Neyrolipon yog cov tshuaj uas muaj cov tshuaj antioxidant thiab hepatoprotective thaum siv. Cov tshuaj no yog siv hauv kev kho mob rau kev kho mob thiab tiv thaiv kev tiv thaiv mob polyneuropathy ua rau kev qaug cawv los yog ntshav qab zib. Ntau qhov txhab ntawm cov hlab ntsha ntsig txog kev kho mob vim tias qhov kev txiav txim ntawm thioctic acid, uas muaj txiaj ntsig zoo ntawm cov metabolism ntawm neurons.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Thioctic acid.
Neyrolipon yog cov tshuaj uas muaj cov tshuaj antioxidant thiab hepatoprotective thaum siv.
Hauv Latin - Neurolipon.
ATX
A16AX01.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv 2 daim ntawv cov tshuaj: hauv daim ntawv ntawm tshuaj ntsiav thiab raws li mloog zoo rau kev npaj ntawm cov tshuaj txhaj tshuaj. Pom tau, cov tsiav tshuaj npog nrog lub plhaub gelatin tawv ntawm lub teeb daj Hawj txawm, thiab sab hauv muaj cov hmoov ntxeem tau los ntawm cov pob zeb daj. Chav tsev ntawm kev npaj muaj 300 mg ntawm cov tshuaj nquag - thioctic acid. Raws li cov koomhaum pabcuam hauv kev tsim khoom siv:
- hypromellose;
- magnesium stearate;
- dehydrogenated colloidal silicon dioxide;
- mis nyuj lactose qab zib;
- microcrystalline cellulose.
Lub plhaub sab nraud muaj gelatin, titanium dioxide. Cov xim ntawm cov tshuaj ntsiav yog muab los ntawm ib qho xim daj raws xim hlau oxide.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm tsiav tshuaj.
Faj
Qhov kub siab yog pom tau pom los ntawm cov kua pob tshab uas ntim hauv ampoules ntawm cov iav dub uas muaj ntim ntawm 10 lossis 20 ml. Qhov tshuaj xav tau los npaj tov rau kev txhaj tshuaj rau cov leeg ntshav. Daim ntawv tshuaj rau cov tshuaj muaj zog 30 mg ntawm thioctic acid nyob rau hauv daim ntawv ntawm meglumine thioctate ua cov tshuaj sib xyaw.
Ntawm cov ntu Cheebtsam yog:
- meglutin hauv kev hloov pauv ntawm N-methylglucamine;
- macrogol (polyethylene glycol) 300;
- dej rau kev txhaj tshuaj 1 ml.
Ntawm lub hwj, qhov taw tes tawg yog taw qhia.
Daim ntawv tsis muaj
Cov tshuaj tsis muaj nyob hauv daim ntawv foos, muag tsuas yog hauv cov tshuaj capsule. Qhov no yog vim qhov tseeb tias cov ntsiav tshuaj tsis tuaj yeem muab cov nqi tsim nyog nqus thiab muaj peev xwm txaus ua kom muaj peev xwm ua tiav kom ua tiav txoj kev kho kom zoo.
Pharmacological kev txiav txim
Cov tshuaj nquag ntawm cov tshuaj muaj cov nyhuv ua rau lub cev ntawm lub cev thiab pab ntxuav cov ntaub so ntswg ntawm co toxins. Nyob rau tib lub sijhawm, cov tshuaj tiv thaiv tseem ceeb tiv thaiv cov kab mob siab tiv thaiv lub siab ua rau ntau dhau thiab muaj tshuaj lom los ntawm cov tshuaj.
Cov nquag ua haujlwm ntawm cov tshuaj tiv thaiv lub siab ua haujlwm los ntawm kev thauj mus los thiab ua kom lub cev tsis zoo ntawm cov tshuaj lom neeg.
Thioctic acid yog tsim nyob rau hauv lub cev hauv cov khoom me me, vim tias ib qho tshuaj lom neeg tshuaj lom neeg yuav tsum tau koom nrog hauv oxidative decarboxylation ntawm alpha-keto acids (hauv Krebs cycle). Vim yog lub coenzyme yam ntxwv, thioctacid ua lub luag haujlwm tseem ceeb hauv lub zog hauv lub cev metabolism.
