Ciprolet 500 yog ib qho zoo tshaj plaws ntawm fluoroquinolone tshuaj uas muaj ntau yam kev siv. Nws tuaj yeem siv rau kev kho mob thiab tiv thaiv ntawm ntau yam mob thiab kis mob, tab sis ua ntej pib kev kho mob, nws raug nquahu kom kuaj xyuas qhov muaj feem ua rau muaj kab mob me me rau cov tshuaj tua kab mob no.
ATX
Cov tshuaj yog rau cov pab pawg tshuaj ntawm quinolones thiab muaj tus lej ATX ntawm J01MA02.
Ciprolet 500 yog ib qho zoo tshaj plaws ntawm fluoroquinolone tshuaj uas muaj ntau yam kev siv.
Tso cov ntawv thiab cov nyob ua ke
Cyprolet tau ua hauv cov ntawv hauv qab no:
- enteric coated ntsiav tshuaj;
- Txoj kev lis ntshav daws;
- qhov muag tee.
Raws li cov tshuaj muaj sia, ciprofloxacin siv nyob rau hauv lawv.
Kev noj tshuaj ntawm 500 mg tsuas muaj ib ntsiav tshuaj hloov ntawm cov tshuaj. Cov ntsiav tshuaj yog dawb, puag ncig, convex ntawm ob sab. Cov nquag ua ke nyob rau hauv daim ntawv ntawm hydrochloride yog tam sim no nyob rau hauv tus nqi ntawm 0.25 lossis 0.5 g. Lub hauv paus tseem muaj:
- croscarmellose sodium;
- microcellulose;
- magnesium stearate;
- silicon dioxide;
- chaw muag tshuaj;
- pob kws nplej siab.
Zaj duab xis txheej yog tsim los ntawm kev sib xyaw ntawm hypromellose, dimethicone, titanium dioxide, macrogol, talc, sorbic acid thiab polysorbate.
10 ntsiav tshuaj faib rau hauv blisters. Cov thawv ntim khoom. 1 blister phaj thiab cov lus qhia rau kev siv raug muab tso rau hauv nws.
Ciprolet yog siv los ua tshuaj tua kab mob.
Pharmacological kev txiav txim
Ciprolet yog siv los ua tshuaj tua kab mob. Nws cov tshuaj tiv thaiv yog ciprofloxacin, ib qho tshuaj tua kab mob ntawm cov fluoroquinolone koob. Tus txheej txheem ntawm kev ua ntawm qhov kev sib txuas no yog qhov inhibition of topoisomerases ntawm hom II thiab IV, lub luag haujlwm rau supercoiling ntawm cov kab mob DNA.
Cov tshuaj tua kab mob ua rau pom cov kab mob bactericidal. Nyob rau hauv nws cov cawv, DNA kev faib tawm yog thaiv, kev loj hlob thiab rov ua dua ntawm cov kab mob me me tau nres, cov qog thiab lub cell ua puas tsuaj, uas ua rau cov kab mob tuag. Qhov no tso cai rau koj los rhuav tshem cov kab mob gram-negative pathogens uas yog nyob rau hauv kev ua ub ua no thiab ntawm kev so. Cov tshuaj tseem ua rau cov kab mob gram-zoo pathogens, tab sis tsuas yog thaum lawv nyob rau theem ntawm kev ua me nyuam.
Ciprofloxacin tsis qhia tiv thaiv kev sib chwv nrog penicillins, aminoglycosides, tetracyclines, cephalosporins thiab lwm yam tshuaj tua kab mob uas tsis thaiv DNA gyrase. Yog li, nws ua haujlwm zoo qhov twg cov tshuaj tsis ua haujlwm no. Nws ua haujlwm tawm tsam ntau pathogens, nrog rau:
- Moraxella catarrhalis;
- Salmonella
- Ntxaug Yaj
- neiseries;
- Klebsiella;
- Cuam Tshuam
- daim ntawv teev npe;
- pob tsuas;
- kev nkag mus thiab cytobacteria;
- vibrios;
- plab hnyuv, hemophilic, Pseudomonas aeruginosa;
- mob chlamydia
- ib co staph thiab streptococci.
