Rosinsulin: tshuaj xyuas ntawm kev siv cov tshuaj insulin, cov lus qhia

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Rosinsulin C yog muab tshuaj subcutaneously 1-2 zaug hauv ib hnub, txog ib nrab ib teev ua ntej noj mov. Txhua zaus, qhov chaw txhaj tshuaj yuav tsum tau hloov.

Hauv qee kis, tus kws endocrinologist tuaj yeem sau ntawv rau tus neeg mob txhaj tshuaj ntawm cov tshuaj.

  • nrog ntshav qab zib mellitus yam 1 thiab 2;
  • nyob rau theem ntawm kev ua haujlwm rau kev tiv thaiv kab mob hauv lub qhov ncauj;
  • nrog kev kho ua ke (ib nrab tsis kam rau hypoglycemic qhov ncauj tshuaj);
  • nrog mono - lossis kev sib txuas ua ke txoj kev kho thaum phais mob;
  • nrog cov kab mob sib cuam tshuam;
  • nrog mob ntshav qab zib hauv cov poj niam cev xeeb tub, thaum kev noj zaub mov noj tsis tau ua rau cov nyhuv xav tau.

Tsuas tshuaj thiab tswj hwm

Raug tshem tawm rau kev txhaj tshuaj subcutaneous. Cov tshuaj tiv thaiv yog hypoglycemia, kev tiv thaiv tsis txaus.

Rosinsulin C yog muab tshuaj subcutaneously 1-2 zaug hauv ib hnub, txog ib nrab ib teev ua ntej noj mov. Txhua zaus, qhov chaw txhaj tshuaj yuav tsum tau hloov. Hauv qee kis, tus kws endocrinologist tuaj yeem sau ntawv rau tus neeg mob txhaj tshuaj ntawm cov tshuaj.

Ua tib zoo mloog! Kev tswjhwm ntawm insulin ntawm ib nrab sijhawm yog txwv tsis pub! Hauv txhua kis, tus kws kho mob ib leeg xaiv cov koob tshuaj, uas yuav yog nyob ntawm cov yam ntxwv ntawm chav kawm ntawm tus kab mob thiab cov ntsiab lus ntawm cov piam thaj hauv cov ntshav thiab zis.

Cov koob tshuaj li niaj zaus yog 8-24 IU, uas muab 1 zaug nyob rau ib hnub, rau qhov no koj tuaj yeem siv insulin koob txhaj nrog ib rab koob tshem tau.
Hauv cov menyuam yaus thiab cov neeg laus uas muaj qhov tsis txaus siab rau cov tshuaj hormones, qhov koob tshuaj yuav raug txo mus rau 8 IU toj ib hnub, thiab, hloov pauv, rau cov neeg mob uas tsis tshua muaj siab, nws tuaj yeem raug nce rau 24 IU ib hnub lossis ntau dua.

Yog tias qhov koob tshuaj txhua hnub ntau dua li 0.6 IU / kg, nws raug tswj hwm 2 zaug hauv ib hnub nyob rau ntau qhov chaw. Yog tias cov tshuaj tau muab tshuaj tso rau hauv ib qho ntawm 100 IU ib hnub lossis ntau dua, tus neeg mob yuav tsum tau pw hauv tsev kho mob. Qhov kev hloov ntawm ib qho tshuaj insulin mus rau lwm qhov yuav tsum tau ua nyob ntawm kev saib xyuas ntawm kws kho mob.

Cov Tshuaj Pharmacokinetics

Cov tshuaj yog belongs rau nruab nrab-sijhawm ntev insulins, uas yog qhia:

  1. kom txo cov ntshav piam thaj;
  2. txhawm rau txhim kho qhov nqus ntawm cov piam thaj los ntawm cov ntaub so ntswg;
  3. lug txhim khu glycogenogenesis thiab lipogenesis;
  4. kom txo qis tus nqi ntawm cov piam thaj tso tawm los ntawm daim siab;
  5. rau cov synthesis protein.

Sab sij huam

Kev tsis haum tshuaj:

  • mob hlwb;
  • txog siav
  • urticaria;
  • txo hauv cov ntshav siab;
  • npaws.

Cov tsos mob hypoglycemic:

  1. nce hws;
  2. pallor ntawm daim tawv nqaij;
  3. kev xav ntawm kev tshaib plab;
  4. palpitations
  5. Ntxhov siab vim
  6. tawm hws;
  7. arousal
  8. tshee hnyo
  9. paresthesia nyob rau hauv lub qhov ncauj;
  10. tsaug zog
  11. kev nyuaj siab kev ntxhov siab;
  12. tus cwj pwm txawv;
  13. kev chim siab;
  14. qhov kev xav tsis meej ntawm kev txav chaw;
  15. ntshai
  16. hnov lus tsis pom kev thiab tsis pom kev;
  17. insomnia
  18. mob taub hau.

