Amaryl M - txhais tau tias txo qis ntshav piam thaj. Cov tshuaj muaj cov haujlwm ua haujlwm ntau ntxiv, txhim kho cov tshuaj insulin. Muab rau cov neeg mob tus mob ntshav qab zib hom 2 ua ke nrog kev noj zaub mov zoo thiab ua lub neej nquag.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Glimepiride + Metformin.
ATX
A10BD02.
Tso cov ntawv thiab cov nyob ua ke
Daim ntawv tso tawm - ntsiav tshuaj. Cov nquag ua haujlwm hauv cov lus muaj pes tsawg leeg yog gliperide thiab metformin hauv qhov ntau npaum ntawm 1 mg + 250 mg lossis 2 mg + 500 mg.
Amaryl M - txhais tau tias txo qis ntshav piam thaj.
Pharmacological kev txiav txim
Cov cuab yeej muaj qhov ua kom zoo (hypoglycemic). Raws li kev ua haujlwm ntawm cov nquag muaj feem, insulin los ntawm beta hlwb raug tso tawm thiab nkag mus rau hauv cov hlab ntshav. Cov ntaub so ntswg feem ntau ua rau muaj qhov tsis txaus siab rau cov kua dej, qhov txheej txheem ntawm cov kua nplaum tsim los ntawm cov khoom tsis muaj cov khoom noj tau raug tshem tawm, qib LDL thiab triglycerides tsawg dua.
Cov Tshuaj Pharmacokinetics
Pharmacokinetic cov kev tshawb fawb qhia 100% khi ntawm glimepiride rau cov ntshav protein. Nrog kev sib xyaw ua ke, nws txoj kev nqus nws qis me ntsis nqes. Nws tsis nthuav tawm hauv cov nqaij, yog metabolized hauv lub siab nrog kev tsim tawm ntawm 2 metabolites, tawm hauv cov hnyuv thiab cov zis (hauv qhov ua rau lub cev tsis ua haujlwm).
Metformin tau nrawm thiab nrawm. Tsis yog biotransformed. Hauv cov neeg mob uas lub raum tsis ua haujlwm, nws tuaj yeem koom hauv cov ntaub so ntswg. Nws tawm hauv cov zis.
Kev ntsuas rau siv
Cov tshuaj yog tawm rau cov ntshav qab zib hom 2, yog tias tsis muaj cov suab thaj nyob hauv qib nrog kev pab los ntawm kev noj haus thiab ua kom lub cev ua si.
Daim ntawv tso tawm yog cov ntsiav tshuaj, qhov nquag ua haujlwm hauv qhov muaj pes tsawg leeg yog gliperide thiab metformin hauv tshuaj npaum li 1 mg + 250 mg lossis 2 mg + 500 mg.
Cov Yuav Tsum Muaj
Kev txais ntawm cov tshuaj no yog contraindicated nyob rau hauv tej yam kev mob thiab kab mob:
- lub raum tsis ua haujlwm thiab lwm qhov tsis zoo lub raum kev ua haujlwm;
- mob hnyav nrog lub siab ua haujlwm tsis zoo;
- cawv ntev ntev;
- mob ua ntej coma lossis coma;
- yam 1 mob ntshav qab zib mellitus;
- kev fab tshuaj rau sulfonylureas, cov tshuaj ntawm cov tshuaj lossis biguanides, sulfonamides;
- ua pa tsis ua haujlwm;
- cov kab mob ntshav qab zib ketoacidosis, nrog rau qhov mob hnyav thiab mob mus ntev ntawm cov kab mob metabolic acidosis;
- lub plawv tsis ua hauj lwm;
- myocardial infarction;
- lactic acidosis;
- npaws
- muaj qhov pom ntawm kev kis hnyav;
- ntshav tshuaj lom;
- txoj hnyuv nqaij tuag tes tuag taw;
- kev nyuaj siab rau keeb kwm ntawm kev raug mob, kub hnyiab, ua haujlwm nyuaj, tshaib plab;
- ob leeg hnyuv;
- zawv plab
- lom lub cev nrog cawv;
- ua txhaum ntawm kev puas tsuaj ntawm cov mis ua piam thaj;
- hnub nyoog txog 18 xyoo;
- galactosemia;
- lactation thiab cev xeeb tub.
Kev kho yuav tsum tsis txhob pib thaum mob hemodialysis.
Nrog saib xyuas
Rau qee kis, noj cov ntsiav tshuaj nrog ceev faj:
- zaub mov tsis zoo;
- tsis muaj lub cev ua haujlwm;
- cov thyroid kawg;
- piam thaj-6-phosphate dehydrogenase tsis muaj peev xwm;
- muaj cov kab mob uas ua rau cov chav ntshav qab zib hom 2 ua rau cov nyom;
- lub cev ua haujlwm hnyav.
Hauv cov laus laus, koj yuav tsum coj nws raws li kev saib xyuas ntawm tus kws kho mob.