Fecal enterococcus thiab Mycobacterium avium xav tau kev siv cov tshuaj hauv qhov siab. Nws yog qhov tsis muaj txiaj ntsig tawm ntawm kev mob ntsws, kab mob treponema, ureaplasma, mycoplasma, bacteroids, flavobacteria, Pseudomonas maltophilia, Clostridium difficile, Nocardia asteroides, feem ntau anaerobes, tsis ua txhaum lub ntuj hnyuv thiab qhov paum ntawm microflora.
Kev tawm tsam tuaj yeem sib txawv raws lub sijhawm thiab nyob ntawm geolocation. Txais kev txhim kho maj mam pib.
Cov Tshuaj Pharmacokinetics
Cov tshuaj sib xyaw ua ke yog nqus tau los ntawm txoj hnyuv me, kom txog lub siab nyob hauv ntshav 1-2 teev tom qab noj cov ntsiav tshuaj. Khoom noj khoom haus txo tus nqi ntawm kev nqus, tab sis tsis cuam tshuam rau ntawm lub xyoob ntoo, uas tuaj yeem ncav cuag 80%. Cov tshuaj tua kab mob nkag mus rau ntau yam kua dej (peritoneal, ophthalmic, kua tsib, tso zis, qaub ncaug, lymph, synovia, hnoos qeev, cov ntshav txhaws), tau zoo faib rau cov ntaub so ntswg:
- mob siab
- gall zais zis;
- poj niam muaj me nyuam;
- txoj hnyuv;
- peritoneum;
- lub prostate;
- ntsws thiab pleura;
- raum thiab mob txeeb zig;
- articular pob qij txha;
- musculoskeletal qauv thiab tawv nqaij.
Nyob rau tib lub sijhawm, cov ntaub so ntswg ntau yog ob peb zaug (txog 12) siab dua ntshav ntshav.
Cov tshuaj kis tau rau niam mis, hla lub qe ntshav thiab ntshav ntshav-thaiv cov nyom. Cov ntsiab lus ntawm ciprofloxacin nyob rau hauv lub cerebrospinal kua hauv qhov tsis muaj txheej txheem ntawm qhov nruab nrab yog 8% ntawm nws cov ntshav hauv cov ntshav, thiab nrog cov kab mob ua paug tuaj yeem ncav cuag 37%. Kev sib txuas lus nrog cov ntshav protein - 20-40%.
Kev ua ib feem ntawm cov tshuaj Ciprolet 500 yog tsim los ntawm daim siab, cov khoom noj ua rau pom qee yam haujlwm.
Kev ua ib feem ntawm cov tshuaj yog nqa tawm los ntawm daim siab, metabolites qhia qee yam haujlwm. Txog li 70% ntawm cov koob tshuaj tau coj tshwm nyob hauv nws daim ntawv qub. Lub luag haujlwm tseem ceeb ntawm kev nthuav tawm yog ntog rau ntawm ob lub raum. Qhov kev tshem tawm ib nrab-lub neej yog 3-6 teev. Hauv kev mob raum tsis ua haujlwm, qhov ntsuas no tuaj yeem ua rau ob npaug, tab sis cov tshuaj tsis txhim kho, vim tias nws txoj kev nthuav tawm los ntawm txoj hnyuv txuas ntxiv mus. Nrog lub raum ua haujlwm, cov quav ua kom khiav tawm 1% ntawm thawj zaug.
Dab tsi pab
Cov tshuaj hauv cov nqe lus nug yog npaj los tawm tsam pathogenic microflora, uas yog rhiab rau ciprofloxacin. Cov ntsiab lus rau kev teem caij Cyprolet:
- Kab mob ua pa: mob ua pa nyuaj, mob ntsws, ntsws, bronchiectasis, kab mob ntsws, yog tias nws tsis yog los ntawm mob ntsws, ua mob rau cystic fibrosis, legionellosis, empyema thiab mob ntsws.
