Plevilox yog cov tshuaj tua kabmob bactericidal antimicrobial nrog rau kev pom zoo los ntawm pawg fluoroquinolones ntawm plaub tiam neeg.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Moxifloxacin (Moxifloxacin).
Plevilox yog cov tshuaj tua kabmob bactericidal antimicrobial nrog rau kev pom zoo los ntawm pawg fluoroquinolones ntawm plaub tiam neeg.
ATX
Qhov txheej txheem ATX yog J01MA14, uas txhais tau hais tias cov tshuaj yog koom nrog cov pab pawg tshuaj tua kab mob muab los ntawm quinolone.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, zaj duab xis-txheej. Cov ntsiav tshuaj tau ntim rau hauv cov hlwv tso rau hauv thawv ntawv thawv.
Cov tshuaj nquag siv ntawm Plevilox yog moxifloxacin hydrochloride hauv ib koob tshuaj ntawm 400 mg. Microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, magnesium stearate, copovidone, polydextrose, polyethylene glycol, caprylic thiab capric acid triglycerides, titanium dioxide, varnish daj thiab xim daj hlau oxide yog siv los ua cov tshuaj tiv thaiv kab mob.
Pharmacological kev txiav txim
Cov tshuaj muaj peev xwm txwv tsis pub cov tshuaj topoisomerase IV thiab DNA gyrase - cov enzymes ua lub luag haujlwm rau kev rov ua dua, pauv, kho thiab rov ua kom tiav cov kab mob DNA. Nws muaj cov kab mob bactericidal vim muaj peev xwm ntawm moxifloxacin cuam tshuam kev cuam tshuam DNA hluavtaws ntawm cov kab mob hlwb.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, zaj duab xis-txheej.
Nquag tiv thaiv cov kab mob gram-positive thiab gram-tsis zoo, nrog rau cov kab mob ntawm anaerobic, acid-resistant thiab atypical hom, xws li Legionella spp., Chlamydia spp. thiab Mycoplasma spp. Kev tiv thaiv zoo tiv thaiv cov kab mob tiv thaiv kom tsis txhob raug beta-lactams thiab macrolides. Nws ua rau tawm tsam feem ntau ntawm cov kab mob me: gram-zoo Staphylococcus aureus (suav nrog tshuaj tiv thaiv kab mob methicillin), Streptococcus pneumoniae (suav nrog kev tawm tsam penicillin thiab macrolides), Streptococcus pyogenes A-pawg.
Cov Tshuaj Pharmacokinetics
Cov tshuaj muaj cov cim rau qib siab ntawm kev nqus, tsis hais txog lub sijhawm noj mov, nws qhov taw qhia txog qhov tsis tuaj yeem yog kwv yees li 90-91%.
Kev tswj hwm ib qhov ncauj ntawm moxifloxacin tso cai rau koj kom ua tiav Cmax hauv cov ntshav ntawm 3.1 mg / l, tsis pub dhau 30 feeb - 4 teev.
Pharmacokinetics yog tso tawm nrog ib koob ntawm 50-1200 mg thiab 10-hnub txoj kev kho nrog koob tshuaj 600 mg / hnub.
Cov chaw ntawm qhov kev xav ntau tshaj ntawm cov tshuaj yog lub ntsws, alveolar macrophages, cov qog ua pa ntawm cov hlab ntsha thiab bronchi.
Cov tshuaj tuaj yeem tawm hauv cov khoom tsis tseem ceeb hauv lub cev thiab hauv nws cov ntawv qub nrog zis thiab quav.
Tus tub los ntxhais thiab hnub nyoog tsis cuam tshuam rau qhov chaw txiav tshuaj (kuaj tsis tau ua hauv menyuam yaus), thiab tsis cuam tshuam rau lub raum tsis ua haujlwm ntxiv.
Kev ntsuas rau siv
Cov tshuaj yog tawm hauv kev kho mob kis tau tus mob cuam tshuam rau sab sauv thiab sab ua pa ntawm txoj hlab pa: kis mob siab ntsws, mob ntsws zej zog muaj mob ntsws thiab ua rau mob ntsws txhaws ntev. Tsis tas li, cov tshuaj yeeb tshuaj qhia pom tias muaj txiaj ntsig zoo hauv kev kho mob kis mob ntawm daim tawv nqaij thiab cov nqaij mos.
