Protafan NM Penfill yog ib tus neeg sawv cev nrog kev kho mob uas nws ua yog tsom rau kev kho mob ntshav qab zib mellitus. Cov tshuaj, thaum siv kom raug, tso cai rau koj ua raws li qhov yuav tsum tau muaj cov piam thaj hauv cov ntshav, tsis ua rau muaj mob rau tus neeg mob.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Neeg insulin.
ATX
A.10.A.C - insulins thiab lawv cov analogues nrog qhov nruab nrab ntawm kev txiav txim.
Tso cov ntawv thiab cov nyob ua ke
Kev ncua rau kev coj ua subcutaneous ntawm 100 IU ml muaj nyob rau hauv daim ntawv ntawm: lub raj mis (10 ml), cartridge (3 ml).
Cov tshuaj muaj pes tsawg leeg 1 ml ntawm cov tshuaj muaj:
- Cov khoom xyaw nquag: insulin-isophan 100 IU (3.5 mg).
- Ntu cov khoom siv: glycerol (16 mg), zinc chloride (33 μg), phenol (0.65 mg), sodium hydrogen phosphate dihydrate (2.4 mg), protamine sulfate (0.35 mg), sodium hydroxide (0.4 mg) ), metacresol (1.5 mg), dej rau kev txhaj tshuaj (1 ml).
Kev ncua rau kev coj ua subcutaneous ntawm 100 IU ml muaj nyob rau hauv daim ntawv ntawm: lub raj mis (10 ml), cartridge (3 ml).
Pharmacological kev txiav txim
Hais txog cov kab mob hypoglycemic uas muaj lub sijhawm nruab nrab ntawm kev txiav txim siab ntev. Nws yog tsim los ntawm recombinant DNA technology siv Saccharomyces cerevisiae. Nws cuam tshuam nrog membrane receptors, sib sau ua ib qho insulin-receptor complex uas txhim kho cov synthesis ntawm enzymes koom rau hauv lub neej (hexokinases, glycogen synthetases).
Cov tshuaj yog txhawb kev thauj mus los ntawm cov protein los ntawm lub cev ntawm lub cev. Raws li qhov tshwm sim, cov piam thaj tau txhim kho, lipo- thiab glycogenesis yog kho, thiab cov piam thaj ntau ntxiv los ntawm daim siab yog txo qis. Tsis tas li ntawd, cov khoom cua protein ua kom rov ua haujlwm.
Cov Tshuaj Pharmacokinetics
Qhov ua tau zoo ntawm cov tshuaj thiab qhov nrawm ntawm nws qhov kev txiav txim siab yog txiav txim siab los ntawm qhov ntau npaum li cas, qhov chaw txhaj tshuaj, hom kev txhaj tshuaj (subcutaneous, intramuscular), cov tshuaj insulin nyob rau hauv cov tshuaj. Cov ntsiab lus siab tshaj plaws ntawm cov khoom hauv cov ntshav tau mus txog tom qab 3-16 teev tom qab txhaj tshuaj subcutaneously.
Kev ntsuas rau siv
Mob ntshav qab zib
Protafan NM Penfill yog ib tus neeg sawv cev nrog kev kho mob uas nws ua yog tsom rau kev kho mob ntshav qab zib mellitus.
Cov Yuav Tsum Muaj
Nrog hypersensitivity rau tib neeg cov insulin los yog cov tshuaj uas tsim cov tshuaj, hypoglycemia yog txwv tsis pub.
Nrog saib xyuas
Ceev faj tau siv thaum tsis saib xyuas cov zaub mov ib txwm noj lossis kev siv lub cev ua haujlwm ntau dhau hypoglycemia yuav tshwm sim. Ceev faj kuj tseem ceeb thaum hloov los ntawm ib hom tshuaj insulin mus rau lwm tus.
Yuav ua li cas noj Protafan NM Penfill?
Ua intramuscular lossis subcutaneous txhaj tshuaj. Cov koob tshuaj yog xaiv noj rau hauv tus account qhov tshwj xeeb thiab yam ntxwv ntawm tus kab mob. Kev tso cai ntawm cov tshuaj insulin txawv ntawm 0.3-1 IU / kg / hnub.
Siv cov tshuaj insulin siv cov koob txhaj tshuaj. Cov neeg muaj insulin tsis kam ua qhov xav tau ntawm insulin ntau ntxiv (thaum lub sijhawm kev sib deev, muaj lub cev nyhav dhau los), yog li lawv tau raug muab ntau tshaj plaws.
Txhawm rau txo qis kev pheej hmoo ntawm lipodystrophy, nws yog ib qho tsim nyog yuav tau hloov chaw xa mus ntawm cov tshuaj. Kev ncua kev kawm, raws li cov lus qhia, raug txwv nruj kom tsis txhob nkag rau hauv qhov ncauj.