Yuav ua li cas noj Amaryl M
Cov tshuaj rau cov thawj coj ntawm lub qhov ncauj yuav tsum noj nrog zaub mov. Hla kev noj tshuaj yuav tsum tsis txhob ua rau kev nce ntxiv ntau npaum.
Nrog ntshav qab zib
Cov koob tshuaj yog txiav txim los ntawm tus kws kho mob nyob ntawm kev mloog ntawm cov piam thaj hauv cov ntshav. Siv cov tshuaj 1-2 zaug hauv ib hnub. Qhov siab tshaj plaws yog 4 ntsiav tshuaj hauv ib hnub.
Phiv Amarila M
Cov tshuaj muaj kev tiv thaiv zoo, tab sis nyob rau qee qhov tsis tshua muaj peev xwm ua rau muaj kev phiv los ntawm ntau yam kabmob thiab cov kab ke.
Hauv cov ntshav qab zib mellitus, kev muab tshuaj yog txiav txim los ntawm tus kws kho mob nyob ntawm seb cov concentration ntawm cov piam thaj hauv cov ntshav.
Ntawm ib feem ntawm cov plab hnyuv siab raum ntawm lub zeem muag
Muaj qhov tsis zoo yog qhov tsis pom kev zoo vim muaj kev hloov pauv hauv cov concentration ntawm cov piam thaj hauv cov ntshav.
Kev kho mob txoj hnyuv
Cov tsos mob los ntawm tus mob plab zom mov: tsis nco qab, qab plab, tso quav, ntuav, ntuav, mob hauv plab, nce roj ntxiv.
Hematopoietic plab hnyuv siab raum
Kev noj tshuaj pab tuaj yeem ua rau muaj kev txhim kho pancytopenia (kev txo qis ntawm cov khoom tseem ceeb hauv cov ntshav siab), ntxiv rau thrombocytopenia, ntshav tsis txaus thiab mob qog nqaij hlav (leukopenia).
Los ntawm ib sab ntawm cov metabolism
Cov tsos mob tej zaum yuav tshwm sim uas qhia txog kev txo ntshav qabzib hauv lub siab: mob taub hau, kiv taub hau, tawm hws, ntshav siab, tachycardia, leeg tsis tuaj yeem sawv cev, tshee tshee, qaug zog, tsaug zog.
Kev ua xua
Nws muaj qhov urticaria, pob pob. Tsawg tsawg zaus, qhov xwm txheej yog qhov nyuaj los ntawm kev poob siab anaphylactic.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tuaj yeem ua rau muaj kev txhim kho hypoglycemia, yog li ntawd nws tsis pom zoo los tswj cov txheej txheem nyuaj thaum kho.
Cov lus qhia tshwj xeeb
Nrog kev mob raum tsis ua haujlwm thiab mob siab, cov kab mob lactic acid tuaj yeem tshwm sim hauv cov ntshav thiab cov nqaij (lactic acidosis). Nrog rau qhov txo qis hauv lub cev kub, mob plab thiab ua tsis taus pa, koj yuav tsum tsum tsis txhob noj cov tshuaj. Txwv ib ntus kev kho mob ua ntej kev phais mob.
Thaum kho txoj kev kho mob, nws raug nquahu kom saib xyuas cov ntshav qabzib hauv cov ntshav kom tiv thaiv kev txhim kho ntawm hypoglycemia. Qhov tseem ceeb zoo ib yam yog kev tswj hwm kev tswj hwm kev ua kom muaj zog ntawm hemoglobin, creatinine thiab vitamin B12. Txhawb glycemia los ntawm kev tawm dag zog, kev noj haus.
Siv rau lub sijhawm qub
Kev tu yuav tsum tau saib xyuas qhov haujlwm ntawm lub raum.
Khaws Amaril M rau me nyuam yaus
Hauv cov menyuam hnub nyoog qis dua 18 xyoo txwv tsis pub.
Siv thaum cev xeeb tub thiab lactation
Nws yog contraindicated yuav pib kho thaum cev xeeb tub thiab lactation. Kev pub niam mis yuav tsum nres.
Daim ntawv thov rau lub raum khiav tsis zoo
Thaum lub raum ua rau mob tsis zoo thiab nce qib creatinine ntau ntau tsis tau raug kho.
Siv rau lub siab ua haujlwm tsis zoo
Hauv kev ua txhaum loj, lub siab ua haujlwm tsis raug samfwm.
