Captopril Sandoz yog cov tshuaj siv tau zoo, ua yeeb yam sai rau kev kho mob ntshav siab. Nws yog qhia rau cov kab mob uas muaj kev pheej hmoo siab heev ntawm cov kab mob plawv.
Npe thoob ntiaj teb nonproprietary
Captopril
Atkh
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Captopril Sandoz yog cov tshuaj siv tau zoo, ua yeeb yam sai rau kev kho mob ntshav siab.
Tso cov ntaub ntawv thiab muaj pes tsawg leeg
Muaj nyob rau hauv cov ntsiav tshuaj, muaj cov cwj pwm hauv qab no:
- cov duab ib puag ncig lossis hauv daim ntawv uas muaj plaub-nplooj;
- xim dawb;
- nplaim yog homogeneous;
- Qhov kev pheej hmoo yuav raug rau ntawm ib lossis ob sab.
Nws yog tsim nrog cov ntsiab lus sib txawv ntawm lub ntsiab tivthaiv. Cov tso tawm, cov hnub so ntawm 6.25, 12.5, 100 mg, muaj cov duab puab puag ncig. Hauv daim foos ntawm plaub nplooj nplooj, cov ntaub ntawv muaj 50 thiab 25 mg ntawm cov tshuaj nquag muaj nyob.
Ntim hauv hlwv rau 10 ntau npaum. Lawv raug tso tawm rau hauv pob ntawv los ntawm cardboard. Cov kev qhia yog txuas.
Txhua qhov tso tawm muaj cov khoom xyaw uas nquag ua los ntawm captopril thiab cov khoom xyaw pabcuam. Cov tshuaj muaj pes tsawg leeg ntxiv:
- pob kws nplej siab;
- lactose monohydrate;
- microcrystalline cellulose;
- stearic acid.
Tsis muaj cov tebchaw tsim kev puas tsuaj, muab cov nyhuv kho kom tsim nyog.
Pharmacological kev txiav txim
Nws muaj cov cim suab hypotensive. Nws inhibits qhov sib txuas ntawm lub vasoconstrictor angiotensin II los ntawm hemodynamically tsis muaj zog angiotensin I. Nws txo qis kev zais ntawm aldosterone.
Txhawb nqa kev tsub zuj zuj ntawm bradykinin, uas cuam tshuam cov synthesis ntawm vasodilating prostaglandins.
Nrog lub caij nyoog siv nws muaj cov nyhuv cardioprotective:
- txo cov ua ntej- thiab tom qab;
- txhim kho cov ntshav txaus ntawm ischemic ib thaj chaw ntawm lub myocardium;
- nce coronary cia;
- kev ua haujlwm qeeb hauv qab ntawm kev txhim kho hypertrophy, dilatation ntawm sab laug ventricle;
- normalizes diastolic muaj nuj nqi.
Tsis ua rau mob reflex tachycardia. Txhawb lub cev hloov ntshav, txo cov platelet sib sau ua ke.
Tsim nyog cov koob tshuaj ntawm cov tshuaj rau lub plawv tsis ua rau tsis hloov ntshav siab. Pab txhawb rau kom muaj feeb ntau ntxiv, ua kom ib ce muaj zog.
Metabolically nruab nrab. Nws muaj cov poov tshuaj-sparing nyhuv. Cuam tshuam insulin rhiab heev.
Nws muaj cov nyhuv nephroprotective. Dilatation ntawm efferent raum ntsha pab txo qis intraglomerular siab. Nws inhibits intravascular proliferative tshua, normalizes tus qauv thiab kev khiav haujlwm ntawm epithelium.
Cov kev ua ntawm renin-angiotensin system qhia txoj kev txhim kho ntawm thawj qhov tshwm sim ntawm lub cev mus rau txoj kev noj tshuaj.
Chaw muag tshuaj
Cov tshuaj muaj cov kev lom neeg ncaj qha. Tsis muaj kev cuam tshuam cov ntaub so ntswg-angiotensin. Cov nyhuv hemodynamic yog txuam nrog vasodilation, tsis nyob ntawm theem ntawm renin hauv cov ntshav.
Captopril Sandoz yog tus kws kho mob ua ib feem ntawm txoj kev kho mob ntshav siab.
Raug rho tawm sai sai. Qhov pib ntawm kev nqis tes yog sau tseg tom qab 30 feeb. Lub bioavailability ntawm cov tshuaj yog siab. Kev tswj hwm ntawm ncauj tau muab cov nyhuv siab tshaj plaws tom qab 1 teev. Lub sijhawm tiv thaiv yog ntawm 4 txog 12 teev.
