Cocarnit yog cov kev npaj nyuaj uas muaj cov vitamins B thiab triphosadenine. Siv los kho mob ntshav qab zib polyneuropathy, neuralgia, mob leeg. Nws kuj tseem siv los txhim kho cov metabolism hauv cov kab mob ntawm cov hlab plawv.
ATX
A11DA (Vitamin B1).
Cocarnit yog cov kev npaj nyuaj uas muaj cov vitamins B thiab triphosadenine.
Tso cov ntawv thiab cov nyob ua ke
Lyophilisate rau kev npaj ntawm cov tshuaj ua pinkish, 3 ampoules ntawm 3 ml hauv ib lub pob ntim. 1 ampoule muaj:
- Trifosadenin 10 mg.
- Nicotinamide - 20 mg.
- Cyanocobalamin - 0.5 mg.
- Cocarboxylase - 50 mg.
Cov Cim: glycine 105,8 mg, cov tshuaj tiv thaiv (methyl parahydroxybenzoate - 0.6 mg, propyl parahydroxybenzoate - 0.15 mg). Cov kuab tshuaj: lidocaine hydrochloride - 10 mg, dej rau txhaj - 2 ml.
Pharmacological kev txiav txim
Cov tshuaj yog ib txoj hauv kev uas muaj ob hom vitamins, ib lub coenzyme thiab tshuaj metabolic.
Trifosadenin yog ib qho khoom siv uas muaj cov ntawv loj macroergic uas muab lub zog rau cov leeg hlwb thiab cov leeg khov. Nws muaj hypotensive thiab antiarrhythmic cuam tshuam. Nthuav tawm ntawm cerebral thiab mob ntshav hlab ntsha. Txhim kho cov metabolism hauv cov hlab ntaws.
Trifosadenin yog ib qho khoom siv uas muaj cov ntawv loj macroergic uas muab lub zog rau cov leeg plawv.
Nicotinamide - vitamin PP, yog koom nrog hauv cov txheej txheem hauv lub zog, kev hloov pauv ntawm Krebs phaum. Txhim kho cov carbohydrate thiab protein metabolism, lub cev ua pa. Lowers cov rog.
Cyanocobalamin - vitamin B12. Qhov tsis muaj peev xwm ntawm cov tshuaj no ua rau tus lau qaib tsis ruaj tsis khov, lub cev tsis ua haujlwm ntawm tus txha nqaj qaum thiab cov hlab ntaws ntawm lub paj hlwb. Nws yog cov neeg pub ntshav siab ntxiv ntawm cov pab pawg methyl los txo cov qib homocysteine, uas ua mob rau cov mob plawv. Txhawb nqa kev tsim dua tshiab ntawm tes.
Cocarboxylase yog coenzyme ntawm carboxylase enzyme uas tswj hwm kev sib txuas thiab kev cais tawm ntawm cov pawg carboxyl rau cov kua qaub alpha-keto. Hais txog antihypoxants, tsub kom myocardial tsis kam mus rau oxygen tsis txaus. Txo cov concentration ntawm lactate thiab pyruvate hauv cardiomyocytes thiab lub cev. Koom rau hauv cov synthesis ntawm nucleic acids, proteins, cov rog.
Cov Tshuaj Pharmacokinetics
Trifosadenin tau tawg nyob rau hauv cov hlwb rau hauv phosphates thiab adenosine, uas tau suav nrog hauv cov txheej txheem ntawm kev tsim ntawm ATP qauv rau lub zog xav tau ntawm lub cev, suav nrog cov hlab ntsha cov hlab ntsha thiab lub siab.
Cocarboxylase nkag mus rau hauv cov ntaub so ntswg, muaj nyob hauv cov txheej txheem metabolic, tom qab ntawd decomposes. Cov khoom ua kom qias yog tawm hauv cov zis.
Cyanocobalamin yog thauj los ntawm transcobalamin cov nqaijrog hauv cov ntaub so ntswg, khaws cia feem ntau los ntawm daim siab, los ntawm uas nws yog qee tawm ntawm cov kua tsib. Hloov mus rau 5-deoxyadenosylcobalamin. Kev cog lus tiv thaiv kab mob yog 0.9%. Raug tshem tawm sai tom qab kev tswj hwm hauv tsoom niam txiv. Qhov siab tshaj plaws yog tau tiav ib teev tom qab txhaj tshuaj intramuscular. Kev tshem tawm ib nrab-lub neej yog 500 hnub. Nws yog tawm rau feem ntau los ntawm txoj hnyuv - txog 70-100%, 7-10% tawm hauv lub cev los ntawm lub raum. Nkag mus hauv lub txiv mis, nrog rau niam mis.