Cov tshuaj lom neeg lub cev ua cov tshuaj tiv thaiv kab mob endogenous uas deactivates thiab ua ib lub complex nrog cov dawb radicals. Ua lub coenzyme muaj nuj nqi hauv kev hloov pauv ntawm cov tshuaj thiab cov khoom sib txuas nrog cov teebmeem antitoxic. Tsis tas li ntawd, alpha lipoic acid muaj peev xwm rov ua lwm yam tshuaj tua kab mob antioxidant, tshwj xeeb tiv thaiv cov keeb kwm ntawm ntshav qab zib mellitus. Hauv cov neeg mob, thaum noj tshuaj, cov tshuaj tiv thaiv insulin tsawg dua, vim tias cov tshuaj lom neeg lub cev tiv thaiv kev puas tsuaj rau cov hlab ntsha tsis zoo.
Cov tshuaj txo cov ntshav plasma concentration ntawm cov piam thaj hauv lub cev thiab inhibits qhov kev tsim ntawm glycogen hauv hepatocytes. Tactic acid koom nrog cov rog thiab roj metabolism, txo cov roj (cholesterol) tag nrho thiab txo cov phom sij atherosclerotic fatty plaques ntawm cov hlab ntsha. Thaum noj Neyrolipona, muaj kev txhim kho rau daim siab ua haujlwm vim cov nyhuv hepatoprotective.
Qhov tshuaj tiv thaiv tsis zoo yog vim muaj txiaj ntsig ntawm cov tshuaj tiv thaiv kev ua si ntawm cov tshuaj lom rau cov neeg mob lub tebchaw lom. Acid nrawm qhov kev puas tsuaj ntawm cov tshuaj lom neeg, ua pa oxygen hom, sib xyaw ntawm cov hlau hnyav, ntsev thiab nrawm lawv cov kev tshem tawm thaum koom nrog mitochondrial cell metabolism.
Cov Tshuaj Pharmacokinetics
Thaum muab tshuaj ntawm qhov ncauj, thioctic acid yog nrawm rau hauv txoj hnyuv kom 100%. Nrog kev noj zaub mov zoo ib yam, tus nqi nqus poob qis. Bioavailability yog 30-60% tom qab thawj zaug nkag los ntawm daim siab ua haujlwm. Yog tias nws nkag mus rau hauv cov hlab ntshav, qhov kev nquag nquag nce mus txog nws qhov siab tshaj plaws hauv 30 feeb.
Thaum muab tshuaj ntawm qhov ncauj, thioctic acid yog nrawm rau hauv txoj hnyuv kom 100%.
Cov tshuaj yog hloov pauv hauv hepatocytes los ntawm kev ua kom muaj zog thiab muaj qhov tshwm sim oxidative. Thioctic acid thiab nws cov khoom lag luam metabolic tawm hauv lub cev hauv nws daim ntawv qub los ntawm 80-90%. Ib nrab-lub neej yog 25 feeb.
Dab tsi yog xaj tshuaj
Cov tshuaj yog siv los kho thiab tiv thaiv cawv polyneuropathy thiab ntshav qab zib neuropathy.
Cov Yuav Tsum Muaj
Hauv qee qhov tshwj xeeb, cov yeeb tshuaj tsis pom zoo lossis txwv tsis pub siv:
- cov menyuam yaus thiab tub ntxhais hluas hnub nyoog qis dua 18 xyoo;
- lub sij hawm ntawm kev xeeb tub thiab kev xeeb tub;
- nce kev cuam tshuam ntawm cov ntaub so ntswg mus rau cov qauv hauv cov tshuaj;
- hereditary daim ntawv ntawm kev tsis lees paub rau lactose, galactose, tsis muaj lactase thiab malabsorption ntawm monosaccharides hauv lub cev.
Nrog saib xyuas
Ceev faj yog pom zoo rau cov ntshav qab zib mellitus, ulcerative erosive lesions ntawm lub plab thiab duodenum, hyperacid gastritis.
Yuav noj NeroLipone li cas
Thaum muab qhov ncauj, nyob rau hauv daim ntawv ntawm tshuaj ntsiav, nws yuav tsum haus dej haus ntawm cov tshuaj yam tsis muaj kev zom. Cov tshuaj no tau thov rau ntawm lub plab khoob 30 feeb ua ntej noj mov hauv ib qho tshuaj txhua hnub ntawm 300-600 mg. Lub sijhawm kho mob yog txiav txim los ntawm tus kws kho mob tshwj xeeb. Hauv cov kab mob loj, nws raug nquahu kom pib nrog niam txiv kev siv cov tshuaj.