Nws yog cov roj hauv lub siab, ua rau lub cev tsis muaj zog. Txaus siab los ntawm ob lub raum. Ib feem ntawm cov tshuaj txuas nrog yog hloov tawm ntawm lub cev. Nws tuaj yeem sau ntau zog thaum tsis ua haujlwm ntawm lub raum. Ib nrab-lub neej nyob rau hauv cov xwm txheej zoo li no nce mus rau ib thiab ib nrab hnub.
Dab tsi pab
Nws yog feem ntau kho raws li ib feem ntawm txoj kev kho mob ntawm cov kab mob hauv qab no:
- ntshav siab
- mob ntshav qab zib nephropathy;
- mob ntsws raum;
- mob vwm rau lub plawv vwm.
Raws li kev kho mob monotherapy tau zoo nyob rau ntawm thawj theem ntawm txoj hlab ntaws, kev taug ua yam tsis muaj teeb meem.
Contraindications
Contraindicated nyob rau hauv cev xeeb tub, pub niam mis. Siv tsis tau rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Koj siv tsis tau cov tshuaj nrog:
- keeb kwm ntawm kev mob caj dab (angioedema) ntawm ib qho keeb kwm;
- ua kom lub ntsej muag tsis haum xeeb lossis lwm yam tshuaj ntawm pawg neeg no;
- ntshiab ntshav mob;
- thawj aldosteronism;
- lactose intolerance, lactase tsis txaus nyob rau hauv lub cev;
- ob leeg lub raum leeg txoj hlab ntsha hlwb los yog leeg ntshav ntawm ib raum.
Tus neeg ua txhaum cai siv tsis tau tom qab hloov raum.
Captopril tsis siv rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Nrog saib xyuas
Ceev faj yuav tsum tau siv rau cov kab mob hauv qab no:
- hypertrophic obstructive cardiomyopathy;
- ntshav qab zib mellitus;
- scleroderma, kab ke lupus erythematosus;
- mitral valve stenosis, aortic orifice;
- xeev kev hypovolemia;
- mob siab thiab lub raum tsis ua hauj lwm.
Thaum sau daim ntawv yuav tshuaj, nws yog ib qho tsim nyog yuav tsum tau coj mus rau hauv kev txiav txim siab siv cov ntsev uas tsis muaj zaub mov noj, kom muaj txiaj ntsig zoo.
Tsuas tshuaj
Kev muab tshuaj yog muab tib neeg. Nrog lub raum pathology, nws yog ib qhov tsim nyog los ua kom pom tseeb ntawm creatinine tshem tawm cov ntsuas. Hauv cov xwm txheej zoo li no, kev siv tshuaj tsawg kawg yog siv, ncua sijhawm ntev dua ntawm cov koob tshuaj.
Nrog myocardial infarction
Daim ntawv tshuaj thaum ntxov ntawm cov tshuaj tau qhia rau myocardial infarction nyob rau hauv cov ntaub ntawv ntawm lub chaw ruaj khov ntawm tus neeg mob. Pib kev kho mob nrog qhov tsawg kawg yog 6.25 mg rau ib hnub. Kev muaj txiaj ntsig ntawm kev txais neeg kawm tau maj mam nce ntxiv, ua tiav ntawm cov txiaj ntsig zoo.
Ntawm lub siab
Nws yog ib qho tsim nyog yuav tsum pib kho nrog qhov siv tshuaj tsawg kawg, tswj kev kam rau ua siab ntev ntawm thawj koob. Txib 12,5 mg ob zaug ib hnub. Kev noj tshuaj kom tsawg zuj zus yog pom zoo kom ua tiav qib theem. Cov neeg mob hauv cov pab pawg hnub nyoog laus tau sau tseg qhov tsawg kawg ntawm cov tshuaj.
Hauv kev mob plawv tsis ua haujlwm, ua ntej pib kev kho mob, tshuaj diuretics raug muab tso tseg lossis lawv cov koob tshuaj txo qis.
Nyob rau hauv mob plawv tsis ua hauj lwm
Ua ntej pib kev kho mob, diuretics raug muab tso tseg lossis lawv cov koob tshuaj txo qis. Pib nrog kev tso cai tsawg kawg nkaus rau ib zaug, uas nce ntau zuj zus. Qhov tsis muaj qhov tshwm sim tsis zoo tso cai rau koj siv cov tshuaj kom ntev. Qhov koob tshuaj txhua hnub tau muab faib ua 2 koob.
