Clopidogrel C3 yog tshuaj yeeb tshuaj ntawm tshuaj tiv thaiv kev ua si. Nws yog siv rau hauv kev kho mob ntawm cov kab mob ntawm cov hlab plawv system, uas yog tus cwj pwm los ntawm kev tsim cov ntshav txhaws.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Clopidrogel.
Clopidogrel C3 - yog siv rau hauv kev kho mob ntawm cov kab mob ntawm cov hlab plawv, uas yog tus cwj pwm los ntawm kev tsim cov ntshav txhaws.
ATX
B01AC04.
Tso cov ntawv thiab cov nyob ua ke
Cov ntsiav tshuaj dawb nrog zas daj, xim. Lub ntsiab nquag khoom sib xyaw yog clopidrogel bisulfate. Ib ntsiav tshuaj muaj 75 mg ntawm lub ntsiab feem. Cov tshuaj ntxiv: pob kws hmoov txhuv, lactose monohydrate, calcium stearate, titanium dioxide, microcrystalline cellulose.
1 lub thawv muaj 1 lossis 2 pob ntawm 10 ntsiav tshuaj.
Pharmacological kev txiav txim
Cov nquag metabolite ntawm clopidogrel yog ib qho inhibitor ntawm platelet aggregation (gluing ua ke ntau platelet hlwb, uas ua rau tsim muaj lub plab zais), siv ceev xwmphem. Nws muaj cov nyhuv ua haujlwm rau cov roj ntsha txhim kho txoj hlab ntshav, txhais tau tias nthuav cov roj ntsha ntawm cov hlab ntshav, thiaj li txhim kho cov ntshav kev.
Clopidogrel C3 muaj cov nyhuv ua haujlwm rau cov roj ntsha txhim kho lub plawv, uas txhais tau tias nthuav cov roj ntsha cov hlab ntshav, uas txhim kho cov ntshav kev ntshav.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog nqus sai sai los ntawm cov hnyuv hauv plab ntawm lub plab zom mov. Cov metabolism ntawm cov feem ntawm cov tshuaj tshwm sim nyob rau hauv cov ntaub so ntswg ntawm daim siab. Kev Tshem Yog nqa 50% los ntawm lub raum nrog zis, li 46% yog tawm hauv cov hnyuv nrog quav.
Kev ntsuas rau siv
Raws li prophylactic kom tiv thaiv cov teeb meem hauv cov teeb meem nram no:
- myocardial infarction;
- ischemic mob stroke;
- peripheral leeg leeg occlusion;
- mob hlab ntsha tawg;
- angina pectoris.
Cov tshuaj yog tawm rau cov neeg mob atrial fibrillation, nyob rau hauv qhov muaj kev pheej hmoo ntawm cov ntshav txhaws. Ua raws li qhov mob hnyav ntawm cov chaw kuaj mob, nws yog siv cov tshuaj ywj siab los yog ua ke nrog acetylsalicylic acid.
Cov Yuav Tsum Muaj
Nws raug txwv tsis pub coj mus rau cov xwm txheej zoo li no:
- tsis qaug rau tus neeg cov tshuaj ntawm cov tshuaj;
- daim siab ua haujlwm siab;
- mob rwj, nrog rau qhov pom ntawm cov ntshav sab hauv;
- mob ntshav khov intracranial hemorrhage.
Lub hnub nyoog txwv qis dua 18 xyoo. Cov tshuaj muaj lactose. Yog tias tus neeg mob tau txais tus mob tsis haum mis, nws raug txwv tsis pub noj tshuaj (vim tias muaj kev pheej hmoo siab tshaj plaws ntawm kev tsim cov kev mob tshwm sim).
Nrog saib xyuas
Kev tshuaj xyuas tas li ntawm lub xeev ntawm kev noj qab haus huv yog xav tau (ua kev soj ntsuam tas li thiab soj ntsuam kuaj ntsuas) thaum lub sijhawm kho nrog clopidogrel C3 rau cov neeg mob uas yog cov mob hauv qab no:
- mob me thiab mob hnyav daim siab ua haujlwm;
- hloov haujlwm;
- kev tsim kho tshuab, kev raug mob ntawm cov plab hnyuv siab raum;
- cov kab mob nyob rau hauv uas muaj kev pheej hmoo siab los ntshav.
Yuav ua li cas noj clopidogrel C3?
Cov lus qhia muab kev qhia dav dav txog kev noj tshuaj. Rau cov neeg mob laus - 75 mg 1 zaug nyob rau ib hnub. Cov tshuaj tuaj yeem noj tau tsis hais tus noj mov.
