Chlorhexidine yog ib tus neeg sawv cev los ntawm pawg ntawm antiseptics rau kev siv sab nraud hauv ntau thaj chaw ntawm tshuaj, cosmetology, rau kev ntxuav ntawm cov cuab yeej, ntxuav vaj tse thaj chaw.
ATX
D08AC02 - cov tshuaj tiv thaiv kabmob thiab tshuaj tua kabmob uas tsis yog los ntawm chav kawm ntawm biguanides thiab amines - Chlorhexidinum. INN - Chlorhexidine.
Chlorhexidine yog ib tus neeg sawv cev los ntawm pawg ntawm antiseptics rau kev siv sab nraud hauv ntau thaj chaw ntawm tshuaj, cosmetology, rau kev ntxuav ntawm cov cuab yeej, ntxuav vaj tse thaj chaw.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv ntau daim ntawv qhia, uas sib txawv hauv cov muaj pes tsawg leeg ntawm kev zam thiab qhov sib npaug ntawm cov tshuaj nquag.
Tshuaj
Cov tshuaj yeeb tshuaj yog chlorhexidine bigluconate. Cov khoom ntim hauv lub hwj yas nrog lub ntim tsis muaj khob lossis khob ntim. 100 ml ntawm cov khoom muaj 0.05% (0.25 ml) ntawm kev daws ntawm qhov nquag. Txhua lub thawv tau muab tso rau hauv lub thawv laminated.
Hauv lub hwj loj loj ntawm 100 ml thiab 0.5 l, ib qho kev daws teeb meem 20% yog tsim.
Txau
Tshuaj tsuag yog muaj nyob rau hauv 45 ml yas hwj. Hauv kev sib xyaw thiab kev tsom ntawm cov tshuaj nquag, nws tsis txawv ntawm 0.05% kev daws. Lub tank muaj nruab nrog lub tshuab twj tso kua mis txhawm rau txhawm rau ua kua.
Cov tswm ciab tso 5 pcs. hauv hlwv. Cov thawv ntawv ntim muaj 2 lub hlwv (No. 10).
Cov tswm ciab
Hais ntawm lub paum suppositories muaj:
- 20% (16 mg) chlorhexidine bigluconate daws;
- macrogol (polyethylene glycol) 1500 thiab 400 ua cov muab tub lim.
Cov tswm ciab muaj lub khauj khaum ntsej muag, xim ntawm daim tawv dawb txog daj dawb. Marbling ntawm qhov saum npoo yog tso cai. Cov tswm ciab tso 5 pcs. hauv hlwv. Cov thawv ntawv ntim muaj 2 lub hlwv (No. 10). Cov pub ntxiv yog tseem muaj nrog cov khoom qis dua - 8 g. Lawv yog cov menyuam yaus qhov kev pab cuam ntawm lub chaw mos.
Cawv
Chlorhexidine gel suav nrog:
- 20% daws (5.0 mg) ntawm cov tshuaj nquag;
- glycerin;
- natrozole stabilizer;
- raws lactone;
- preservative E218;
- distilled dej.
Cov khoom lag luam yog pob tshab gel tsis muaj xim, viscous sib xws, homogeneous, ntxhiab tsw. Cov kua nplaum tau muab tso rau hauv 50 g laminated raj
Tshuaj pleev, ntxiv rau qhov muaj feem tseem ceeb ntawm 0.05% chlorhexidine bicarbonate daws, muaj ntau yam kev pabcuam thiab tshuaj muaj txiaj ntsig - zinc, hydrocortisone, lidocaine.
Tshuaj pleev
Tshuaj pleev, ntxiv rau qhov muaj feem tseem ceeb ntawm 0.05% chlorhexidine bicarbonate daws, muaj ntau yam kev pabcuam thiab tshuaj muaj txiaj ntsig - zinc, hydrocortisone, lidocaine.
Mechanism ntawm kev ua
Nws cuam tshuam nrog phosphorus pawg ntawm lipids nyob rau hauv lub cell membrane: nws txoj kev ncaj ncees tau ua txhaum, cov ntsiab lus sab hauv ntawm lub xov tooj ntawm tes ua rau nplua nplua nplua (nag lossis daus tiv thaiv), potassium thiab phosphorus ploj. Ib tus kab mob cell tuag.