Kev siv tshuaj tiv thaiv yog ua tawm 600 mg ib hnub rau ib tus neeg laus. Nws yog ib qho tsim nyog los tswj lub Txoj kev lis ntshav qeeb - tsis ntau tshaj 50 mg ib feeb. Txhawm rau npaj cov tshuaj kua dej tawm, nws yog ib qho tsim nyog kom yaj 600 mg ntawm cov concentrate hauv 50-250 ml ntawm 0.9% isotonic sodium chloride tov. Cov qhia yog nqa tawm 1 lub sijhawm hauv ib hnub. Nyob rau hauv cov mob hnyav ntawm cov kabmob, qhov koob tshuaj yog nce rau 1200 mg. Cov tshuaj npaj tau yuav tsum muaj kev tiv thaiv los ntawm kev cuam tshuam rau lub hnub thiab ultraviolet hluav taws xob.
Lub sijhawm kho yog 2-4 lub lis piam, tom qab ntawd lawv hloov mus rau kev saib xyuas kev kho mob (noj tshuaj tsiav tshuaj) nrog tshuaj ntawm 300-600 mg ib hnub rau 1-3 lub hlis. Txhawm rau kho cov nyhuv tshuaj, nws raug tso cai rov ua dua 2 zaug nyob rau ib xyoo.
Lub sijhawm kho mob yog txiav txim los ntawm tus kws kho mob tshwj xeeb.
Nrog ntshav qab zib
Nyob rau hauv kev muaj ntshav qab zib, nws yog ib qho tsim nyog yuav tsum tau soj ntsuam kom tsis tu ncua qib qab zib hauv lub cev. Hauv qee kis tshwj xeeb, koj yuav tsum sab laj nrog koj tus kws kho mob txog kev kho cov tshuaj hypoglycemic rau kev tiv thaiv cov ntshav qog ntshav qab zib.
Thioctic acid ua rau kev hloov pauv hauv lub plasma concentration ntawm pyruvic acid hauv cov ntshav.
Kev phiv los ntawm neuroleipone
| Lub cev thiab cov tshuab los ntawm qhov ua txhaum cai tshwm sim | Sab sij huam |
| Lub plab zom mov |
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| Kev ua xua tsis haum |
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| Lwm yam |
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Raws li kev phiv, daim tawv nqaij ua pob tshwm tuaj.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tsis cuam tshuam rau kev ua haujlwm ntawm lub hauv nruab nrab thiab peripheral poob siab. Hauv lub sijhawm ntawm kev kho mob nrog Neyrolipon, kev cuam tshuam nrog cov txheej txheem nyuaj, tsav tsheb thiab lwm yam haujlwm uas yuav tsum muaj kev kub siab thiab ceev ntawm cov tshuaj tiv thaiv raug tso cai.
Cov lus qhia tshwj xeeb
Cov neeg mob ntxim rau qhov tshwm sim ntawm anaphylactic kev hloov kho, ua ntej pib siv tshuaj kho, nws raug nquahu kom ua qhov tsis haum rau kev zam rau kev zam rau cov txheej txheem tshuaj lom neeg lub cev.
Siv rau lub sijhawm qub
Cov tshuaj tsis muaj qhov cuam tshuam ncaj qha rau lub plawv kev mob plawv thiab lub plawv tsis txaus, tab sis vim yog muaj qhov tsis zoo tshwm sim rau tib neeg uas muaj hnub nyoog tshaj 50 xyoo thaum siv tshuaj kho mob, ceeb toom yog qhia thaum siv cov tshuaj. Kev kho ntxiv ntawm cov koob tshuaj txhua hnub tsis tas yuav ua haujlwm.
Cov neeg uas muaj hnub nyoog tshaj 50 xyoo thaum siv tshuaj kho mob tau qhia rau kev tawm dag zog thaum siv cov tshuaj.
