Espa-Lipon 600 yog ib cov tshuaj uas muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj los yog txhaj tshuaj. Lub mechanism ntawm kev nqis tes ua thiab cov yam ntxwv pharmacological nyob ntawm cov nyhuv ntawm alpha-lipoic acid, uas yog ib feem ntawm cov tshuaj. Cov tshuaj yog siv los ua ib feem ntawm kev sib xyaw rau kev kho mob ntshav qab zib lossis dej cawv polyneuropathy. Thioctic acid tsis yog raug rau cov menyuam yaus lossis tus pojniam xeeb tub, vim tias tsis muaj ib qho pov thawj ntawm qhov tsis zoo ntawm cov tshuaj nquag ntawm kev txhim kho lub cev.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Thioctic acid.
Lub thoob ntiaj teb uas tsis yog tus tswv cuab lub npe Espa-Lipon yog Thioctic acid.
ATX
A05BA.
Tso cov ntawv thiab cov nyob ua ke
Tus txheej txheem metabolic yog tsim nyob rau hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj thiab hauv daim ntawv ntsiav tshuaj. Hauv rooj plaub tom kawg, cov chav ntawm kev npaj tau them nrog ib zaj yeeb yaj kiab enteric nyias nyias muaj raws li hypromellose, macrogol 6000, titanium dioxide thiab talc. Hauv cov tub ntxhais ntawm cov ntsiav tshuaj yog 600 mg ntawm qhov nquag sib txuas - alpha-lipoic lossis thioctic acid. Txhawm rau txhawm rau txhim kho qhov nqus ntawm cov nquag tivthaiv thiab pab txhawb kev rhuav tshem ntawm txoj hnyuv, cov ntsiav tshuaj daim ntawv ntxiv nrog cov tshuaj pabcuam, xws li:
- microcrystalline cellulose hmoov;
- povidone;
- mis nyuj qab zib;
- silicon dioxide colloidal dehydrated;
- sodium carboxymethyl hmoov txhuv nplej siab;
- magnesium stearate.
Elongated ntsiav tshuaj muaj qhov biconvex duab. Zaj duab xis membrane yog xim daj vim muaj lub quinoline zas ntawm qhov sib txuam ntxoov ntxoo.
Cov tshuaj Espa-Lipon rau kev txhaj tshuaj yog nyob rau hauv iav ampoules, txhua tus muaj 600 mg ntawm ethylene bis ntsev ntawm alpha lipoic acid.
Cov tshuaj txhaj yog nyob rau hauv iav ampoules, txhua tus muaj 600 mg ntawm ethylene bis ntsev ntawm alpha lipoic acid. Cov dej huv yog siv tshuaj hnyav.
Pharmacological kev txiav txim
Alpha lipoic acid txhim kho cov metabolism. Cov nquag ua haujlwm pab txhawb lub zog hauv cov roj hauv lub cev vim qhov oxidation ntawm pyruvic acid thiab alpha-keto acids. Los ntawm cov roj ntsha biochemical, thioctic acid zoo ib yam li kev ua ntawm B vitamins.
Cov tshuaj nquag belongs rau cov tshuaj tiv thaiv kab mob endogenous. Nws koom nrog kev rog thiab carbohydrate metabolism. Alpha-lipoic acid muaj qhov ua kom cov lipid-txo qis, txo cov ntshav muaj roj cholesterol, txhim kho daim siab ua haujlwm thiab txhawb kev nrawm tshem tawm cov co toxins tawm ntawm lub cev. Cov tshuaj normalizes trophic hlab ntsha hlwb.
Cov Tshuaj Pharmacokinetics
Thaum noj ntawm qhov ncauj, alpha lipoic acid nrawm rau hauv txoj hnyuv. Kev sib xyaw ua ke ntawm cov ntsiav tshuaj nrog zaub mov txo qhov nqus ntawm thioctic acid. Bioavailability yog 30-60%. Qhov qes qis ntawm kev nqus ntawm cov tshuaj nquag yog vim yog thawj qhov tshuaj dhau los ntawm hepatocytes, qhov chaw tshuaj lom neeg tshuaj lom neeg yauv pauv hloov.
Qhov kev tivthaiv tau mus txog qhov siab tshaj plaws ntawm cov ntshav hauv cov ntshav tom qab 25-60 feeb. Qhov kev tshem tawm ib nrab-lub neej ua rau 20-50 feeb. Alpha-lipoic acid tawm lub cev los ntawm kev tso zis tawm ntawm 80-90%.
