Rinsulin P yog siv los kho txhua hom ntshav qab zib. Hom insulin no txawm tsim nyog rau kev kho poj niam cev xeeb tub. Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam nruj ntawm txhua txoj cai rau kev noj tshuaj kom tsis txhob muaj kev txhim kho ntawm cov kev tsis haum siab.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Soluble insulin cim "tib neeg kev tsim kho tshuab."
Rinsulin P yog siv los kho txhua hom ntshav qab zib.
ATX
A10AB01.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov tshuaj tiv thaiv. Cov khoom tseem ceeb yog tib neeg cov tshuaj insulin. 1 ml ntawm cov tshuaj ntshiab muaj 100 IU. Cov khoom siv ntxiv uas muaj nrog: methacrizol, glycerin thiab dej rau kev txhaj tshuaj.
Cov tshuaj raug muag hauv 3 lub ntim loj:
- 5 daim cartridges ntawm cov iav ruaj nrog lub ntim ntawm 3 ml tau muab tso rau hauv lub thawv ntim ntawm tes;
- 5 3 ml cartridges mounted hauv kev txiav txim siab tshwj xeeb uas siv cov koob txhaj tshuaj uas siv rau kev siv rov qab (Rinastra);
- 1 khob lub raj mis nrog ntim ntawm 10 ml.
Txhua daim cartridges thiab lub taub ntim no tau muab tso rau hauv cov thawv roj hmab.
Pharmacological kev txiav txim
Rinsulin yog ib tus neeg sawv cev hypoglycemic, tib neeg insulin, uas tau txais los ntawm kev sib txuas ntawm RNA chains. Vim tias kev sib cuam tshuam ntawm cov tshuaj nquag nrog rau sab nraud receptors ntawm cell cov qog ua ke, ib qho tshwj xeeb insulin-receptor complex yog tsim. Nws pab txhawb rau kev tsa ua yuav luag txhua cov txheej txheem tshwm sim sab hauv lub hlwb. Nws siv kev sib tov ntawm cov enzymes. Cov theem ntawm cov piam thaj hauv cov ntshav yog txo los ntawm kev nce ntxiv nws txoj kev thauj mus los hauv lub siab, ua kom zoo dua cov suab thaj los ntawm cov ntaub so ntswg. Nyob rau tib lub sijhawm, tus nqi ntawm cov kua nplaum nyob hauv lub siab raug txo qis.
Rinsulin yog ib tus neeg sawv cev hypoglycemic, tib neeg insulin, uas tau txais los ntawm kev sib txuas ntawm RNA chains.
Cov Tshuaj Pharmacokinetics
Cov nyhuv ntawm cov tshuaj pib tsis pub dhau ib nrab ib teev tom qab kev tswj hwm subcutaneous. Cov ntsiab lus siab tshaj plaws hauv cov ntshav pom tom qab 3 teev. Kev kho mob nyhuv ntev txog li 8 teev.
Qhov nqus thiab faib tawm ntawm cov tshuaj yog nyob ntawm tus qauv ntawm kev coj ua, qhov chaw txhaj tshuaj, kev siv tshuaj, nrog rau cov concentration ntawm cov ntshiab insulin hauv cov tshuaj yeeb tshuaj. Nws qhov kev rhuav tshem tshwm sim nyob hauv qab ntawm insulinase. Nws yog tawm los ntawm raum pom.
Luv lossis ntev
Xws li cov kua dej ntawm tib neeg yog xa mus rau cov tshuaj tiv thaiv luv luv. Qhov no yog vim tus nqi ntawm kev nqus, nyob ntawm qhov koob tshuaj thiab txoj kev ntawm kev tswj hwm ntawm cov tshuaj sib txuas.
Kev ntsuas rau siv
Muaj ntau tus lej ntawm qhov taw qhia ncaj qha rau kev siv tshuaj ntawm tus neeg insulin. Ntawm lawv yog:
- ntshav qab zib mellitus hauv thawj thiab hom thib ob;
- ntshav qab zib hom 2 rau cov poj niam thaum cev xeeb tub;
- cov xwm txheej ceev hauv cov neeg mob ntshav qab zib, uas nrog kev decompensation ntawm carbohydrate metabolism.
