Amoxiclav yog kev sib txuam ntawm ob qho tshuaj: amoxicillin trihydrate thiab clavulanate. Cov tshuaj tua kab mob ua rau ntau qhov ntawm cov tsiaj txhu me me uas ua rau kis kev kis mob ntawm ntau yam plab hnyuv siab raum thiab tshuab.
ATX
J01CR02 Amoxicillin xyaw nrog beta-lactamase inhibitor.
Cov tshuaj tua kab mob ua rau ntau qhov ntawm cov tsiaj txhu me me uas ua rau kis kev kis mob ntawm ntau yam plab hnyuv siab raum thiab tshuab.
Tso cov ntawv thiab cov nyob ua ke
Amoxiclav 250 mg tuaj yeem faib ua ntsiav tshuaj lossis ncua daim ntawv hmoov.
Cov ntsiav tshuaj muaj cov xaum zaj duab xis, lawv muaj xim daj-dawb, octagonal zoo li duab, convex ntawm ob sab. Txhua tus muaj 250 mg ntawm amoxicillin thiab 125 mg ntawm clavulanic acid potassium ntsev.
Lub hmoov yuav dawb los yog daj hauv cov xim, qhov kev ncua yuav tsum yog homogeneous. 5 ml ntawm cov tshuaj, ua raws li cov lus qhia rau kev siv, muaj 250 mg ntawm amoxicillin thiab 62,5 mg ntawm cov kua qaub.
Hauv cov chaw muag tshuaj, muaj ob daim ntawv ntxiv ntawm cov tshuaj siv - cov hmoov siv los txhaj tshuaj, thiab cov ntsiav tshuaj dispersible. Tab sis cov foos no muaj ntau yam sib txawv ntawm cov tshuaj nquag.
Pharmacological kev txiav txim
Ntsiav tshuaj thiab hmoov muaj cov kab mob bactericidal, i.e. muaj peev xwm tua tau cov kab mob me. Cov tshuaj no ua rau ntau cov kab mob, yog li ntawd, hais txog cov tshuaj tua kab mob ntau.
Amoxicillin yog ib hom penicillin (semisynthetic) uas tsis tiv taus beta-lactamases zais cia los ntawm qee cov kab mob. Nws cov nyhuv yog vim yog qhov inhibition hauv microorganism ntawm enzymes koom nrog hauv biosynthesis ntawm peptidoglycan. Raws li kev txheeb ze rau cov tshuaj tua kab mob, lub cell phab ntsa ntawm cov kab mob raug rhuav tshem, uas ua rau tuag ntawm tes.
Ntsiav tshuaj thiab hmoov muaj cov kab mob bactericidal, i.e. muaj peev xwm tua tau cov kab mob me.
Clavulanate tsis siv cais, vim hais tias cov kua qaub nws tus kheej tsis muaj lub zog tiv thaiv kab mob, tab sis nws nthuav cov txiaj ntsig ntawm amoxicillin vim nws cov nyhuv ntawm beta-lactamases.
Hauv lub cev, cov tshuaj muaj cuam tshuam rau ob tus kab (+) thiab cov kab mob gram-tsis zoo:
- Staphylococci.
- Klebsiella.
- E. coli.
- Pfeiffer's wand.
- Cov sawv cev ntawm hom genus Enterobacter.
- Moraxellus cataralis.
Cov tshuaj tseem muaj cov haujlwm tawm tsam qee yam kab mob, xws li bordetella, brucella, clostridia, gardnerella, yersinia, chlamydia, treponema, thiab lwm yam, tab sis qhov kev ua no tseem tsis tau muaj pov thawj.
Cov Tshuaj Pharmacokinetics
Ob qhov tshuaj yeeb dej caw muaj cov yam ntxwv zoo sib xws. Lawv muaj soluble heev hauv dej thiab kev daws teeb meem nrog kev taw qhia ntawm lub cev acidity. Yog li, cov tshuaj tau muab nqus sai sai rau hauv cov ntshav los ntawm cov plab hnyuv plab zom mov, nws cov kev noj qab nyob zoo mus txog 70%. 60 feeb tom qab kev tswj hwm, qhov concentration ntawm cov tshuaj yog txo los ntawm ib nrab.
Cov tshuaj yuav zoo tshaj yog pom thaum pib noj mov.
Cov tshuaj yuav zoo tshaj yog pom thaum pib noj mov.
Amoxiclav tsis muaj peev xwm txhawm rau nkag los ntawm cov hlab ntsha mus rau hauv lub hlwb (yog tias tsis muaj paib tshwm sim hauv nws lub plhaub). Tab sis dhau ntawm cov placenta, cov tshuaj nkag mus, nws tseem kis mus rau niam mis. Amoxicillin trihydrate tshem tawm ntawm lub cev los ntawm lub raum, thiab clavulanate nrog quav thiab tso zis.