Cyanocobalamin tsuas yog khaws cia los ntawm lub siab, los ntawm qhov chaw uas nws yog ib feem zais nrog cov kua tsib.
Nicotinamide muab faib nrawm thoob plaws lub cev. Nws yog metabolized los ntawm daim siab - nicotinamide-N-methylnicotinamide tsim. Kev tshem tawm ib nrab-lub neej yog 1.3 teev. Nws yog tawm los ntawm lub raum, tshem tawm 0.6l / min.
Kev ntsuas rau siv
Nws yog qhia txog kev mob ntshav qab zib neuropathy (goosebumps, mob neurogenic), mob plawv, mob hlab ntsha hlwb, lub sijhawm tom qab rov qab los ntawm mob stroke thiab lub plawv nres, thaum lub sijhawm hloov ischemic tawm tsam, tsaus muag. Cov lus qhia rau kev siv qhia sciatica, radiculitis.
Cov Yuav Tsum Muaj
Nws yog contraindicated nyob rau hauv kev mob siab txog qhov ua yeeb tshuaj, nce ntshav coagulation, cev xeeb tub, lactation, hnub nyoog qis dua 18 xyoo, mob plawv tsis meej, thromboembolism, hemorrhagic mob stroke, obstructive bronchitis hawb pob, mob ntsws, mob rau daim siab, mob siab, exacerbation ntawm peptic rwj los yog duodenal mob.
Koj tsis tuaj yeem siv cov tshuaj rau qhov tsis tuaj yeem tswj hwm kev mob ntshav siab, kev tiv thaiv kev siab ntsws, ua kom ntev ntawm QT ntu, mob plawv rau plawv, poob siab, bradyarrhythmias.
Koj tuaj yeem siv tsis tau cov tshuaj rau kev tswj xyuas qhov kub siab.
Yuav ua li cas noj Cocarnit
Thaum siv cov tshuaj, koj yuav tsum paub yuav tsum noj nws li cas.
Dab tsi yuav yug
Dilute 2 ml ntawm 0.5% (10 mg) lossis 1 ml ntawm 1% lidocaine nrog 1 ml dej rau txhaj.
Noj cov tshuaj rau ntshav qab zib
Qhov kev txhaj tshuaj yog muab tso rau qhov tob hauv qhov leeg. Lub chav kawm yog 9 hnub rau 1 ampoule. Tom qab tshem tawm ntawm tus mob huam mob, kev kho mob txuas ntxiv - hno yog ua txhua 2-3 hnub. Qhov kev kawm yog 3 lub lis piam.
Sab sij huam
Cov tshuaj yuav ua rau muaj kev phiv.
Kev kho mob txoj hnyuv
Xeev siab, ntuav, raws plab - tsis tshua muaj.
Hematopoietic plab hnyuv siab raum
Qhov ntau zuj zus ntawm cov qe ntshav liab, qe ntshav dawb, qe ua kom ntshav khov.
Nruab nrab hauv lub paj hlwb
Kev ua kom zoo siab, mob taub hau, mob loj dua.
Los ntawm ib sab ntawm lub hauv nruab nrab lub paj hlwb, cov kev mob tshwm sim hauv daim ntawv ntawm mob taub hau yog ua tau.
Los ntawm daim tawv nqaij thiab cov nqaij mos
Los ntawm cov tawv nqaij thiab cov nqaij mos ua pob - ua pob ua pob, khaus, liab ntawm daim tawv nqaij, ua ntxau, tawm hws.
Los ntawm lub cev tiv thaiv kab mob
Quincke's edema, khaus, tawm pob.
Ntawm ib sab ntawm lub siab
Arrhythmia, tachy thiab bradycardia, mob hauv siab, txo qis siab.
Kev ua xua
Anaphylactic kev poob siab, tawv nqaij ua pob.
Tus neeg mob yuav tuaj yeem ua xua raws hom tawv nqaij.
Cov lus qhia tshwj xeeb
Kev kho mob nrog cov tshuaj yuav tsum tau nrog kev kho mob ntshav qab zib mellitus nrog kev pab ntawm hypoglycemic tshuaj. Yog tias cov tsos mob hnyav zuj zus lossis tsis muaj cov kev hloov pauv kom zoo, tus qauv kho yuav raug kho.