Kev nquag ua haujlwm ntawm Espa-Lipon mus txog nws cov kev xav ntau hauv cov ntshav tom qab 25-60 feeb.
Kev ntsuas rau siv
Cov tshuaj yog siv hauv qhov kev coj ua kho mob kom tshem tawm cov cawv thiab ntshav qab zib neuropathy. Kev txhaj tshuaj rau cov leeg ntshav ntxiv tuaj yeem siv los kho cov kab mob pathological hauv lub siab: mob ntsws, mob ntsig txog mob (mob siab), haus dej cawv lossis siv tshuaj yaj yeeb ua rau hepatocytes. Alpha-lipoic acid tuaj yeem txo tus mob ntawm tus neeg mob thiab pab tshem cov tshuaj lom neeg mob yog tias muaj tshuaj lom hnyav nrog cov hlau ntsev hnyav, nceb lossis tshuaj lom.
Qee qhov xwm txheej, Espa-Lipon siv los ua cov tshuaj lipid-cov tshuaj tiv thaiv cov keeb kwm yav dhau los ntawm vascular atherosclerosis thiab txo cov roj cholesterol. Qhov kawg yog qhov ua rau ntawm kev tsim ntawm atherosclerotic plaques rau ntawm cov hlab ntsha ntawm lub ntsiab thiab peripheral cov hlab ntsha.
Cov Yuav Tsum Muaj
Cov tshuaj yog contraindicated nyob rau hauv lub xub ntiag ntawm hypersensitivity rau yam ntxwv tshuaj ntawm Espa-Lipon, nrog lactose intolerance.
Nrog saib xyuas
Cov tshuaj yuav tsum tau sau tseg nrog kev ceev faj thaum mob siab thiab lub raum tsis ua haujlwm.
Espa-Lipon 600 yuav tsum yog cov kws kho mob ceev faj thaum muaj teeb meem mob siab.
Yuav ua li cas noj Espa-Lipon 600
Kev tswj hwm ntawm qhov ncauj ntawm cov tshuaj yog nqa tawm ib hnub ib zaug, haus 1 ntsiav tshuaj (600 mg) ntawm ib qho kev npliag plab. Nws tsis pom zoo kom siv cov ntsiav tshuaj uas puas lawm, vim hais tias kev siv tshuab ua txhaum cai ntawm cov xuv xim txheej txo qhov kev nqus thiab kev ua haujlwm ntawm alpha lipoic acid. Cov ntsiav tshuaj yog siv los ua kev tiv thaiv kev tiv thaiv lossis tom qab qhov kawg ntawm kev tswj hwm kev coj ntawm cov tshuaj, cov chav kawm uas kav ntev li 2-4 lub lis piam.
Kev kho nrog cov ntsiav tshuaj tsis pub tshaj 3 lub hlis. Hauv qhov tshwj xeeb, qhov nce ntawm lub sij hawm ntawm qhov kev kho yog ua tau. Lub sijhawm ntawm kev kho mob yog txiav txim los ntawm tus kws kho mob tshwj xeeb raws li cov ntaub ntawv ntawm tus nqi ntawm cov nqaij ua kom rov ua dua thiab nyob ntawm seb cov duab hauv chaw kuaj mob.
Kev tswj hwm Intravenous yog nqa tawm hauv daim ntawv ntawm infusions. Ib qho dej ntws tau muab tso rau 1 zaug ib hnub rau ntawm ib lub plab khoob. Cov tshuaj kua siab los yog daws yog diluted hauv 0.9% dej ntsev cov ntsev ua kua ntsev. Hauv cov tshuaj polyneuropathy mob hnyav, 24 ml ntawm Espa-Lipon yog diluted hauv 250 ml ntawm 0.9% sodium chloride tov. Lub khob dej yog muab tso rau 50 feeb.
Noj cov tshuaj rau ntshav qab zib
Cov neeg mob ntshav qab zib yuav tsum muaj ntshav qabzib tswj kev siv tus qauv ntawm Espa-Lipon.
Sab sij huam
Nrog rau kev siv cov tshuaj raws li cov lus qhia rau kev siv, kev pheej hmoo ntawm kev phiv yog txo qis. Muaj qee zaus, cov kev mob tshwm sim nram qab no tshwm sim:
- txo hauv plasma qab zib kom tsawg;
- kev ua xua tshwm sim ntawm daim tawv nqaij ua daim ntawv ntawm eczema lossis urticaria;
- nce hws;
- kev loj hlob ntawm anaphylactic kev poob siab thiab cov tsos ntawm hematomas.
