Augmentin belongs rau cov tshuaj tua kabmob ntawm koob penicillin koob. Nws yog ib qho beta-lactamase inhibitor. Muaj ntau hom, nrog rau kev tswj hwm qhov ncauj. Lub hauv paus ntsiab lus ntawm cov tshuaj yog ua raws li kev muaj peev xwm txeem mus rau hauv cov xias ntawm cov kab mob pathogenic thiab muaj kev cuam tshuam tus nqi ntawm cov protein biosynthesis.
ATX
J01CR02.
Augmentin belongs rau cov tshuaj tua kabmob ntawm koob penicillin koob. Nws yog ib qho beta-lactamase inhibitor.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog muag nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, hmoov rau kev npaj ntawm syrup thiab lyophilized hmoov, los ntawm kev daws teeb meem rau kev txhaj tshuaj yog npaj. Hauv cov tshuaj muaj pes tsawg daim ntawv tshuaj, 2 lub ntsiab yog clavulanic acid thiab amoxicillin trihydrate. Qhov kev cia siab ntawm cov nquag tiv thaiv nyob ntawm daim ntawv tso tawm.
Augmentin 125 tau nthuav tawm hauv cov qauv foos. Cov tshuaj sib xyaw cov tshuaj tsuas muaj 500 lossis 875 mg ntawm amoxicillin trihydrate thiab 125 mg ntawm potassium clavulanate. Cov neeg tsim khoom lag luam muab cov khoom siv ntxiv uas ua rau kom cov neeg haus luam yeeb tshuaj:
- magnesium ntsev ntawm stearic acid;
- sodium carboxymethyl cellulose;
- polysorb;
- E460.
Txhua ntsiav tshuaj yog coated nrog zaj duab xis-plhaub, uas muaj:
- E171;
- hydroxypropyl methylcellulose;
- macrogol;
- kua roj silicone.
Cellular ntim ua los ntawm polyethylene thiab coated nrog ib txheej ntawm laminated ntawv ci tuav txog li 7-10 ntsiav tshuaj. Hauv cov thawv ntawv thawv - 1 blister nrog silica gel (1 sachet). Cov paub daws teeb tau ntim rau sab hauv, kos yog tam sim no nraub qaum pob. Cov hmoov nplej rau kev npaj dej haus thiab tshuaj ntxiv rau kev tso dej khov thiab tshuaj intramuscular yog muag rau hauv lub khob fwj. Cov phoov muaj qhov qab ntxiag thiab hnov ntxhiab vim tias muaj cov txiv tsw qab (txiv kab ntxwv).
Cov tshuaj yog muag nyob rau hauv daim ntawv ntawm hmoov rau kev npaj ntawm syrup.
Pharmacological kev txiav txim
Cov tshuaj tua kab los ntawm pawg penicillin muaj 2 ntu - clavulanic acid thiab amoxicillin. Qhov tom kawg yog cov tshuaj tiv thaiv kab mob ib nrab tawm tsam qee cov kab mob kev tiv thaiv kab mob. Clavulan yog ib qho kev xaiv b-lactamase inhibitor uas inactivates feem ntau cov kab mob enzymes.
Lub xub ntiag ntawm clavulan nthuav tawm lub spectrum ntawm kev ua ntawm cov tshuaj tua kabmob. Nws pab txhawm rau tiv thaiv kev rhuav tshem amoxicillin los ntawm cov kab mob enzymes. Cov tshuaj yog nquag tiv thaiv feem ntau cov kab mob me. Ib qho tsis tseem ceeb ntawm cov kab mob pathogenic muaj ntuj tsim lossis tau ua kom tsis haum rau cov tshuaj nquag ntawm cov tshuaj.
Amoxicillin txuam nrog b-lactamase inhibitor yog nquag tawm tsam gram-tsis zoo, gram-zoo, anaerobic thiab lwm yam kab mob.
Cov kab mob Gram-positive:
- Staphylococcus spp .;
- Bacillus anthracis;
- Staphylococcus saprophyticus;
- Enterococcus faecalis;
- Dab Tsi Staphylococcus aureus;
- Listeria monocytogenes;
- Streptococcus spp .;
- Nocardia asteroides;
- Tus kab mob Streptococcus agalactiae;
- Cov kab mob Streptococcus pyogenes.