- Cov kab mob Otolaryngological: sinusitis, otitis media, mastoiditis, pharyngitis, agranulocytic tonsillitis.
- Cov mob urogenital: pyelonephritis, cystitis, tubulointerstitial nephritis, oophoritis, endometritis, salpingitis, orchitis, epididymitis, prostatitis, balanoposthitis, gonorrhea.
- Peritonitis thiab lwm yam kev mob siab hauv plab. Ntawm no, cov tshuaj tua kab mob yog siv ua ib feem ntawm txoj kev kho mob nyuaj.
- Tus kab mob cholecystitis, suav nrog rau qhov mob tsis meej, cholangitis, empyema ntawm lub zais zis.
- Digestive system kab mob, suav nrog shigellosis, typhoid fever, kab mob raws plab.
- Kev kis mob ntawm kev sib xyaw thiab cov kab mob subcutaneous: abscesses, phlegmon, furunculosis, qhov txhab, mob txhab, hlawv nrog cov cim ntawm kev kis mob theem ob.
- Kab mob musculoskeletal: myositis, bursitis, tendosynovnovitis, osteomyelitis, mob caj dab.
- Sepsis, bacteremia, mob ntsws anthrax, mob hauv cov neeg mob uas lub cev tsis muaj zog tiv thaiv (nrog neutropenia lossis nrog cov tshuaj tiv thaiv kab mob).
- Kev tiv thaiv kev kis mob, suav nrog Neisseria meningitidis thiab Bacillus anthracis.
Tsiprolet 500 tuaj yeem siv tsis tau thaum coj tus menyuam.
Cov Yuav Tsum Muaj
Cov tshuaj yuav tsum tsis txhob siv yog tias muaj pes tsawg leeg tsis sib haum lossis muaj keeb kwm ntawm qhov mob siab rau tshuaj fluoroquinolone. Lwm qhov tsis zoo contraindications suav nrog:
- pseudomembranous enterocolitis;
- noj tizanidine vim tias qhov kev pheej hmoo ntawm mob ntshav siab ceev;
- thaum yau thiab thaum tiav hluas (nws tau tso cai siv Ciprolet rau cov menyuam yaus txij 5 xyoo kom thiaj li ua rau muaj kev cuam tshuam ntawm kev ua haujlwm ntawm Pseudomonas aeruginosa thaum muaj mob cystic, nrog rau kev tshem tawm thiab tiv thaiv kev sib kis nrog Bacillus anthracis);
- coj menyuam;
- kev pub mis.
Nrog saib xyuas
Kev tswj hwm tshwj xeeb yog xav tau nyob rau cov neeg laus laus, cov neeg mob uas muaj cov kab mob hepatic-raum tsis ua hauj lwm, mob tsis muaj ntshav txaus, lub cev tsis muaj zog.
Yuav ua li cas coj Ziprolet 500
Cov tshuaj yog siv tshwj rau cov lus qhia los ntawm kws kho mob. Ntsiav tshuaj tuaj yeem noj tau txawm tias yuav noj mov. Yog tias koj haus dej ntawm lub plab khoob, ces lawv yuav ua sai dua. Lawv raug muab nqos thiab tag nrho coj mus ntxuav nrog dej. Kev siv ib txhij siv cov tshuaj yog contraindicated nyob rau hauv nrog cov kua txiv hmab txiv ntoo enriched nrog cov zaub mov, thiab nrog rau cov khoom noj siv mis (nrog rau cov kua mis nyeem hauv tsiav tshuaj raws li probiotic).
Cov tshuaj Ciprolet tsuas yog siv tshwj xeeb qhia los ntawm kws kho mob.