Raws li qhov txiaj ntsig ntawm kev kho mob ntawm chlorhexidine nrog cov kab mob fungal, kev sib kis ntawm cov kab mob fungal txo.
Nyob ntawm cov siab, cov tshuaj muaj cov yam ntxwv txawv ntawm cov kab mob hauv lub cev:
- tua -> 0.01% - cov "molecules" ntawm cov khoom "ua rau" nyob rau hauv lipid txheej ntawm daim nyias nyias thiab kev tsim kho nws tus qauv, zoo li lub denser packing, uas ua txhaum lub permeability ntawm membrane;
- Ua rau qis kev loj hlob thiab rov ua dua tshiab - <0.01% - ua rau cov neeg kho tshuab "kev zom" ntawm cov roj molecules los ntawm chlorhexidine lwg me me, permeability nce thiab cell co nce.
Cov tshuaj tua kab mob ua hauj lwm zoo tiv thaiv cov kab mob gram-positive thiab gram-tsis zoo (tshwj tsis yog Koch's bacillus), protozoa (Trichomonas), HSV. Nrog kev tawm tsam ntawm cov tshuaj tua kab mob-cov kab mob, qhov tseem ceeb ntawm kev kho mob hauv zos nce. Kev siv cov tshuaj muaj zog cov tshuaj tua kab mob ua rau kom txo qis cov tshuaj tiv thaiv cov kab mob tsawg.
Raws li kev kho mob los ntawm kev kho tus kab mob fungal nrog Chlorhexidine, thaj chaw ntawm fungal spore faib tsawg zuj zus, uas txiav txim qhov kev ua haujlwm ntawm cov tshuaj muaj feem cuam tshuam nrog ib qho pwm ntawm cov genus Candida thiab lwm yam kab mob sib kis uas ua rau fungal kis ntawm daim tawv nqaij, rau tes, tawv taub hau. Fungicidal cov yam ntxwv raug txawm tias nyob hauv kev daws 0.05%.
Cov tshuaj ua txhaum lub peev xwm ntawm microorganisms kom ua raws.
Chlorhexidine tau pom tias muaj kev tiv thaiv zoo rau kev tiv thaiv methicillin-resistant staphylococci uas ua rau mob dermatological.
Kuj tau txais cov ntaub ntawv lub hom phiaj ntawm cov kev ua tsis zoo ntawm cov microflora uas muaj ntau cov nplej:
- Cov poov xab-zoo li fungus Malassezia spp., Uas ua rau cov kab mob ntawm daim tawv nqaij - seborrhea, lichen, dermatitis, hyperkeratosis, psoriasis, thiab nrog rau kev txo qis hauv kev tiv thaiv - cov kab mob hauv lub cev.
- Pseudomonas aeruginosa Pseudomonas aeruginosa, pom muaj hauv kev qog, mob ua paug, cystitis, enteritis. Qhov nyuaj ntawm kev siv tshuaj tua kab mob yog vim muaj qhov tsim los ntawm kev ua kom tsis haum tus kab mob.
Thaum kawm txog cov txiaj ntsig ntawm Chlorhexidine ntawm pathogenic microorganisms ntawm lub qhov ncauj ntawm qhov ncauj, tau pom tias nws ua haujlwm tau zoo txawm tias muaj kev tiv thaiv qhov siab (0.05%), tab sis nws qhia qhov tshwm sim zoo tshaj plaws ntawm cov gel, vim tias, tsis zoo li cov tshuaj, nws tsis txo qhov nrawm nrawm ntawm kev kho. (rov qab los).
Cov tshuaj tsis yog tsuas yog ntxuav tawm, nws cuam tshuam cov txheej txheem ntawm kev tsim biofilm - lub zej zog kev tsim qauv ntawm cov kab mob me me uas txuas rau saum npoo ntawm cov hlwb, cov khoom organic thiab thaj chaw. Cov tshuaj ua txhaum lub peev xwm ntawm microorganisms kom ua raws.
Chlorhexidine ua rau cov poov xab zoo li pwm Malassezia spp., Ua rau muaj kev tiv thaiv qis hauv lub cev.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog npaj rau kev kho hauv zos. Thaum ua ntawv thov rau saum npoo ntawm epidermis, nws tsis nkag mus rau hauv cov kab ke hauv lub cev, muab pom tias cov nqaij mos tsis muaj qhov tsis zoo. Txoj kev daws teeb meem muaj qhov siab ntawm qhov kev ruaj khov thiab tom qab thov ntev mus txuas ntxiv ua. Nws tseem ua hauj lwm zoo, txawm hais tias me ntsis qis dua, nyob rau ntawm muaj cov kua nruab nrog cev.
