Gliformin Prolong yog ib hom tshuaj siv los kho ntshav qab zib hom 2.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Metformin.
ATX
ATX Code: A10BA02.
Gliformin Prolong yog ib hom tshuaj siv los kho ntshav qab zib hom 2.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Cov kaus poom ua cov yeeb yaj kiab-xaum thiab muaj cov nyhuv ua kom ntev.
Cov xim ntawm lub plhaub nws txawv ntawm daj los rau lub teeb daj. Cov ntsiab lus sab hauv yog dawb nrog cov nplej me me ntawm daj. Cov ntsiav tshuaj muaj biconvex oval duab.
Cov khoom siv tseem ceeb yog metformin hydrochloride. Cov tshuaj muaj cov tshuaj tivthaiv:
- methyl acrylate thiab ethyl acrylate ua copolymer;
- hypromellose;
- microcrystalline cellulose;
- silicon dioxide.
Cov khoom xyaw ntawm lub plhaub suav nrog talc, glycerol, khoom noj khoom haus xim. Cov ntsiav tshuaj tau ntim rau hauv cov kaus poom yas lossis lam fwj ntawm 30 lossis 60 pcs. Ntim sab nraud ua los ntawm cardboard.
Pharmacological kev txiav txim
Lub ntsiab tivthaiv cov ntsiab lus gluconeogenesis thiab tiv thaiv kev tsim ntawm fatty acids. Cov kev siv ntawm lipid peroxidation txo. Yuav pab txo cov ntshav nyob hauv ntshav qabzib.
Qhov rhiab ntawm peripheral insulin receptors nce nrog cov tshuaj.
Tsis cuam tshuam rau cov kua dej hauv lub zais. Lub ntsiab tivthaiv hloov cov chaw muag tshuaj ntawm cov tshuaj insulin pub dawb, thiab tseem txhim kho kev thauj khoom ntawm cov cell ua haujlwm.
Metformin pab txhim kho glycogen ua ke thaum ua kom qeeb li qhov nqus nqus ntawm cov piam thaj los ntawm cov hnyuv.
Kev nquag ua haujlwm ntxiv txhim kho cov khoom fibrinolytic ntawm cov ntshav.
Tus nqi ntawm cov triglycerides, noo thiab tsis txaus cov rog rog tau txo.
Tawm tsam cov keeb kwm yav dhau los ntawm kev noj cov tshuaj, tus neeg mob lub cev hnyav thiab pib qeeb.
Cov Tshuaj Pharmacokinetics
Thaum noj, cov tshuaj nqus tawm los ntawm cov hnyuv maj mam. Qhov siab tshaj plaws yog tau tiav 2-3 teev tom qab noj tshuaj. Bioavailability yog 60%. Cov khoom ua kom nquag plias tsis yog yuav los ntawm cov ntshav ntshav albumin thiab muab nqus sai sai los ntawm cov qog ntawm lub cev. Cov tshuaj feem ntau ua ke nyob rau hauv cov ntaub so ntswg ntawm lub raum, mob siab thiab salivary qog.
Tsis muaj pluas noj hauv lub siab. Nws yog tso tawm kom pom tsis hloov pauv ntawm lub zog tso. Ib nrab-lub neej ntawm ntev ntev glyformin yog los ntawm 2 txog 6 teev.
Kev ntsuas rau siv
Metformin yog qhov tsim tawm rau kev kho mob rau cov ntshav qab zib tsis yog insulin-mellitus nrog kev noj zaub mov tsis txaus thiab kev tawm dag zog hauv cov neeg mob rog dhau.
Hauv cov neeg laus, nws yog siv ob qho tib si nyias thiab muaj kev sib xyaw nrog lwm tus kab mob hypoglycemic.
Hauv cov menyuam yaus hnub nyoog tshaj 10 xyoo, nws tuaj yeem siv ob qho tib si sib xyaw thiab siv sib xyaw ua ke nrog insulin.
Cov Yuav Tsum Muaj
Contraindications rau cov tshuaj muaj qhia nyob rau hauv cov lus qhia rau kev siv:
- acidosis mob los sis mob nyhav;
- mob ketoacidosis;
- mob ntshav qab zib coma lossis mob taub hau;
- mob hnyav;
- mob khaub thuas
- lub cev qhuav lossis ua rau lub cev ntuav tawm;
- nrog lub raum kev ua haujlwm nrog qhov txo qis hauv lub raum lim dej rau 60 ml ib feeb lossis tsawg dua;
- lub plawv tsis ua haujlwm lossis mob myocardial infarction;
- lwm yam kab mob nrog cov pa oxygen tshaib plab ntawm cov hlwb;
- mob hnyav ethanol lom;
- cawv ntev ntev;
- kev siv ntawm iodine-muaj qhov tsis sib thooj rau radiography lossis xaj tomography ntawm cov hlab ntsha, zais zis thiab lub plab.
- ib tug neeg nkhaus lub cev mus rau qhov tseem ceeb lossis ntu ntawm cov tshuaj.
