Glipizide yog ib yam khoom uas yog ib feem ntawm ntau cov tshuaj hypoglycemic los tswj cov piam thaj hauv ntshav qab zib hom 2.
Nws qhov kev siv tau ncaj ncees rau qee kis uas kev noj zaub mov ua si thiab kev ua kom lub cev tsis tuaj yeem ua rau txo qis qis cov ntshav qab zib, nrog rau cov teeb meem microangiopathy, uas yog, kev puas tsuaj rau cov ntshav me me.
Ua ntej yuav noj cov tshuaj, tus neeg mob yuav tsum paub zoo txog kev siv cov tshuaj thiab dab tsi yog nws contraindicated? Ntxiv rau, nws yuav tsum tau kawm txog kev tshuaj xyuas txog kev siv tshuaj ntawm cov neeg mob thiab cov kws kho mob, thiab yog tias tsim nyog, kuj yuav tsum kawm seb analogues ntawm Glipizide muaj nyob.
Cov ntaub ntawv dav dav txog kev quav yeeb tshuaj
Qhov kev tivthaiv no yog tus neeg sawv cev hluavtaws hypoglycemic.
Glipizide tsis tuaj yeem yaj nyob rau hauv dej los yog dej cawv, txawm li cas los xij, ib qho kev daws teeb meem NaOH (0.1 mol / L concentration) thiab dimethylformamide yaj ua qhov feem no zoo. Qhov tshuaj yeeb tshuaj no yog tsim tawm hauv cov ntsiav tshuaj uas zoo sib xws thiab txhawb nqa cov ntsiav tshuaj tso tawm.
Thaum ib yam tshuaj nkag mus rau hauv lub cev mob ntshav qab zib, nws txhawb txoj kev tawm ntawm cov kua dej los ntawm kev ua haujlwm beta hlwb ntawm cov islet apparatus.
Glipizide ua raws li hauv qab no:
- Txo cov piam thaj thiab glycosylated hemoglobin ntawm lub plab khoob.
- Muaj qabzib ntxiv ua kom lub siab ntev, nrog rau qee qhov tsawg - tshem ntawm cov kua dawb.
- Txo cov ntxim nyiam ntawm hyperglycemia tom qab noj mov.
Cov tshuaj tiv thaiv tsis cuam tshuam rau cov lipid metabolism. Nws ua kom nws pib tom qab 30 feeb ntawm kev pub nkag thiab txuas ntxiv txhua hnub. Qhov siab tshaj plaws ntawm cov tshuaj pom tau yog tom qab 1-3 teev ntawm kev siv lub qhov ncauj.
Nws yuav tsum raug sau tseg tias Glipizide yog qhov zoo dua tsis siv thaum noj mov, vim tias nws qhov kev nqus tag nrho poob qis. Biotransformation ntawm cov tshuaj tshwm sim hauv lub siab.
Qhov feem cuam yog tawm ua cov metabolite nrog rau quav thiab tso zis, suav nrog tsis hloov pauv - kwv yees li 10%.
Cov lus qhia rau kev siv
Ua ntej siv cov kev npaj ua muaj glipizide, koj yuav tsum sab laj tus kws kho mob lossis tus kws kho mob endocrinologist. Tsuas yog tus kws kho mob tuaj yeem kwv yees qhov tsim nyog ntawm kev siv ib lossis lwm qhov kev daws teeb meem.
Tom qab yuav cov tshuaj, koj yuav tsum ua tib zoo nyeem phau ntawv qhia. Qhov tshuaj thawj zaug yog 5 mg, uas tau muab tshuaj ib hnub ua ntej lossis tom qab noj mov. Sij hawm dhau mus, nrog rau tus mob ntshav qab zib ib txwm muaj kev noj qab haus huv, kev noj tshuaj tuaj yeem maj mam nce mus rau 15 mg, faib cov thawj coj ntawm cov tshuaj ntau zaus.
Cov lus qhia tau hais tias yog tias cov koob tshuaj tau ploj lawm, tab sis ob peb teev dhau los txij li cov koob tshuaj tsim nyog, cov tshuaj yuav tsum tau muab tshuaj sai sai. Tab sis yog tias yuav luag ib hnub tau dhau los, koj yuav tsum ua raws li kev coj noj coj ua.
Cov neeg mob ntawm lub hnub nyoog qib siab thiab kev txom nyem los ntawm daim siab pathology yuav tsum siv cov tshuaj hauv qhov tsawg kawg nkaus - 2.5 mg ib hnub twg, thiab lub caij nyoog ntev-tso cov ntsiav tshuaj - los ntawm 5 mus rau 10 mg ib zaug, nyiam dua thaum sawv ntxov.