Nrog ntshav qab zib nephropathy
Thawj qhov tshuaj yog 75-100 mg ntawm cov tshuaj ib hnub. Kev nquag siv yog raug kho los ntawm tus kws kho mob uas tuaj koom. Yuav kom ua tiav qhov txiaj ntsig zoo tshaj plaws, kev teem caij raws li ib feem ntawm kev sib koom ua ke tau qhia.
Yuav ua li cas noj captopril sandoz
Nws raug nquahu kom noj cov tshuaj 1 teev ua ntej noj mov. Cov koob tshuaj yog xaiv tau tus kheej nyob ntawm tus kab mob.
Nyob rau hauv tus nplaig lossis dej haus
Cov txheej txheem ntawm kev noj tshuaj yog txiav txim siab los ntawm qhov mob hnyav ntawm tus mob. Nrog kev npaj kho mob, cov tshuaj yuav tsum nqos tag nrho, ntxuav nrog dej kom txaus.
Thaum muaj teeb meem tshwm sim, kev tso cai rau kev kho mob raug tso cai.
Kev ua ntawm cov tshuaj tshwm sim sai sai, tom qab 30 feeb. Qhov txiaj ntsig zoo tshaj plaws nrog kev tswj hwm ntawm qhov ncauj yog pom thaum thawj teev.
Nws ua haujlwm ntev npaum li cas
Kev ua ntawm cov tshuaj tshwm sim sai sai, tom qab 30 feeb. Qhov txiaj ntsig zoo tshaj plaws nrog kev tswj hwm ntawm qhov ncauj yog pom thaum thawj teev.
Kuv haus tau pes tsawg
Nws yog kev hais daws luv luv. Ib koob tshuaj yog noj ob zaug ib hnub. Thaum kev txiav txim siab ntawm tus kws kho mob, kev tso cai nkag 3 zaug. Kev kho mob siab ntsws tau ua tiav los ntawm kev siv kab ke thiab ntev ntev.
Phiv los ntawm captopril sandoz
Qhov tsis xav kom ntau yam tshwm sim yog tsawg, tab sis tuaj yeem ua rau muaj kev mob tshwm sim heev. Cov kev mob tshwm sim feem ntau tsis tas yuav muaj kev cuam tshuam, ploj nrog tsis txiav txuas ntawm cov tshuaj.
Lub plab zom mov
Kev noj tshuaj yuav tuaj yeem nrog kev hloov pauv ntawm qhov qab, tsis qab los noj mov. Tsis tshua muaj qhov mob plab, mob plab tsis haum. Qee lub sij hawm muaj qhov nce ntxiv ntawm qhov kev txiav txim ntawm bilirubin thiab hepatic transaminases.
Hematopoietic plab hnyuv siab raum
Kev siv lub sijhawm ntev ntawm cov tshuaj yog nrog los ntawm kev loj hlob ntawm neutropenia, thrombocytopenia, thiab txo qis ntawm hemoglobin qib. Cov kev tsis zoo li no tshwm sim tsawg, dhau ntawm lawv tus kheej.
Kev siv ntev ntev ntawm cov tshuaj yog nrog los txo cov ntshav hauv hemoglobin. Cov kev tsis zoo li no tshwm sim tsawg, dhau ntawm lawv tus kheej.
Cov leeg hauv nruab nrab
Kiv taub hau, mob taub hau ntau tshwm sim hauv thawj hnub ntawm kev tuaj kawm. Tsis tas yuav kho tshwj xeeb. Cov nyhuv ntawm cov tshuaj tuaj yeem nrog lub siab zoo li qaug zog, tsis quav ntsej, kev txhim kho ntawm paresthesia, asthenia.
Los ntawm cov kab mob zis
Cov tshuaj muaj peev xwm ua rau txo qis ntawm glomerular pom. Cov xwm txheej zoo li no yuav tsum tau txo koob tshuaj lossis tshem tawm tshuaj, ua tib zoo saib xyuas kev noj qab haus huv.
Los ntawm kev ua pa
Cov hnoos qhuav tshwm sim ntau zaus. Tej zaum qhov kev loj hlob ntawm rhinitis, qhov kev xav zoo li tsis muaj huab cua. Cov kev mob tshwm sim hnyav tshaj plaws suav nrog bronchospasm. Nws yog tsawg.
Ntawm ib sab ntawm daim tawv nqaij
Kev noj tshuaj ntau zaus yog nrog tawv nqaij ua kom tawm pob, ua kom tawm pob. Lub sijhawm ntev ntawm kev siv cov tshuaj ua rau kev loj hlob ntawm lymphadenopathy. Tsawg dua yog pom dermatitis thiab urticaria.