Cov tshuaj tuaj yeem noj tau tsis hais tus noj mov.
Kev kho mob ntawm cov mob ntshav ntawm lub cev, tsis txaus ntseeg angina thiab mob plawv yuav tsum tau pib nrog ib koob tshuaj 300 mg ntawm clopidogrel. On thib ob thiab hnub tom qab ntawm kev kho mob, qhov tsuas tshuaj yog 75 mg.
Nrog rau kev tswj fwm nrog Aspirin, kev noj tshuaj ntawm acetylsalicylic acid yog 100 mg. Kev noj tshuaj ntau dua ntawm Aspirin tuaj yeem ua rau ntshav los ntshav.
Mob myocardial infarction: mob thawj zaug - chaw thau khoom 300 mg, tom qab ntawv 75 mg. Lub chav kawm ntawm kev kho mob yog tsawg kawg 1 hlis.
Nrog ntshav qab zib
Koob tshuaj yuav tsis haum. Qhov ntau npaum li cas yog 75 mg rau ib hnub, chav kawm ntawm kev kho mob yog tas mus li nrog kev pheej hmoo siab ntawm thrombophlebitis.
Phiv Cop clopidogrel C3
Cov kev mob tshwm sim feem ntau suav nrog: mob hauv siab, pom tshwm zoo ib yam li mob khaub thuas. Tsis tshua muaj: kev siv tshuaj bronchospasm, kev txhim kho ntawm txoj kev phiv tshuaj anaphylactic.
Ntawm ib feem ntawm cov khoom hauv nruab nrog kev pom
Tsis tshua muaj: mob ntshav ntswg, kev txhim kho ntawm cov mob txha cajqwm.
Los ntawm cov leeg nqaij thiab pob txha sib txuas
Myalgia, mob caj dab, mob leeg ntshav, mob caj pas.
Kev kho mob txoj hnyuv
Mob ntshav hauv lub cev hauv plab zom mov, tso quav - mob raws plab, mob plab. Tsawg dua: kev loj hlob ntawm duodenal rwj thiab mob plab, xeev siab thiab ntuav, tsam plab. Tsis tshua muaj neeg muaj: kev los ntshav hnyav nrog kev pheej hmoo siab tuag, cov tsos ntawm tus mob pancreatitis, ulcerative lossis lymphocytic colitis.
Hematopoietic plab hnyuv siab raum
Leukopenia, mob heev ntawm thrombocytopenia, theem hnyav tshaj plaws ntawm neutropenia.
Nruab nrab hauv lub paj hlwb
Tsis tshua muaj: kev mob ntshav hauv intracranial, uas tuaj yeem ua rau tuag. Kev mob taub hau ib sij ib zaug, kiv taub hau, hloov raws saj.
Los ntawm cov kab mob zis
Kev tsim tawm ntawm hematuria, glomerulonephritis, kev nce ntawm creatinine concentration.
Los ntawm lub tshuab ua pa
Feem ntau muaj qhov ntswg los ntshav, feem ntau tsis tshua muaj mob - bronchospasm, interstitial type pneumonitis, los ntshav hauv lub ntsws, cov tsos ntawm cov ntshav hauv cov qaub ncaug.
Ntawm ib sab ntawm daim tawv nqaij
Nquag cov nyom tawm ntawm daim tawv nqaij: los ntshav hauv qab daim tawv nqaij. Tsis tshua muaj: ua pob rau ntawm daim tawv nqaij, khaus, qhov tshwm sim ntawm purpura. Tsis tshua muaj neeg pom: angioedema type edema, cov tsos ntawm urticaria thiab mob pob txha tsis haum, erythema ntawm ntau daim foos. Cov teeb meem tsis tshua muaj tshwm sim: kev loj hlob ntawm Stevens-Johnson syndrome, yam tshuaj lom lom yam ua kom tsis haum, liab liab.
Los ntawm genitourinary system
Tsis tshua muaj: hematuria. Tsis tshua muaj neeg pom: cov tsos ntawm hypercreatininemia lossis glomerulonephritis.
Los ntawm cov hlab plawv system
Cov tsos ntawm hematomas, tsis tshua muaj: txoj kev los ntshav, nrhiav pom ntawm kev los ntshav ntev thaum phais, txo ntshav siab.
Kev ua xua
Ua pob rau ntawm daim tawv nqaij, Quincke's edema, hom mob hematological, piv txwv li, cov tsos ntawm neutropenia thiab thrombocytopenia.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tsis cuam tshuam rau qhov kev mloog zoo thiab ceev nrawm, los yog cov nyhuv no tsis txaus ntseeg. Yog li kev noj tshuaj tsis yog ib qho nyuaj rau tsav tsheb thiab ua haujlwm nrog cov txheej txheem nyuaj.
