Cov ntsiav tshuaj ntshav qab zib feem ntau pab tshem cov piam thaj hauv cov ntshav ntawm cov ntshav qab zib. Acarbose, chav kawm ntawm α-glucosidase inhibitors, ua haujlwm ntawm theem ntxov. Nws txwv tsis pub lub zom zom ntawm cov carbohydrates kom nkag mus rau txoj hnyuv nrog zaub mov, yog li ua rau maj mam nkag mus ntawm cov piam thaj hauv cov ntshav.
Acarbose tsuas yog ua haujlwm hauv zos, nws tsis cuam tshuam rau kev tsim tshuaj ntawm cov kua dej thiab lub siab ua haujlwm, tsis pab txhawb rau hypoglycemia. Hmoov tsis zoo, cov tshuaj no tsis nyab xeeb li nws yuav zoo li. Vim tias qhov tsis txaus ntshai tshwm sim nyob rau hauv cov lus qhia, acarbose raug suav hais tias yog ib qho tshuaj tiv thaiv. Nws yog kho txawm nrog qhov tsis muaj txiaj ntsig ntawm lwm yam tshuaj, lossis nrog yuam kev ntau ntawm cov zaub mov noj.
Acarbose yog dab tsi thiab nws ua haujlwm li cas
Cov khoom noj carbohydrates hauv peb cov zaub mov yog rau qhov feem cuam tshuam. Ib zaug hauv cov zom zaub mov, lawv raug hydrolyzed los ntawm cov enzymes tshwj xeeb - glycosidases, tom qab uas lawv decompose rau monosaccharides. Cov suab thaj yooj yim, nyeg, nkag rau hauv plab hnyuv thiab nkag mus rau cov ntshav.
Acarbose hauv nws cov qauv yog pseudosaccharide tau los ntawm cov txheej txheem biotechnological. Nws sib tw nrog cov suab thaj los ntawm cov zaub mov hauv cov hnyuv: nws khi rau cov enzymes, ib ntus tsis pub lawv ntawm lub peev xwm los zom cov carbohydrates. Vim qhov no, acarbose ua rau kom khiav ntawm cov piam thaj mus rau hauv cov ntshav. Qhov qeeb qeeb thiab muaj pes tsawg dua uniformly qabzib txeem mus rau hauv cov hlab, siv tau ntau yog muab tshem tawm los ntawm lawv mus rau hauv cov ntaub so ntswg. Glycemia ua qis dua, nws hloov zuj zus tom qab noj mov tsawg.
Pov thawj Acarbose nyhuv:
Mob ntshav qab zib thiab siab surges yuav yog ib yam dhau los
- Li qub ntawm qab zib -95%
- Kev tshem tawm ntawm cov hlab ntsha thrombosis - 70%
- Ntaus tau ntawm lub plawv dhia muaj zog -90%
- Kev tshem tawm ntshav siab - 92%
- Qhov nce hauv lub zog nruab hnub, txhim kho pw tsaug zog thaum hmo ntuj -97%
- Normalizes glycated hemoglobin, txhim kho kev them nyiaj mob ntshav qab zib.
- Nrog rau kev ua txhaum ntawm cov piam thaj hauv kev siab ntev txog 25% txo cov kev pheej hmoo ntawm kev tsim muaj ntshav qab zib.
- Tiv thaiv kab mob plawv: txoj kev pheej hmoo yog txo qis 24% hauv cov neeg mob ntshav qab zib, los ntawm 49% hauv cov neeg mob NTG.
Acarbose zoo dua rau cov neeg mob uas muaj kev yoo mov glycemia thiab txhawb zog tom qab noj mov. Cov kev tshawb fawb pom tias nws siv tau tuaj yeem txo cov ntshav qabzib 10%, qabzib tom qab noj mov 25%, glycated hemoglobin los ntawm 21%, roj cholesterol los ntawm 10%, triglycerides los ntawm 13%. Nrog rau cov tshuaj glycemia, cov concentration ntawm cov tshuaj insulin hauv cov ntshav txo qis. Vim tias cov ntsiab lus qis dua ntawm insulin thiab lipids hauv cov neeg mob ntshav qab zib, insulin tsis kam thiab qhov kev pheej hmoo ntawm atherosclerosis tsawg dua, poob phaus yog yooj yim.
Acarbose tau siv los ua hypoglycemic rau ntau tshaj 20 xyoo. Hauv tebchaws Russia, tsuas yog ib cov tshuaj nrog cov tshuaj no tau sau npe - Glucobai los ntawm lub tuam txhab German Bayer Pharma. Cov ntsiav tshuaj muaj 2 pes tshuaj - 50 thiab 100 mg.
Kev qhia rau kev siv tshuaj
Mob ntshav qab zib, acarbose tuaj yeem kho:
- Yog hais tias tus kab mob yog mob sib khuav xwb, tab sis kev noj haus tsis yog ib txwm ua raws, lossis nws tsis txaus los ua kom qab zib.
