Lisinopril ntsiav tshuaj muaj cov nyhuv tawm suab antihypertensive. Cov tshuaj no belongs rau ACE inhibitors. Thaum siv cov tshuaj no, nws tsim nyog ua raws li cov lus qhia rau kev siv thiab kev pom zoo ntawm tus kws kho mob. Qhov no yuav tso cai rau koj kom tau txais cov txiaj ntsig zoo tshaj plaws los ntawm nws txoj kev txais tos thiab zam qhov tshwm sim ntawm kev phiv.
Npe
Lub npe kev lag luam ntawm cov tshuaj no hauv Russia thiab thoob ntiaj teb cov npe tsis yog npe (INN) yog Lisinopril. Hauv Latin, cov tshuaj hu ua Lisinopril.
Lisinopril ntsiav tshuaj muaj cov nyhuv tawm suab antihypertensive.
ATX
Hauv kev thoob ntiaj teb anatomical thiab kho tshuaj sib cais tshuaj lom neeg, cov tshuaj no muaj tus lej C09AA03.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog npaj rau kev tswj hwm qhov ncauj. Nws muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj puag ncig, uas txawv hauv cov xim ntawm nyias raws li qhov tsuas tshuaj. Cov tshuaj ntawm ib koob ntawm 2.5 mg muaj xim nplua nuj txiv kab ntxwv. Qhov koob tshuaj 5 mg yog lub teeb xim txiv kab ntxwv. Cov koob tshuaj ntawm 10 mg yog xim paj yeeb. Cov tshuaj ntawm ib koob tshuaj 20 mg muaj lub plhaub dawb.
Lub hauv paus tseem ceeb ntawm cov tshuaj no yog lisinopril dihydrate. Cov nkauj kuj tseem ntxiv cov tshuaj xws li:
- attracts;
- calcium hydrogen phosphate;
- hmoov txhuv nplej siab;
- magnesium stearate;
- silicon dioxide;
- hlau oxide;
- microcrystalline cellulose;
- croscarmellose sodium;
- talc;
- calcium hydrogen phosphate;
- lactose monohydrate.
Cov kab ke ntawm cov tshuaj ntxiv yog nyob ntawm qhov chaw tsim khoom. Cov ntsiav tshuaj muaj nyob rau hauv blisters ntawm 10-14 pcs.
Pharmacological kev txiav txim
Cov tshuaj yog txo cov kev ua haujlwm ntawm cov angiotensin-hloov pauv enzyme. Qhov no ua rau muaj kev txo qis hauv aldosterone thiab nce ntxiv ntawm endogenous vasodilating GHGs. Vim qhov no, tsis tsuas yog ntshav siab ruaj khov, tab sis kuj muaj lub nra rau ntawm myocardium txo qis thiab nws qhov kev tawm tsam rau kev cuam tshuam tsis zoo yog nce. Noj tshuaj lisinopril ua kom qis dua cov leeg ntshav khov. Lub siab nyob rau hauv cov hlab ntsha uas nyob hauv lub ntsws ua kom tsawg dua. Kev tsim kho cov hlab ntaws hloov kho.
Nrog kev siv zog, cov tshuaj yeeb tshuaj yog txwv los ntawm renin-angiotensin system ntawm lub plawv. Qhov no tso cai rau koj los tiv thaiv qhov pom ntawm myocardial hypertrophy. Cov hlab plawv nyhuv ntawm cov tshuaj txo cov kev pheej hmoo ntawm kev tuag sai thiab thaiv cov hlab ntshav khiav ntshav. Kev siv cov lisinopril tiv thaiv qhov pib ntawm ischemia thiab rov ua myocardial infarction. Qhov no nce lub neej ntawm cov neeg mob.
Kev siv cov lisinopril tiv thaiv qhov pib ntawm ischemia thiab rov ua myocardial infarction.
Cov Tshuaj Pharmacokinetics
Qhov nqus tus nqi tom qab tswj tau li ntawm 25%. Cov tshuaj yeeb dej caw yuav luag tsis khi rau cov ntshav protein. Kev kho kom haum pib tshwm sim tom qab li 1 teev. Qhov siab tshaj plaws tau nce mus txog tsuas yog 6-7 teev. Nyob rau lub sijhawm no, lub cuab yeej muaj qhov ua tau ntau tshaj plaws. Lub sijhawm tiv thaiv ntawm kev tuav cov tshuaj nquag hauv lub cev yog 24 teev. Biotransformation tsis tshwm sim, yog li ntawd, cov tshuaj yog tawm los ntawm lub raum tsis hloov pauv. Ib nrab-lub neej tshwm sim hauv tsuas yog 12 teev.