Nrog tus nqi siab ntawm kev siv tshuaj, ua rau mob plab, ua kom tiav, mob taub hau, hnyav hauv cov tuam tsev, ua pa nyuaj yuav tshwm sim.
Feem ntau, cov kev mob tshwm sim yuav ploj mus ntawm lawv tus kheej.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tsis muaj qhov cuam tshuam ntawm kev ua haujlwm ntawm lub hauv nruab nrab thiab nruab nrab cov hlab ntsha txhaws. Txhawm rau pom tias kev txhim kho ntawm qhov tshwm sim tsis zoo (ua rau lub cev, kiv taub hau), kev saib xyuas yuav tsum tau saib xyuas thaum tsav tsheb cov khoom siv hauv lub tsheb thiab lub tsheb, vim hais tias cov haujlwm ntawd yuav tsum tau teb ceev ceev thiab kev xav.
Cov lus qhia tshwj xeeb
Nws yog ib qho tsim nyog yuav tsum tau qhia rau tus neeg mob txog qhov tshwm sim uas tshwm sim ntawm paresthesia - rhiab qhov cuam tshuam. Ib ntus pathological txheej txheem tawm tsam keeb kwm ntawm kev tsim dua tshiab ntawm cov hlab ntaws hauv kev kho mob polyneuropathy nrog alpha lipoic acid. Tus neeg mob yuav xav tias "goosebumps."
Cov neeg mob sai sai rau qhov tshwm sim ntawm anaphylactoid kev hloov pauv yuav tsum tau muab kuaj kev tsis haum ua ntej tso tshuaj. Los ntawm qhia txog 2 ml ntawm cov tshuaj hauv qab daim tawv nqaij, qhov thev taus ntawm cov tshuaj mus rau hauv lub cev tuaj yeem kuaj tau. Nyob rau hauv cov ntaub ntawv ntawm khaus, xeev siab thiab tsis xis nyob, kev siv tshuaj yuav tsum nres tam sim ntawd. Yog tias mob hlwb thiab mob anaphylactic tshwm sim, glucocorticosteroids yog qhov tsim nyog.
Thaum noj Espa-Lipon 600, kev pub mis niam tsis pom zoo.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj tau sau tseg thaum cev xeeb tub tsuas yog muaj mob hnyav nyob rau hauv uas muaj cov txiaj ntsig zoo ntawm alpha lipoic acid ntawm leej niam lub cev ntau dua qhov kev pheej hmoo ntawm intrauterine kev loj hlob tsis zoo hauv lub embryo. Xws li kev tshuaj ntsuam xyuas yog tsim nyog vim tias tsis muaj cov ntaub ntawv tshawb fawb txog lub peev xwm ntawm thioctic acid rau nkag mus rau hematoplacental barrier.
Hauv lub sijhawm ntawm kev siv tshuaj kho mob, kev pub mis niam tsis pom zoo.
Espa-Lipon Tshuaj rau 600 Cov Menyuam
Cov kev tshawb fawb soj ntsuam txog qhov tshwm sim ntawm cov tshuaj ntawm txoj kev loj hlob thiab kev loj hlob ntawm lub cev hauv cov menyuam yaus thiab thaum tiav hluas tseem tsis tau ua. Raws li kev ntsuas kev nyab xeeb, kev tswj hwm lossis kev tswj hwm ntawm alpha lipoic acid tsis pom zoo kom txog thaum muaj hnub nyoog 18 xyoo.
Siv rau lub sijhawm qub
Hauv cov neeg muaj hnub nyoog laus dua 50 xyoo, qhov tsis muaj tshuaj ntawm thioctic acid tsis tau pom thaum coj hauv daim ntawv ntsiav tshuaj, yog li cov neeg mob laus tsis tas yuav tsum kho cov koob tshuaj tshwj xeeb. Kev tswj cov leeg tsuas yog nqa tawm hauv qhov chaw mob thaum nyob ntawm kev saib xyuas ntawm tus kws kho mob.
Noj ntau dhau
Thaum noj 10-40 g ntawm cov tshuaj, hais tawm los ntshav tsis txaus siab tau pom, hypoglycemic coma tshwm sim, thiab cov kua qaub-lub hauv paus kev tshuav nyiaj hauv lub cev tau ntxhov. Kev qaug cawv hnyav pib. Tus neeg raug mob xav tau tsev kho mob sai.