Nrog ntshav qab zib
Protafan yog siv rau txhua yam ntshav qab zib. Txoj kev kho kom zoo pib nrog hom ntshav qab zib 1. Hom tshuaj 2 yog raug tshuaj yog tias tsis muaj tshwm sim los ntawm sulfonylurea derivatives, thaum lub sijhawm cev xeeb tub, thaum lub sijhawm thiab tom qab phais mob, nrog cov kab mob sib xyaw ua rau muaj qhov tsis zoo ntawm kev mob ntshav qab zib.
Qhov tshwm sim ntawm Protafan NI Penfill
Cov xwm txheej tsis zoo tshwm sim hauv cov neeg mob thaum lub sijhawm kho cov tshuaj yog tshwm sim los ntawm kev quav thiab cuam tshuam nrog pharmacological kev txiav txim ntawm cov tshuaj. Ntawm cov kev mob tshwm sim tsis xwm yeem, hypoglycemia tau sau tseg. Tshwm sim yog qhov txiaj ntsig ntawm qhov tsis ua raws li qhov tau muab tshuaj rau ntawm cov tshuaj insulin.
Hauv cov ntshav qog ntshav hnyav, poob ntawm kev nco qab, ua kom qaug dab peg, ua tsis tau haujlwm ntawm lub hlwb, thiab qee zaum kev tuag, muaj peev xwm ua tau. Hauv qee kis, muaj kev ua txhaum ntawm cov metabolism hauv cov metabolism.
Ntawm ib feem ntawm kev tiv thaiv kab mob hauv nruab nrog cev muaj peev xwm ua tau: tawm pob, urticaria, tawm hws, khaus, ua tsis taus pa, lub plawv dhia ceev ceev, txo cov ntshav siab, poob siab.
Ntawm ib feem ntawm lub cev tiv thaiv kab mob, qhov tshwm sim tsis zoo yog ua tau: tawm pob, urticaria, khaus.
Lub leeg poob siab tseem nyob rau qhov txaus ntshai. Muaj qee zaus, mob puas hlwb neipia.
Cov lus qhia tshwj xeeb
Kev xaiv tshuaj tsis raug cai los sis kev txiav tawm ntawm kev kho mob ua rau hyperglycemia. Cov tsos mob thawj zaug pib tshwm li ntawm ob peb teev lossis hnub. Yog tias tsis tau txais kev pabcuam raws sijhawm, kev pheej hmoo ntawm kev loj hlob ketoacidosis, uas cuam tshuam loj rau ib tus neeg lub neej, nce.
Nrog concomitant pathologies uas tau nthuav qhia los ntawm kub taub hau lossis kis tus kab mob, qhov xav tau ntawm insulin hauv cov neeg mob nce ntxiv. Yog tias tsim nyog, hloov cov tshuaj nws tuaj yeem hloov kho thaum lub sijhawm txhaj thawj lossis nrog rau kev kho mob ntxiv.
Siv rau lub sijhawm qub
Cov neeg mob uas muaj hnub nyoog txog 65 xyoos tsis muaj kev txwv rau kev noj cov tshuaj. Tau mus txog lub hnub nyoog no, cov neeg mob yuav tsum nyob hauv kev saib xyuas ntawm tus kws kho mob thiab txiav txim siab txog lwm yam xwm txheej.
Tshuaj Tiv Thaiv Protafan NM Penfill rau menyuam yaus
Yuav siv tau rau cov menyuam yaus hnub nyoog qis dua 18 xyoo. Qhov ntau npaum li cas cov tshuaj tau tsim ib lub zuj zus raws kev nug. Feem ntau siv nyob rau hauv daim ntawv diluted.
Siv thaum cev xeeb tub thiab lactation
Siv thaum cev xeeb tub, raws li tsis txhob tso cov txiaj ntsig. Yog hais tias cov ntshav qab zib tsis tau kho nyob rau hauv lub sijhawm xeeb tub, qhov kev pheej hmoo mus rau tus menyuam hauv plab.
Teeb meem hypoglycemia tshwm sim nrog kev xaiv tsis raug xaiv ntawm txoj kev kho mob, uas ua rau muaj kev pheej hmoo ntawm cov tsis xws luag hauv tus menyuam thiab ua rau nws nrog kev tuag intrauterine. Hauv thawj peb lub hlis, xav tau cov tshuaj insulin tsawg dua, thiab hauv 2 thiab 3 nws nce. Tom qab yug menyuam tas, qhov xav tau cov tshuaj insulin yuav zoo li qub.
Cov tshuaj tsis txaus ntshai thaum pub niam mis. Nyob rau qee qhov xwm txheej, yuav tau kho kom haum rau kev txhaj tshuaj lossis noj zaub mov noj.
Noj ntau tshaj ntawm Protafan NI Penfill
Cov koob tshuaj uas ua rau noj ntau dhau tsis muaj qhia. Rau txhua tus neeg mob, coj mus rau hauv tus account qhov tshwj xeeb ntawm chav kawm ntawm tus kab mob, muaj koob tshuaj siab, uas ua rau pom qhov tshwm sim ntawm hyperglycemia. Nrog rau lub xeev tsis muaj ntshav qab zib, tus neeg mob tuaj yeem tiv thaiv nws ntawm nws tus kheej los ntawm kev noj zaub mov qab zib thiab zaub mov uas muaj cov carbohydrates ntau. Nws tsis ua mob rau tas li muaj cov khoom qab zib rau tes, ncuav qab zib, kua txiv hmab txiv ntoo lossis tsuas yog ib qho qab zib.