Kev ntsuas rau siv
Cov tshuaj yog siv rau hauv kev kho mob kis tus kab mob los ntawm kev ua si ntawm cov kab mob tshuaj tua kab mob:
- Cov mob ENT - mob siab thiab ntev mob ntsws, mob otitis media, tonsillitis, tonsillitis, sinusitis, pharyngitis, thiab lwm yam.
- Txhab ntawm lub ntsws thiab tsob ntoo bronchial - mob ntsws thiab mob ntsws.
- Cov kab mob genitourinary thiab gynecological (piv txwv li, endometritis, prostatitis, cystitis).
- Txhab ntawm cov tawv nqaij thiab cov ntaub so ntswg sib txuas.
- Muaj mob rau hauv lub qhov ncauj (odontogenic).
- Tus mob cholecystitis thiab cholangitis.
Cov Yuav Tsum Muaj
Cov tshuaj tua kab mob tsis tau sau tseg rau kev phiv tshuaj rau cov feem ntawm cov tshuaj, suav nrog penicillin.
Yog tias tus neeg mob muaj keeb kwm muaj cov kab mob siab siab uas tau tsim nrog cov tshuaj, ces tus kws kho mob yuav tsum sau lwm cov tshuaj ntxiv.
Nrog pathologies ntawm lub plab zom mov, ua haujlwm tsis zoo ntawm hepatocytes, qib 3 lub raum tsis ua haujlwm, cev xeeb tub thiab pub niam mis, cov tshuaj tau tawm nrog ceev faj. Thaum noj nrog tshuaj uas txo cov ntshav coagulation, cov neeg mob tus mob yuav tsum tau saib xyuas.
Yuav noj Amoxiclav 250 li cas
Cov ntsiav tshuaj thiab ncua ntawm cov hmoov noj yog coj qhov ncauj. Qhov ntau npaum li cas thiab kev noj tshuaj yog txiav txim los ntawm tus kws kho mob raws li tus neeg qhov yam ntxwv ntawm tus neeg mob. Txoj kev kawm no tuaj yeem ntev txog 2 asthiv. Ib qho kev nce hauv lub sijhawm kho yog nqa tawm tom qab kev kuaj mob lub cev thiab kev ntsuas.
Yuav ua li cas dilute
Lub hmoov yog diluted nrog dej huv huv 20-25 ° C. Ua ntej yuav ntxiv dej, lub raj mis yuav tsum tau co kom khov, tom qab uas ntxiv 85 mg ntawm kua hauv ob zaug faib. Tom qab txhua ntxiv dej, qhov kev ncua yuav tsum tau muab co kom zoo kom yaj cov hmoov. Qhov tshwm sim yuav tsum yog ib homogeneous tshuaj ntawm cov xim dawb lossis daj-daj.
Cov khoom tiav tiav tau muab khaws cia rau hauv tub yees kom ntev dua tsis pub dhau ib lub lim tiam. Ua ntej siv, nws yuav tsum raug coj mus rau chav sov, tab sis tsis rhuab. Tsis khov.
Rau qhov yooj yim ntawm kev siv ncua kev kawm, lub pipette lossis ntsuas diav yog muab tso rau hauv txhua pob hmoov.
Rau qhov yooj yim ntawm kev siv ncua kev kawm, lub pipette lossis ntsuas diav yog muab tso rau hauv txhua pob hmoov.
Koob tshuaj rau cov me nyuam
Hauv cov menyuam hnub nyoog qis dua 12-13 xyoos lossis hnyav dua 39 kg, siv tshuaj rau cov neeg laus.
Rau tus menyuam muaj hnub nyoog 6-12 xyoo, tus kws kho mob tau sau ntawv rau noj raws lub hnub nyoog, qhov hnyav thiab qhov mob hnyav. Qhov koob tshuaj txhua hnub ntawm 40 mg / kg, muab faib ua 3 daim ntawv thov, raug pom zoo.
Nws yooj yim dua rau cov menyuam preschool muab ncua kev kawm. Ib tug menyuam txog 3 hlis yog tsim nrog 15 mg / kg 2 zaug ib hnub. Cov menyuam hnub nyoog tshaj no - los ntawm 7 txog 13 mg / kg txhua 8 teev (hauv ib hnub tsis pub tshaj 40 mg / kg).