Cov kab mob Gram-negative:
- Vibrio cholerae;
- Bordetella tus kab mob pertussis;
- Pasteurella multocida;
- Haemophilus mob npaws;
- Moraxella catarrhalis;
- Helicobacter pylori;
- Neisseria gonorrhoeae.
Anaerobic gram-cov kab mob zoo:
- Peptostreptococcus spp .;
- Clostridium spp .;
- Peptostreptococcus micros;
- Peptococcus niger;
- Peptostreptococcus magnus.
Anaerobic gram-cov kab mob tsis zoo:
- Prevotella spp .;
- Bacteroides fragilis;
- Porphyromonas spp .;
- Bacteroides spp .;
- Fusobacterium spp .;
- Capnocytophaga spp .;
- Fusobacterium nucleatum;
- Eikenella corrodens.
Lwm yam kab mob me me uas nkag siab rau cov tshuaj nquag muaj xws li Treponema pallidum, Borrelia burgdorferi thiab Leptospira icterohaemorrhagiae. Ntuj tsis kam lees yog pom nyob rau hauv Citrobacter freundii, Hafnia alvei, Yersinia enterocolitica, Chlamydia psittaci thiab Mycoplasma spp.
Kuj Klebsiella oxytoca, Klebsiella spp., Proteus vulgaris, Salmonella spp., Corynebacterium spp., Streptococcus pneumoniae thiab Shigella spp. suav hais tias nrhiav tau.
Tawm tsam keeb kwm yav dhau los ntawm kev siv lub sijhawm ntev ntawm ib qho kev tso tawm tshuaj, qhov kev pheej hmoo ntawm kev quav yeeb tshuaj nce ntxiv.
Cov Tshuaj Pharmacokinetics
Daim ntawv ntawm lub qhov ncauj yog xau tag nrho los ntawm lub plab zom mov. Tus nqi ntawm kev nqus ncaj qha nyob ntawm seb muaj khoom noj nyob hauv plab. Qhov siab tshaj plaws ntshav plasma yog mus txog tom qab 1-1.5 teev tom qab noj cov ntsiav tshuaj. Qhov kev faib tawm yog yam tsis sib thooj, hauv qhov ntau me me nws muaj nyob hauv cov nqaij mos, nqaij thiab pob txha, kua dej (peritoneal, synovial), adipose ntaub so ntswg thiab cov kua tsib.
Nws khi rau cov ntshav protein kom tsawg me me. Tsis tas. Nws ua tiav qhov placental barrier, muaj nyob hauv niam mis. Hauv cov txheej txheem ntawm kev hloov pauv roj ntsha, penicillic acid (ib qho tsis muaj zog ntawm cov metabolite) yog tsim nyob rau hauv daim siab. Cov tshuaj tawm hauv 3 txoj kev:
- ua ke nrog zis (ob lub raum);
- ua ke nrog quav (quav);
- ua ke nrog kev ua pa ntawm cov pa tawm (carbon dioxide).
Lub sijhawm tshem tawm yog 3-5 teev.
Kev ntsuas rau siv
Kev siv cov tshuaj tiv thaiv kab mob rau kev kho mob thiab kho kom zoo dua yog ua thaum kuaj pom tus neeg mob nrog qee cov kab mob uas cov neeg ua hauj lwm cuam tshuam nrog cov tshuaj tiv thaiv kab mob. Pathologies yog kis thiab kis hauv qhov. Cov no suav nrog:
- mob ua pa thiab mob ntev ntawm cov hlab ua pa (mob ntsws, mob ntsws, mob ntsws, mob ntsws, mob ntsws);
- kis kab mob ntawm cov pob txha thiab pob qij txha suav nrog osteomyelitis;
- kis kab mob ntawm daim tawv nqaij thiab cov nqaij mos (mob dermatitis, kis mob tom qab cov kab tom);
- kis mob ntawm pelvic plab hnyuv siab raum thiab mob tawm ntawm lub qhov zis (cystitis, urethritis).
