus kab mob, qhov hnyav ntawm tus neeg mob, nws qhov rhiab rau insulin. Qhov kev txhaj tshuaj txhua hnub ntawm Rinsulin yog thaj tsam li 0.5-1 units ntawm cov tshuaj hormones hauv ib kg. |
| Tus naj npawb ntawm kev txhaj tshuaj | Txoj kev kho mob: Rinsulin R - peb zaug hauv ib hnub, 30 feeb ua ntej noj zaub mov tseem ceeb, Rinsulin NPH - ob zaug, ua ntej noj tshais thiab ua ntej yuav mus pw. |
| Taw qhia cov kev cai | Qhov ntev ntawm lub koob yog xaiv nyob ntawm qhov tuab ntawm cov subcutaneous rog. Qhov me dua nws, cov koob yuav tsum luv dua. Kev daws yog muab maj mam, ua raws cov txheej txheem txhaj tshuaj. Txhawm rau kom tsis txhob lipodystrophy, cov tshuaj siv ntawm chav sov, txhua zaus siv rab koob tshiab thiab thaj chaw txhaj tshuaj hloov pauv. |
| Cia | Rinsulin xav tau tshwj xeeb cia khoom: ntawm 2-8 ° C nws tseem siv tau rau 2 xyoos, ntawm 15-25 ° C - 4 lub lis piam. Cov cim ntawm kev lwj yog suav nrog clouding, plaub ya ri lossis muaju hauv sab hauv lub taub ntim khoom. Cov tshuaj uas ploj mus tsis tuaj yeem ua rau pom qhov txawv hauv lub ntsej muag, yog li ntawd, nrog kev ntseeg tsis txaus ntseeg me me, qhov zoo ntawm Rinsulin lub raj mis yuav tsum tau hloov nrog lub tshiab. Cov tshuaj insulin yog rhuav tshem los ntawm ultraviolet hluav taws xob, yog li ntawd cov fwj tau khaws cia hauv cov thawv ntawv, thiab cov xaum xaum xev kaw nrog lub hau tom qab siv txhua zaus. >> Yuav muab cov tshuaj insulin li cas |
Muaj peev xwm tsis pom tshwm sim ntau
Ntau zaus cov kev mob tshwm sim ntawm Rinsulin yog qhov tsawg, feem ntau cov neeg mob tsuas yog ntsib tus mob hypoglycemia me me xwb.
Cov npe ntawm cov tsis tuaj yeem tsis nyiam raws li cov lus qhia:
- Kev mob ntshav qab zib tsawg yog ua tau yog tias qhov ntau ntawm cov tshuaj tau muab xam tsis raug thiab dhau ntawm qhov kev xav ntawm lub zog xav tau. Kev tsis ua raws li cov lus qhia rau kev siv kuj tuaj yeem ua rau poob qab zib: cov txheej txheem kev txhaj tshuaj tsis raug cai (insulin nkag mus rau hauv cov leeg), cua sov ntawm qhov chaw txhaj tshuaj (huab cua sov, nrawm, txhuam), ua tsis raug lub ntsej muag, ua haujlwm lub cev tsis muaj feem. Kev mob ntshav siab ntshav qis yuav tsum raug tshem tawm thaum nws thawj cov tsos mob tshwm sim: malaise, tshee, tshaib plab, mob taub hau. Feem ntau 10-15 g ntawm carbohydrates ceev yog qhov txaus rau qhov no: qab zib, kua txiv, qabzib ntsiav tshuaj. Kev mob ntshav khov ntau heev tuaj yeem ua rau tsis muaj dab tsi ua rau lub paj hlwb puas tsuaj, ua rau tsis nco qab lawm.
- Qhov thib ob feem ntau cov kev mob tshwm sim yog kev fab tshuaj tsis haum. Feem ntau cov feem ntau, lawv tau hais tawm rau pob khaus lossis liab ntawm thaj chaw txhaj tshuaj thiab ploj mus li ob peb lub lis piam tom qab kev teem sijhawm kho tshuaj insulin. Yog tias khaus khaus, los tiv thaiv cov tshuaj antihistamines. Yog tias kev ua xua tau hloov mus rau hauv ib qho qauv dav dav, urticaria lossis Quincke's edema tau tshwm sim, Rinsulin R yuav tsum tau hloov.
- Yog tias cov ntshav qab zib tau muaj hyperglycemia ntev ntev, kev txhaj tshuaj insulin thawj zaug yog xam thiaj li ua rau cov ntshav qab zib qis kom zoo, dhau ib hlis. Nrog lub ntsej muag poob hauv qabzib mus rau ib txwm, qhov tsis zoo ib ntus hauv kev nyob zoo yog tau: qhov muag plooj, o, hnov mob ntawm nqaj - yuav ua li cas los suav cov koob tshuaj insulin.
Ntau yam tshuaj cuam tshuam rau kev ua haujlwm ntawm cov tshuaj insulin, yog li cov neeg mob ntshav qab zib ntawm kev siv tshuaj insulin yuav tsum koom tes nrog kws kho mob txhua yam tshuaj, tshuaj ntsuab thiab kev noj haus uas lawv npaj yuav siv.
