Txhawm rau cov theem ntawm cov piam thaj hauv cov ntshav, cov tshuaj sib txawv yog siv, uas suav nrog Merifatin. Kev siv tshuaj hypoglycemic muaj contraindications thiab phiv, yog li ua ntej pib kev kho mob, koj yuav tsum mus ntsib tus kws kho mob tshwj xeeb thiab kawm cov lus qhia.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Metformin.
Txhawm rau cov theem ntawm cov piam thaj hauv cov ntshav, cov tshuaj sib txawv yog siv, uas suav nrog Merifatin.
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A10BA02.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob hauv daim ntawv ntawm 500 ntsiav tshuaj, 850 mg thiab 1000 mg coated zaj duab xis. Lawv muab tso rau hauv 10 daim. rau hauv lub hlwv. Ib daim npav cardboard tej zaum yuav muaj 1, 2, 3, 4, 5, 6, 8, 9 lossis 10 hlwv. Cov ntsiav tshuaj muaj peev xwm muab tso rau hauv lub thawv polymer ntawm 15 pcs., 30 pcs., 60 pcs., 100 pcs. lossis 120 pcs. Tus nquag ua hauj lwm yog metformin hydrochloride. Ntu cov khoom siv yog povidone, hypromellose thiab sodium stearyl fumarate. Cov dej-soluble film zaj duab xis muaj polyethylene glycol, titanium dioxide, hypromellose thiab polysorbate 80.
Pharmacological kev txiav txim
Cov tshuaj yog qhov ncauj qhov ncauj hypoglycemic txog rau biguanides. Kev nquag ua hauj lwm pab txhawb kev tiv thaiv gluconeogenesis, kev tsim cov roj dawb dawb thiab ua kom tawv nqaij oxidation. Ua tsaug rau kev tswj hwm tshuaj, cov cuab yeej siv sab nrauv muaj kev cuam tshuam ntau ntxiv rau cov tshuaj insulin thiab cov kua nplaum siv los ntawm cov cell tau txhim kho. Tus nqi ntawm cov insulin hauv cov ntshav tsis hloov pauv, tab sis qhov sib piv ntawm cov insulin khi thiab cov insulin pub dawb tsawg thiab qhov sib piv ntawm insulin thiab proinsulin nce.
Thaum pom cov glycogen synthetase, metformin kev txhim kho glycogen synthesis. Nws qhov kev ua yog tsom rau nce kev thauj mus los ntawm txhua hom kev thauj cov kua nplaum hauv lub qog. Cov tshuaj ua rau kom qis dua qhov nqus ntawm cov piam thaj hauv lub plab zom mov, txo cov ntshav LDL, triglycerides thiab VLDL, thiab tseem txhim kho cov fibrinolytic yam ntxwv ntawm cov ntshav, inhibiting cov nqaij mos plasminogen activator inhibitor. Thaum lub sij hawm kho cov tshuaj metformine, tus neeg mob qhov hnyav tseem nyob ruaj khov los yog maj mam txo qis kom ib txwm muaj qhov muaj kev rog.
Nrog rau kev siv cov khoom noj thooj txhij, kev nqus ntawm cov tshuaj maj mam poob qis.
Cov Tshuaj Pharmacokinetics
Tom qab noj cov ntsiav tshuaj, nws txoj kev nqus qeeb thiab ua tsis tiav hauv qhov kev zom zaub mov tshwm sim. Qhov siab tshaj plaws ntawm ib yam khoom hauv cov ntshav ntshav yog pom tom qab 2.5 teev. Nrog rau kev siv cov khoom noj thooj txhij, kev nqus ntawm cov tshuaj maj mam poob qis. Cov tshuaj nquag nkag rau hauv tag nrho cov ntaub so ntswg ntawm tib neeg lub cev, kev xyaum ua yam tsis muaj kev khi rau cov ntshav protein.