Cov poj niam cev xeeb tub yuav tsum ua raws nraim cov lus qhia ntawm tus kws kho mob poj niam.
Rinsulin P yog tshuaj rau ntshav qab zib mellitus ntawm hom thawj thiab thib ob.
Cov Yuav Tsum Muaj
Direct contraindications rau kev siv ntawm tib neeg cov insulin yog:
- ntshav tshuaj qis;
- hypersensitivity rau ib tug neeg Cheebtsam ntawm cov tshuaj.
Nrog kev ceev faj, Rinsulin yuav tsum tau noj los ntawm cov poj niam cev xeeb tub thiab cov menyuam yaus, tib neeg raug ntau yam kev ua xua tshwm sim.
Yuav noj Rinsulin P li cas
Cov tshuaj yog npaj rau subcutaneous, intramuscular thiab leeg ntshav txhaj tshuaj. Nws yog qhia ib nrab ib teev ua ntej ib pluas noj carbohydrate. Qhov kub ntawm cov tshuaj insulin yuav tsum yog chav sov li ib txwm. Feem ntau, cov tshuaj tau txhaj rau hauv thaj av ntawm thaj chaw ntawm sab xub ntiag ntawm lub plab kab noj hniav. Qee zaum yuav raug txhaj koob npe rau ntawm xwb pwg, ncej puab lossis pob tw.
Txhawm rau txhawm rau tiv thaiv kev txhim kho ntawm lipodystrophy, qhov chaw txhaj tshuaj tau hloov pauv, tab sis tsuas yog nyob rau thaj tsam ib puag ncig zoo ib yam. Nrog kev tswj hwm ntawm subcutaneous, kev saib xyuas yuav tsum tau saib xyuas kom tsis txhob ua mob rau cov hlab ntshav. Tom qab txhaj, qhov chaw txhaj tshuaj nws tus kheej yuav tsum tsis txhob kov, zaws lossis txhuam. Vials yog qhov tsim nyog rau siv tsuas yog tias qhov kev daws teeb meem hauv lawv yog qhov tseeb thiab tsis muaj lub nag lossis daus.
Rau qhov ua kom ntev ntev, nrog rau kev tawm suab luv luv Rinsulin P, Rinsulin NPH ntawm qhov nruab nrab kom siv sij hawm ntev ntawm kev siv tshuaj kho tau siv.
Rau qhov ua kom ntev ntev, Rinsulin NPH siv nrog ua ke nrog luv-yeeb yam Rinsulin P.
Nrog ntshav qab zib
Cov koob tshuaj txhua hnub ntawm cov tshuaj muaj yees yog los ntawm 0.5 txog 1 IU ib 1 kg ntawm tus neeg mob lub cev qhov hnyav. Ib qho tshuaj yog muab tshuaj peb zaug hauv ib hnub. Yog tias muaj qhov xav tau ntawd, ces ntau zaus ntawm kev tswj hwm tau nce mus rau 5 zaug hauv ib hnub. Yog tias qhov koob tshuaj txhua hnub yog ntau dua li 0.6 IU, ces yuav tsum tau txhaj 2 koob, uas tau muab tso rau ntau qhov chaw. Tag nrho cov kev txhaj tshuaj yog ua tiav nrog cov kua insulin tshwj xeeb nrog ib qho nyias tab sis ntev koob uas txuas nrog daim nyias tes ntawm cov koob txhaj tshuaj. Qhov no tsis pub cov kua dej kom muaj zog ntau ntxiv hauv ib qho chaw, thiab cov tshuaj nkag mus tob rau hauv cov nqaij mos.
Phiv los ntawm Rinsulin P
Yog tias koj noj cov tshuaj tsis raug, cov kev mob tshwm sim hauv qab no tuaj yeem tshwm sim:
- ntshav tshuaj qis;
- pallor
- tshee hnyo
- plawv dhia;
- tawm hws ntau dhau;
- Kiv taub hau
- daim tawv nqaij ua pob;
- Quincke's edema;
- o rau lub ntsej muag thiab nqua.