Cov lus qhia tshwj xeeb
Yog tias tsim nyog, nqa tawm txoj kev npaj phais mob, noj Clopidogrel C3 yuav tsum tso tseg 1 lub lis piam ua ntej kev teem sijhawm ua haujlwm. Yog tias tus neeg mob tau sau tshuaj rau nws, nws yuav tsum qhia tus kws kho mob tias nws noj clopidogrel.
Tus kws kho mob, thaum sau daim ntawv yuav tshuaj, yuav tsum piav qhia rau tus neeg mob tias ib qho kev los ntshav yuav nres ntev dua, yog li rau kev tshwm sim ntawm atypical los ntshav, tus neeg mob yuav tsum hu rau lub tsev kho mob sai.
Thaum lub sij hawm kho tag nrho nrog clopidogrel C3, nws yog qhov tsim nyog los tswj theem ntawm platelets.
Hauv cov neeg mob uas lub siab pathologies nrog kev siv ntev ntawm clopidogrel C3, muaj qhov pheej hmoo siab ntawm kev mob hemorrhagic hom diathesis.
Cov tshuaj tsis pom zoo rau kev siv los ntawm cov neeg mob nyob rau hauv ntau dua 7 hnub tau dhau los lawm txij li mob ntshav ischemic. Hauv qee qhov tsis tshua muaj tshwm sim, tab sis thrombocytopenic purpura zoo nkaus li. Ib qhov kev mob tshwm sim tuaj yeem tshwm sim nrog kev siv tshuaj ntev, thiab tom qab kev kho lub sijhawm luv luv.
Yog tias tus neeg mob tsis nco qab koob tshuaj ntxiv, thiab tsawg dua 12 teev tau dhau mus txij li thaum tsis noj tshuaj ntxiv, noj ntau npaum li cas, koob tshuaj ntxiv raug noj nyob rau hauv lub sijhawm ib txwm. Yog tias ntau dua 12 teev dhau los, cov tshuaj raug noj nyob rau lub sijhawm ib txwm, qhov tshuaj tsis ntau ntxiv.
Siv rau lub sijhawm qub
Yuav tsum tsis txhob txhaj rau kev kho kom haum. Hauv kev mob ntshav sai myocardial infarction, nws tsim nyog tso tseg thawj zaug kev txhaj tshuaj ntawm 300 mg thiab noj tshuaj tam sim ntawd ntawm kev noj tshuaj ntawm 75 mg rau ib hnub.
Tshaj tawm Clopidogrel C3 rau menyuam yaus
Cov kev tshawb fawb hais txog kev nyab xeeb ntawm kev siv tshuaj rau hauv cov menyuam tseem tsis tau ua. Vim kev nyab xeeb, vim qhov ntxim li muaj cov tsos mob tshwm sim, cov tshuaj tsis tau teev rau cov neeg muaj hnub nyoog 18 xyoo rov hauv.
Siv thaum cev xeeb tub thiab lactation
Cov ntaub ntawv hais txog kev noj cov clopidogrel C3 los ntawm cov poj niam lub sijhawm cev xeeb tub thiab thaum pub niam mis rau noj yog tsis muaj. Hauv kev hais txog qhov no, cov tshuaj tsis raug txwv rau cov pawg no ntawm cov neeg mob.
Siv rau lub siab ua haujlwm tsis zoo
Tsis tas yuav txhaj qhov tshuaj rau txhua tus.
Noj tshuaj ntau ntawm clopidogrel C3
Cov tsos mob: lub caij nyoog los ntshav nrog kev txhim kho ntawm qhov teeb meem. Cov tshuaj no tsis muaj ib qho tshuaj tua tshwj xeeb. Txoj kev kho yog muaj txoj kev kho kom tsis txhob los ntshav. Txhawm rau kom tsis txhob muaj lub cim ntawm kev haus dhau thiab ua rau qhov xwm txheej ntawm tus neeg mob, platelet pawg tau nchuav.
Kev cuam tshuam nrog lwm yam tshuaj
Qee qhov kev sib xyaw ua ke xav tau kev saib xyuas ntxiv:
- Kev siv yooj yim nrog Warfarin nce lub sijhawm los ntshav thiab nws siv.
- Cov tshuaj aspirin: Nws muaj kev pheej hmoo siab los ntshav yog tias acetylsalicylic acid tau noj nyob rau hauv cov koob tshuaj ntau dua li tshuaj tua kabmob.