Kev siv cov tshuaj tiv thaiv kab mob rau kev kho mob thiab kho hom phiaj yog ua tau rau hauv kev sib raug zoo ntawm cov kab mob me me uas nkag rau cephalosporins.
Puas yog nws muaj ntshav qab zib tau
Ntawm kev mob ntshav qab zib mellitus, kev siv tshuaj tiv thaiv kab mob tuaj yeem yog qhov mob rau kev noj qab haus huv. Ib nrab koob tshuaj thaum pib kho yog xav dua.
Cov Yuav Tsum Muaj
Yog tias lub raum ua rau lub ntsej muag tsis zoo, muaj (keeb kwm) ntawm lub ntsej muag daj tom qab ua ke ntawm amoxicillin thiab clavulan, kev tiv thaiv tsis txaus thiab / lossis kev tsis txaus siab rau qee yam ntawm ib cheeb tsam, kev siv cov tshuaj yog nruj me ntsis txwv. Cov me nyuam lub hnub nyoog kuj suav tias yog kev tsis kam lees tseeb: kev noj tshuaj rau cov menyuam hnub nyoog qis dua 12 xyoos thiab lub cev qhov hnyav dua li 35-40 kg yog txwv tsis pub.
Lub siab ua haujlwm pathologies yog qhov sib kis sib tiv thaiv, uas yuav tsum tau siv kom zoo.
Yuav noj li cas Augmentin 125
Cov tshuaj tua kab mob yuav tsum ua raws li tus txheej txheem qauv: tsis muaj qhov tawg, tsis muaj ploj hauv cov kua thiab haus dej ntau. Kev noj tshuaj yog txiav txim los ntawm tus kws kho mob mus kawm nyob ntawm tus yam ntxwv ntawm lub cev. Txhawm rau txo qhov kev pheej hmoo ntawm cov kev mob tshwm sim nrog kev siv tshuaj ntev, koj yuav tsum haus cov tshuaj ntawm ob peb feeb ua ntej noj mov.
Cov tshuaj tua kab mob yuav tsum ua raws li tus txheej txheem qauv: tsis muaj qhov tawg, tsis muaj ploj hauv cov kua thiab haus dej ntau.
Kev siv tshuaj rau txhua hnub rau cov laus thiab cov hluas yog tsis ntau tshaj 1500 mg, uas yog sib npaug rau 3 ntsiav tshuaj nrog qhov siab ntawm 500 mg / 125 mg lossis 6 ntsiav tshuaj ntawm 250 mg / 125 mg. Lub chav kawm ntawm kev pub nkag yog 10-14 hnub. Txoj kev kho kom zoo yog muab faib ua 3 koob tshuaj, lub caij nyoog nruab nrab uas yog 5-6 teev.
Sab sij huam
Tawm tsam keeb kwm yav dhau los ntawm kev siv lub sijhawm ntev thiab vim muaj qee tus yam ntxwv ntawm tus neeg mob lub cev, cov kev mob tshwm sim tuaj yeem tsim.
Kev kho mob txoj hnyuv
Feem ntau, muaj kev cuam tshuam ntawm lub plab zom mov yog qhia nyob rau hauv daim ntawv ntawm xeev siab, ntuav, tso quav (mob raws plab).
Los ntawm cov ntshav thiab lymphatic system
Los ntawm cov kab mob ntshav ncig, hemolytic anemia (thim rov qab), mob leukopenia, thrombocytosis, thrombocytopenia, agranulocytosis muaj cai.
Nruab nrab hauv lub paj hlwb
Hyperactivity, ntxhov siab, migraine, kiv taub hau, pw tsaug zog muaj kev cuam tshuam yog phiv los ntawm lub hauv nruab nrab lub paj hlwb.
Los ntawm cov kab mob zis
Hematuria, crystalluria yog cai.
Daim tawv nqaij thiab qog ua pa
Ua xua tau tshwm sim nyob rau hauv daim ntawv ntawm cov pob khaus ntawm daim tawv nqaij, khaus thiab kub.
