Clopidogrel-Teva yog tshuaj uas txo cov platelet aggregation thiab dilates hlab ntsha. Cov cuab yeej yog siv rau kev kho mob thiab tiv thaiv kab mob plawv.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
INN - Clopidogrel.
Clopidogrel-Teva yog tshuaj uas txo cov platelet aggregation thiab dilates hlab ntsha.
ATX
ATX Code: B01AC04.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog nyob rau hauv daim ntawv ntawm elongated ntsiav tshuaj ntawm lub teeb liab xim. Cov tshuaj yeeb tshuaj yog clopidogrel hydrosulfate (hauv qhov ntau npaum li 75 mg).
Cov muaj tswv yim:
- lactose monohydrate;
- microcrystalline cellulose;
- hyprolosis;
- crospovidone;
- hydrogenated zaub roj ntawm hom I;
- sodium lauryl sulfate.
Lub plhaub zaj duab xis muaj cov khoom siv hauv qab no:
- lactose monohydrate;
- hypromellose 15 cP;
- titanium dioxide;
- macrogol;
- oxide liab thiab daj (hlau ua kom ntom ntom);
- indigo carmine.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj.
Pharmacological kev txiav txim
Cov tshuaj nquag ua haujlwm ntawm cov tshuaj txo cov platelet sib sau ua ke. ADP nucleotides (adenosine diphosphates) zoo li ua kom glycoprotein inhibitors thiab khi rau platelets. Hauv qab ntawm clopidogrel, cov txheej txheem no tau cuam tshuam thiab yog li platelet aggregation (koom nrog) raug txo kom tsawg. Cov kev ua si (PDE) ntawm phosphodiesterase tsis hloov pauv qhov quav.
Qhov ua haujlwm antiplatelet ntawm cov tshuaj siv tau ntev mus txog lub neej kev ua haujlwm ntawm platelets (kwv yees li 7 hnub).
Cov Tshuaj Pharmacokinetics
Thaum noj ntawm qhov ncauj, cov ntsiav tshuaj yuav nqus sai hauv cov hnyuv. Clopidogrel muaj bioavailability siab, tab sis kev hloov pauv tsis muaj txiaj ntsig (qhov no yog yam khoom). Nws yog nyob rau hauv cov ntshav rau ib lub sijhawm luv luv thiab muaj kev cuam tshuam sai sai hauv lub siab nrog kev tsim cov khoom noj ua kom lub zog thiab lub cev tsis ua haujlwm. Tom qab ntawd clopidogrel thiab cov nquag metabolite khi yuav luag txhua nrho rau cov ntshav protein.
1 teev tom qab noj cov tshuaj hauv cov ntshav, qhov siab tshaj plaws ntawm lub zog tsis haum ntawm clopidogrel hauv ntshav, ib qho kev sib txuas ntawm carboxylic acid, tau pom.
Cov tshuaj tau tawm hauv cov zis thiab quav hauv 5 hnub. Kev siv tshuaj lom neeg lub cev yog tawm hauv 16 teev.
Kev ntsuas rau siv
Cov tshuaj yog kws kho rau kev tiv thaiv cov mob plawv hauv cov nram no:
- Myocardial infarction.
- Ischemic mob stroke.
- Mob plawv mob caj dab mob yam tsis muaj nce hauv ntu.
- Thrombosis (siv los ua ke nrog acetylsalicylic acid).
- Thromboembolism.
- Atrial fibrillation.
- Nyob rau hauv muaj contraindications rau siv ntawm anticoagulants ntawm indirect kev txiav txim.
Cov Yuav Tsum Muaj
Cov ntsiav tshuaj txwv tsis pub noj rau cov neeg mob uas lub siab tsis ua haujlwm (mob hnyav), ua rau lub ntsej muag tsis haum tshuaj lossis mob ntshav khov.
Cov txheej txheem tsis huv yog tseem cev xeeb tub, lactation thiab menyuam yaus hnub nyoog qis dua 18 xyoo.
Nrog saib xyuas
Nrog kev ceev faj, cov tshuaj yog tawm rau kev ua haujlwm tsis zoo hauv lub raum (kev tsis txaus nrog creatinine tshem ntawm 5-15 ml / min), muaj ntshav ntau ntxiv (hematuria, menorrhagia), ntxiv rau tom qab kev phais mob, raug mob thiab ua tsis tiav hauv cov kab mob hemostatic.
Hauv kev kho mob ntawm cov neeg mob uas muaj kab mob siab, ib coagulogram tseem ua haujlwm tas li thiab kev ua haujlwm ntawm lub siab yog saib xyuas.
Nrog kev ceev faj, cov tshuaj yog tawm rau kev ua haujlwm hauv lub raum.