Hauv cov ntawv hnyav (tsis nco qab lawm), cov kua dej qabzib (40%) yog txhaj rau txoj leeg ntshav, 0.5-1 mg ntawm glucagon nyob hauv qab daim tawv nqaij lossis cov leeg. Thaum ib tug neeg coj mus rau kev nco qab, txhawm rau kom zam kev pheej hmoo ntawm rov ua dua, lawv muab cov zaub mov muaj cov zaub mov ntau rau cov noj.
Kev cuam tshuam nrog lwm yam tshuaj
Kev siv tshuaj hypoglycemic nce ntxiv rau cov nyhuv ntawm insulin. Tus neeg saib xyuas cov tshuaj monoamine oxidase, carbonic anhydrase thiab angiotensin hloov enzyme, Bromocriptine, Pyridoxine, Fenfluramine, Theophylline, tshuaj muaj ethanol, Cyclophosphamide ntxiv cov tshuaj insulin zoo.
Kev siv cov tshuaj tiv thaiv hauv qhov ncauj, cov thyroid hormones, Heparin, Phenytoin, Clonidine, Diazoxide, morphine thiab nicotine, glucocorticosteroids ua rau cov tshuaj tsis muaj zog. Reserpine thiab salicylates, Lanreotide thiab Octreotide muaj peev xwm txhim kho thiab txo qhov cuam tshuam ntawm cov khoom xyaw nquag.
Beta-blockers nkaum thawj cov tsos mob ntawm kev ua qog ntshav thiab ua rau nws cuam tshuam nrog kev tshem tawm ntxiv.
Cawv tau zoo
Cawv ua kom zoo dua qub thiab ua kom ntev ntev li cov nyhuv ntawm cov tshuaj.
Analogs
Hloov tshuaj uas muaj cov nyhuv zoo sib xws: Protamine-insulin thaum muaj xwm ceev, Gensulin N, Humulin NPH, Insuman Bazag GT.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Los ntawm tshuaj.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Tsis yog.
Nqi
Tus nqi ntawm ib lub raj mis 10 ml yog 400-500 rubles, tus cartridge yog 800-900 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj yuav tsum muab cia rau hauv qhov chaw txias thiab tsaus ntawm qhov kub ntawm + 2 ... + 8 ° C (tuaj yeem tso rau hauv tub yees, tab sis tsis yog lub tub yees). Nws tsis yog raug rau khov. Lub cartridge yuav tsum tau ceev cia rau hauv nws lub ntim los tiv thaiv nws los ntawm tshav ntuj.
Lub taub qhib qhib tau muab cia rau 30 ° C rau tsis pub dhau 7 hnub. Tsis txhob muab cia rau hauv tub yees. Txwv tsis pub siv cov menyuam yaus nkag.
Hnub tas sij hawm
2.5 xyoo. Tom qab nws raug nquahu kom pov tseg.
Chaw tsim tshuaj paus
NOVO NORDISK, A / S, Denmark
Xyuas
Tus kws kho mob uas koom nrog pom zoo hloov mus rau kev txhaj tshuaj tiv thaiv Protafan NM Penfill. Tus mob zoo li qub tsis pom tshwm sim thoob plaws lub sijhawm cev xeeb tub thiab tom qab ntawd. "
Konstantin, hnub nyoog 47 xyoo, Voronezh: "Kuv muaj ntshav qab zib tau 10 xyoo. Tag nrho lub sijhawm kuv nrhiav tsis tau txoj cai tshuaj rau kev tswj cov piam thaj hauv kuv cov ntshav. Tsuas yog rau lub hlis dhau los kuv tau yuav Protafan NM Penfill txhaj tshuaj thiab kuv zoo siab nrog qhov tshwm sim. cov teeb meem thiab cov teeb meem uas pom dhau los tsis ua rau lawv tus kheej xav tau ntxiv lawm. Tus nqi pheej yig. "
Valeria, 25 xyoo, St. Petersburg: "Kuv tau mob ntshav qab zib txij li menyuam yaus. Kuv tau sim ntau dua 7 yam tshuaj, thiab tsis muaj ib qho twg kiag li txaus siab. Cov tshuaj kawg uas kuv yuav rau cov lus qhia ntawm kuv tus kws kho mob tau raug ncua ntawm Protafan NM Penfill. Txog thaum kawg, kuv tsis ntseeg nws Kuv tsis cia siab tias qhov xwm txheej yuav hloov. Tab sis kuv pom tias qhov pib ntawm lub qog ntshav tsis muaj kev txhawj xeeb lawm, kuv lub cev noj qab haus huv tsis zoo. Kuv tau yuav hauv lub raj mis. Cov tshuaj yooj yim siv thiab pheej yig. "