Cov kev qhia tswv yim kom them nyiaj tshwj xeeb rau cov pawg tshuaj nram no:
- Cov tshuaj hormones: tiv thaiv kev ua kom tsis txhob, qog cov thyroid, glucocorticosteroids;
- tshuaj kho tus mob ntshav siab: tshuaj kho tus mob thiazide pawg, txhua yam tshuaj uas xaus-ntawm tus mob thiab-theem, lazartan;
- vitamin B3;
- lithium npaj;
- tetracyclines;
- txhua cov kab mob hypoglycemic;
- acetylsalicylic acid;
- qee cov tshuaj tiv thaiv kev nyuaj siab.
Kev tiv thaiv kab mob ntshav qab zib mellitus zuj zus thiab txhua yam tshuaj thiab dej haus uas muaj cawv yuav ua rau muaj ntshav nce siab tsawg kawg - saib dab tsi ua kom ntshav qab zib ua rau. Cov tshuaj beta-blocker siv rau cov kab mob plawv txo cov tsos mob ntawm cov ntshav qab zib hauv lub cev thiab tiv thaiv nws los ntawm kev kuaj pom ntawm lub sijhawm.
Daim ntawv thov nta
Tom qab qhov kawg ntawm kev nqis tes ua, insulin raug rhuav tshem hauv daim siab thiab lub raum. Yog tias tus mob ntshav qab zib muaj kab mob ntawm ib qho ntawm cov plab hnyuv siab raum no, kev noj cov tshuaj Rinsulin tuaj yeem xav kho. Kev xav tau ntxiv rau insulin yog pom nyob rau lub sijhawm cov kev hloov hauv hormonal, nrog cov kabmob kis, kub ib ce, raug mob, ntxhov siab, nkees nkees. Cov koob tshuaj ntawm cov tshuaj yuav tsis muaj tseeb yog tias tus neeg mob ntshav qab zib muaj qhov ntuav, raws plab, thiab mob hauv cov zom zaub mov.
Cov tshuaj yeeb yaj kiab uas nrov tshaj plaws ntawm Rinsulin R yog Danish Actrapid thiab American Humulin Tsis tu ncua. Cov ntaub ntawv tshawb fawb qhia tias Rinsulin cov cim ntsuas tau zoo yog nyob rau theem ntawm European cov qauv.
Kev xyuas ntshav qab zib tsis yog qhov zooCov. Ntau tus, thaum hloov los ntawm cov tshuaj yeeb yaj kiab mus rau ib qho kev siv hauv tsev, nco ntsoov qhov xav tau hloov pauv ntawm cov tshuaj, dhia hauv qab zib thiab qhov siab kawg ntawm kev ua. Muaj kev soj ntsuam zoo dua ntawm cov tshuaj yaug yaug ntawm cov neeg mob uas siv tshuaj insulin thawj zaug. Lawv tswj kom tau txais txiaj ntsig zoo rau cov ntshav qab zib thiab zam kom tsis txhob mob ntshav qab zib siab ntau.
Yog tias muaj qhov ua xua tawm tsis tau, Rinsulin yuav tsum raug muab pov tseg. Feem ntau, lwm tus neeg cov insulins ua rau tib cov tshuaj tiv thaiv, yog li lawv siv ultrashort txhais tau tias - Humalog lossis NovoRapid.
Tus nqi ntawm Rinsulin P - los ntawm 400 rubles. ib lam fwj kom txog 1150 rau 5 xaum xaum.
Qhov sib txawv ntawm Rinsulin P thiab NPH
Rinsulin NPH yog cov tshuaj nruab nrab ntawm tib lub chaw tsim khoom. Raws li cov lus qhia, nws yog siv los ua kom muaj suab thaj sai. Rinsulin NPH muaj tib lub hauv paus ntsiab lus ntawm kev nqis tes ua, tso tawm daim ntawv, cov cim zoo sib xws, contraindications thiab phiv raws li Rinsulin R. Raws li txoj cai, nrog kev kho tshuaj insulin ob hom tshuaj insulin ua ke - luv thiab nruab nrab. Yog tias qhov zais ntshis ntawm koj tus kheej cov tshuaj hormones yog qee khaws cia (hom 2 thiab cov ntshav qab zib hauv poj niam), koj tsuas siv tau ib cov tshuaj.
Cov Nta ntawm Rinsulin NPH:
| Lub sijhawm ua | Pib yog 1.5 teev, lub ncov yog 4-12 teev, sijhawm ntev txog 24 teev, nyob ntawm seb ntau npaum li cas. |
| Muaj pes tsawg leeg | Ntxiv rau tib neeg cov tshuaj insulin, cov tshuaj muaj protamine sulfate. Qhov sib xyaw ua ke no hu ua insulin-isophan. Nws tso cai rau koj kom maj mam nqus cov tshuaj hormone thiab lengthens nws lub sijhawm. |
| Cov tsos ntawm cov tshuaj | Rinsulin NPH muaj ib qho kev xaj nyob hauv qab, yog li nws yuav tsum sib xyaw ua ntej kev tswj hwm: yob lub pob hauv nruab nrab ntawm xib teg thiab tig nws ntau zaus. Cov tshuaj tiav tau hloov los ua xim dawb xim yam tsis suav nrog. Yog tias cov nag lossis daus tsis yaj, cov ntshav nyob hauv lub taub hau, cov kua dej yuav tsum tau hloov nrog dej tshiab. |
| Tus thawj coj kev tswj hwm | Tsuas yog subcutaneously. Nws tsis tuaj yeem siv los tshem tawm hyperglycemia. |
Tus nqi ntawm ib lub raj mis ntawm Rinsulin NPH ~ 400 rubles., Tsib daim cartridges ~ 1000 rubles., Tsib tsib xaum xaum ~ 1200 rubles.