Ua xua
Muaj kev pheej hmoo ntawm kev tsim Quincke edema. Cov tsos mob ntawm tus mob angioedema hauv cov leeg ntshav ua rau hawb thaiv kev ua pa. Cov tshuaj raug muab tso tseg, epinephrine muab tshuaj tam sim ntawd, thiab cov cua nkag tau ywj pheej.
Thaum noj captopril, koj yuav tsum zam qhov tsav tsheb.
Cuam tshuam rau kev muaj peev xwm los tswj cov tshuab
Zam kev tsav tsheb. Tsis txhob koom nrog kev ua haujlwm cuam tshuam nrog kev nce siab thiab qhov tseeb ntawm kev tua.
Cov lus qhia tshwj xeeb
Ua txoj kev kho mob yuav tsum tau saib xyuas tsis tu ncua ntawm cov hemodynamic thiab lub raum kev ua haujlwm.
Nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus lej muaj peev xwm tsim muaj hypovolemia thaum siv ua ke nrog diuretics. Ib qho xwm txheej zoo li no cuam tshuam nrog kev mob vascular, kev tuag, txawm tias tuag.
Kom zam dhau txoj kev loj hlob ntawm cov teeb meem pab:
- kev hloov kho koob;
- tso tseg ua ntej ntawm diuretics;
- normalization ntawm hemodynamic tsis.
Cov hlab ntsha raum leeg yuav tsum them ib feem ntawm ib koob tshuaj, tshuaj xyuas lub xeev ntawm cov leeg tso zis.
Proteinuria thaum siv koob tshuaj ntau dua yog txo los yog ploj nws tus kheej.
Nws yog ib qho tsim nyog kom tsis txhob muaj kev sib txig sib luag ntawm cov tshuaj muaj cov poov tshuaj.
Ceev faj tshuaj rau pathology ntawm cov nqaij mos sib txuas, coj los kho kev tiv thaiv kab mob. Nws yog ib qho tseem ceeb uas tswj cov ntsiab lus ntawm cov qe ntshav dawb thiab lwm cov qe ntshav.
Yuav tsum muaj kev soj ntsuam cov ntshav qabzib kom tsawg.
Kev txhim kho ntawm cholestatic jaundice, kev nce ntxiv ntawm lub titer ntawm hepatic transaminases yuav tsum tau tshem tawm cov tshuaj tam sim ntawd.
Kev kho nrog cov tshuaj tau nres ib hnub ua ntej pib kev npaj phais mob.
Thaum cev xeeb tub, captopril tuaj yeem siv tsis tau.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj muaj teratogenic siv. Thaum cev xeeb tub tsis tuaj yeem siv.
Kev rho tawm nrog niam cov kua mis txwv kev siv cov tshuaj thaum lactation.
Cawv siv tau
Kev cuam tshuam nrog cov dej cawv ua kom muaj txiaj ntsig zoo rau cov tshuaj tiv thaiv, uas ua rau kev ua txhaum ntawm cov ntshav mus rau cov plab hnyuv siab raum thiab cov ntaub so ntswg. Zoo xws li cov xwm txheej hem qhov kev loj hlob ntawm cov mob vascular mob.
Kev siv dej cawv ua rau muaj txiaj ntsig kom sai ntawm kev tshem cov poov tshuaj tawm hauv lub cev, tshem tawm cov txiaj ntsig zoo ntawm cov tshuaj ntawm lub plawv mob.
Cawv txhawm rau txhim kho lub plab zom ntawm cov hlab ntsha, muaj cov nyhuv tsis zoo. Tej zaum qhov kev txhim kho orthostatic vau.
Noj tshuaj ntau ntawm captopril sandoz
Kev noj tshuaj ntau dua ntawm cov tshuaj ua rau muaj kev mob hauv lub cev, ua rau muaj kev phom sij txog lub neej. Qhov kev txo qis hauv lub zog ua haujlwm ntawm lub plawv yog nrog los ntawm txoj haujlwm tsis txaus ntawm sab laug ventricle, poob rau hauv hemodynamics, thiab kev txhim kho ntawm lub xeev collaptoid. Cov tsos mob ntawm lub raum tsis ua haujlwm tshwm sim.
Cov xwm txheej no xav tau kev kho mob kub ceev. Yaug lub plab. Muab sorbents. Rov ntxiv cov roj ntshav, ua kev kho mob cov tsos mob.
Kev siv ntau yam nrog rau diuretics tuaj yeem ua rau kev loj hlob ntawm hypotension, qhov txo qis hauv cov ntsiab lus ntawm cov poov tshuaj hauv cov ntshav ntshav, thiab hypovolemia.