Dab tsi yog nws rau?
Kev txais ntawm lisinopril yog qhia txog kev mob ntshav siab arterial. Cov tshuaj tuaj yeem siv los ua cov cuab yeej kho mob ywj pheej, los yog ua ke nrog lwm cov tshuaj uas txo cov ntshav siab.
Raws li ib feem ntawm kev sib xyaw ua ke, kev noj Lisinopril ua ke nrog cov tshuaj diuretics, suav nrog xws li Indapamide, tau lees paub hauv lub plawv tsis ua haujlwm.
Lub sijhawm teem ntawm Lisinopril tau muaj kev cuam tshuam zoo rau myocardial infarction, yog tias cov tshuaj tau sau tseg rau thawj hnub tom qab tawm tsam. Cov tshuaj tso cai rau koj los pab txhawb kev ua haujlwm hauv lub siab thiab zam kom tsis txhob mob siab rau txoj kev rov sab laug.
Qhov taw qhia rau kev siv cov tshuaj lisinopril kuj tseem yog nephropathy mob ntshav qab zib. Hauv cov kabmob no, nws tsis yog siv los kho kom ntshav nce siab, tabsis tseem yuav txo cov albuminuria hauv cov neeg mob insulin.
Cov Yuav Tsum Muaj
Cov tshuaj no tuaj yeem siv tsis tau los kho tus neeg mob siab rau qhov ua txhaum ntawm nws ib leeg. Kev siv cov tshuaj no tsis raug txwv rau cov neeg mob uas muaj sia nyob hloov raum. Cov kev mob uas noj Lisinopril tsis pom zoo suav nrog:
- raum leeg ntshav hlab ntsha;
- lub raum tsis ua haujlwm;
- hyperkalemia
- arterial hypotension;
- pathology ntawm cov nqaij sib txuas;
- Quincke's edema;
- mob hlwb pob txha tsis ua haujlwm;
- mob gout
- cerebrovascular tsis txaus ntseeg;
- hyperuricemia
- kev cuam tshuam rau lub plawv, tiv thaiv cov ntshav tawm;
- collagenosis.
Hauv cov xwm txheej no, txawm tias kev siv nrog huab ceev faj ntawm Lisinopril tuaj yeem ua rau lub txim uas tsis muaj kev cia siab.
Yuav ua li cas noj lisinopril?
Tsis tas yuav muab cov tshuaj tso rau hauv tus nplaig lossis yaj. Cov ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj thiab muab ntxuav nrog me me ntawm cov dej. Cov tshuaj no yog pom los ntawm kev ua ntev ntev, yog li koj yuav tsum tau noj nws ib hnub ib zaug. Kev siv cov tshuaj yuav tsum tau ua ke.
Nrog rau cov qauv tseem ceeb ntawm kev kub siab thiab tawg, qib pib tsis ntau tshaj 10 mg.
Yog tias tsim nyog, txhawm rau tswj cov ntshav siab li qub, cov koob tshuaj yuav nce ntxiv rau 20-30 mg ib hnub twg.
Qhov tshuaj yuav tsum tsis pub tshaj 40 mg ib hnub.
Hauv daim ntawv uas mob ntsig txog lub plawv tsis ua haujlwm, qhov pib kis yog 2.5 mg. Tsuas tshuaj yog nce zuj zus. Qhov tshuaj ntau ntau yog 10 mg rau ib hnub.
Thaum dab tsi siab?
Txawm hais tias muaj me ntsis, tab sis kev mob siab ntshav siab, qhov no yog qhov qhia rau kev noj tshuaj. Kev hloov kho koob tshuaj yog ua kom txog thaum ntshav siab rov zoo li qub.
Lub sijhawm twg?
Yuav kom ua tiav qhov txiaj ntsig yam xav tau ntawm kev txo ntshav siab, cov tshuaj yuav tsum noj thaum sawv ntxov.
Lisinopril ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj thiab muab ntxhua nrog dej me me.
Ua ntej lossis tom qab noj mov
Noj mov tsis cuam tshuam rau kev nqus ntawm cov tshuaj nquag thiab qhov ua tau zoo ntawm cov tshuaj.