Daim siab thiab nplooj siab
Cholestatic jaundice, tus mob muaj kab mob siab, ua rau lub siab hloov pauv siab tuaj vim yog cov mob tshwm sim los ntawm daim siab thiab nplooj siab.
Cov lus qhia tshwj xeeb
Thaum lub sij hawm sab laj, tus kws kho mob tshwj xeeb yuav tsum nug tus neeg mob kom huv thiab khaws cov pleev anamnesis. Qhov no yuav txheeb xyuas qhov ua tau contraindications thiab kos duab tsim nyog kev kho mob. Kev phiv tshuaj anaphylactic yuav ua tau rau neeg tuag taus. Yog tias muaj tshwm sim tshwm sim, cov tshuaj yuav tsum nres tam sim ntawd.
Cov kev ua kom sai ntawm cov tshuaj tiv thaiv kab mob tuaj yeem tshwm sim los ntawm kev siv lub sijhawm ntev siv tshuaj tua kab mob. Qhov kev tsis haum tshuaj twg yuav tsum tau tshem tawm ib cov tshuaj los ntawm txoj kev kho kom sai. Vim tias tsis muaj tshuaj lom ntau ntawm cov tshuaj penicillins, cov tshuaj tau txais txiaj ntsig zoo los ntawm cov neeg mob.
Cawv tau zoo
Cawv tsis haum nrog tshuaj tiv thaiv.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tsav tsheb yuav tsum xyuam xim.
Siv rau lub sijhawm qub
Rau cov neeg laus, yuav tsum ua zoo saib xyuas. Muaj peev xwm txo qis hauv kev kho mob rau ib hnub.
Koob tshuaj rau cov me nyuam
Cov ntsiav tshuaj tsis tau raug samfwm rau cov menyuam yaus hnub nyoog qis dua 12 xyoos. Ib qho kev ncua yog muaj rau lawv.
Siv thaum cev xeeb tub thiab lactation
Raug xaiv los kho mob. Kev txais tos zoo yog qhov xav tau los ntawm kev saib xyuas ntawm tus kws tshaj lij.
Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo
Qhov no yog ib tus txheeb ze contraindication. Kev saib xyuas zoo nrog kev tuaj yeem hloov kho ntau dua ntawm cov tshuaj ntau dua yog qhov zoo dua.
Cov neeg mob uas lub raum tsis ua hauj lwm zoo
Tshuaj tua kab mob hauv qhov no tsis tsim nyog.
Noj ntau dhau
Kev ua txhaum ntawm cov dej-electrolyte tshuav nyiaj, crystalluria thiab dyspepsia yog cov yam ntxwv ntawm tus cwj pwm tsis txaus. Nws yuav tsum siv plab thiab lo lus thov kom sai rau lub tsev kho mob, qhov chaw kws kho mob yuav xaiv cov kev kho mob tshwm sim.
Kev cuam tshuam nrog lwm yam tshuaj
Txoj kev pheej hmoo ntawm kev tsim cov kev tsis haum tshuaj nce ntxiv nrog kev siv tshuaj tua kab mob ua ke thiab Allopurinol tib lub sijhawm. Cov tshuaj ua ke nrog lwm cov tshuaj penicillin ua rau kom txo cov amoxicillin thiab clavulanic acid los ntawm lub cev. Cov tshuaj cuam tshuam rau lub ntuj hnyuv microflora thiab provokes kev loj hlob ntawm dysbiosis.
Cov qauv ntawm Augmentin 125
Cov tshuaj tua kab mob hloov pauv tau nthuav qhia hauv cov foos tshuaj. Lawv muaj nyob rau hauv nqe sib txawv. Cov qauv sib xyaw ua ke suav nrog txhua cov tshuaj ntsig txog rau penicillin pawg. Cov no suav nrog:
- Amosin. Hauv cov ntawv sau hauv cov tshuaj - amoxicillin trihydrate (500 mg). Lwm cov tshuaj yeeb dej caw tsis yog muab los ntawm cov tuam txhab tsim khoom. Tus nqi - los ntawm 35 rubles.
- Verklav. Cov yam ntxwv sib xyaw ua ke, muaj pes tsawg leeg yog tib yam li cov thawj. Concentration sib txawv (1000 mg / 200 mg). Nqe - los ntawm 70 rubles.