Rau cov laus
Kev txais tos yog nyob ntawm qhov mob hnyav, uas mob sib khuav thiab me me - 1 ntsiav tshuaj thaum sawv ntxov, yav tav su thiab thaum yuav mus pw. Yog tias kev kis mob hnyav, tus kws kho mob tau sau ntawv rau noj cov tshuaj 500 lossis 875 mg amoxicillin.
Tus neeg mob yuav tsum ua raws li tus kws kho mob cov lus qhia thiab tsis hloov 2 ntsiav tshuaj ntawm 250 mg nrog ib ntawm 500 mg.
Qhov siab tshaj plaws ntawm qhov kev ncua raug tiav yog 5 ml ib hnub.
Kev teem sij hawm ntawm Amoxiclav nyob rau hauv cov ntshav qab zib yog qhov tsim nyog, vim nws tiv thaiv kev kis kab mob ntawm thaj chaw ntawm daim tawv nqaij nrog lub cev tsis muaj zog.
Noj cov tshuaj rau ntshav qab zib
Amoxiclav tsis cuam tshuam rau cov ntshav qabzib, tsis muaj kev pheej hmoo ntawm kev loj hlob hyperglycemia. Lub hom phiaj ntawm cov tshuaj rau hom kab mob no tsuas yog txiav txim siab, vim nws txwv tsis pub kis rau ntawm cov tawv nqaij nrog lub cev tsis muaj zog.
Sab sij huam
Cov ntsiav tshuaj thiab hmoov muaj ib daim ntawv teev kev tsis zoo, daim ntawv tso tawm tsis cuam tshuam rau qhov ntsuas no.
Kev kho mob txoj hnyuv
Cov tsos mob ntawm dyspepsia: xeev siab txog ntuav, raws plab, mob epigastric thiab tsis qab los noj mov. Cov txheej txheem ua mob hauv lub qhov ncauj (stomatitis thiab glossitis) thiab tshem tawm ntawm tus hniav txha hniav laus. Tus mob Enterocolitis thiab hemorrhagic colitis tuaj yeem tshwm sim hauv cov hnyuv. Cov tshuaj muaj peev xwm cuam tshuam rau kev ua haujlwm ntawm lub siab, uas pom nyob rau hauv kev nce siab hauv kev ua haujlwm ntawm nws cov enzymes, kev nce siab hauv bilirubin, daj ntseg, mob siab.
Hematopoietic plab hnyuv siab raum
Txo cov lej ntawm leukocytes thiab neutrophils (thim rov qab), platelets hauv cov ntshav. Cov cim qhia ntawm kev mob ntshav qab zib (hemolytic anemia), lub sijhawm ua haujlwm ntau ntxiv. Ib qho nce ntawm cov eosinophils thiab agranulocytes.
Nruab nrab hauv lub paj hlwb
Cephalgia thiab kiv taub hau, tsis tshua muaj cramps.
Los ntawm cov kab mob zis
Tubulo-interstitial nephritis, ntshav, thiab muaju hauv zis.
Kev ua xua
Kev paub tsis meej rau ntau yam ntawm Amoxiclav tuaj yeem tshwm sim los ntawm tawm pob, khaus, ua xua vasculitis, anaphylactic ceeb, Quincke's edema.
Cov lus qhia tshwj xeeb
Siv tshuaj tua kab mob yuav tsum tau nrog kev saib xyuas lub cev ua haujlwm.
Yog tias muaj cov cim qhia kev kuaj ntshav siab, kws kho mob hloov qhov kev kho mob.
Kev noj tshuaj tiv thaiv kab mob tuaj yeem hloov kho qhov sib txuam ntawm txoj hnyuv thiab lub paum ntawm qhov paum. Yog li, tus kws kho mob tuaj yeem sau tshuaj ntxiv txhawm rau tiv thaiv cov mob xws li dysbiosis thiab candidiasis.
Cawv tau zoo
Tsis muaj ntaub ntawv hais txog cov nyhuv ntawm cawv ntawm cov tshuaj pharmacokinetics ntawm cov tshuaj. Tab sis cov kws kho mob tsis pom zoo kom haus cawv thaum haus dej cawv. Lub cev tsis muaj zog los ntawm kev kis tus kab mob, thiab lub siab thiab lub raum siv lub tshuab ua ob zaug hauv cov txheej txheem ntawm kev cuam tshuam thiab tshem tawm cov metabolites ntawm cawv thiab tshuaj.
Cov kws kho mob tsis pom zoo kom haus cawv thaum haus dej cawv.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Vim tias qhov tshwm sim tsis zoo ntawm lub hauv paus ntawm lub paj hlwb, cov haujlwm uas xav kom muaj lub siab xav tau nrog kev ceev faj thiab nce kev mloog.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj ua ke ntawm cov tshuaj no hla lub hno thiab nkag mus rau niam mis, yog li Amoxiclav yog tus kws kho mob tsuas yog muaj txiaj ntsig ntawm kev kho mob tshaj qhov txaus ntshai.