Yog tias koj tsis tuaj yeem txhaj tshuaj, txhaj tshuaj qis, tawm tsam keeb kwm ntawm kev kis mob lossis kub taub hau, yog tias koj tsis ua raws li kev noj zaub mov noj, koj tuaj yeem tsim kab mob ntshav qab zib acidosis thiab hyperglycemia:

  • tsis qab los noj mov;
  • kev nqhis dej
  • tsaug zog
  • hyperemia ntawm lub ntsej muag;
  • hnov tsis nco qab txog li ib tug neeg tsis nco qab lawm;
  • transient tsis pom kev thaum pib ntawm txoj kev kho.

Cov lus pom zoo tshwj xeeb

Ua ntej koj sau cov tshuaj los ntawm cov vial, nco ntsoov tias txoj kev daws teeb meem kom pom tseeb. Yog tias muaj kev txo qis lossis cov hws khov pom ntawm qhov kev npaj, tom qab ntawd nws siv tsis tau.

Qhov kub ntawm cov tshuaj rau kev tswj hwm yuav tsum sib haum rau chav tsev kub.

Tseem ceeb! Yog tias tus neeg mob tau mob kis, mob qog, hypopituitarism, Addison tus kab mob, lub raum tsis ua haujlwm ntev, nrog rau cov neeg muaj hnub nyoog 65 xyoos, yuav tsum tau txhaj tshuaj kho cov tshuaj insulin.

Cov laj thawj ntawm kev ua ntshav siab tuaj yeem yog:

  1. Hloov chaw ntawm cov tshuaj.
  2. Noj ntau dhau.
  3. Tsis noj mov.
  4. Cov kab mob uas txo qis qhov xav tau ntawm cov tshuaj.
  5. Ntuav, raws plab.
  6. Kev ua haujlwm ntawm lub adrenal cortex.
  7. Kev ntxhov siab rau lub cev.
  8. Hloov chaw txhaj tshuaj.
  9. Kev cuam tshuam nrog lwm yam tshuaj.

Thaum pauv tus neeg mob los ntawm tsiaj cov tshuaj insulin rau tib neeg cov insulin, yuav txo tau cov ntshav qab zib kom tsawg.

Kev piav qhia ntawm kev nqis tes ntawm cov tshuaj Rosinsulin P

Rosinsulin P hais txog cov tshuaj uas muaj cov nyhuv luv luv hypoglycemic. Ua ke nrog cov receptor ntawm cov roj ntsha ntawm sab nraud, cov tshuaj ua rau cov insulin receptor complex. Qhov no ua:

  • tsub kom cov synthesis ntawm cyclic adenosine monophosphate nyob rau hauv daim siab thiab rog hlwb;
  • txhawb cov txheej txheem intracellular (pyruvate kinases, hexokinases, glycogen synthases thiab lwm tus).

Txo hauv cov ntshav qab zib cov ntsiab lus tshwm sim vim yog:

  1. nce kev thauj mus los intracellular;
  2. kev tsim kho ntawm glycogenogenesis, lipogenesis;
  3. protein synthesis;
  4. txhim kho kev nqus ntawm cov tshuaj los ntawm cov ntaub so ntswg;
  5. txo qis hauv kev puas tsuaj ntawm glycogen (vim txo qis ntawm cov piam thaj los ntawm nplooj siab).

Tom qab tswj hwm subcutaneous, cov nyhuv ntawm cov tshuaj tshwm sim hauv 20-30 feeb. Qhov siab tshaj plaws nyob rau hauv cov ntshav tau tiav tom qab 1-3 teev, thiab txuas ntxiv ntawm kev nqis tes ua yog nyob ntawm qhov chaw thiab txoj kev ntawm kev tswj hwm, koob tshuaj thiab tus yam ntxwv ntawm tus neeg mob.

Kev ntsuas rau siv

Rosinsulin P yog siv rau hauv cov xwm txheej hauv qab no:

  1. Ntshav qab zib mellitus yam 1 thiab 2.
  2. Ib nrab tawm tsam cov tshuaj hauv lub qhov ncauj hypoglycemic.
  3. Kev sib txuas ua ke
  4. Ketoacidotic thiab hyperosmolar coma.
  5. Ntshav qab zib ketoacidosis.
  6. Mob ntshav qab zib muaj tshwm sim thaum cev xeeb tub.

Rau kev siv sib quas ntus:

  • thaum yug menyuam, raug mob, kev phais mob tom ntej;
  • ua ntej yuav hloov mus rau kev txhaj tshuaj nrog kev siv tshuaj insulin kom ntev;
  • nrog cov teeb meem metabolic;
  • nrog mob sib kis nrog kub taub hau.

