Cov roj (cholesterol) hauv ntshav qab zib yog ib qho kev ua kom zoo rau tus neeg mob.
Qhov no yog vim qhov tseeb tias nrog kev nce hauv qib roj (hauv Asmeskas cov ntawv nyeem "cov roj (cholesterol)", lub voj voos ntawm cov kab mob ntawm cov kab mob ntawm cov hlab plawv tau kaw.
Qhov ntau dua ntawm cov lipids nyob rau hauv cov ntshav, ntau dua qhov kev pheej hmoo ntawm tus mob chua leeg, uas, nyeg, muaj kev pheej hmoo ntawm ntshav qab zib mellitus mob.
Hauv qhov no, nws yog qhov tseem ceeb heev uas yuav tsum tau ntsuas ntsuas qhov tsis haum cov roj (cholesterol) hauv ntshav qab zib.
Muaj ob hom roj endogenous, nyob rau hauv raws li nws qhov ntom, hauv kev sib xyaw nrog cov thauj cov protein:
- lipoproteins tsawg thiab qis heev (LDL, VLDL) yog "tsim kev puas tsuaj" atherogenic lipids thiab muaj teeb meem rau lub cev;
- qhov siab thiab qhov feem ntau lipoproteins (HDL, HDL), ntawm qhov tsis sib xws, muaj cov tshuaj tiv thaiv antiatherogenic thiab tiv thaiv kev pheej hmoo ntawm kev tsim cov atherosclerosis ntawm cov hlab ntshav.
Cov neeg mob ntshav qab zib yog yam ntxwv tau nce ntxiv ntawm LDL thiab cov theem HDL tsawg dua piv rau cov tib neeg uas muaj kev noj qab haus huv feem ntau. Kev nce qib hauv LDL thiab TAG cov cim taw qhia muaj kev pheej hmoo ntawm kev tsim mob vascular kev puas tsuaj sai. Cov piam thaj hauv cov ntshav ua rau lub cev tsis txaus ntawm ob feem ntawm lipoproteins. Kev nce ntshav lipids hauv ntshav qab zib yog txuam nrog cov hauv qab no pathological:
- Cov ntshav ntawm tus neeg mob ntshav qab zib mellitus tau tshaj tawm kev yoog thiab tau tso ntshav dawb.
- Vim tias mob ntev ntev, viav endothelium ntau puas yooj yim thiab nquag muaj qhov tsis zoo tshwm sim.
- Kev nce ntxiv ntawm cov piam thaj ua rau kev nce hauv lub sijhawm ntawm atherogenic lipoproteins hauv ntshav dej.
- Qib qis ntawm cov los tiv thaiv atherogenic lipids ua rau muaj kev pheej hmoo ntawm cov hlab plawv kev puas tsuaj loj.
- Cov deposition ntawm lipid plaques rau ntawm cov hlab ntsha ua rau lub hauv paus ua kom muaj ntshav qab zib.
- Kev sib xyaw ntawm ob qho pathologies txhim kho cov nyhuv ntawm txhua.
Hauv kev sib txuas nrog cov qauv hais los saum no ntawm lub hwj chim, tag nrho cov roj (cholesterol) hauv ntshav qab zib mellitus yuav tsum tau soj ntsuam tas li. Xws li tus neeg mob yuav tsum tau rau npe nrog tus kws kho qhov muag endocrinologist thiab kws kho mob.
Tus nqi ntawm cov cholesterol hauv ntshav qab zib
Raws li cov kev tshawb fawb soj ntsuam tsis ntev los no, kev nce cov roj cholesterol hauv cov ntshav qab zib mellitus ua rau muaj kev nce nrawm ntawm angiopathy thiab ua rau muaj kev pheej hmoo ntawm cov kab mob plawv.
Txawm hais tias muaj mob hnyav ntawm cov kab ke sib xyaw ua ke no, nws teb tau zoo heev rau kev kho.
Kev tshuaj xyuas tas li ntawm kev yoo mov glycemia, ntshav siab thiab lipoprotein concentration pab ua kom tus neeg mob tus mob tsis zoo.
Ntawm cov ntshav qab zib ntawm thawj hom (tus hluas) nrog kev soj ntsuam tas li ntawm qib glycemia, qhov tsis zoo ntawm lipid profile tsis pom. Tab sis rau cov neeg mob uas mob ntshav qab zib thiab mob ntshav qab zib hom 2, qhov xwm txheej no yuav txawv.
Kev kuaj ntshav txuas ntxiv rau cov lipids hauv ntshav qab zib hom 2 yog tus cwj pwm los ntawm:
- txo cov roj HDL;
- cov theem qis ntawm HDL;
- nce LDL ntau ntau;
- nce qib ntawm VLDL;
- nce rau hauv tag nrho cov cholesterol;
- nce qib ntawm TAG.
Cov kev hloov pauv ntawm cov lipid profile ua rau qhov txo ntawm atherogenic lipoproteins ntawm phab ntsa ntawm endothelium thiab ua rau muaj kev cuam tshuam ntawm lumen ntawm cov hlab ntsha. Cov me me ntawm cov kab mob antiatherogenic lipids tsis muaj peev xwm tiv thaiv kev loj hlob ntawm atherosclerotic lesions ntawm cov hlab ntsha. Cov txiaj ntsig Triglycerides kuj tseem cuam tshuam rau cov txheej txheem ntawm kev hloov pauv ntawm cov lipids. Vim tias lub sij hawm obliteration ntawm lub nkoj, hypoxia ntawm cov ntshav muab cov ntaub so ntswg tsim.