Tus neeg raug tsim txom xav tau kev mus pw kho mob sai sai yog tias muaj kev noj ntau dhau ntawm Espa-Lipon 600.
Kev cuam tshuam nrog lwm yam tshuaj
Hauv chav kawm ntawm kev kawm ua ntej thiab tom qab kev tshawb fawb nrog kev siv ncaj qha ntawm Espa-Lipon nrog lwm yam tshuaj, kev sib cuam tshuam hauv qab no tau tshwm sim:
- Cov tshuaj qaug zog qhov ua tau zoo ntawm cisplatin.
- Nws yog ib qho tsim nyog los soj ntsuam cov ntshav plasma cov piam thaj nrog kev sib xyaw ntawm alpha-lipoic acid nrog insulin lossis lwm yam tshuaj hypoglycemic. Espa-Lipon muaj peev xwm txhim kho qhov rhiab ntawm peripheral cov ntaub so ntswg mus rau lub cev ntawm cov tshuaj beta hlwb ntawm cov txiav. Nyob ntawm cov txiaj ntsig tau txais, nws raug nquahu kom kho qhov ntau npaum li cas ntawm cov nyiaj tsim nyog kom ua tiav glycemic tswj.
- Thioctic acid muaj peev xwm los cuam tshuam nrog ionic hlau ntau dua thiab cov qauv tsim qauv ntawm saccharides, suav nrog levulose, los ua cov nyom. Yog li, txoj kev siv sib txig nrog cov tshuaj nrog cov khoom noj ntxiv, khoom noj siv mis nyuj (vim muaj cov calcium ions) los yog cov neeg sawv cev uas muaj cov hlau thiab ntsev ntsev yuav tsum raug txwv. Thaum kho cov tshuaj, nws raug nquahu kom soj ntsuam qhov sib nrug ntawm kev noj cov tshuaj Espa-Lipon thiab zaub mov rau 2-4 teev.
- Kws tshuaj tsis sib xyaw yog pom thaum diluting thioctic acid nyob rau hauv daim ntawv ntawm kev daws hauv 5% dextrose, Ringer txoj kev daws teeb meem.
Ib cov tshuaj tuaj yeem txhim kho cov tshuaj tiv thaiv ntawm glucocorticosteroids.
Cawv tau zoo
Thaum lub sij hawm kho cov tshuaj, kev haus dej haus cawv, tshuaj thiab khoom noj cov zaub mov uas muaj cawv ethyl yog raug txwv tsis pub muaj. Nrog rau txoj kev sib xyaw ntawm kev haus cawv thiab Espa-Lipon, lub zog tsis muaj zog ntawm cov kev kho kom zoo yog pom.
Thaum nkag mus ntawm Espa-Lipon 600, kev haus cawv muaj kev txwv tsis pub haus.
Ethyl cawv thiab nws cov khoom lag luam metabolic tuaj yeem ua rau muaj qhov tshwm sim ntawm kev rov ua dua polyneuropathy thaum noj Espa-Lipon ua ib qho kev tiv thaiv.
Analogs
Cov tshuaj hauv qab no ua nrog cov qauv tshuaj thiab hloov pauv nrog cov txheej txheem zoo ib yam ntawm kev ua ntawm Espa-Lipon:
- Oktolipen;
- Thioctacid BV;
- Berlition 600;
- Thiogamma;
- Thiolipone;
- Lipoic acid;
- Neuroleipone.
Hloov cov tshuaj tsis yog nrog los ntawm kev txo qis hauv cov tshuaj hauv lub lim tiam, vim Espa-Lipon tsis ua rau cov tsos mob tshem tawm.
Nyiaj so koobtsheej tej yam kev mob Espa Lipona 600 ntawm lub tsev muag tshuaj
Cov tshuaj yog muag hauv cov khw muag tshuaj los ntawm cov tshuaj noj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Nrog rau cov tshuaj tsis raug cai, qhov tshwm sim tsis zoo yuav tshwm sim, yog li muag dawb ntawm cov tshuaj tsis muaj kev qhia ncaj qha kev kho mob yog txwv.
Nqe rau espa lipon 600
Tus nqi nruab nrab ntawm cov tshuaj hauv cov ntawv pov thawj muag khoom txawv ntawm 656 txog 787 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov ntsiav tshuaj thiab cov tshuaj tov tau tso cai rau hauv qhov kub ntawm + 15 ... + 25 ° C. Rau kev saib xyuas cov ntaub ntawv cov tshuaj, cov mob uas tsis tshua muaj av noo thiab tsis muaj hnub ci yog qhov tsim nyog.