Lub sijhawm ntev npaum li cas?
Qhov kev txiav txim tom qab tswj tau li ntawm 18 txog 24 teev.
Lub sijhawm twg yog qhov lees txais?
Lub sijhawm kho nrog lisinopril yog txiav txim siab coj mus rau hauv tus neeg mob kuaj mob thiab cov nyhuv cuam tshuam los ntawm tus neeg tuaj koom nrog kws kho mob.
Noj cov tshuaj rau ntshav qab zib
Nrog nephropathy nyob rau hauv tus neeg insulin-tiv thaiv cov ntshav qab zib, qhov pib yuav tsum tsis pub tshaj 10 mg, tab sis yav tom ntej, raws li kev qhia, nws tuaj yeem nce ntxiv rau 20 mg ib hnub twg. Lub sijhawm kho yog nyob ntawm qhov mob hnyav ntawm tus neeg mob lub.
Sab sij huam
Nyob rau hauv lub xub ntiag ntawm ib tug neeg intolerance mus rau tus neeg lub Cheebtsam ntawm cov tshuaj, kev tsis haum tshuaj yog ua tau. Angioedema ntawm lub ntsej muag, tus nplaig, thiab lwm yam tuaj yeem tsim kho. Lub peev xwm Quincke's edema. Tawm tsam keeb kwm ntawm kev kho mob nrog Lisinopril, qhov tshwm sim ntawm kev phiv tshuaj los ntawm cov mob plab, hematopoiesis, nruab nrab lub paj hlwb, thiab lwm yam.
Kev kho mob txoj hnyuv
Qee zaus, kev noj tshuaj pab tuaj yeem ua rau lub siab tsis qhuav ntawm lub qhov ncauj kab noj hniav. Tej zaum muaj kev hloov pauv hauv saj. Mob plab thiab dyspepsia tau sau tseg.
Hematopoietic plab hnyuv siab raum
Nrog rau kev kho kab mob ntev mus ntev, cov neeg mob uas siv tshuaj yaj yeeb tau tsim muaj anemia. Cov kev mob tshwm sim yog pom los ntawm agranulocytosis, leukopenia thiab thrombocytopenia.
Nruab nrab hauv lub paj hlwb
Muab hais tias cov tshuaj kog nkag mus rau cov ntshav-hlwb teeb meem, txoj kev pheej hmoo ntawm kev phiv los ntawm lub hauv nruab nrab cov hlab ntsha tau tsawg heev. Cov tsos mob tshwm sim muaj xws li kev hloov pauv hloov pauv, tsaug zog pheej tsaug zog, asthenia, nqig ceg qis thaum hmo ntuj.
Los ntawm genitourinary system
Lub sijhawm siv ntev ntawm lisinopril pab txhawb kev ua haujlwm ntawm lub raum. Tej zaum kev txhim kho ntawm anuria, proteuria, proteinuria.
Los ntawm lub tshuab ua pa
Feem ntau, thaum noj Lisinopril, hnoos qhuav tshwm sim li tshwm sim. Muaj qee zaus, yog siv hlab ntsws ua pa thiab txoj siav ua pa.
Ntawm ib sab ntawm daim tawv nqaij
Qhov tshwm sim ntawm daim tawv nqaij tsis tshua pom tshwm. Ua tau khaus, nce rhiab rau tshav ntuj. Alopecia thiab tawm hws yog qhov tsis tshua muaj.
Cov lus qhia tshwj xeeb
Nrog rau kev ceev faj, cov tshuaj yuav tsum raug siv rau kev kho mob ntawm cov neeg uas muaj cerebrovascular tsis txaus thiab mob plawv, vim hais tias nrog cov mob no, kev txo qis hauv cov ntshav siab tuaj yeem ua rau mob plawv. Tus lej ntawm cov mob uas tau pom qhov txawv uas qhov siv ntawm qhov cuab yeej tsis raug pom zoo.
Siv thaum cev xeeb tub thiab lactation
Cev xeeb tub yog qhov tsis sib haum rau kev noj tshuaj lisinopril. Cov tshuaj no tsis muaj qhov tshwm sim mutagenic, tab sis tsub kom kev pheej hmoo ntawm lub neej kev noj qab haus huv. Nyob rau hauv kev cuam tshuam ntawm cov tshuaj nquag, kev txhim kho ntawm oligohydramnios kuj tau pom. Tus menyuam yuav raug ncua sijhawm ossification ntawm cov ntsiab lus ntawm lub pob txha.