- Ntxiv nrog rau Metformin, yog tias koj tus kheej cov insulin tsim tawm hauv cov khoom tsim nyog.
- Yog hais tias kev noj zaub mov muab glycemia li qub, tab sis ib qho dhau ntawm triglycerides raug kuaj hauv cov ntshav.
- Cov neeg mob uas muaj lub cev nyhav dhau los es tsis txhob siv sulfonylurea derivatives, vim lawv feem ntau ua rau mob ntshav qab zib.
- Nrog rau cov tshuaj insulin, yog tias nws tsis pab tau kom tshem ntawm cov piam thaj sai sai tom qab noj mov.
- Txo qhov koob tshuaj ntawm luv luv insulin.
Glucobai tseem siv tau rau qhov poob phaus, txawm tias qhov tseeb ntawm cov lus qhia rau kev siv tsis cuam tshuam txog qhov tshwm sim ntawm cov tshuaj.
Cov tshuaj tsis tuaj yeem noj nyob hauv cov rooj plaub no:
| Pom kev sib deev | Vim li cas rau qhov txiav npluav |
| Cov me nyuam muaj hnub nyoog | Cov kev tshawb fawb txog kev nyab xeeb ntawm acarbose hauv cov pab pawg ntawm cov neeg mob no tsis tau ua. |
| Cev xeeb tub, GV | |
| Mob plab zom mov cov kab mob, nrog rau cov neeg sab nraum theem ntawm exacerbation. | Cov tshuaj ua haujlwm hauv cov hnyuv, yog li teeb meem nrog kev zom lossis kev nqus ntawm cov as-ham ncaj qha cuam tshuam nws cov nyhuv. |
| Cov kab mob nrog cov roj ntau ntxiv hauv cov hnyuv. | Carbohydrate cia nyob rau hauv txoj hnyuv txo cov kev mob tsis zoo. |
| Tsis ua haujlwm lawm yog GFR <25. | Ib feem peb ntawm acarbose yog tawm ntawm lub raum, yog li lawv yuav tsum tsawg kawg ib nrab ua tiav lawv cov haujlwm. |
Cov lus qhia rau kev siv
Yuav pib noj cov ntshav qab zib hauv ntshav qab zib:
- Qhov tshuaj thawj zaug yog 150 mg rau hauv 3 koob. Nws yog qhov tsim nyog uas acarbose nkag mus rau txoj hlab pas tib lub sijhawm nrog thawj carbohydrates, yog li cov ntsiav tshuaj yuav tsum haus cawv ua ntej noj mov.
- Yog tias qhov nyiaj no tsis txaus rau kev zom zaws glycemia, qhov muab tshuaj yog ob npaug. Txhawm rau kom txo qhov hnyav ntawm cov kev mob tshwm sim, koj yuav tsum muab lub cev 1-2 lub hlis kom dhau los siv tshuaj, thiab tsuas yog tom qab ntawd nce thawj zaug koob tshuaj.
- Cov koob tshuaj zoo tshaj plaws yog 300 mg, faib ua 3 zaug. Rau cov neeg mob uas tsis muaj peev xwm saib xyuas qabzib, lub koob tshuaj no yog qhov tso cai ntau tshaj plaws.
- Qhov ntau kawg rau noj yog 600 mg. Nws yog tshuaj nyob hauv qhov tshwj xeeb, thiab tsuas yog tus mob ntshav qab zib tsis muaj kev mob tshwm sim.
Qhov tshwm sim thaum siv Acarbose
| Qhov tshwm sim ntau zaus,% | Qhov kev txiav txim tsis tsim nyog raws li cov lus qhia |
| >10 | Flatulence, tuaj yeem nrog los ntawm tsam plab, muaj roj ntau dua. Kev siv zog ntawm cov roj tsim muaj ntau ntxiv nrog kev nce siab ntawm acarbose thiab cov nyiaj ntawm carbohydrates nyob rau hauv cov zaub mov noj. |
| <10 | Mob plab, mob plab zom mov ua txhaum kev noj haus. |
| <1 | Ntxiv kev ua haujlwm ntawm daim siab enzymes. Qhov kev ua txhaum no tuaj yeem ploj ntawm nws tus kheej, yog li koj yuav tsum tsis txhob cuam tshuam kev kho mob tam sim ntawd, thaum xub thawj nws txaus los tswj lub siab ua haujlwm. |
| <0,1 | Kev o, xeev siab, ntuav, mob hauv plab. |
| raug rho tawm tus neeg mob | Hloov ntshav muaj pes tsawg leeg, platelet tsis txaus, zawv plab hnyuv, kab mob siab. Kev fab rau cov Cheebtsam hauv ncoo. |
Nrog kev siv tshuaj ntau dhau ntawm acarbose, qhov hnyav ntawm cov mob tshwm sim hauv cov hnyuv nce zuj zus, raws plab yuav luag tas li. Txhawm rau zam kom tsis xis nyob, tom ntej 6 teev noj tsuas yog carbohydrate tsis muaj zaub mov thiab dej qab zib. Lub sijhawm no, cov tshuaj feem ntau tswj kom tawm ntawm lub cev.