Yuav ua li cas noj clopidogrel-teva?
Cov neeg mob uas tau myocardial infarction tau sau tshuaj 75 mg ntawm tshuaj (1 ntsiav tshuaj) hauv ib hnub rau 7-35 hnub. Tom qab mob hlab ntsha tawg, cov tshuaj raug muab hauv tib qho, tab sis chav kho mob tuaj yeem ntev txog rau lub hlis.
Cov neeg mob uas muaj tus mob coronary tsis muaj nce hauv cov qib ST tau hais kom noj 300 mg ib hnub twg yog thawj zaug. Tom qab ntawd cov koob tshuaj yog txo mus rau 75 mg rau ib hnub, tab sis kev sib xyaw ntawm antiplatelet nrog acetylsalicylic acid yog sib xyaw ua ke. Kev Kho Mob yog nqa tawm rau 1 xyoos.
Nrog ntshav qab zib
Hauv cov neeg mob uas mob ntshav qab zib mellitus, feem ntau pom cov platelet sib xyaw yog feem ntau pom. Txog kev tiv thaiv cov mob plawv thiab mob ntsws ua ntshav tawm, 75 mg ntawm clopidogrel-Teva tau sau tseg rau ib hnub.
Lub sijhawm ua haujlwm ntawm cov thawj coj thiab kev noj tshuaj ntawm cov tshuaj Insulin yuav tsum tau txiav txim los ntawm tus kws kho mob, nyob ntawm tus mob ntawm tus neeg mob.
Phiv los ntawm clopidogrel-Teva
Ntawm ib feem ntawm cov plab hnyuv siab raum ntawm lub zeem muag
Ntawm keeb kwm yav dhau los ntawm kev noj cov tshuaj, mob ntshav ntawm lub ntsej muag (lub ntsej muag thiab mob sib txuas) yuav tshwm sim.
Los ntawm cov leeg nqaij thiab pob txha sib txuas
Qhov ua rau tsis zoo rau cov leeg mus txheej txheem ntawm cev yog qhov tsawg. Mob pob txaws, mob pob txaws thiab mob leeg ntshav yog tau.
Cov tshuaj tuaj yeem ua rau kom muaj kev mob plab.
Kev kho mob txoj hnyuv
Cov nyhuv ntawm lub plab zom plab yog ua raws li cov hauv qab no:
- mob plab;
- los ntshav hauv cov hnyuv;
- xeev siab thiab ntuav
- zawv plab
- txhab tawm tsam;
- mob plab zom mov;
- plaub sua;
- kab mob siab;
- pancreatitis
- mob plab
- daim siab ua hauj lwm.
Hematopoietic plab hnyuv siab raum
Los ntawm sab ntawm cov kab ke no tau hais tseg:
- thrombocytopenia;
- leukocytopenia;
- eosinophilia.
Nruab nrab hauv lub paj hlwb
Cov tshuaj yeeb yaj kiab tsis cuam tshuam rau cov leeg poob siab. Muaj qee zaus, mob taub hau, kiv taub hau, thiab feeb tsis meej tshwm sim.
Los ntawm cov kab mob zis
Phiv los ntawm lub plab hnyuv siab raum:
- hematuria;
- glomerulonephritis;
- nce creatinine hauv cov ntshav.
Los ntawm lub tshuab ua pa
Qhov cuam tshuam ntawm cov txheej txheem ua pa:
- taub ntswg;
- pulmonary hemorrhage;
- bronchospasm;
- interstitial pneumonitis mob ntsws.
Los ntawm genitourinary system
Sab dab tsi tsis txhim kho.
Los ntawm cov hlab plawv system
Los ntawm cov hlab plawv yog pom:
- los ntshav
- arterial hypotension;
- vasculitis.
Kev ua xua
Kev tsis haum tshuaj hauv qab no tuaj yeem tshwm sim:
- Quincke's edema;
- ntshiab ntshav mob;
- urticaria;
- khaus
Tawm tsam keeb kwm ntawm kev noj tshuaj, qhov kev tawm tsam tsis haum yuav tshwm sim.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Qee tus neeg mob tau mob taub hau thiab kiv taub hau thaum noj Clopidogrel-Teva. Kev ceev faj yuav tsum siv thaum tswj cov tshuab lossis kev ua haujlwm uas yuav tsum muaj kev kub siab ua haujlwm.
Cov lus qhia tshwj xeeb
Ua ntej kev phais mob, cov tshuaj yuav tsum tsis ua haujlwm ntxiv (5-7 hnub ua ntej kev phais mob) vim qhov muaj feem yuav los ntshav.