- Lub Ecoclave. Daim ntawv muab cov tshuaj muaj amoxicillin (250 mg, 500 mg thiab 875 mg) thiab clavulanic acid (62.5 mg thiab 125 mg). Tus nqi - los ntawm 150 rubles.
Txhua yam kab mob analogues muaj cov kab mob bacteriostatic ntawm lub cev thiab muab xa tawm hauv Latin.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Tso tawm los ntawm kev kho mob.
Nqi
Tus nqi ntawm ib daim ntawv ntsiav tshuaj hauv cov khw muag tshuaj yog los ntawm 130 rubles.
Cia rau cov neeg mob Augmentin 125
Cov ntsiav tshuaj tsis txaus los yog ntub dej yuav tsum tau muab pov tseg. Cov blisters nrog cov tshuaj tua kab mob tau khaws cia rau hauv lawv qhov chaw ntim deb ntawm menyuam yaus, hluav taws, noo noo thiab tshav ntuj.
Hnub tas sij hawm
Tsis pub ntau tshaj 36 lub hlis txij li hnub ntawm kev tsim khoom.
Kev txheeb xyuas rau Augmentin 125
Cov kws kho mob
Gennady Evstigneev, kws kho hniav, muaj kev kho mob phais, Khabarovsk
Cov tshuaj tau muaj pov thawj nws tus kheej hauv cov kab mob purulent-pathologies. Cov tshuaj yog ib qho kev pom ntawm qhov kev txiav txim, Kuv siv nws rau 5 xyoos tas los Nws muaj kev tiv thaiv zoo los ntawm cov neeg mob, cov kev tsis txaus siab ntawm cov kev mob tshwm sim tsis txaus ntseeg. Kuv tsis pom zoo kom muab tshuaj rau cov menyuam yaus vim tias qhov ua rau lub cev tsis muaj zog ntawm lub cev tsis taus.
Svetlana Zeytullaeva, otolaryngologist, Kostanay
Cov neeg mob ntshav qab zib feem ntau kuaj tau tus kab mob ua pa nyuaj. Hauv qhov no, kuv feem ntau sau ntawv rau tshuaj tua kab mob penicillin, nws ua tau zoo tshaj plaws rau laryngitis, tonsillitis, pharyngitis thiab sinusitis. Qee tus neeg mob ua xua uas tshem tawm nrog ib qho tshuaj pleev antihistamine.
Yog tias muaj tshwm sim tshwm sim, cov tshuaj yuav tsum nres tam sim ntawd.
Cov neeg mob
Valentina, 24 xyoo, Ekaterinburg
Ob peb lub hlis dhau los, kuaj pom ib qho kev txhab ntshav ntawm sab nqaij tawv. Tus kab mob yuav luag tsis muaj asymptomatic - txawm tias qhov ntsuas kub tsis yog qhov txawv me ntsis cawv. Kev ntxuav tsis pab, tom qab nws tshwm los ntawm pus. Tus kws kho mob sau tshuaj rau tshuaj tua kab mob. Tib lub sijhawm thaum noj cov ntsiav tshuaj, Kuv nquag ntxuav kuv lub qhov ntswg nrog kev tov. Tom qab 2 hnub, cov tsos mob tsis tshua pom tseeb, qhov mob yuav luag ploj. Lub sijhawm kho yog 10 hnub.
Roman, 41 xyoo, Novorossiysk
Tus mob tonsillitis raug mob tas li txij li menyuam yaus. Kuv tsis tuaj yeem tshem cov qog tawm vim qhov ua xua rau qhov tsis nco qab, yog li kuv sim "tsav" tus kab mob mus rau hauv kev kho kom sai li sai tau. Kuv tau txuag kuv tus kheej nrog tshuaj tua kab mob rau ntau xyoo tam sim no. Nws ua sai sai, mob thaum nqos dulls tom qab 4-5 teev. Phiv - dysbiosis thiab lwm yam teeb meem nrog cov hnyuv. Kis ntawm nws tus kheej hauv 2-3 hnub.