Koob tshuaj tau txiav txim siab ib tus zuj zus nyob ntawm qhov ntsuas, qhov tsis haum ntawm cov kab mob, qhov mob loj thiab thaj chaw ntawm qhov chaw txhab txhab. Cov neeg laus noj 500 mg ntsiav tshuaj ib hnub ob zaug. Yog tias tsim nyog, ib koob tshuaj ntxiv tau nce. Kev noj tshuaj txhua hnub yuav tsum tsis pub tshaj 1.5 g.Yog xav tau, cov tshuaj yog muab nrog nrog nrog hloov mus rau kev tswj hwm hauv qhov ncauj. Intramuscular txhaj tsis haum.
Cov koob tshuaj thaum pib thiab txij nkawm raug pom zoo rau cov neeg mob uas lub raum tsis ua haujlwm. Nrog creatinine tshem tawm hauv qab 30 ml / min, lub sijhawm nruab nrab ntawm cov koob tshuaj ntxiv nce mus rau 24 teev. Rau cov menyuam yaus thiab tub ntxhais hluas, cov tshuaj tua kab mob yog tsim nyog thaum tsim nyog kiag li, vim tias nws tuaj yeem ua rau mob arthropathy. Koob tshuaj yog xam raws qhov hnyav ntawm tus me nyuam.
Qee qhov mob sib kis thiab mob txhab (kev kis mob ntawm pob txha pob txha mos, plab hnyuv plab, thiab lub plab mog) yuav tsum siv lwm cov tshuaj tua kab mob sib kis. Qhov nruab nrab ntawm lub sijhawm kho yog 1-2 lub lis piam. Qee zaum kev kho mob ncab ntev mus rau ntau lub hlis.
Nws puas tuaj yeem noj cov tshuaj rau ntshav qab zib
Tsis muaj kev sib deev rau txoj kev siv Ciprolet los ntawm cov ntshav qab zib. Lub peev xwm ntawm cov tshuaj uas ua rau hloov pauv nyob rau hauv cov piam thaj hauv ib qho kev taw qhia lossis lwm qhov yuav tsum tau xav txog.
Thaum noj Ciprolet, kev txwv tsis pub hematopoietic kev ua haujlwm thiab kev hloov pauv hauv cov cell muaj pes tsawg leeg cov ntshav ua tau.
Sab sij huam
Cov tshuaj tua kab mob tau pom zoo zoo, tab sis qee qhov xwm txheej nws tuaj yeem ua rau muaj ntau qhov kev tsis zoo.
Kev kho mob txoj hnyuv
Cov neeg mob yws yws ntawm kev xeev siab, ntuav, kev loj hlob ntawm raws plab, mob plab, flatulence. Tsis tshua muaj, candidiasis ntawm lub qhov ncauj mucosa, laryngeal edema, mob caj dab txhaws, ua haujlwm ntawm lub siab (tsis xws li daim siab tsis ua haujlwm), mob siab, mob nqaij necrosis, cholestasis, nce kev ua haujlwm ntawm daim siab enzymes, pseudomembranous enterocolitis.
Hematopoietic plab hnyuv siab raum
Kev txwv tsis pub hematopoietic kev ua haujlwm thiab kev hloov pauv hauv cov cell muaj pes tsawg leeg ntawm cov ntshav, suav nrog leukocytosis thiab pancytopenia, muaj peev xwm ua tau.
Nruab nrab hauv lub paj hlwb
Kiv taub hau, mob taub hau, mob nkees heev, asthenia, ntxhov siab heev, insomnia, kev nyuaj siab, kev puas siab puas ntsws, muaj teeb meem nrog kev sib koom tes ntawm kev txav, kev tshee, kev pom qhov tsis txaus ntseeg, paresthesia, neuropathy, saj thiab tsw hnov ntxhias, lub suab nrov hauv lub pob ntseg, thim rov qab hnov, tsis hnov lus thiab lwm yam kev pom txawv txav.