Noj cov tshuaj no los ntawm tus poj niam lub sijhawm cev xeeb tub muaj feem ua rau tus menyuam muaj lub raum tsis ua haujlwm, lub cev tsis ua haujlwm, thiab lub ntsws muaj ntshav ntau. Yog tias cov tshuaj kom tsim nyog thaum lub sijhawm pub mis, tus poj niam yuav tsum tsis kam pub mis rau menyuam.
Tshuaj Lisinopril rau Cov Menyuam
Cov tshuaj no tsis raug sau tseg rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Siv rau lub sijhawm qub
Rau cov neeg mob laus, cov koob tshuaj yuav raug xaiv ib tus zuj zus. Nws yog ib qho tsim nyog los tswj kev hloov pauv hauv cov ntshav.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj no nrog kev siv system tuaj yeem ua rau txo qis ntawm kev saib xyuas. Nws txoj kev txais tos tsis txwv tsis pub tsav tsheb, tab sis tus neeg mob yuav tsum tau ceev faj.
Noj ntau dhau
Overdose mob muaj tsawg kawg. Lawv tuaj yeem tshwm sim nrog ib zaug txhaj ntau dua 50 mg. Lub ces qhia ib tug overdose muaj xws li:
- cem quav
- tsaug zog
- tso zis tsis xis nyob;
- txo hauv cov ntshav siab;
- ntxhov siab vim thiab txob taus.
Muab hais tias tsis muaj ib qho tshuaj tiv thaiv rau cov tshuaj nquag ntawm cov tshuaj no, kev kho mob nyob rau hauv cov ntaub ntawv no feem ntau ua rau lub plab zom mov nrog kev siv cov tshuaj pleev plab thiab tshuaj nqus. Cov kev ntsuas txuas ntxiv yog tsom rau tshem tawm cov tsos mob tshwm sim.
Kev cuam tshuam nrog lwm yam tshuaj
Cov neeg mob ntshav qab zib mellitus lossis lub raum tsis ua haujlwm, kev siv lisinopril tib txhij yog sib kis vim tias qhov kev pheej hmoo siab ntawm kev ua mob hyperkalemia thiab ua ntej tuag.
Cov tshuaj noj nrog cov tshuaj loog kom zoo yuav ua rau cov ntshav nce siab.
Tsis txhob siv cov tshuaj tiv thaiv ACE no nrog kev siv tshuaj tiv thaiv kev puas tsuaj thiab triceclic antidepressants.
Kev siv ntawm lisinopril nrog estramustine thiab baclofen tsis pom zoo. Tib lub sij hawm cov thawj coj ua rau muaj qhov tshwm sim ntawm kev phiv loj heev. Kev siv tshuaj sib xyaw nrog lisinopril nrog cov tshuaj uas yog pab pawg pawg ntawm gliptins tsis pom zoo.
Nrog saib xyuas
Nrog rau kev tswj hwm tib lub sij hawm ntawm cov tshuaj uas tsis yog tshuaj steroidal, diuretics thiab cov tshuaj muaj poov tshuaj nrog Lisinopril, cov nyhuv ntawm tom kawg tsis muaj zog. Qhov ACE inhibitor no tuaj yeem txhim kho cov nyhuv ntawm cov tshuaj hypoglycemic, yog li thaum sib koom ua ke, koj yuav tsum tswj ntshav qab zib kom tsawg. Kev tswj hwm ib txhij ntawm cov beta-blockers nrog lisinopril txhim kho cov nyhuv tom qab.
Cawv tau zoo
Thaum noj cov tshuaj lisinopril, kev haus cawv yuav tsum zam. Kev siv tshuaj ib leeg ntawm cov tshuaj yeeb thiab dej cawv tuaj yeem ua rau mob ntshav qis.
Analogs
Cov analogues ntawm Lisinopril, uas cov tshuaj no feem ntau hloov nrog, yog:
- Enalapril.
- Txhawb.
- Anaprilin.
- Losartan.
- Ramipril.
- Bisoprolol.
- Moxonidine.
- Captopril.
- Pheej Yig.
- Diroton.
Qhov hloov ntawm Lisinopril nrog nws cov tshuaj analogue yog raug xaj los ntawm kws kho mob yog tias tus neeg mob muaj qee tus neeg tsis tshua mob siab thiab muaj kev phiv loj heev.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj no raug faib hauv khw muag tshuaj yam tsis muaj kws kho mob sau tseg.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Kev yuav ntawm khw muag tshuaj pub rau ib tus neeg yuav tshuaj.