Thaum noj, nws tsis yog nqus hauv plab hnyuv lumen. Lub ntsiab yog excreted thiab tsuas yog 1% - nrog zis.
Kev ntsuas rau siv
Hauv kev siv tshuaj, cov tshuaj yog siv rau kev kho mob thiab kho kom zoo rau hauv kev sib txuas nrog cov kab mob ua rau muaj kev cuam tshuam ntawm chlorhexidine bicarbonate:
- Hauv kev kho hniav rau caries, gingivitis, periodontitis, stomatitis, aphthae, rau kev huv thiab tswj qhov ncauj huv. Tshem tawm cov ntxhiab tsw, ua rau ntshav thiab o ntawm cov pos hniav, ntxiv dag zog rau cov hniav, pab txo cov caries, tom qab cov txheej txheem sib kis, rau kev ua kom tsis huv ntawm cov hniav.
- Hauv otolaryngology - rau cov kab mob ntawm oropharynx (tonsillitis, tonsillitis, pharyngitis), rau kev nqus tau pa tshuaj kho mob ntsws, mob ntsws, mob ntsws, mob ntsws. Rau instillation rau hauv lub qhov ntswg thiab pob ntseg, cov tshuaj tsis siv.
- Hauv kev kho mob rau poj niam thiab kev mob plab - nrog vulvitis, colpitis, vaginosis, candidiasis (thrush), STDs. Raws li kev tiv thaiv kev kis kab mob hauv lub sijhawm postoperative, thaum lub sijhawm kuaj mob, tom qab sib deev tsis tau siv hnab looj.
- Hauv txoj hlab zis - nrog rau qhov mob tso zis, txoj hlab zis, txoj kev npaj rau kev soj ntsuam cov zais zis - cystoscopy. Cov tshuaj yeeb tshuaj yog siv hauv kev tsim cov yeeb yaj kiab pleev xim nrog chlorhexidine rau sab nraud thiab sab hauv.
- Hauv cov tawv nqaij thiab tshuaj pleev ib ce - nrog furunculosis, pob txuv, dermatosis, lichen, psoriasis, seborrhea.
- Hauv kev phais mob - rau kev kho qhov mob purulent, trophic mob rau sab hauv tsev, phais mob sutures, rau kev kho mob ntawm kub hnyiab, tiv thaiv kev ua laib thiab sepsis, hauv kev kho mob ntawm ko taw mob ntshav qab zib.
Cov Yuav Tsum Muaj
Tsis txhob siv nrog:
- predisposition rau kev tsis haum;
- viav vias mob ntawm qhov mob epidermis.
Ceev faj yog qhia kom siv cov tshuaj thaum qhia rau hauv cov kab noj hniav ntawm lub cev urogenital.
Yuav siv cov tshuaj chlorhexidine li cas?
Cov txheej txheem ntawm kev siv tshuaj yog nyob ntawm lub hom phiaj, daim ntawv, hnub nyoog ntawm tus neeg mob, kev kub cev:
| Concentration (%) | Teem Caij Nyoog |
| 0,05 | Thaum muaj kev ua txhaum ntawm kev ncaj ncees ntawm daim tawv nqaij sib kis, hauv kev kho hniav, nrog ENT cov kab mob, kev tiv thaiv ntawm STD, rau kev douching, thaum yaug cov cutlery thiab tais diav. |
| 0,1 | Kev txiav txim siab ntawm sutures, hauv kev kho hniav, kho ntawm ENT pathologies, tawg, scuffs, hlwv ntawm daim tawv nqaij. |
| 0,2 | Thaum ua cov hniav cuav, hauv cov kws kho mob poj niam thiab urology, nyob rau hauv kev npaj rau cov txheej txheem kuaj mob hauv thaj chaw urogenital. |
| 0,5 | Hauv kev kho hniav, nrog rau cov kabmob ENT, kev saib xyuas tom qab cov txheej txheem pleev ib ce - kev pleev xim, tho; kho pob txuv, pob ntxau. |
| 1,0 | Kom tsis muaj menyuam cov cuab yeej, ntxuav tu thaj chaw, rooj tog zaum, khoom siv, khoom cua txias. |
Cov dej cawv ua rau siv cov tshuaj tua kab mob kom tsis haum, tshuaj tua kab mob rau thaj chaw phais. Cov dej cawv hauv cawv tau npaj los ntawm 1 feem ntawm 20% mloog zoo thiab 40 feem ntawm 70% cawv.