Tshaj Tawm Neurolypone rau menyuam yaus
Cov yeeb tshuaj txwv tsis pub rau siv kom txog 18 xyoo, vim tias tsis muaj cov ntaub ntawv los ntawm kev tshawb fawb txaus txog kev muaj peev xwm ntawm tshuaj lom neeg ntawm thioctic acid los cuam tshuam rau tib neeg kev loj hlob thiab kev loj hlob hauv menyuam yaus thiab thaum tiav hluas.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj lom neeg nquag Neyrolipona yog contraindicated rau siv thaum lub caij embryonic txoj kev loj hlob, li cov tshuaj sib xyaw ua ke tuaj yeem nkag mus rau hauv qhov chaw nres lub cev thiab cuam tshuam kev tso ntawm cov kabmob thiab cov tshuab. Kev noj tshuaj tsuas yog coj tawm hauv cov xwm txheej tseem ceeb, thaum muaj kev phom sij rau lub neej ntawm tus poj niam cev xeeb tub ntau dua qhov muaj feem ntawm kev muaj tus kab mob pathologies hauv lub cev xeeb tub.
Tsis txhob xaj tshuaj thaum HB.
Daim ntawv thov rau lub raum khiav tsis zoo
Ceev faj yog qhia nyob rau hauv muaj muaj mob los sis mob raum tsis zoo, raws li 80-90% ntawm cov tshuaj tawm hauv lub cev vim glomerular pom thiab tubular tso pa tawm.
Ceev faj yog qhia nyob rau hauv muaj muaj mob los yog mob raum tsis ua hauj lwm.
Siv rau lub siab ua haujlwm tsis zoo
Nyob rau hauv kev ua txhaum loj ntawm kev ua haujlwm ntawm lub siab ua haujlwm, nws yog ib qho tsim nyog yuav tsum tau sau tshuaj ib hnub ua kom tsim nyog thiab ua tib zoo saib xyuas kev kho mob thaum noj cov tshuaj. Cov tshuaj muaj cov nyhuv hepatoprotective, tab sis cov tshuaj tiv thaiv nquag muaj qee yam nyob hauv hepatocytes.
Nrog rau kev ua kom nruab nrab thiab me me muaj kev puas tsuaj, ib qho ntxiv tshuaj kho ntxiv tsis tas yuav ua.
Kev siv tshuaj ntau dua ntawm neuroleipone
Nrog kev quav yeeb tshuaj, cov tsos mob ntawm kev siv tshuaj ntau dhau tshwm sim:
- xeev siab
- gagging;
- mob taub hau thiab kiv taub hau;
- mob leeg;
- kev cuam tshuam ntawm acid-puag thiab dej-electrolyte tshuav nyiaj, uas yog nrog los ntawm cov kab mob lactic acidosis;
- mob ntshav khov ntau ntxiv thiab nce hauv prothrombin sijhawm;
- kev loj hlob tau ntawm hypoglycemic coma thiab tuag.
Xeev siab yog ib ntawm cov cim ntawm kev overdose.
Yog tias tus neeg mob tau noj tshuaj ntau dua li 4 teev dhau los, tus neeg raug tsim txom yuav tsum ua kom ntuav, yaug lub plab thiab muab cov khoom nqus (ua kom hluav ncaig ntxiv) txhawm rau tiv thaiv kev nqus ntxiv ntawm Neuro lipon. Thaum tsis muaj ib yam khoom tshwj xeeb dab tsi, kev kho mob hauv chaw kho mob yog txhawm rau tshem tawm cov tsos mob tshaj plaws.
Hemodialysis thiab tshuaj ntxuav ntshav tso kua mis yog qhov tsis muaj txiaj ntsig, vim tias cov tshuaj sib txuas tsis khi rau cov roj ntsha plasma.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv Neyrolipon tib lub sijhawm nrog lwm cov tshuaj, cov tshuaj tiv thaiv tau pom hauv qab no:
- Tawm tsam keeb kwm ntawm thioctic acid, nws txhim kho txoj kev kho (tiv thaiv nyhuv) ntawm glucocorticosteroids.
- Qhov ua tau zoo ntawm Cisplatin yog txo qis.
- Cov tshuaj Ethanol uas muaj cov tshuaj ua kom lub zog tsis muaj zog ntawm neuroleptone.
- Ua ke nrog cov tshuaj insulin, tshuaj hypoglycemic rau kev tswj hwm ntawm qhov ncauj, synergism yog pom (cov tshuaj ua kom muaj txiaj ntsig ntawm cov tshuaj pharmacological ntawm ib leeg).