Nrog saib xyuas
Cov neeg mob hnub nyoog ntau dua 60 xyoo uas tau tawm dag zog lub cev ntau dua muaj qhov pheej hmoo ntau dua ntawm kev tsim mob lactic acidosis.
Thaum lub sijhawm lactation, koj tuaj yeem siv cov tshuaj nyob rau hauv kev saib xyuas ntawm tus kws kho mob.
Yuav noj Glyformin Prolong li cas
Cov ntsiav tshuaj noj noj ntawm qhov ncauj thaum lossis tom qab noj mov nrog qhov dej me me.
Nrog ntshav qab zib
Thaum lub sij hawm tshuaj monotherapy rau hauv cov neeg laus, kev txiav txim siab thawj zaug ntawm cov tshuaj rau ib qhov ncauj tswj hwm yog 500 mg. Tus lej ntawm cov txais tos ib hnub yog los ntawm 1 txog 3.
Qhov siab tshaj plaws uas tau tso cai yog 2 g nyob rau ib hnub. Qhov ntau npaum li cas ntawm cov tshuaj tau muab faib ua 2-3 koob tshuaj.
Cov koob tshuaj nce siab zuj zus hauv ntau lub lis piam.
Qhov ntau npaum li cas ntawm cov piam thaj hauv cov ntshav yog saib xyuas siv cov kev ntsuas, raws li qhov ntsuas, qhov koob tshuaj tau kho.
Cov ntsiav tshuaj noj noj ntawm qhov ncauj thaum lossis tom qab noj mov nrog qhov dej me me.
Sab sij huam
Hauv cov menyuam yaus thiab cov neeg laus, tib cov kev mob tshwm sim thaum siv tshuaj.
Kev kho mob txoj hnyuv
Kev phiv los ntawm cov hnyuv hauv plab tau pom nyob rau thawj lub lim tiam ntawm kev kho, tom qab ntawd dhau. Tej zaum yuav tsim:
- xeev siab
- Kev mob siab;
- ua tsis taus pa;
- ntuav lossis raws plab;
- mob plab.
Tsawg tsawg zaus, tau pom muaj tus kab mob siab rau tshuaj.
Hematopoietic plab hnyuv siab raum
Megaloblastic anemia uas cuam tshuam nrog kev tsis txaus cov vitamins b12 metabolism yuav pib txhim kho.
Los ntawm ib sab ntawm cov metabolism
Muaj kev pheej hmoo ntawm lactic acidosis. Nrog rau siv ntev, cov vitamin b12 tsis muaj peev xwm yuav pib.
Los ntawm genitourinary system
Los ntawm lub zog tawm ntawm kev mob tshwm sim tsis hloov pauv.
Endocrine system
Kev mob hypoglycemia tshwm sim los ntawm kev siv cov koob tsis yog ntawm cov tshuaj.
Kev ua xua
Feem ntau, cov tawv nqaij hloov zuj zus: liab, tawm pob, khaus, ua xua.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tsis cuam tshuam rau cov leeg hlwb. Tsav tsheb tau tso cai thaum kho mob.
Cov lus qhia tshwj xeeb
Cov koob tshuaj yuav tau hloov kho raws li qhov tsim nyog tsis ntau tshaj 1 zaug hauv ib lub lis piam. Thaum ua ke nrog cov tshuaj insulin hauv cov menyuam yaus, kev tswj hwm ntawm cov kws kho mob yuav tsum ua kom tsis txhob mob ntshav qab zib.
Siv thaum cev xeeb tub thiab lactation
Cov ntshav qab zib uas tsis pom qab muaj feem cuam tshuam txog kev loj hlob ntawm qhov tsis ua raws cai hauv plab me nyuam hauv plab. Thaum cev xeeb tub, cov tshuaj tsis pom zoo. Thaum lub sij hawm pub mis niam, tus neeg sawv cev hypoglycemic yog cov ntawv ceeb toom nrog ceev faj.
Noj tshuaj glyformin ntev ntev rau menyuam yaus
Tsis siv los kho menyuam yaus hnub nyoog qis dua 10 xyoo.
Siv rau lub sijhawm qub
Cov neeg mob uas laus dua 60 xyoo yog muaj qhov pheej hmoo ntau dua ntawm tus mob acidosis, yog li, kev saib xyuas ntawm tus kws kho mob yuav tsum tau ua.
Daim ntawv thov rau lub raum khiav tsis zoo
Yog tias tus neeg mob tau mob raum tsis ua haujlwm, cov tshuaj tsis raug siv.
Yog tias tus neeg mob tau mob raum tsis ua haujlwm, cov tshuaj tsis raug siv.
Siv rau lub siab ua haujlwm tsis zoo
Nrog rau daim siab ua haujlwm, nws raug tso cai siv nrog ceev faj, txij li lub ntsiab tivthaiv tsis yog metabolized los ntawm daim siab ua haujlwm.