Siv rau lub sijhawm qub
Cov tshuaj yog siv los kho cov neeg laus laus. Tab sis qhov no, kev kho mob yog ua tiav yam tsis muaj kev txhaj tshuaj nce qib (ib qho tshuaj sib npaug rau 300 mg) thaum pib kho.
Tshaj tawm Clopidogrel-Teva rau menyuam yaus
Cov tshuaj yog txwv rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Siv thaum cev xeeb tub thiab lactation
Cev xeeb tub thiab pub niam mis yog contraindications rau kev siv ntawm cov tshuaj no.
Koj tuaj yeem siv tsis tau cov tshuaj no thaum cev xeeb tub.
Siv rau lub siab ua haujlwm tsis zoo
Cov neeg mob uas muaj lub siab pathologies (mob ntsws, mob siab tsis ua haujlwm) yog tau cov tshuaj nrog ceev faj. Txhawm rau kom tsis txhob hemorrhage, kev kho mob yuav tsum tau nrog kev saib xyuas kev ua haujlwm ntawm lub siab.
Clopidogrel-Teva Noj Ntau Tshaj
Nrog tib lub qhov ncauj tswj hwm kev noj tshuaj loj (txog li 1050 mg), tsis muaj ib qho tshwm sim hnyav rau lub cev.
Kev siv ntev ntev hauv kev siv ntau ntau tuaj yeem ua rau ntshav los ntshav.
Kev cuam tshuam nrog lwm yam tshuaj
Vim tias txoj kev pheej hmoo los ntshav, nws yog txwv tsis pub noj cov tshuaj no nrog rau cov tshuaj xws li:
- Cov tshuaj Anticoagulants.
- Glycoprotein IIa / IIIb inhibitors.
- NSAIDs.
Qhov ceev faj yuav tsum tau ua ke nrog heparin.
Qhov ceev faj yuav tsum tau ua ke nrog thrombolytics thiab heparin. Nrog tib lub sijhawm siv nrog omeprazole, esomeprazole thiab lwm yam tshuaj tiv thaiv twj tso kua mis, qhov txo qis hauv cov nyhuv antiplatelet tshwm sim.
Cawv tau zoo
Cov tshuaj tsis pom zoo kom ua ke nrog kev haus dej haus cawv. Muaj peev xwm ua txhaum cai ntawm lub cev, ua pov thawj los ntawm ntuav, raws plab, pom tus kheej, kub taub hau, ua tsis taus pa thiab palpitations.
Analogs
Cov tshuaj uas nrov nrog cov nyhuv zoo sib xws yog:
- Lopirel.
- Plavix.
- Sylt.
- Pobtsuas.
- Aggregal.
- Egithromb.
Cov tshuaj nquag ntawm cov analogues no yog clopidogrel.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Raws li cov lus qhia, cov tshuaj yog raug tshuaj.
Clopidogrel-Teva Nqe
Tus nqi ntawm ib pob ntawm 14 ntsiav tshuaj nyob ntawm 290 txog 340 rubles, 28 ntsiav tshuaj - 600-700 rubles.
Cia rau cov neeg mob rau cov tshuaj
Kev khaws cia yuav tsum tau nqa tawm hauv qhov chaw tsaus thaum kub uas tsis tshaj + 25 ° C.
Hnub tas sij hawm
Cov tshuaj no haum rau 2 xyoos.
Chaw tsim tshuaj paus
Chaw Tsim Tshuaj - Teva (Ixayees).
Cov tshuaj yog raug faib tawm los ntawm cov tshuaj noj.
Kev tshuaj xyuas ntawm clopidogrel-Teva
Irina, 42 xyoo, Moscow.
Thaum kuv mus kuaj ntshav, Kuv pom muaj qib theem ntawm cov platelets. Tus kws kho mob tau muab tshuaj clopidogrel. Kuv tau noj cov tshuaj rau 3 lub lis piam, thiab lub platelet suav hauv cov ntshav rov qab zoo li qub.
Alexander, 56 xyoo, Izhevsk.
Kuv pib noj cov tshuaj no raws li kev pom zoo los ntawm kws kho mob tom qab mob stroke. Kuv tau noj nws 2 lub hlis thiab kuv tsis yws txog kuv txoj kev noj qab nyob zoo. Tsis muaj kev mob tshwm sim. Cov tshuaj muaj nqi rau cov nyiaj.
Leonid, hnub nyoog 63 xyoo, Volgograd.
Kuv siv cov tshuaj no txhawm rau tiv thaiv kev mob tom qab kev phais pob txha. Hauv sijhawm tom qab ntu tas, cov tshuaj tau pab tiv thaiv kom ntshav txhaws. Kuv zam nws kev txais nkag zoo, tsis tau ntsib dua qhov tsis zoo.