Nws accumulates nyob rau hauv lub raum, mob siab thiab salivary qog. Kev tshem tawm ib nrab-lub neej ntawm metformin yuav siv sijhawm ntev li 2 mus rau 6 teev. Cov tshuaj siv tawm hauv cov zis hauv qhov tsis hloov pauv. Kev cog qoob loo ntawm cov nquag muaj peev xwm ua tau teeb meem nrog lub raum.
Kev ntsuas rau siv
Cov tshuaj yog tawm rau cov neeg mob uas mob ntshav qab zib hom 2, tshwj xeeb tshaj yog cov nyhav dhau heev lawm, thaum kev noj zaub mov zoo thiab kev ua si lub cev tsis ua hauj lwm. Rau kev kho mob ntawm cov neeg laus cov neeg mob, nws tuaj yeem siv los ua kev kho mob los yog sib xyaw nrog insulin los yog lwm yam kab mob hypoglycemic.
Rau cov menyuam yaus tom qab 10 xyoo, cov tshuaj yuav siv ib leeg lossis ua ke nrog cov tshuaj insulin. Ntxiv rau, cov ntsiav tshuaj yog siv los tiv thaiv tus kabmob thaum muaj mob ntshav qab zib thiab lwm yam kev pheej hmoo rau kev loj hlob ntawm tus mob ntshav qab zib hom 2, thaum muaj kev tswj xyuas ntshav qabzib txaus tsis tuaj yeem ua tiav nrog kev hloov pauv hauv lub neej.
Cov tshuaj yog tawm rau cov neeg mob uas mob ntshav qab zib hom 2, tshwj xeeb tshaj yog cov nyhav dhau heev lawm, thaum kev noj zaub mov zoo thiab kev ua si lub cev tsis ua hauj lwm.
Cov Yuav Tsum Muaj
Nws yog qhov tsim nyog yuav tsum tsis kam lees kho yog tias:
- lub cev tsis haum rau Cheebtsam;
- mob ketoacidosis;
- cov uas ua rau muaj ntshav qab zib ua ntej lossis coma;
- raum lossis mob siab ua haujlwm;
- lub cev qhuav dej;
- cov kab mob kis hnyav;
- cov kab mob hauv cov mob hnyav los yog mob ntev, ua rau cov nqaij mos hypoxia.
Nrog saib xyuas
Lawv ua tib zoo siv tshuaj rau kev phais mob ntau thiab kev raug mob thaum tsim nyog yuav tsum tau siv tshuaj insulin, cev xeeb tub, ntev cawv lossis qaug dej qaug cawv, ua raws li cov zaub mov uas tsis muaj calorie, lactic acidosis, ntxiv rau ua ntej lossis tom qab xoo xaim radioisotope lossis xoo hluav taws xob, thaum lub sijhawm muaj tshuaj tiv thaiv iodine uas muaj tshuaj rau tus neeg mob Cov.
Thaum cev xeeb tub, Merifatin yuav tsum noj nrog kev saib xyuas zoo.
Yuav noj Merifatin li cas?
Cov khoom lag luam yog npaj rau kev siv qhov ncauj. Thawj koob tshuaj thaum lub sij hawm monotherapy rau hauv cov neeg laus cov neeg mob yog 500 mg 1-3 zaug ib hnub. Qhov koob tshuaj tuaj yeem hloov mus rau 850 mg 1-2 zaug ib hnub. Yog tias muaj kev xav tau, tom qab ntawd cov koob tshuaj tau ntxiv rau 3000 mg rau 7 hnub.
Cov menyuam yaus hnub nyoog tshaj 10 xyoo raug tso cai noj 500 mg lossis 850 mg ib hnub ib zaug lossis 500 mg 2 zaug ib hnub. Cov koob tshuaj muaj peev xwm nce ntxiv hauv ib lis piam mus rau 2 g ib hnub rau 2-3 koob. Tom qab 14 hnub, tus kws kho mob kho cov tshuaj noj ntau npaum li cas, suav nrog cov ntshav qab zib hauv cov ntshav.