Siv rau lub siab ua haujlwm tsis zoo
Rau cov neeg mob uas muaj daim siab pathologies, cov tshuaj tau tawm los, tab sis thaum kho, tus kws kho mob yuav tsum saib xyuas lub cev ua haujlwm los ntawm kev ntsuas kev ntsuas.
Daim ntawv thov rau lub raum khiav tsis zoo
Nrog lub teeb meem me me ntawm kev tsis txaus thiab creatinine tshem tawm ntau dua 30 ml / min, qhov koob tshuaj tsis hloov. Cov kab mob loj heev xav tau kev ceev faj thiab koob tshuaj hloov kho los yog txo tus zaus kom tswj hwm.
Lub raum mob loj ntxiv yuav tsum muaj kev ceev faj thiab koob tshuaj hloov kho lossis kom txo qis hauv cov thawj coj.
Noj ntau dhau
Kev tuag nrog kev noj ntau dhau tsis tau piav qhia. Cov tsos mob ntawm kev noj ntau dua yog qhov tsis xis nyob hauv plab, raws plab thiab ntuav. Ntxhov siab vim thiab pw tsaug zog teeb meem yuav tshwm sim, thiab nyob rau hauv raug mob cais tau qaug dab peg nrog convulsions.
Cov kev mob tshwm sim yog nqa hauv tsev kho mob. Yog tias tsawg dua 4 teev tau dhau mus tom qab kev tswj hwm, tom qab ntawd lub plab thiab lub voos ntawm cov pa roj carbon ntau. Hemodialysis siv tau.
Kev cuam tshuam nrog lwm yam tshuaj
Yog tias siv ua ke nrog cov vitamin C, tom qab ntawd nqus cov tshuaj los ntawm kev mob plab hnyuv tuaj yeem nce ntxiv. Hauv kev sib piv, antacids, laxatives thiab aminoglycosides txo qis kev nkag ntawm cov tshuaj mus rau hauv cov hlab ntshav.
Cov tshuaj uas inhibit qhov zais cia ntawm tubules nce qhov kev xav ntawm Amoxiclav nyob rau hauv cov ntshav, txij li nws tau tshem los ntawm ob lub raum.
Kev sib piv nrog metatrexate tsis zoo, vim hais tias amoxiclav nce nws lom.
Nws tsis pom zoo kom sau ntawv nrog rifampicin (antagonists), sulfonamides, tetracyclines thiab macrolides, vim tias tag nrho cov tshuaj no tiv thaiv cov nyhuv ntawm Amoxiclav.
Cov poj niam ntawm kev muaj me nyuam lub hnub nyoog yuav tsum tau piav qhia tias Amoxiclav cuam tshuam tsis zoo ntawm qhov ncauj ntawm qhov ncauj, yog li, lwm txoj hauv kev tiv thaiv kev xeeb tub yuav tsum tau siv thaum kho.
Cov poj niam ntawm kev ua me nyuam lub hnub nyoog yuav tsum tau piav qhia tias Amoxiclav cuam tshuam tsis zoo rau qhov kev cuam tshuam ntawm qhov ncauj.
Cov npe ntawm Amoxiclav 250
Kev lag luam kws tshuaj muaj ntau yam qauv ntawm cov tshuaj:
- Flemoklav Solutab;
- Augmentin Syrup;
- Amoxiclav Quicktab;
- Sumamed;
- Lub Ecoclave;
- Panklav;
- Clamosar;
- Arlet
- Rapiclav;
- Novaklav;
- Baktoklav;
- Fibell;
- Medoclave;
- Amovicomb;
- Betaclava;
- Amoxicillin trihydrate + Potassium clavulanate.
- Ranklav;
- Foraclav.
Hloov cov tshuaj nrog ib qho zoo sib xws yuav tsum yog kws kho mob ua.
Augmentin yog qhov piv txwv ntawm Amoxiclav.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Daim ntawv yuav tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Txawm hais tias qee lub tsev muag tshuaj tseem muag cov tshuaj uas tsis muaj ntaub ntawv los ntawm kws kho mob, txhua xyoo txoj cai nruj tswj hwm.
Nqi
Tus nqi nruab nrab ntawm cov hmoov yog 298 rubles, qhov ntim ntawm cov ntsiav tshuaj yog 245 rubles.