Noj tshuaj ntau dhau ntawm Amaril M
Kev noj tshuaj ntau dhau ua rau cov kev mob tshwm sim tsis zoo thiab muaj kev txhim kho hypoglycemia. Cov tsos mob ntawm kev ntshav qab zib yog nres los ntawm qab zib. Kev kho mob raws qab.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj cuam tshuam nrog lwm cov tshuaj raws li hauv qab no:
- kev siv hluav taws xob ib txhij los yog cov tshuaj tiv thaiv ntawm CYP2C9, tetracyclines, azapropazone, antimicrobial cov neeg ua haujlwm ntawm pawg quinolone, tritokvalin, MAO inhibitors thiab ACE inhibitors, fluconazole, coumarin anticoagulants, probenecid, anabolic steroids, fenfluramopininininininininininininininineinin tritokvalina, beta-blockers, aminosalicylic acid ua rau muaj kev txhim kho hauv cov ntshav qab zib;
- nws yog qhov tsis tsim nyog los ua ke tswj hwm nrog x-ray thiab kev siv cov tshuaj iodine-muaj tshuaj;
- nifedipine thiab furosemide ntxiv rau kev tsub zuj zus ntawm Metformin hauv cov ntshav;
- noj tshuaj histamine H2 receptor blockers, clonidine thiab reserpine tuaj yeem ua rau hyperglycemia lossis hypoglycemia;
- ibuprofen tsis cuam tshuam rau pharmacokinetic cov lus;
- ib qho kev txo qis hauv cov ntshav hauv qog tuaj yeem tshwm sim nyob rau hauv kev cuam tshuam ntawm diuretics, epinephrine, nicotinic acid, acetazolamide, diazoxide, estrogens, rifampicin, barbiturates, sympathomimetics, corticosteroids, laxatives, phenytoin, thyroid hormones.
Ntxiv mus, kev tswj hwm tib lub sij hawm nrog gentamicin yuav tsum zam.
Cawv tau zoo
Ethanol tuaj yeem txhim kho lossis txo cov nyhuv ntawm cov tshuaj. Vim tias qhov kev pheej hmoo ntawm hypoglycemia, concomitant cawv nrog cawv yog contraindicated.
Analogs
Hauv tsev muag tshuaj koj tuaj yeem yuav lwm yam tshuaj hypoglycemic nrog cov tshuaj sib xyaw ua ke:
- Glucovans.
- Glimecomb.
- Galvus Met.
Ua ntej siv, koj yuav tsum sab laj tus kws kho mob txhawm rau tiv thaiv qhov tshwm sim ntawm kev phiv.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Tso tawm los ntawm kev kho mob.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Koj tuaj yeem yuav nws tom qab qhia tshuaj los ntawm kws kho mob.
Hauv tsev muag tshuaj koj tuaj yeem yuav lwm yam tshuaj hypoglycemic nrog kev sib xyaw ua ke, piv txwv li, Glucovans.
Amaryl M Nqe
Tus nqi ntawm kev ntim khoom yog los ntawm 800 txog 900 rubles.
Cia rau cov neeg mob rau cov tshuaj
Khaws cov ntsiav tshuaj hauv qhov chaw tsaus thaum kub txog + 25 ° C.
Hnub tas sij hawm
Txee lub neej yog 3 xyoos.
Chaw tsim tshuaj paus
Handok Pharmaceuticals Co., Ltd., Kaus Lim Kauslim.
Kev txheeb xyuas txog Amarila M
Anna Kazantseva, kws kho mob
Tus txheej txheem ntawm cov tshuaj yog kaw cov poov tshuaj channel thiab qhib cov calcium calcium. Nyob rau tib lub sijhawm, cov tshuaj insulin raug tso tawm tsawg dua li nyob rau hauv kev txiav txim ntawm lwm cov sulfonylurea derivatives. Yog li, qhov pheej hmoo ntawm kev txhim kho hypoglycemia yog txo qis.
Anatoly Romanov, tus kws tshuaj endocrinologist
Cov tshuaj ntawm cov tshuaj ua ke sib txig nrog ib leeg. Cov cuab yeej hypoglycemic ntawm metformin qhia tau nws tus kheej thaum lub sij hawm tso tawm ntawm insulin los ntawm beta hlwb. Metformin txhim kho cov nyhuv ntawm glimepiride thiab ua rau txo qis "tsis zoo" cov roj (cholesterol) hauv cov ntshav thiab triglycerides. Nws yog ib qho tsim nyog yuav tsum tau noj cov tshuaj nrog ceev faj tsam muaj teeb meem ntawm cov thyroid caj pas thiab lub siab ua haujlwm.
Eugene, 38 xyoo
Cov cuab yeej pabcuam pab tswj cov qib qabzib. Kuv noj 1 lub tshuaj rau ib qho khoob khoob thaum sawv ntxov thiab kuv tsis tuaj yeem txhawj txhua hnub. Kuv hloov mus rau kev sib xyaw tshuaj raws li kws kho mob tau hais tseg. Vim tias muaj cov kev mob tshwm sim, vim qhov hloov ntawm cov piam thaj hauv cov ntshav, kev pom kev tsis zoo, qee zaum ntuav. Ntev mus, cov tsos mob ploj mus. Kuv txaus siab rau qhov tshwm sim thiab kuv yuav mus txuas ntxiv txoj kev kho mob.