Txhawm rau txhawm rau, kho qhov mob thiab kub hnyiab, douching thiab nruab rau hauv qhov zis thiab tso zis, tso kua tshuaj aqueous ntawm qhov tsis muaj zog concentration siv.
Lub paum ntawm qhov chaw mos yog siv rau cov kab mob kas cees thiab rau kev rho tawm ntawm tus neeg yug tus kwj dej. Koj tuaj yeem siv lawv thoob plaws tag nrho lub sijhawm ua tiav thiab sib deev. Cov menyuam yaus daim ntawv yog tshuaj rau cov menyuam ntxhais kom txog rau thawj lub hli ua ntej kev phais mob gynecological pathologies, vulvovaginitis.
Nkag (0.5%) siv rau kev kho mob tawv nqaij, hauv tshuaj pleev ib ce (pob txuv, ntxau, tom qab cov txheej txheem zoo nkauj). Hauv kev kho hniav, cov gel tau siv rau qhov ncauj tshwj xeeb - cov pos hniav raug rau nws txoj kev ua ntev. Cov kua nplaum siv los pleev cov nplai, cov hnab yas looj, tsim cov zaj duab xis tiv thaiv ntawm txhais tes.
Nkag (0.5%) siv rau kev kho mob tawv nqaij, hauv tshuaj pleev ib ce (pob txuv, ntxau, tom qab cov txheej txheem zoo nkauj).
Cov tshuaj ua haujlwm nquag ntawm cov tshuaj yog ib feem ntawm kev ua qab zib, pleev tshuaj, txhuam hniav, plasters, roj pleev, tshuaj pleev.
Yuav ua li cas yug me nyuam rau yaug?
Txhawm rau yaug, siv 0.05 thiab 0.1% aqueous tov ntawm chlorhexidine. Txhawm rau npaj cov khoom lag luam ntawm qhov xav tau xav tau, 200 ml dej tau los ntawm 20% kev mloog zoo thiab:
- 0.5 ml ntawm mloog zoo;
- 1.0 ml ntawm mloog zoo.
Sab sij huam
Nrog intolerance rau yeeb tshuaj, ua txhaum ntawm lub sijhawm ntawm kev tswj hwm, noj ntau npaum li cas, cov tawv nqaij ua xua hauv daim ntawv ntawm khaus, dryness, liab tuaj yeem pom. Thaum siv rau hauv kev kho hniav - ua kom tsaus nti ntawm txha hniav laus, ua txhaum ntawm saj, tsim ntawm tartar.
Nrog intolerance rau yeeb tshuaj, ua txhaum ntawm lub sijhawm ntawm kev tswj hwm, noj ntau npaum li cas, cov tawv nqaij ua xua hauv daim ntawv ntawm khaus, dryness, liab tuaj yeem pom.
Cov lus qhia tshwj xeeb
Kev daws ntawm Chlorhexidine ua ntau dua thaum kub kub, tab sis decomposes ntawm + 100 ° C. Zam kev kho mob nrog kev puas tsuaj rau tus txha nqaj qaum, pob txha taub hau, pob ntseg sab hauv. Lub qhov txhab nyob ze rau cov hlab ntsha ganglia tsis kho nrog chlorhexidine.
Kuv puas tuaj yeem ntxuav kuv ob lub qhov muag?
Kev siv tshuaj chlorhexidine rau kev ntxuav lub qhov muag tsis pom zoo, tsuas yog tshwj xeeb cov tshuaj pleev qhov muag uas muaj nws. Hauv kev xyaum, ib txoj kev daws teeb meem 0.05% yog siv los tshem cov kua paug ntawm lub tawv muag tawm ntawm qhov muag. Txawm li cas los xij, koj yuav tsum xyuas kom meej tias cov khoom tsis kis tau ntawm cov qog ua kua.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj tsis muaj qhov ua haujlwm zoo rau lub cev, yog li tsis muaj kev txwv rau nws txoj kev siv thaum cev xeeb tub. Nws tsis pom zoo kom kho cov kab nrib pleb hauv lub txiv mis ntawm lub mis thaum lub sijhawm pub mis, yog li kom tsis txhob ua rau qhov kub hnyiab ntawm lub caj pas ntawm qhov ncauj ntawm cov menyuam thiab cov tshuaj hauv lub plab zom mov.