Kev mob ntshav qog hnyav tuaj yeem ua rau txhim kho kev mob hypoglycemic coma. Yog tias tsis nco qab lossis qhov pom ntawm lwm tus tsos mob, koj yuav tsum sab laj nrog kws kho mob.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Koj yuav tsum tau ua tib zoo saib xyuas kev thauj thiab lwm cov txheej txheem nyuaj rau thawj coj ntawm kev siv tshuaj insulin, kev hloov pauv ntawm kev noj tshuaj lossis kev hloov pauv hauv txoj kev ua neej, vim tias txhua yam no cuam tshuam qhov ceev ntawm cov tshuaj tiv thaiv thiab kev xav.
Cov lus qhia tshwj xeeb
Siv cov cuab yeej, nws yog ib qho tseem ceeb kom soj ntsuam cov ntshav qab zib tas li. Hypoglycemia feem ntau ua rau kev noj ntau dhau, hloov pauv ntawm cov tshuaj lossis qhov chaw ntawm nws qhov kev qhia, ua rau lub siab thiab lub raum tsis ua haujlwm. Ib qho kev mob uas zoo sib xws, tshwj xeeb tshaj yog rau cov neeg mob uas muaj thawj hom ntshav qab zib, tuaj yeem ua rau noj ntau npaum li cas lossis tsis raug txhaj tshuaj ntau zaus. Hauv qhov no, tus neeg mob muaj mob dyspeptic, qhov ncauj qhuav thiab tsis hnov tsw ntawm acetone.
Cov koob tshuaj yuav tsum tau sau meej meej rau cov neeg laus laus uas lub raum thiab lub cev tsis ua haujlwm zoo. Nws hloov nrog kev hloov pauv ntawm kev ua si thiab lub cev.
Siv thaum cev xeeb tub thiab lactation
Hom insulin no tuaj yeem siv lub sijhawm thaum cev xeeb tub thiab pub niam mis. Tab sis koj yuav tsum tau saib xyuas tas qib ntawm cov piam thaj. Deterioration ntawm kev ntsuam xyuas yuav tsum tau hloov kho kom sai.
Rinsulin IR tuaj yeem siv thaum cev xeeb tub.
Cawv tau zoo
Tsis txhob siv cov tshuaj txhaj nrog kev haus dej haus cawv. Hauv cov khoom me me, cawv tsis tuaj yeem cuam tshuam kev nqus thiab ua tau zoo, tab sis kev haus cawv yuav ua rau muaj kev rau txim loj.
Noj ntau dhau ntawm Rinsulin P
Nws tsis muaj lub ntsiab lus txhais ntawm kev haus ib qho zuj zus, vim ntau yam tuaj yeem cuam tshuam cov ntshav ntawm cov ntshav qabzib. Qhov ua rau hypoglycemia yog ib qho kev ntxig ntshav hauv ntshav ntau vim kev noj zaub mov zoo lossis ua haujlwm ntawm lub cev. Nws ua rau mob taub hau, tsis meej pem, xeev siab, thiab txawm tias ntuav.
Tus neeg mob tuaj yeem tshem tawm qhov mob ntshav qab zib me me los ntawm kev noj hom piam thaj lossis carbohydrates. Yog tias tus neeg tsis nco qab, nws tau txhaj tshuaj nrog 40% dextrose daws teeb meem thiab glucagon ua ke nrog lossis mus rau hauv cov leeg nqaij.
Kev cuam tshuam nrog lwm yam tshuaj
Hauv ib qho koob txhaj tshuaj, tshuaj noj tau tsuas yog muab nrog ua ke nrog Rinsulin NPH. Tsis txhob sib xyaw cov tshuaj nrog insulins ntawm lwm cov tuam ntxhab.
ACE inhibitors thiab lub qhov ncauj hypoglycemic, beta-blockers, bromocriptine, qee qhov sulfonamides, tshuaj steroids, tetracyclines, ketoconazole, pyridoxine, theophylline thiab lithium npaj tuaj yeem txhim kho cov nyhuv hypoglycemic.
Cov nyhuv hauv lub ntsejmuag tsis muaj zog yog tsis muaj zog los ntawm glucagon, estrogen, tshuaj tiv thaiv qhov ncauj, glucocorticosteroids, qee yam tshuaj hormonal, nrog rau cov tshuaj diuretics, Heparin, Morphine, Nicotine thiab calcium channel blockers.