Los ntawm cov kab mob zis
Kev noj tshuaj tiv thaiv kab mob tuaj yeem ua rau cuam tshuam hauv kev ua haujlwm ntawm lub raum, qhov tshwm sim ntawm cov ntshav ntawm cov zis, kev txhim kho ntawm crystalluria, thiab kev nce ntawm creatinine concentration.
Thaum noj Cyprolet 500, kiv taub hau, mob taub hau, thiab qaug zog yuav tshwm sim.
Los ntawm cov hlab plawv system
Muaj peev xwm ua rau tachycardia, hypotension, kub dhau los, lub ntsej muag liab, ntev ntawm QT luv ntawm daim cardiogram, pirouette arrhythmia, vasculitis.
Kev ua xua
Feem ntau, cov tawv nqaij tshwm sim: ua pob, o, hyperemia, khaus, urticaria. Qee zaum cov pob xoo liab tshwm sim. Photosensitization, malignant erythema, ua tsis tau cov lus sib xyaw, bronchospasm, anaphylactic ceeb, kub taub hau, mob hauv cov leeg thiab pob qij txha yog qhov ua tau.
Cov lus qhia tshwj xeeb
Hauv cov txhab mob hnyav, kab mob streptococcal, kab mob tshwm sim los ntawm tus kab mob anaerobic pathogens, kev kho mob nrog Tsiprolet yuav tsum tau ntxiv nrog lwm cov tshuaj tua kab mob.
Zawv plab yog tsim los ntawm kev noj tshuaj tiv thaiv kab mob uas tsis tuaj yeem tshem tawm nrog kev pab ntawm cov tshuaj uas txwv lub cev ua haujlwm lub cev.
Ciprofloxacin tuaj yeem ua rau mob leeg nqaij, mob ntsig txog qaug dab peg, thiab kev tsim kho superinfection.
Cawv tau zoo
Thaum noj cov tshuaj tua kab mob, cov dej cawv thiab cov tshuaj muaj dej cawv yuav tsum tsis txhob haus.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Kev phiv los ntawm cov leeg thiab cov plab hnyuv siab raum yog qhov ua tau, yog li ntawd, thaum tsav tsheb thiab tswj cov cuab yeej muaj peev xwm txaus ntshai, yuav tsum tau saib xyuas.
Siv thaum cev xeeb tub thiab lactation
Cov poj niam cev xeeb tub thiab cov niam uas tsis tau tu tus menyuam hauv lub mis, noj cov tshuaj yog contraindicated.
Cyprolet rau 500 tus menyuam
Lub hnub nyoog txwv yog 18 xyoo. Cov tshuaj yuav siv tau rau lub sijhawm menyuam yaus tsuas yog siv rau kev kho mob thiab tiv thaiv ntawm tus mob ntsws pulmonary anthrax lossis los tawm tsam Pseudomonas aeruginosa hauv cov neeg mob cystic fibrosis. Tab sis nyob rau hauv cov rooj plaub no, nws yog qhov yooj yim dua rau kev siv tshuaj ntau npaum li 250 mg, ntau dua li 500 mg.
Noj ntau dhau
Cov tsos mob ntawm kev overdose:
- mob taub hau
- xob vwj;
- cramps
- tshee hnyo
- mob hauv plab;
- ua kom pom tseeb;
- lub raum mob rau cov hlab ntsws;
- kua siv lead ua los;
- cov ntshav hauv cov zis.
Nws yog ib qho tsim nyog kom khoob lub plab thiab nqa tawm cov tsos mob kev kho mob. Nws yog ib qho tseem ceeb los saib xyuas kev ua haujlwm ntawm lub raum thiab ua raws li kev txhim kho kev haus dej haus cawv. Kev lim ntshav yog qhov ua tsis zoo.
Cov poj niam cev xeeb tub thiab cov niam uas tsis noj mis tsis pub mis ntawm tus menyuam noj, noj ciprolet yog sib kis.