Zoo li txhua lwm yam tshuaj, Glipizide xav tau cia kom deb ntawm cov menyuam yaus hauv qhov chaw tiv thaiv los ntawm cov av noo ntawm chav tsev kub.
Cov txheej txheem sib tsoo thiab cov phom sij uas yuav muaj
Qee yam mob ntshav qab zib siv tsis tau cov tshuaj no.
Cov lus qhia muaj contraindications ntsig txog tus neeg mob rhiab rau cov khoom ntawd, mob ntshav qab zib tsis nco qab, insulin-hom mob ntshav qab zib, ketoacidosis, kub taub hau, kev phais tsis ntev los no, cev xeeb tub thiab lub sijhawm pub mis niam.
Hauv cov xwm txheej hnyav tshwj xeeb, kev siv Glipizide tuaj yeem siv tau thaum lub sijhawm menyuam yaus. Tab sis nws siv yuav tsum tau tso tseg 1 lub hlis ua ntej hnub yug.
Thaum lub sij hawm pub mis niam, noj cov tshuaj yog nruj me ntsis txwv tsis pub.
Tus kws kho mob qhov kev sab laj ua ntej siv Glipizide yuav tsum, vim kev tswj hwm tsis raug cai ntawm cov tshuaj tuaj yeem ua rau ntau qhov kev tsis txaus siab:
- mob taub hau, tsis meej pem meej pem, nkees, mob tawm tsam, leeg ntshav ntswg, dias taub hau, kev nyuaj siab, mob taub hau, ntxhov siab, qhov muag thiab pom pob txha;
- flatulence, xeev siab, ntuav, impurities ntawm cov ntshav nyob rau hauv cov quav, cem quav, dyspepsia thiab anorexia;
- khaus, tawm pob, thiab ua xua;
- pharyngitis, rhinitis thiab dyspnea;
- txuam nrog cov hlab plawv thiab cov ntshav tsim: arrhythmia, syncope, cia ntawm kub flashes thiab kub siab;
- kuj yog glycemia hauv hom 2 mob ntshav qab zib mellitus mus txog glycemic coma.
- ntsig txog kab mob genitourinary system: txo qis kev sib deev muaj siab thiab dysuria.
Ntxiv rau, ob peb lwm cov kev phiv tuaj yeem tshwm sim - ua ke, tsis nqhis dej tsis txaus, myalgia, mob caj pas, tawm hws, mob ib ce.
Nqi, tshuaj xyuas thiab analogues
Txij li thaum glipizide yog ib qho kev ua haujlwm, ntau yam tshuaj muaj cov tshuaj muaj peev xwm nrhiav tau ntawm cov khw muag tshuaj ntawm Lavxias. Piv txwv, Glucotrol CL thiab Glibenez Retard. Nyob ntawm daim ntawv tso tawm, tus nqi ntawm cov tshuaj Glucotrol HL thaj tsam ntawm 280 txog 360 rubles, thiab Glibenez Retard - los ntawm 80 txog 300 rubles.
Kev txheeb xyuas ntawm cov neeg mob ntshav qab zib feem ntau uas tau noj cov tshuaj no yog qhov txaus siab. Txawm li cas los xij, ntau yam tau sau tseg tias qhov kev kho mob ntawm glipizide poob qis dua lub sijhawm, yog li nws feem ntau siv nrog lwm cov tshuaj mob ntshav qab zib. Ntawm qhov zoo ntawm cov tshuaj tuaj yeem paub qhov txawv yooj yim ntawm kev siv thiab tus nqi siab ntawm cov tshuaj muaj glipizide.
Nyob rau hauv rooj plaub thaum thaum ib cov tshuaj tsis haum vim yog contraindications los yog tsis zoo, tus kws kho mob sau ib qho tshuaj analogue. Cov tshuaj no suav nrog:
- Movoglek.
- Antidiab.
- Glibenesis.
- Minidiab.
Yog tias tsis pom zoo los ntawm tus kws kho mob, kev noj tshuaj rau tus kheej tsis tsim nyog. Kev npaj muaj glipizide tuaj yeem muaj kev cuam tshuam tsis zoo rau tib neeg lub cev. Nrog rau kev siv cov tshuaj kom zoo, koj tuaj yeem ua kom cov piam thaj kom zoo li qub thiab tshem tawm cov tsos mob ntshav qab zib. Tab sis kuj peb yuav tsum tsis txhob hnov qab txog kev kho kev qoj ib ce rau ntshav qab zib thiab kev noj zaub mov kom zoo.
Hauv cov yeeb yaj kiab hauv tsab xov xwm no, kws kho mob yuav tham txog tshuaj kho ntshav qab zib.