Tus nqi ntawm lisinopril
Tus nqi ntawm cov tshuaj lom zem ntau nyob ntawm qhov ntau npaum li cas, cov naj npawb ntawm cov ntsiav tshuaj hauv ib pob thiab cov tuam txhab tsim khoom. Tus nqi ntawm Lisinopril Avant (Ukraine) 5 mg yog los ntawm 65 txog 70 rubles. Ib qho tshuaj uas nrog koob tshuaj 10 mg yuav raug nqi txij li 62 txog 330 rubles. Cov tshuaj nrog ib koob tshuaj 20 mg nqi ntawm 170 txog 420 rubles.
Cia rau cov neeg mob rau cov tshuaj
Qhov zoo tshaj plaws khaws cia kub ntawm cov tshuaj yog + 25 ° C.
Hnub tas sij hawm
Lub sijhawm tiv thaiv yog 3 xyoo ntawm hnub ua khoom siv.
Cov Neeg Tsim Khoom
Cov kab ke ntawm cov tshuaj ntxiv hauv cov tshuaj muaj pes tsawg leeg nyob ntawm cov tuam txhab thiab lub teb chaws ntawm kev tsim khoom. Cov tshuaj no yog tsim los ntawm cov tuam txhab hauv qab no:
- Avant (Ukraine).
- VERTEX (Russia).
- Teva (Ixayees).
- Stada (kev sib koom ua ke ntawm Lavxias-German).
- Liaj Teb (Belarus).
- Akrikhin (Russia).
- Ratiopharm (Lub Tebchaws Yelemees).
Kev txheeb xyuas txog Lisinopril
Cov tshuaj no tau siv ntau xyoo lawm los kho cov neeg uas muaj ntshav siab, yog li ntawd, nws muaj ntau qhov kev tshuaj xyuas los ntawm cov neeg mob thiab kws kho plawv.
Cov kws kho mob
Svyatoslav, 45 xyoo, Ryazan
Kuv tau ua tus kws kho plawv ntev dua li 15 xyoos. Feem ntau kuv pom zoo kom noj Lisinopril rau cov neeg mob, vim tiascov tshuaj no tsis tshua muaj kev phiv thiab txhawb rau qhov hloov kho me ntsis ntawm tus neeg mob tus mob. Txawm hais tias siv qhov cuab yeej no rau ib lub sijhawm ntev, qhov ua tau zoo ntawm cov cuab yeej tsis txo qis.
Irina, 38 xyoo, Arkhangelsk
Thaum lub sij hawm nws xyaum, cov kws kho plawv ib zaug ntsib qhov zoo li tshwm sim tsis zoo los ntawm kev noj Lisinopril. Cov tshuaj tau pom zoo zoo los ntawm lub cev ntawm cov neeg mob feem ntau thiab tib lub sijhawm tso cai rau lub cev ntshav siab li qub.
Tug Tswv
Svetlana, 45 xyoos, Vladivostok
Tau ntev, nws raug kev txom nyem los ntawm cov ntshav siab ntau, thiab tsuas yog tom qab ntawd txiav txim siab hu rau kws kho plawv. Tus kws kho mob tau sau tseg siv cov lisinopril. Cov tshuaj no tau pab heev. Hauv ib lub lis piam Kuv hnov zoo dua.
Vladimir, hnub nyoog 60 xyoo, Moscow
Kuv tau mob tsim kev kub siab rau ntau dua 15 xyoos. Kuv tau sim ntau cov tshuaj ntawm cov lus qhia ntawm tus kws kho plawv. Ntau tshaj 2 xyoos nyob Lisinopril. Nws pab zoo kom tswj tau lub siab, tab sis koj yuav tsum tsis txhob haus cawv thaum siv. Kuv kev sib xyaw ua rau muaj kev ua kom tsis zoo.
Kristina, 58 xyoo, Rostov-on-Don
Kuv tau txuag Lisinopril ntau dua 3 xyoos. Cov tshuaj no tau pab ua kom ntshav nce siab. Nws yog qhov yooj yim uas koj yuav tsum tau coj nws thaum sawv ntxov. Ua ntej ua haujlwm tom qab noj tshais Kuv noj cov tshuaj thiab zoo nyob txhua hnub.