Cia rau cov neeg mob Amoxiclav 250
Cov ntsiav tshuaj thiab hmoov yuav tsum muab tso rau ntawm chav sov thiab hauv qhov chaw tsaus rau cov menyuam yaus siv tsis tau. Qhov kev muab tshem tawm yog muab cia rau hauv tub yees.
Hnub tas sij hawm
2 xyoos Qhov npaj tos tawm yog 7 hnub.
Amoxiclav 250 Xyuas
Cov kws kho mob
Valery, kws kho mob, Shlisselburg
Cov tshuaj niaj hnub no siv dav hauv ntau qhov chaw ntawm cov tshuaj. Kev tiv thaiv zoo rau ntau cov kabmob, nrog rau cov tshuaj tua kabmob penicillin-tawm tsam. Nws yog tawm tag nrho los ntawm lub cev, tsis nkag rau tus txha caj qaum thiab dhau los ntawm BBB, yog li qhov kev pheej hmoo ntawm kev phiv los ntawm lub hauv nruab nrab lub paj hlwb yog qhov tsawg heev.
Txawm hais tias qhov tseeb tias tshuaj zoo thiab muaj kev nyab xeeb, Kuv xav ceeb toom cov neeg mob kom tsis txhob sau nws rau lawv tus kheej. Kev tswj tsis siv tshuaj tua kab mob tuaj yeem ua rau muaj kev txhim kho ntawm teeb meem, superinfection thiab rov tshwm sim ntawm cov tshuaj tiv thaiv uas yuav nyuaj rau kev sib ntaus.
Eugene, kws kho mob hlwb, Nizhny Novgorod
Hauv cov tshuaj niaj hnub, kev kho cov kab mob sib kis tau pib nrog kev tswj hwm ntawm qhov ua tau zoo, tab sis kev siv tshuaj tiv thaiv kev nyab xeeb tshaj plaws nrog kev ua kom dav. Ib cov tshuaj yog Amoxiclav. Cov ntawv tso cai sib txawv tso cai rau koj noj kom yog yog thaum muab rau cov menyuam. Kev phiv tshuaj yog qhov tsawg.
Natalia, kws kho mob zawv plaub hau, St. Petersburg
Rau qee qhov laj thawj, cov poj niam pib tshwm sim thaum txais tos, uas txiav txim siab los ntawm nws tus kheej rov qab los ntawm cov mob hnyav ntawm pob txuv nrog amoxicillin. Raws li qhov tshwm sim, tsis muaj ib qho tshwm sim, tab sis lawv kuj khwv tau lawv tus kheej phiv tawm nyob rau hauv daim ntawv ntawm eczema, dermatitis thiab urticaria. Amoxiclav yog tshuaj tiv thaiv zoo rau ntau yam mob, tab sis kho pob txuv kho tau sib txawv.
Cov neeg mob
Tatyana, 35 xyoo, Moscow
Ib qho cuab yeej zoo uas pab tau tag nrho tsev neeg, thaum tsis kim tshaj plaws ntawm cov tshuaj tua kab mob. Tus me nyuam zam tau zoo thaum nws tseem me, lawv tau muab ncua, vim nws tsis yooj yim txiav cov ntsiav tshuaj mus rau ntau qhov chaw. Tus txiv tau kho nrog cov ntsiav tshuaj rau mob ntsws zoo hnoos, nrog rau lwm cov tshuaj. Tab sis nws tsis haum rau txhua tus, piv txwv li, tus phooj ywg muaj kev tsis haum, nws pib mob taub hau thiab ntuav.
Larisa, 55 xyoo, Arkhangelsk
Kuv zoo siab tias nyob hauv cov khw muag tshuaj lawv tau muag cov tshuaj tua kab mob yam tsis muaj daim ntawv xaj tshuaj. Txwv tsis pub, kuv tus txiv uas mob prostatitis tsis tuaj yeem yaum kom mus cuag kws kho mob, nws tau sim kho nws tus kheej los ntawm Is Taws Nem. Tus kws kho mob tau ua qhov kev soj ntsuam nrog kev tshuaj ntsuam thiab kho mob nrog rau, suav nrog Amoxiclav. Thaum ntxov, kuv tus txiv nqos cov ntsiav tshuaj tau ntau lub hlis, tab sis twb nyob hauv thawj lub lim tiam ntawm kev kho mob nws pom kev txhim kho thiab tau pw tsaug zog zoo. Nws haus cov tshuaj tua kab mob mus ntev li ob lub lis piam, lub sijhawm no tsuas muaj ib qho xeev ntuav vim nws tau noj tshuaj ntau xyoo ua ntej noj mov. Tsis muaj lwm cov kev mob tshwm sim.