Hauv kev mob tsis haum lub cev thiab cov pa oxygen tsis txaus, kabmob qog ib ce hloov zuj zus, hauv mob hnyav - necrosis. Tus mob ntshav qab zib siab uas muaj cov roj (cholesterol) muaj feem ntau yuav tau txais ib qho mob myocardial infarction lossis mob hlwb sai sai rau yav pem suab.
Tsis tas li, ntshav qab zib micro- thiab macroangiopathy hloov zuj zus nrog kev txuas ntawm cov txheej txheem atherosclerotic.
Kev cuam tshuam ntawm cov kua dej thiab cov roj (cholesterol) hauv cov ntshav
Txog rau hnub tim, cov kev tshawb fawb tau ua nyob ntawm cov nyhuv ntawm insulin exogenous ntawm cov ntshav biochemistry, suav nrog rau qib lipid. Kev nce zuj zus ntawm cov tshuaj hormone insulin hauv cov ntshav ua rau kev nce me me ntawm cov feem atherogenic lipids thiab ib qho kev poob qis hauv cov concentration ntawm antiatherogenic lipids. Ntxiv rau, cov roj (cholesterol) qhov tseem ceeb yog cov yam ntxwv ntawm cov neeg mob uas muaj peev xwm tiv thaiv cov tshuaj insulin hnyav.
Cov haujlwm qoj ib ce ua rau txo qis cov roj (cholesterol). Cov ntsiab lus no tseem ceeb rau kev rog lossis alimentary rog. Rau cov neeg mob uas muaj thawj hom ntshav qab zib, soj ntsuam glycemia tuaj yeem txo cov roj (cholesterol) ib zaug.
Nrog kev soj ntsuam kom zoo ntawm cov piam thaj nyeem, kev ntsuas kev txheeb ze ntawm cov ntshav cov ntshav hauv cov qib raug sau tseg. Hmoov tsis zoo, nrog kev kho ntshav qab zib kom tsis raug nyob hauv thawj hom mob ntshav qab zib, mob ntshav qab zib ntau heev kuj tseem ua rau mob.
Qhov no ua rau muaj kev pheej hmoo loj ntawm atherosclerosis hauv pawg neeg mob no. Yuav luag txhua tus neeg mob ntshav qab zib mellitus, kev puas siab puas ntsws vascular yog sau tseg. Kev puas tsuaj tshwm sim ntawm endothelium ntxiv cov roj (molecules) roj.
Qhov no ua rau muaj kev loj hlob sai ntawm atherogenic tshuaj thiab muaj kev pheej hmoo ntawm thrombosis, tav kev ntawm lumen ntawm cov hlab ntsha thiab kev txhim kho ntawm cov mob caj dab coronary pathologies.
Cov hau kev tseem ceeb ntawm kev kho
Qhov uas paub tseeb tias yuav txo cov roj hauv cov ntshav yog los ntawm kev hloov kho ntawm kev ua neej.
Tus neeg mob yuav tsum xub sab laj nrog tus kws kho mob tshwj xeeb rau tswv yim.
Nws kuj yog ib qho tseem ceeb kom nruj rau cov tshuaj noj, coj lawv nruj me ntsis raws li kws kho mob sau tseg.
Cov lus qhia hauv qab no rau kev noj cov rog yuav pab txhim kho kev ua kom tus kabmob thiab lub neej zoo rau tus neeg mob:
- Ntau dhau los ntawm kev noj cov nqaij rog monounsaturated thiab cov carbohydrates sai tuaj yeem nce qhov siab ntxiv ntawm cov roj cholesterol hauv cov ntshav. Lawv siv yuav tsum tau txwv.
- Tsis tas yuav tshem tawm cov rog kom rog los ntawm kev noj haus.
- Qhov muaj txiaj ntsig zoo tshaj plaws hauv cov zaub mov yog cov rog polyunsaturated. Cov neeg sawv cev ci ntsa iab ntawm cov uas yog Omega-3 thiab Omega-6 fatty acids. Feem ntau cov omega acids muaj nyob hauv roj zaub thiab roj ntses.
Ib txoj kev ua pov thawj ntawm pej xeem kom tshem tawm surges nyob rau hauv cov ntshav qab zib thiab normalize cov roj cholesterol - txoj kev noj qab nyob zoo, hom thiab kev noj zaub mov zoo.
Kev kho mob tseem ceeb tshaj plaws rau hypercholesterolemia yog kev siv statins. Pab pawg no cov tshuaj muaj cov cim antiatherogenic ua haujlwm. Ntshav Qab Zib Hom 2 thiab ntshav siab yog cov kab mob, feem ntau pom zoo.
Cov pab pawg npaj tshuaj no yuav tsum tau ua ke nrog kev hloov kho hauv kev ua neej, kev hloov pauv ntawm kev noj zaub mov kom zoo ntxiv nrog cov nroj tsuag thiab cov rog zoo, nrog rau kev ua si lub cev tsis tu ncua. Xws li txoj hauv kev rau txoj kev kho yuav txo qis kev pheej hmoo mob plawv tsis txaus. Cov kev kho mob kuj yog nyob ntawm lipid profile, tus neeg mob noj qab haus huv, tus yam ntxwv hnub nyoog thiab muaj qhov txaus ntshai.
Cov kev sib raug zoo ntawm cov ntshav qab zib thiab atherosclerosis tau piav qhia hauv video hauv kab lus no.