Noj ntau dhau
Nrog rau kev noj tshuaj ntau dhau, cov tshuaj muaj ntau ntxiv hauv lub raum. Cov kab mob lactic acid hlob tuaj. Ua kom tuag tshwm sim tau. Cov tsos mob hauv qab no yog sau tseg:
- tus ntse txo hauv lub cev kub;
- ntuav
- mob hauv plab;
- leeg thiab cov leeg mob;
- arterial hypotension ua ke nrog qhov txo qis hauv lub plawv dhia;
- pa ceev heev.
Nrog rau qhov nce hauv cov kab mob lactic acid hauv cov ntshav, kiv taub hau, tsaus muag, thiab tsis nco qab yog tau pom.
Yog tias xav tias noj ntau tshaj xav tias qhov tshuaj kho, tso tseg. Tus neeg mob yuav tsum tau coj mus rau hauv tsev kho mob sai li sai tau.
Hemodialysis thiab kev kho mob yam ntxwv tau ua.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev tswj hwm tib lub sij hawm nrog insulin, sulfonamides, cov nyhuv ntawm cov tshuaj hypoglycemic yog kho kom zoo, uas tuaj yeem ua rau kev txhim kho hypoglycemia.
Nrog rau kev siv ua ke nrog cov tshuaj tiv thaiv hormonal, cov tshuaj hormones ntawm qog adrenal los yog lub qog cov thyroid caj pas, cov nyhuv tshuaj tsawg dua.
Voj diuretics ua kom nrawm tshaj tawm ntawm cov khoom tseem ceeb, uas txo cov khoom tsim tawm.
B2-adrenergic stimulants nce ntshav ntxiv ntawm cov ntshav qabzib.
Cimetidine tsub kom cov kua qaub lactic ntau ntxiv. Nrog kev sib xyaw ntawm cov tshuaj, cov kev pheej hmoo ntawm acidosis yog ntau dua.
Nifedipine nce ntxiv qhov nqus ntawm cov tshuaj.
Lub ntsiab tivthaiv ua rau tsis muaj zog ntawm cov tshuaj tiv thaiv kab mob.
Cawv tau zoo
Haus dej cawv ib txhij nrog cov tshuaj tsub kom qhov kev pheej hmoo ntawm lactic acidosis. Nws yog txwv tsis pub haus cawv thaum kho.
Analogs
Cov tshuaj ntawm cov tshuaj yog:
- Formmetin;
- Cov kua nplaum ntev;
- Gliformin Berlin Chemie;
- Ssiofor 1000;
- Hnab Ntim Hnab;
- Metfogama.
Dab tsi yog qhov txawv ntawm Gliformin thiab Gliformin Prolong
Gliformin yog qhov tshuaj ntawm cov tshuaj nrog lub sijhawm luv luv ntawm kev ua. Ib nrab-lub neej yog los ntawm 1.5 txog 4 teev.
Cov nqe lus ntawm lub caij nyoog ntawm Glyformin Prolong Z Lub Tsev Muag Tshuaj
Cov tshuaj yuav muab faib tawm los ntawm cov tshuaj noj.
Glyformin Prolong Nqe
Hauv tebchaws Russia, tus nqi ntawm cov tshuaj pib los ntawm 200 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj yog rau cov pab pawg B. Nws raug tso cai kom khaws cov tshuaj nyob hauv qhov chaw tsaus thiab qhuav ntawm qhov kub ntawm qhov siab tsis tshaj 25 ° C. Khaws tsis ncav cuag ntawm cov menyuam yaus.
Hnub tas sij hawm
Cov tshuaj yog pub kom khaws cia rau 2 xyoos. Hnub ntau lawm tau qhia rau pob.
Gliformin cov khoom tsim tawm ntev
Cov tshuaj no yog tsim los ntawm tsob nroj ntawm Tshuaj nyob rau hauv koom pheej Belarus.
Kev txheeb xyuas txog Gliformin Prolong
Cov tshuaj no tau nrov ntawm ob tus kws kho mob thiab cov neeg mob.
Cov kws kho mob
Olga Belyshova, kws kho mob, Moscow: "Cov tshuaj muab cov ntshav qab zib tsawg zuj zus thiab txhim kho cov mob hlwb."
Egor Smirnov, endocrinologist, Sochi: "Cov tshuaj tsis pom zoo kom siv ib txhij nrog cov thyroid npaj, txij li qhov no qhov cuam tshuam ntawm ob qho tshuaj raug txo."
Cov neeg mob
Elena, hnub nyoog 48 xyoo, St. Petersburg "Kev noj cov tshuaj pab kom cov ntshav qab zib nyob ruaj khov."
Oleg, 35 xyoo, Syzran: "Kuv tau pib noj cov tshuaj xyoo tas los no. Cov piam thaj nyob qis hauv qhov qub."
Poob phaus
Ekaterina, 39 xyoo: "Kuv siv tshuaj ntxiv rau kev noj haus. Rau 3 lub hlis kuv poob 8 kg. Qhov hnyav tsis rov qab los thiab tseem nyob rau theem."
Alexandra, 28 xyoo: "Nrog kev sib txuam tshuaj, kev noj zaub mov zoo thiab tawm dag zog, nws txo qhov hnyav los ntawm 72 mus rau 65 kg."