Thaum ua ke nrog cov tshuaj insulin, qhov tshuaj ntawm Merifatin yog 500-850 mg 2-3 zaug ib hnub.
Nrog ntshav qab zib
Thaum muaj ntshav qab zib, metformin raug coj ua raws li cov txheej txheem uas tus kws kho mob ua, suav nrog tus yam ntxwv ntawm tus neeg mob thiab cov txiaj ntsig ntawm kev soj ntsuam tag nrho.
Qhov tshwm sim phiv ntawm Merifatin
Muaj qee kis, muaj qhov tshwm sim tsis zoo tshwm sim. Kev tswj hwm ntawm cov ntsiav tshuaj thaum muaj kev phiv tshuaj nres thiab tus kws kho mob tuaj ntsib.
Kev kho mob txoj hnyuv
Los ntawm cov hauv plab zom mov, xeev siab, ntuav, raws plab, mob plab thiab tsis qab los noj mov yog cai. Cov tsos mob tsis zoo txaus siab tshwm sim ntawm thawj theem ntawm kev kho mob thiab ploj mus rau yav tom ntej. Txhawm rau kom tsis txhob sib tsoo nrog lawv, nws yog ib qho tsim nyog yuav tsum pib nrog qhov tsawg kawg kev noj tshuaj thiab maj mam nce nws.
Hematopoietic plab hnyuv siab raum
Tsawg tsawg zaus, muaj kev ua txhaum ntawm qhov nqus ntawm cov vitamin B12.
Los ntawm ib sab ntawm cov metabolism
Qee zaum cov tshuaj ua rau muaj kev loj hlob ntawm cov kab mob lactic acidosis.
Kev ua xua
Kev ua xua tshwm sim nyob rau hauv daim ntawv ntawm khaus, tawm pob thiab erythema.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Nrog rau cov tshuaj tua kab mob, cov tshuaj tsis cuam tshuam loj heev rau kev tswj hwm kev thauj khoom thiab kev ua tiav ntawm kev nqis tes ua uas yuav tsum tau muaj kev xav ntau ntxiv thiab cov kev xav psychomotor sai. Dua li ntawm qhov no, tus neeg mob yuav tsum paub txog cov tsos mob ntawm kev mob hypoglycemia thiab ceev faj.
Cov lus qhia tshwj xeeb
Thaum kho, nws yog qhov yuav tsum tau soj ntsuam cov qib ntawm cov piam thaj hauv cov ntshav.
Thaum kho, nws yog qhov yuav tsum tau soj ntsuam cov qib ntawm cov piam thaj hauv cov ntshav.
Siv rau lub sijhawm qub
Hauv cov neeg mob tom qab 60 xyoo, muaj kev pheej hmoo ntawm kev tsim ntawm cov kab mob lactic acidosis, yog li cov tshuaj yuav tsum tsis txhob nyob hauv pawg neeg mob no.
Txiag tej menyuam
Cov tshuaj tsis raug rau cov menyuam yaus hnub nyoog qis dua 10 xyoo.
Siv thaum cev xeeb tub thiab lactation
Nws tsis pom zoo kom noj cov ntsiav tshuaj thaum nqa tus menyuam thiab kev pub niam mis, txij li cov tshuaj nquag nkag mus rau hauv tus menyuam thiab mis niam. Txoj kev kho tuaj yeem kho tau yog tias qhov txiaj ntsig ntawm kev kho mob tshaj qhov txaus ntshai ntawm cov teeb meem hauv tus menyuam.
Daim ntawv thov rau lub raum khiav tsis zoo
Nws yog txwv tsis pub siv cov yeeb tshuaj thaum muaj kev ua tsis zoo ntawm lub cev.
Siv rau lub siab ua haujlwm tsis zoo
Nws yog contraindicated los nqa tawm kev kho mob nrog Merifatin thaum muaj teeb meem ntawm daim siab ua haujlwm.