Analogs
Ntau qhov analogues raug tsim tawm uas zoo ib yam li nws ntawm kev siv tshuaj thiab cov nyhuv kho mob. Feem ntau ntawm lawv yog:
- Actrapid;
- Actrapid NM;
- Insuman Sai Sai;
- Neej Neeg R;
- Yawg Farmasulin;
- Insugen-R;
- Yawg Farmasulin N;
- Tshuaj yaug NPH;
- Insulin Cov Khoom Siv.
Qee yam ntawm lawv yog pheej yig dua thiab pheej yig dua, tab sis kuj tseem muaj tus nqi kim hloov.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Koj tuaj yeem yuav tom khw muag tshuaj lossis nqa hauv kev qhia tshwj xeeb hauv chaw kho mob.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Cov tshuaj no raug faib tawm tsuas yog muaj ntawv tshwj xeeb los ntawm koj tus kws kho mob.
Rinsulin R Nqe
Nrhiav cov tshuaj yog qhov nyuaj. Tus nqi ntawm nws cov analogues sib txawv nyob ntawm thaj av ntawd thiab lub khw muag tshuaj muaj npoo thiab yog: hauv tebchaws Russia - ntawm 250 txog 2750 rubles., Hauv Ukraine - los ntawm 95 txog 1400 UAH. rau kev ntim khoom.
Cia rau cov neeg mob rau cov tshuaj
Khaws rau hauv qhov chaw qhuav thiab tsaus, tsom saib qhov ntsuas kub + 2 ... + 8ºC. Koj tsis tuaj yeem tsau nws. Txav deb ntawm menyuam yaus thiab tsiaj.
Hnub tas sij hawm
2 xyoos txij li hnub muab cov teebmeem no, uas tau hais rau ntawm pob ntawv. Kev siv cov khoom lag luam tom qab lub sijhawm no yog txwv tsis pub siv.
Chaw tsim tshuaj paus
Lub tuam txhab tsim khoom lag luam: OJSC "GEROPHARM-Bio", cheeb tsam Moscow, Obolensk.
Kev tshuaj xyuas txog Rinsulin R
Cov kws kho mob
Elizaveta, 39, tus kws kho mob endocrinologist, St. Petersburg: "Cov tshuaj zoo rau cov neeg mob ntshav qab zib hom 1. Kuv yuav tsis qhia tus poj niam cev xeeb tub, piv nrog qee cov tshuaj tiv thaiv analogues, yuav tsum tau noj ntau dua."
Sergey, hnub nyoog 44 xyoo, endocrinologist: "Hnub no kuv tuaj yeem hais tias qhov tshuaj yuav zoo yog tias nws tuaj yeem nqa tawm yooj yim. Kuv tsuas yog sau ntawv rau Rinsulin NPH lossis lwm yam tshuaj ntxiv."
Cov neeg mob
Anna, 28 xyoo, Voronezh: "Kuv txaus siab rau cov tshuaj, Kuv tau siv nws raws li cov lus qhia. Nws tuaj yeem siv tau yooj yim yam tsis muaj kev pab, rab koob yog nyias, cov lus qhia tsis ua rau tsis xis nyob. Koj tuaj yeem pom nws hauv cov chaw muag tshuaj tshwj xeeb nrog cov tshuaj rau tus mob ntshav qab zib."
Mikhail, 46 xyoo, Moscow: "Nws yog qhov nyuaj nrhiav kev kho. Kuv tau siv Rinsulin NPH rau ib hlis thiab tsis pom muaj tshwm sim. Kuv yuav tsum hloov mus rau lwm lub insulin."
Karina, hnub nyoog 21 xyoo, Kiev: "Rinsulin NPH los txog. Cov tshuaj yog muab tau yooj yim, tsis muaj kev phiv tshuaj ntxiv. Tsuas yog tib qho xwb, tsis txhob chim siab yog tias cov tshuaj tsis pab nyob rau thawj lub lim tiam ntawm kev kho, qib qab zib tau rov qab zoo txij li lub lim tiam thib ob ntawm kev tswj hwm thiab kuv tseem khaws cia. ces. "