Cov Yuav Tsum Muaj thiab dpas dej

Cov tshuaj tiv thaiv yog hypoglycemia, kev tiv thaiv tsis txaus.

Cov kab ke ntawm kev coj ntawm cov tshuaj thiab cov koob tshuaj hauv txhua kis tau txiav txim ntawm tus kheej. Lub hauv paus rau kev txiav txim siab cov koob tshuaj yog cov piam thaj hauv cov ntshav ua ntej thiab tom qab noj mov, cov yam ntxwv ntawm chav kawm ntawm tus kab mob thiab cov ntshav qabzib.

Rosinsulin P yog npaj rau subcutaneous, pob leeg thiab intramuscular thawj coj. Kev txhaj tshuaj tas ua tiav 15-30 feeb ua ntej noj mov. Feem ntau cov feem ntau, qhov kev daws teeb meem yog tswj xyuas subcutaneously.

thaum lub sijhawm ua haujlwm phais, mob ntshav qab zib ketoacidosis thiab coma, rosinsulin P yog muab tshuaj rau txoj leeg thiab intramuscularly, rau qhov no nws yog qhov yuav tsum paub txog kev txhaj tshuaj insulin kom raug thiab raug.

Nrog kev kho mob monotherapy, cov naj npawb ntawm cov kev txhaj tshuaj ib hnub yog 3 zaug. Yog tias tsim nyog, tuaj yeem nce ntxiv txog 5-6 zaug. Txhawm rau kom tsis txhob txhim kho lipodystrophy, hypertrophy ntawm adipose ntaub so ntswg, mob atrophy, nws yog ib qho tsim nyog yuav tsum hloov chaw txhaj tshuaj txhua lub sijhawm.

Kev tsis haum tshuaj:

  • mob hlwb;
  • txog siav
  • txo hauv cov ntshav siab;
  • urticaria;
  • npaws.

Cov tsos mob ntawm tus mob hypoglycemia:

  1. nce hws;
  2. tachycardia;
  3. arousal
  4. tsaug zog
  5. pallor ntawm daim tawv nqaij;
  6. kev xav ntawm kev tshaib plab;
  7. kev xav ntawm kev ntxhov siab;
  8. tawm hws;
  9. tshee hnyo
  10. paresthesia nyob rau hauv lub qhov ncauj;
  11. hnov lus tsis pom kev thiab tsis pom kev;
  12. qhov kev xav tsis meej ntawm kev txav chaw;
  13. Kev Nyuaj Siab
  14. tus cwj pwm coj txawv txawv;
  15. kev chim siab;
  16. apathy
  17. insomnia
  18. mob taub hau.

Tawm tsam keeb kwm yav dhau los ntawm kev kis tus kab mob los yog kub taub hau, nrog rau kev txhaj tshuaj tsis nco qab, ib koob tshuaj qis, thiab yog tias kev noj zaub mov tsis ua raws, tus neeg mob tuaj yeem tsim muaj cov ntshav qab zib acidosis thiab hyperglycemia:

  • tsis qab los noj mov
  • kev nqhis dej
  • tsaug zog
  • o ntawm lub ntsej muag;
  • hnov tsis nco qab txog li ib tug neeg tsis nco qab lawm;
  • transient tsis pom kev thaum pib ntawm txoj kev kho.

Cov lus pom zoo tshwj xeeb

Ua ntej sau cov rosinsulin C los ntawm ib lub khob, nco ntsoov tias cov tshuaj yog qhov tseeb. Yog tias poob qis lossis ua kom muaj zog nyob hauv insulin, nws siv tsis tau. Qhov ntsuas kub ntawm kev txhaj tshuaj yuav tsum nyob ntawm chav sov.

Ua tib zoo mloog! Yog tias tus neeg mob tau kis mob, kev cuam tshuam ntawm cov thymus caj pas, hypopituitarism, Addison tus kab mob, mob raum tsis ua haujlwm, ntxiv rau cov neeg muaj hnub nyoog 65 xyoos, yuav tsum tau txhaj tshuaj insulin.

Qhov tshwm sim ntawm kev ua qog ntshav tuaj yeem yog:

  1. Hloov cov tshuaj.
  2. Kev noj tshuaj ntau dhau.
  3. Tsis noj mov.
  4. Cov kab mob uas txo qis qhov xav tau ntawm cov tshuaj.
  5. Xeev siab, raws plab.
  6. Ua tsis tau adrenal cortex muaj nuj nqi.
  7. Lub cev qoj ib ce.
  8. Hloov chaw txhaj tshuaj.
  9. Kev cuam tshuam nrog lwm yam tshuaj.

Thaum pauv hloov tus neeg mob los ntawm tsiaj cov tshuaj insulin rau tib neeg cov tshuaj insulin, kev txo qis hauv cov ntshav qab zib yog tau.

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