- Heparin nrog clopidogrel tuaj yeem nqa, tab sis nrog kev ceev faj vim tias muaj kev pheej hmoo ntawm kev qhib ntshav khov.
- Kev npaj los ntawm pab pawg ntawm thrombolytics: qhov ntau zaus ntawm kev los ntshav zoo ib yam li cov uas tau pom nyob rau hauv cov neeg mob uas txhaj ib zaug ntawm clopidogrel.
- Nonsteroidal anti-inflammatory drugs: kev tshawb fawb soj ntsuam tau qhia tias kev siv tib lub sijhawm ntawm clopidogrel thiab NSAIDs ua rau muaj kev pheej hmoo ntawm cov ntshav ploj hauv cov plab hnyuv plab hnyuv plab hnyuv. Kuj tsis paub meej tias los ntshav hauv lub zom zaub mov puas ntau. Nonsteroidal anti-inflammatory tshuaj ua ke nrog clopidogrel yog noj nrog kev ceev faj.
Muaj kev nyab xeeb sib xyaw nrog clopidogrel Nifedipine, Atenolol, Cimetidine, Phenobarbital, Digoxin, Phenytoin, ib pawg calcium calcium blockers.
Cawv tau zoo
Nws yog txwv tsis pub nqa dej cawv thaum kho nrog clopidogrel.
Analogs
Cov tshuaj pauv yog: Plavix, Zilt, Trombo ACC, Atherocard, Ntab, Lopigrol, Klopilet.
Dab tsi yog qhov txawv ntawm clopidogrel C3 thiab clopidogrel?
Tsis muaj qhov sib txawv ntawm cov tshuaj. Cov no yog ob qho yeeb tshuaj nrog zoo ib yam muaj pes tsawg leeg thiab spectrum ntawm kev nqis tes ua, ua los ntawm cov tuam txhab tshuaj sib txawv.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Daim ntawv yuav tshuaj.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Tsis yog.
Tus nqi ntawm clopidogrel C3
Tus nqi (Russia) yog los ntawm 400 rubles.
Cia rau cov neeg mob rau cov tshuaj
Qhov kev tswj hwm kub tsis siab tshaj 25 ° C. Hauv qhov chaw uas tsis muaj hnub ci.
Hnub tas sij hawm
2 xyoos
Chaw tsim tshuaj paus
Russia, Qaum Teb Hnub Poob, CJSC.
Kev tshuaj xyuas txog clopidogrel C3
Ksenia, 32 xyoo, Tyumen: "Qhov tshuaj no zoo. Clopidogrel C3 tus kws kho mob tau tshaj tawm los ntawm tus kws kho mob rau kuv pog tom qab nws tau mob ntshav ischemic. Cov tshuaj zoo li qee yam li tshuaj aspirin hais txog nws txoj kev ua - nws ua rau cov ntshav txhaws, uas ua rau txo cov ntshav txhaws."
Andrey, hnub nyoog 42 xyoos, Astana: "Kuv tau kho C3 nrog clopidogrel 3 xyoo dhau los. Kuv muaj ntshav qab zib, thiab vim li ntawd qhov tshwm sim ntawm qhov mob ntshav siab yog qhov ntau. Nws yog ib txoj kev kho mob zoo. Kuv tuaj yeem hais tias nws muaj kev cuam tshuam zoo rau tag nrho lub cev, txhim kho ntshav ncig. Kuv haus nws nrog kev kawm ntev ntawm ob peb Ob lub hlis, tom qab ntawd kuv so haujlwm me ntsis thiab pib noj tshuaj dua. Ob xyoos dhau los txij li thaum kuv pib noj cov tshuaj no yooj yim rau kev noj qab haus huv thiab kev noj qab nyob zoo. "
Angela, hnub nyoog 48 xyoo, Kerch: “Peb tau qhia Clopidogrel C3 tom qab ntshav txhaws pom ntawm txhais ceg txhawm rau txoj hlab ntshav ntu. Kuv txhais ceg mob tas li thiab tsis zoo. Cov tshuaj no tsuas cawm kuv xwb. kho tau tag lawm, thiab kuv xav tias tsuas yog kev phais mob yuav pab tau nws pov tseg xwb. Qhov tshuaj kho tau zoo, nws tsuas yog qhov ua tsis tau yog koj tsis tuaj yeem yuav nws yam tsis muaj kws kho mob sau, thiab qhov no tsis yooj yim, yog li kuv yuav tsum tau yuav nws rau yav tom ntej. "