Kev cuam tshuam nrog lwm yam tshuaj
Ciprolet nce cov ntsiab lus ntawm Theophylline hauv cov ntshav plasma, ua rau txo qis kev tiv thaiv kab mob hauv lub qhov ncauj, xanthines thiab NSAIDs (tshwj tsis yog Aspirin), txhim kho cov nephrotoxicity ntawm Cyclosporin thiab ua haujlwm ntawm Warfarin. Kev npaj ntawm cov hlau nplaum, hlau, txhuas thiab zinc qeeb qeeb kev nqus ntawm ciprofloxacin, yog li koj xav tau siv nrog qhov luv ntawm 4 teev.
Cov tshuaj nyob rau hauv nqe lus nug yog sib xws nrog lwm cov tshuaj tua kab mob:
- Metronidazole;
- Vancomycin;
- cephalosporins;
- penicillins;
- aminoglycosides;
- tetracyclines.
Nws txoj kev tshem tawm qis qis nyob rau hauv lub xub ntiag ntawm Probenecid, thiab nyob rau hauv kev sib xyaw nrog NSAIDs, qhov kev pheej hmoo ntawm kev hnov mob tshwm sim ntau dua.
Cov qauv ntawm Tsiprolet 500
Tus qauv tshuaj tiv thaiv cov tshuaj:
- Ciprofloxacin.
- Cyprocinal.
- Afenoksim.
- Tsiprosan.
- Tsiproksin.
- Medociprine.
- Ciprinol.
- Quintor li al.
Cov tshuaj sib xyaw nrog lwm cov tshuaj tua kab mob hauv qhov muaj pes tsawg leeg, piv txwv li, Ciprolet A nrog tinidazole, tuaj yeem kho tshuaj.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Tso tawm los ntawm kev kho mob.
Nqi
Tus nqi ntawm 500 mg ntsiav tshuaj yog los ntawm 54 rubles. rau ib pob (10 pcs.).
Cia rau cov neeg mob ntawm Tsiprolet 500
Cov tshuaj no tau muab tso cia hauv qhov hluav taws xob hauv qhov kub txog + 25 ° C hauv qhov chaw tsis ncav cuag rau menyuam yaus.
Hnub tas sij hawm
3 xyoos
Cov tshuaj no tau muab tso cia hauv qhov hluav taws xob hauv qhov kub txog + 25 ° C hauv qhov chaw tsis ncav cuag rau menyuam yaus.
Kev txheeb xyuas txog Tsiprolet 500
Cov tshuaj tau txais ntau qhov kev tshuaj xyuas zoo los ntawm cov kws kho mob thiab cov neeg mob.
Cov kws kho mob
Kartsin N.S., Urologist, Tver
Cov tshuaj tua kab mob fluoroquinolone no tshwj xeeb tshaj yog ua rau mob hnyav rau ntawm txoj hnyuv genitourinary mob. Nws raug nquahu kom pre-sow.
Turimova O. N., kws kho mob, Krasnodar
Cov tshuaj muaj qhov pom dav ntawm qhov kev txiav txim. Nws ua haujlwm nrawm. Cov kev mob tshwm sim muaj tsawg.
Cov neeg mob
Lyudmila, 41 xyoo, lub nroog Kerch
Kuv coj tshuaj kho tus mob angina. Thawj hnub nws nyuaj nws yuav nqos. Tab sis qhov tshwm sim txaus siab: muaj caj pas zoo thiab tsis muaj kev phiv.
Anatoly, 37 xyoo, Ryazan
Kuv haus cov tshuaj no nrog exacerbation ntawm mob ntsws ntev rau 5 hnub, txawm hais tias cov tsos mob ploj lawm rau 3-4 hnub. Thaum kws kho mob sau ib qho tshuaj ntxiv lawm, vim tias qhov zawv plab zawv pib muaj ntau ntxiv. Yog li kuv tsuas yuav kho nrog Cyprolet. Nws lub cev pom ntau yam zoo dua.