Cov tshuaj yog siv tam sim tom qab npaj. Nws yuav tsum muaj cov xim liab dawb. Thaum nws hloov pauv, cov yeeb tshuaj tsis tuaj yeem siv.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov kev mob tshwm sim yog ua tau - kiv taub hau, tsis hnov qab. Thaum lawv tshwm sim, koj tsis tuaj yeem tsav tsheb thiab cov txheej txheem nyuaj.
Cov kev mob tshwm sim yog ua tau - kiv taub hau, tsis hnov qab.
Siv thaum cev xeeb tub thiab lactation
Contraindicated. Thaum noj cov tshuaj, lawv tsis kam noj.
Cockarnit ntau npaum rau cov menyuam yaus
Cov tshuaj yog contraindicated kom txog thaum muaj hnub nyoog 18 xyoo.
Siv rau lub sijhawm qub
Koob tshuaj yuav tsis haum.
Noj ntau dhau
Vim tias cov ntsiab lus ntawm cov vitamins PP nrog rau kev siv ntev, cov tshuaj yuav ua rau lub siab ua rau lub siab rog vim muaj cov pab pawg tsis muaj methyl. Nrog kev noj tshuaj ntau dhau ntawm cyanocobalamin, qib ntawm folic acid txo.
Kev cuam tshuam nrog lwm yam tshuaj
Cyanocobalamin yog sib xyaw nrog cov vitamins B1, B2, B6, folic, ascorbic acid, hnyav hlau (De-nol, Cisplatin), cawv.
Cyanocobalamin yog txuam tsis tau nrog haus cawv.
Nrog rau kev siv thooj txhij ntawm cov tshuaj biguanides (Metformin) nrog cov tshuaj uas muaj cov tshuaj tiv thaiv tsis muaj qabzib, tshuaj tua kab mob aminoglycoside, salicylates, potassium, colchicine, anticonvulsants, qhov nqus ntawm vitamin B12 tsawg dua.
Txhawm rau kom tsis txhob hypercoagulation, koj tsis tuaj yeem siv nrog cov tshuaj uas ua rau cov ntshav viscosity.
Cyanocobalamin tsis tau chloramphenicol.
Txhim kho cov nyhuv vasodilating ntawm dipyridamole.
Purines - Caffeine, Theophylline - antagonists ntawm cov tshuaj.
Thaum siv nrog plawv glycosides, qhov kev pheej hmoo ntawm cov kev mob tshwm sim nce ntxiv.
Nicotinamide txhim kho cov nyhuv ntawm cov tshuaj tiv thaiv kev ntxhov siab, sedative thiab txo cov tshuaj siab
Xanthinol nicotinate txo cov nyhuv ntawm cov tshuaj.
Chaw tsim tshuaj paus
Ntiaj Teb Kev Kho Mob Txwv.
Analogs
Tsis muaj cov nyiaj uas muaj cov khoom siv sib luag ua ke. Txawm li cas los xij, muaj cov tshuaj metabolic - sodium adenosine triphosphate, cocarboxylase, nicotinic acid ntsiav tshuaj, cyanocobalamin.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Tso tawm los ntawm kev kho mob. Sau B.
Nqe rau Cocarnith
Tus nqi rau 3 ampoules yog 636 rubles.
Cia rau cov mob ntawm cov yeeb tshuaj Kokarnit
Khaws rau hauv qhov chaw qhuav ntawm qhov kub ntawm + 15 ... + 25 ° С.
Hnub tas sij hawm
3 xyoos Qhov hnyav yog 4 xyoos.
Xyuas txog Kokarnit
Nastya
Cov tshuaj tsis pheej yig, tab sis qhov mob nrog radiculitis tshem tawm zoo kawg nkaus. Raug hno 12 hno.
Catherine V.
Ntshav qab zib Hom 2 yog ib tug mob hnyav heev. Nws ua tau nws tus kheej hauv qhov mob hauv caj npab thiab txhais ceg. Dhau qhov kawg ntawm 3 lub lis piam. Cov tsos mob polyneuropathy poob qis. Nws tau rais los mus taug kev yooj yim dua.
Peter
Kuv mob nrog tus mob ntshav qab zib hom 2 thiab mob qog ntshav qab zib. Tus kws kho mob tau sau ntawv txhaj tshuaj rau txhua txhua hnub nrog ib ampoule kom tus mob ploj mus. Kuv tau raug nkaug sijhawm 5 hnub, kuv txoj kev noj qab haus huv tau zoo tuaj, kuv qhov mob ntawm kuv txhais tes tau yooj yim dua. Txawm tias lub siab poob qis me ntsis thiab lub siab mob dhau los ua tsawg dua.