Nws yog contraindicated los nqa tawm kev kho mob nrog Merifatin thaum muaj teeb meem ntawm daim siab ua haujlwm.
Kev noj tshuaj ntau dua ntawm Merifatin
Yog tias koj ua txhaum qhov kev pom zoo ntawm cov tshuaj, ib qho kev siv ntau tshaj yuav tshwm sim, ua rau pom kev sib txuas ua kom lactic acidosis. Lawv tso tseg tsis noj tshuaj thiab sab laj tus kws tshaj lij uas sau tshuaj rau cov tsos mob kev kho mob thiab hemodialysis.
Kev cuam tshuam nrog lwm yam tshuaj
Nws yog txwv tsis pub txuas cov tshuaj metformin nrog iodine-muaj cov tshuaj radiopaque. Nrog ceev faj, lawv noj cov tshuaj Merifatin nrog Danazole, Chlorpromazine, glucocorticosteroids, diuretics, txhaj tshuaj beta2-adrenergic agonists thiab antihypertensive cov neeg sawv cev, tshwj tsis yog rau inhibitors ntawm agiotensin hloov enzyme.
Ib qho kev nce ntxiv ntawm cov tshuaj metformin hauv cov ntshav tau pom thaum lub sijhawm cuam tshuam nrog cov tshuaj cationic, cov uas amiloride. Kev nqus ntawm metformin ntau ntxiv tshwm sim thaum ua ke nrog nifedipine. Hormonal contraceptives txo cov nyhuv hypoglycemic ntawm cov tshuaj.
Cawv tau zoo
Thaum kho lub sijhawm, nws yog txwv tsis pub haus dej haus cawv thiab cov khoom lag luam uas muaj ethanol, vim qhov pheej hmoo ntawm cov kab mob lactic acidosis.
Analogs
Yog tias tsim nyog, siv cov tshuaj zoo sib xws:
- Hnab Ntim Hnab;
- Glycon;
- Glucophage;
- Kab Yeeb;
- Siafor;
- Rau menyuam yaus.
Tus kws tshwj xeeb xaiv cov tshuaj analogue, suav txog qhov mob hnyav ntawm tus kabmob.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Txhawm rau yuav tshuaj hauv chaw muag tshuaj, koj yuav tsum tau yuav tshuaj.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Cov tshuaj tsis tuaj yeem muas tsis tas cov tshuaj los ntawm kws kho mob.
Nqe rau Merifatin
Tus nqi ntawm cov tshuaj yog nyob ntawm txoj cai nqe ntawm lub tsev muag tshuaj thiab qhov nruab nrab 169 rubles.
Cia rau cov neeg mob rau cov tshuaj
Lub pob nrog cov ntsiav tshuaj muab tso rau hauv qhov chaw tsaus, qhuav thiab nkag tsis tau rau cov menyuam uas muaj qhov kub tsis dhau + 25 ° C.
Hnub tas sij hawm
Cov tshuaj yeeb nws khaws cia nws lub thaj tsam rau 3 xyoos txij li hnub ntawm kev tsim khoom, raug rau cov cai tswj kev khaws cia. Tom qab hnub tas sij hawm, cov tshuaj raug pov tseg.
Chaw tsim tshuaj paus
Pharmasintez-Tyumen LLC yog koom nrog kev tsim tshuaj yaj yeeb hauv Lavxias.
Thaum kho lub sijhawm, nws yog txwv tsis pub haus dej haus cawv.
Kev tshuaj xyuas ntawm Merifatin
Konstantin, 31 xyoo, Irkutsk: "Kuv siv cov tshuaj tsis tu ncua. Tsis muaj kev cuam tshuam dab tsi. Cov nqi them. Kuv pom zoo."
Lilia, 43 xyoo, Moscow: "Lub sijhawm thaum ntxov ntawm kev kho mob Merifatin, xeev siab thiab kiv taub hau tshwm sim. Kuv tau mus ntsib kws kho mob. Nws hloov qhov ntau npaum li cas. Nws zoo siab dua."