Siv Acarbose Glucobai rau qhov poob phaus
Thaum noj acarbose, qee cov carbohydrates tsis muaj sijhawm rhuav tshem thiab raug tawm ntawm lub cev nrog quav, thiab cov calories kom tsawg yog txo kom haum. Lawv tau sim siv cov cuab yeej no ntau dua ib zaug rau kev poob phaus, txawm tias kev tshawb fawb tau ua los ntawm kev ua haujlwm ntawm cov tshuaj rau qhov poob phaus. Hauv cov neeg mob uas muaj ntshav qab zib, qhov qhia txog ntawm acarbose rau hauv kev kho tus mob ua rau muaj qhov hnyav nruab nrab ntawm kev poob phaus ntawm 0.4 kg. Nyob rau tib lub sijhawm, caloric kom tsawg thiab siv ntawm cov khoom seem yuav nyob zoo li qub.
Nws kuj tau pom tias kev siv Acarbose rau kev poob phaus yog qhov zoo tshaj plaws ua ke nrog kev noj haus thiab kis las. Lub sijhawm no, txoj kev kawm tau tshawb nrhiav hauv cov neeg noj qab haus huv. Cov txiaj ntsig tau txhawb nqa: dhau 5 lub hlis, cov neeg mob txo lawv BMI los ntawm 2.3, hauv pawg tswj hwm tsis muaj acarbose - tsuas yog 0.7. Cov kws kho mob tawm tswv yim tias cov nyhuv no cuam tshuam nrog kev phiv tshuaj. Sai li lawv poob phaus nrog carbohydrates, lawv sai sai ua rau cov txheej txheem ntawm cov fermentation hauv cov hnyuv, flatulence lossis raws plab pib. Acarbose ntawm no ua raws li hom kev taw qhia ntawm kev noj zaub mov kom raug, txhua qhov kev ua txhaum ntawm kev noj zaub mov noj tsis zoo nrog qhov tsis zoo.
Dab tsi tuaj yeem hloov tau
Glucobai tsis muaj tiav analogues. Ntxiv rau acarbose, ib pawg ntawm α-glucosidase inhibitors suav nrog cov tshuaj nquag ua voglibose thiab miglitol. Raws li lawv, German Diastabol, Turkish Alumina, Ukrainian Voksid tau tsim. Lawv muaj tib lub txiaj ntsig, yog li ntawd lawv tuaj yeem raug suav hais tias yog analogues. Hauv cov chaw muag tshuaj ntawm Russia, tsis muaj ib yam ntawm cov tshuaj no, yog li cov neeg mob ntshav qab zib hauv tsev yuav tsum tau muab lawv tus kheej mus rau Glucobai lossis nqa cov tshuaj los ntawm txawv teb chaws.
Nqi
Acarbose tsis muaj nyob hauv cov npe tseem ceeb thiab Cov Tshuaj Tseem Ceeb, yog li cov neeg mob ntshav qab zib tau raug yuam kom yuav Glucobay lawv tus kheej. Tus nqi nyob rau hauv Russia yog li ntawm 500 txog 590 rubles. rau 30 ntsiav tshuaj ntawm 50 mg. Kev noj tshuaj ntawm 100 mg yog me ntsis kim dua: 650-830 rubles. rau tus nqi ib yam.
Qhov nruab nrab, kev kho mob yuav raug nqi 2200 rubles. rau ib hlis. Hauv cov khw muag tshuaj online, cov tshuaj yog me ntsis pheej yig dua, tab sis nyob rau hauv feem ntau ntawm lawv koj yuav tsum tau them rau kev xa khoom.
Kev Ntsuam Xyuas Rau Neeg Mob
Raws li cov neeg mob ntshav qab zib, Glucobai yog ib hom tshuaj "tsis kaj siab". Cov neeg mob tau yuam kom tsis tsuas yog ua raws li cov zaub mov tsis zoo, tab sis qee kis kom tso cov khoom noj siv mis, vim tias lactose kuj tseem tuaj yeem ua rau muaj teeb meem plab zom mov. Cov suab thaj-txo cov txiaj ntsig ntawm acarbose raug tshuaj xyuas zoo. Cov tshuaj ua tiav qhov ua tau zoo ntawm qabzib tom qab noj mov, txo nws cov kev hloov pauv thaum nruab hnub.
Kev txheeb xyuas qhov kev poob phaus tsis muaj qhov zoo. Lawv haus tshuaj feem ntau yog cov hniav qab zib, uas tsis tuaj yeem ua yam tsis muaj khoom noj qab zib ntev. Lawv pom cov tshuaj no tsis muaj dab tsi, tab sis kim heev. Ntxiv rau, vim muaj kev phiv, cov zaub mov carbohydrate tsuas tuaj yeem noj hauv tsev, tsis ntshai yam tshwm sim. Piv nrog Xenical, Glucobay zoo dua taus, tab sis cov nyhuv ntawm nws tsawg dua.