Cov tshuaj tsis muaj qhov ua haujlwm zoo rau lub cev, yog li tsis muaj kev txwv rau nws txoj kev siv thaum cev xeeb tub.
Cov tshuaj chlorhexidine tuaj yeem muab rau me nyuam yaus?
Hauv cov lus qhia, cov tshuaj tsis pom zoo rau cov menyuam yaus hnub nyoog qis dua 12 xyoos.
Noj ntau dhau
Nrog rau kev siv sab nraud, kev kis ntau dhau tsis tau sau tseg. Yog tias cov tshuaj loj rau hauv cov hnyuv, cov qaug cawv heev tshwm sim, nrog cov tsos mob ntawm lub raum thiab daim siab ua haujlwm. Thaum raug lom, nws yog ib qhov tsim nyog los yaug lub plab nrog mis nyuj, tov ntawm hmoov txhuv nplej siab los yog gelatin thiab muab ib qho kev nqus.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj tsis siv tshuaj nrog iodine kom tshem tawm cov tawv nqaij mob. Xab npum thiab anionic tus neeg sawv cev neutralize qhov kev txiav txim ntawm cov yeeb tshuaj. Inorganic acid ntsev tsim cov tshuaj sib txuas nrog 0,5% chlorhexidine.
Analogs
Miramistin thiab hydrogen peroxide, uas yog analogues ntawm chlorhexidine nyob rau hauv cov nqe lus ntawm hom kev ua, nyob rau hauv pawg ntawm antiseptics. Tag nrho cov analogue yog Hexicon.
Miramistin belongs rau cov pab pawg muaj antiseptics, uas yog ib qho piv txwv ntawm chlorhexidine nyob rau hauv cov nqe lus ntawm hom kev ua.
Cov kev mob cia ntawm cov tshuaj Chlorhexidine
Khaws rau hauv qhov chaw qhuav, tsaus, txias.
Txee lub neej ntawm yeeb tshuaj
Nyob ntawm daim ntawv ntau npaum li cas, lub txee lub neej yog tsis ntau dua 2-3 xyoos.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Tsis tas yuav yuav qhov xaj yuav tshuaj.
Chlorhexidine ntau npaum li cas?
Tus nqi ntawm cov tshuaj yog nyob ntawm daim ntawv, ntim, chaw tsim tshuaj paus, cheeb tsam. Tus nqi ntawm cov kev daws teeb meem txawv ntawm 10 txog 200 rubles, kev pub ntxiv - txog 155-208 rubles, tshuaj tsuag - los ntawm 19 rubles rau 100 ml, gel - nyob ntawm qhov muaj pes tsawg leeg.
Chlorhexidine Xyuas
Maxim, 25 xyoo, Kemerovo: "Kuv khaws cov tshuaj Chlorhexidine rau hauv kuv cov tshuaj txhua lub sijhawm. Kuv tsis tsuas yog kho cov qhov txhab thiab qhov nqaij ntuag, siv lawv tom qab chais, tab sis kuj siv rau kev kho khau thiab txhais ceg. Nws pab."
Ilana, hnub nyoog 18 xyoo, Kiev: "Kuv so kuv lub ntsej muag nrog Chlorhexidine tov thaum pob kab ntxau tshwm. Kuv tsis tau ua tiav cov tshuaj. Kuv pom zoo nws rau kuv cov phooj ywg, vim tias nws ua haujlwm nrawm nrawm nrawm. Thiab qhov no yog qhov tseem ceeb rau txhua tus poj niam thiab cov ntxhais uas muaj txaus teeb meem daim tawv nqaij. "
Galina, hnub nyoog 30 xyoo, Moscow: "Txawm hais tias nws yog ib qho kev kho mob pheej yig, nws zoo heev. Kuv tau coj Chlorhexidine ntau xyoo nrog teeb meem nrog caj pas ob leeg hauv tsev thiab tom kuv tus txiv. Nws pab tau sai heev. Txhua 3-4 hnub dhau los. tsis xis nyob hauv qhov ncauj thiab caj pas. "