Cuam tshuam nrog lwm yam tshuaj
Kev siv ntau yam nrog rau diuretics tuaj yeem ua rau kev loj hlob ntawm hypotension, qhov txo qis hauv cov ntsiab lus ntawm cov poov tshuaj hauv cov ntshav ntshav, thiab hypovolemia.
Kev siv cov poov tshuaj npaj, cov zaub mov ntxiv yog cuam tshuam nrog kev txhim kho hyperkalemia thiab kev ua haujlwm ntawm lub raum.
Kev mob siab rau ntshav yog tshwm sim los ntawm cov tshuaj uas siv rau cov tshuaj loog.
Nws yog tsis yooj yim sua kom sib txuas kev txais tos nrog Aliskiren thiab lwm yam ACE inhibitors.
Daim ntawv thov nrog allopurinol ua rau pom kev ntawm neutropenia, nce qhov kev pheej hmoo ntawm kev tsis haum tshuaj loj.
Cov nyhuv hypotensive ntawm cov tshuaj yog txhim kho los ntawm beta-blockers, calcium antagonists, nitrates, tshuaj tsaug zog, tshuaj tiv thaiv kab mob.
Cov tshuaj tsub kom cov concentration ntawm digoxin hauv cov ntshav nce ntxiv.
Nws muaj kev pheej hmoo ntawm hypoglycemia thaum sib cuam tshuam nrog cov kab mob hypoglycemic.
Kev ua kom qis qis dua ntawm kev tshem tawm cov roj ntsha lithium, nce ntxiv ntawm lawv cov ntshav tawm.
Thaum sib cuam tshuam nrog kub npaj, Cov nyhuv hypotensive yog kho dua.
Indomethacin, ibuprofen txo cov nyhuv ntawm cov tshuaj. Zoo sib xws tau sau tseg nrog kev siv tshuaj estrogen, tshuaj tiv thaiv qhov ncauj, corticosteroids.
Siv nrog antacids thiab zaub mov txo lub bioavailability ntawm cov tshuaj los ntawm 40%.
Analogues
Analogues ntawm cov tshuaj, zoo sib xws nyob rau hauv muaj pes tsawg leeg thiab mechanism ntawm kev ua:
- Kapoten;
- Captopril-Akos;
- Alkadil;
- Epsiron
- Captopril Hexal.
Txawv hauv lub tebchaws, npe, nqe. Xaiv ib qho analogue tom qab sab laj nrog kws kho mob.
Cov nqe lus so ntawm lub tsev muag tshuaj
Tso tawm los ntawm kev kho mob.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Txwv tsis pub muag dawb.
Nqi rau captopril sandoz
Tus nqi nws txawv ntawm 83 txog 135 rubles rau ib pob.
Cia tej yam kev mob ntawm cov tshuaj
Khaws rau hauv qhov chaw tiv thaiv los ntawm lub teeb thiab noo noo. Khaws tsis ncav cuag ntawm cov menyuam yaus. Cia qhov kub thiab txias tsis tshaj + 25˚С.
Hnub tas sij hawm
2 xyoos txij li hnub muab cov teebmeem no, uas tau hais rau ntawm pob ntawv.
Tsim kom muaj
"Salutas Pharma GmbH" (Lub Tebchaws Yelemees).
Sandoz, Switzerland.
Lub chaw tsim khoom ntawm captopril sandoz yog lub tuam txhab Sandoz, Switzerland.
Kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog captopril sandoz
Eugene, kws kho plawv, 46 xyoo, Krasnodar
Cov tshuaj yeeb yam yog luv-yeeb yam, zoo tiv thaiv. Tus nqi yog tsim nyog. Kuv pom zoo tsuas yog thaum muaj xwm txheej ceev. Rau lwm lub hom phiaj, nws zoo dua yog siv cov khoom lag luam ntev ntev.
Natalia, 46 xyoo, Novosibirsk
Thawj zaug kuv tau siv tshuaj los txwv kev kub siab. Nws ua sai sai, tsis muaj kev phiv tshuaj. Tam sim no kuv coj raws li kws kho mob hais tseg.
Lika, 53 xyoo, Rybinsk
Kuv tau kev mob siab los ntawm kev mob ntshav siab tau ntau xyoo. Kuv muab ntau yam txhais tau tias. Cov tshuaj no zoo tshaj plaws. Kuv lees txais los ntawm kev saib xyuas ntawm kws kho mob. Zoo nrog kub siab crises, sai sai normalizes qhov mob. Cov kev xav tsis zoo tsis ua.