Hnub tas sij hawm
2 xyoos
Chaw tsim tshuaj paus Espa Lipona 600
Siegfried Hamelin GmbH, Lub Tebchaws Yelemees.
Cov tshuaj Espa-Lipon thiab cov tshuaj txhaj yuav tso rau hauv qhov kub ntawm + 15 ... + 25 ° C.
Kev txheeb xyuas ntawm Espa Lipone 600
Kev ua kom tiav cov kev mob ntshav qab zib lossis haus dej cawv ua kom ntshav qab zib, Espa-Lipon monotherapy tsis txaus, vim hais tias nyob hauv kev sib tham hauv Is Taws Nem cov neeg mob tau soj ntsuam ib nrab txoj kev kho zoo.
Cov kws kho mob
Olga Iskorostinskova, tus kws kho keeb (endocrinologist), Rostov-on-Don
Kuv xav tias Espa-Lipon yog cov tshuaj muaj txiaj ntsig zoo raws li thioctic acid. Kuv siv tshuaj yeeb tshuaj rau kev tswj hwm tshuaj, tom qab los ntawm kev hloov pauv mus rau kev noj tshuaj ntsiav tshuaj. Kuv saib lipotropic nyhuv hauv kev soj ntsuam xyaum. Cov tshuaj yuav pab txo kom qaug tshuaj ntawm lub cev. Qhov tsuas yog drawback yog tus nqi siab ntawm ob qho kev daws teeb meem thiab ntsiav tshuaj. Cov tshuaj yog tshuaj rau cov neeg mob ua tshuaj tiv thaiv kab mob rau cov ntshav qab zib polyneuropathies.
Elena Mayatnikova, kws kho mob hlwb, St. Petersburg
Espa-Lipon yog cov tshuaj kho tau zoo raws li kev ua haujlwm ntawm thioctic acid, ib qho kev lag luam hauv tsev. Kuv siv cov tshuaj rau kev kho mob polyneuropathy ntawm tus mob ntshav qab zib lossis dej cawv etiology, nrog rau kev puas tsuaj rau cov leeg hlwb ua haujlwm tiv thaiv cov keeb kwm yav dhau los ntawm cov syndromes. Cov neeg mob ntshav qab zib yuav tsum haus alpha-lipoic acid rau txoj kev noj tshuaj 2 zaug ib xyoos kom tiv thaiv qhov tshwm sim ntawm polyneuropathy. Hauv feem ntau cov neeg mob, cov tshuaj tau zoo txaus, thiab nws tsis tau pom muaj qhov tshwm sim tsis zoo hauv nws cov kev coj ua.
Cov neeg mob
Malvina Terentyeva, 23 xyoo, Vladivostok
Kuv txaus siab rau qhov tshwm sim tom qab kev kawm tag nrog kev kho mob nrog Espa-Lipon. Tus kws kho mob tau sau tshuaj rau noj vim yog muaj qhov tshwm sim ntawm kev hloov pauv-dystrophic hloov hauv lub txha caj qaum. Cov txheej txheem pathological tau tshwm sim nyob rau hauv daim ntawv ntawm osteochondrosis ntawm thawj degree. Lub cev tau tawm tsam zoo rau cov tshuaj, lub xeev kev noj qab haus huv zoo dua, thiab cov tshuaj tsis ua rau muaj kev phiv. Thaum tso ntshav los soj ntsuam, nws muab tawm hauv cov roj (cholesterol) tsawg dua: nws yog 7,5 mmol, nws tau dhau los ua 6. Cov plaub hau zoo tuaj.
Evgenia Knyazeva, 27 xyoo, Tomsk
Kuv siv cov tshuaj tsuas yog siv rau lub hom phiaj ntawm kev tiv thaiv. Hauv kev kho mob polyneuropathy, cov nyhuv ntawm cov tshuaj, ob qho tib si nrog kev tswj hwm qhov quav thiab nrog kev siv tshuaj, tsis tau sau tseg. Espa-Lipon tsis muaj peev xwm los txhim kho cov duab hauv chaw kuaj mob. Cov kws kho mob txhim kho cov nyhuv nrog lwm cov tshuaj, tom qab xaiv tsa Espa-Lipon ua kev tiv thaiv. Kuv ntseeg tias yam zoo tseem ceeb ntawm pheej yig tus nqi.