- Cov tshuaj lom neeg cov tshuaj Neyrolipona ua rau lub cev tsis sib haum nrog cov hlau, yog li cov tshuaj tsis pom zoo kom coj los ua ke nrog cov hlau uas muaj cov sawv cev (npaj nrog muaj cov hlau nplaum, hlau, calcium ntsev). Lub sijhawm nruab nrab ntawm kev noj tshuaj yuav tsum yog tsawg kawg 2 teev
Cawv tau zoo
Txais kev haus dej caw thaum kho nrog Neyroliponom yog txwv tsis pub. Kev haus dej cawv ethyl ua rau lub zog kho tsis tau zoo ntawm cov tshuaj thiab txhim kho kev lom rau cov kab mob siab.
Txais kev haus dej caw thaum kho nrog Neyroliponom yog txwv tsis pub.
Analogs
Cov tshuaj hauv qab no cuam tshuam nrog kev hloov cov txheej txheem rau cov kab mob analogues uas muaj cov txiaj ntsig zoo ib yam ntawm lub cev:
- Pob Tsuas;
- Berlition 300 thiab 600 tsim los ntawm Berlin-Chemie, Lub Tebchaws Yelemees;
- Corilip Neo;
- Lipoic acid;
- Lipothioxone;
- Oktolipen;
- Thiogamma;
- Thioctacid 600.
Nws tsis pom zoo kom ua txoj kev ywj pheej hloov mus rau kev siv lwm cov tshuaj. Ua ntej hloov cov tshuaj, sab laj nrog koj tus kws kho mob yog qhov yuav tsum tau.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj yog muag los ntawm tshuaj.
Cov tshuaj yog muag los ntawm tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Tsis yog.
Nqi rau neuroleipone
Tus nqi nruab nrab ntawm cov tshuaj ntsiav hauv Lavxias (10 daim txhua nyob rau hauv cov hlwv pob, 3 lub hlwv hauv lub thawv ntawv) yog 250 rubles, rau lub raj mis nrog mloog zoo, los ntawm 170 (rau 10 ml ampoules) txog 360 rubles. (hauv ib ntim ntawm 20 ml).
Cia rau cov neeg mob rau cov tshuaj
Nws raug nquahu kom muab cov tshuaj nyob hauv qhov chaw qhuav, txwv tsis pub menyuam yaus thiab tiv thaiv tshav ntuj, ntawm qhov kub txog + 25 ° C.
Hnub tas sij hawm
5 xyoos txij li hnub tso. Nws yog txwv tsis pub noj cov tshuaj tom qab hnub tas sij hawm qhia ntawm pob.
Chaw tsim tshuaj paus
PJSC Farmak, Ukraine.
Kev txheeb xyuas txog neuroleptone
Eugene Iskorostinsky, kws kho mob, Rostov-on-Don
Kuv xav txog ntawm cov tsiav tshuaj thiab mloog zoo Neyrolipona zoo thiab muaj txiaj ntsig zoo alpha-lipoic acid. Kuv nquag siv cov tshuaj hauv kuv cov chaw kuaj mob. Kuv xaiv cov neeg mob txhawm rau txhim kho qhov rhiab heev ntawm cov hlab ntsha hauv qhov txhab ntawm qhov hlab ntsha hlwb, tshwj xeeb tiv thaiv ntshav qab zib mellitus thiab mob erectile kawg. Kuv nyiam tias kev siv tshuaj ntev ntev yog qhov ua tau, thiab muaj kev xyaum tsis muaj kev phiv tshuaj.
Ekaterina Morozova, 25 xyoo, Arkhangelsk
Cov tshuaj kho mob rau tus kab mob ntshav qab zib polyneuropathy. Kuv tau noj 2 tshuaj ntsiav nyob rau hauv ib zaug nyob rau hauv kev sib txuas nrog cov lus qhia rau kev siv tshuaj. Nws tus mob zoo dua, qab zib rov qab rau qub. Thaum mob, Kuv ploj qhov mob rhiab (txawm tias qhov hnov zoo ntawm cov ntiv tes ploj), tab sis thaum kuv tau noj cov tshuaj, qhov kev xav rov qab - tsis sai, tsis pub dhau 2 hlis. Hauv thawj lub lis piam, Kuv xav kom tsis txhob kho vim tias muaj txiaj ntsig qeeb, tab sis tom qab sab laj nrog tus kws kho mob kuv pom tias qhov no tsis zoo. Tsis muaj kev fab tshuaj dabtsi lossis lwm yam kev phiv thaum kho.