Cov Yuav Tsum Muaj
Nws yog txwv tsis pub siv rau hauv menyuam yaus thiab tub ntxhais hluas hnub nyoog qis dua 18 xyoo, suav nrog, thaum cev xeeb tub, lactation thiab hypersensitivity rau moxifloxacin thiab ib qho kev zam nyob rau hauv muaj pes tsawg leeg Plevilox.
Nrog saib xyuas
Kev saib xyuas tshwj xeeb hauv kev teem sij hawm Plevilox yuav tsum muaj keeb kwm ntawm qhov muaj mob txaus, mob siab rau lub siab, ua kom ntev ntawm QT ntu, bradycardia, myocardial ischemia, raws plab thiab pseudomembranous colitis.
Cov yeeb tshuaj no yog txwv rau kev siv rau cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo suav nrog.
Vim kev paub tsis txaus nrog rau kev thov thiab cov kev tshawb fawb txog kev tsis tu ncua, kev ceev faj yuav tsum tau muab tshuaj rau cov neeg mob uas nyob ntawm hemodialysis. Nyob rau hauv kev kho kom zoo ib yam nrog glucocorticosteroids thiab tshuaj uas ua rau qeeb ntawm kev coj ua ntawm lub siab nqaij (antiarrhythmics, tricyclic antidepressants, antipsychotics), kev saib xyuas tshwj xeeb yog tsim nyog.
Yuav ua li cas noj Plevilox
Siv ncauj ntawm ncauj 1 zaug nyob rau ib hnub rau ntawm 400 mg. Lub sijhawm kho yog nyob ntawm tus kabmob:
- nyob rau hauv theem ntawm exacerbation ntawm mob ntsws - ntev 5 hnub;
- nrog cov kab mob kis hauv lub zej zog - 10 hnub;
- nrog mob siab mob ntsws, mob rau daim tawv thiab cov nqaij mos - 7 hnub.
Nrog ntshav qab zib
Cov kev tshawb fawb pom tias kev kho mob fluoroquinolone ua rau muaj kev pheej hmoo ntau ntxiv rau cov mob ntshav qab zib mellitus, thiab tshwj xeeb tshaj yog kev loj hlob ntawm dyslexemia. Kev teem caij siv tshuaj tua kab mob ntawm lwm cov chav kawm raug pom zoo: beta-lactams thiab macrolides.
Txawm li cas los xij, hauv qee kis (piv txwv li, nrog kev sib kis kis mob ntawm thaj chaw ntawm tus xeeb ceem ntawm cov neeg mob ntshav qab zib), kev siv cov tshuaj no tsuas yog ua kom raug cai. Hauv kev phais, cov pathologies yog qhov tshwm sim feem ntau uas tsis muaj qhov ua rau mob siab, uas ntau qhov kev saib xyuas tau them rau kev siv tshuaj tua kab mob kom txaus (suav nrog cov tshuaj muaj moxifloxacin).
Plevilox kev kho ntxiv muaj kev pheej hmoo ntawm kev phiv hauv ntshav qab zib.
Phiv los ntawm Pleviloksa
Los ntawm cov leeg nqaij thiab pob txha sib txuas
Tej zaum cov tsos mob ntawm mob nraub qaum, kev txhim kho ntawm arthralgia thiab myalgia.
Kev kho mob txoj hnyuv
Kev mob tshwm sim los ntawm lub plab zom zaws yog qhia los ntawm kev mob plab, xeev siab, raws plab, ntuav, dyspepsia, flatulence, cem quav, nce kev ua haujlwm ntawm hepatic transaminases, distortion ntawm saj hnov.
Hematopoietic plab hnyuv siab raum
Muaj sijhawm los ua tus mob leukopenia, eosinophilia, thrombocytosis, thrombocytopenia thiab ntshav liab.
Nruab nrab hauv lub paj hlwb
Cov kev mob tshwm sim los ntawm lub hauv nruab nrab hauv lub paj hlwb tau tshwm sim hauv txoj kev kiv taub hau, pw tsaug zog, tshee poob siab, nce siab, asthenia, mob taub hau, tshee tshee, caj dab, mob caj pas, mob plab, tsis meej pem thiab muaj kev nyuaj siab.
Cov kev mob tshwm sim ntawm Plevilox los ntawm lub hauv nruab nrab hauv lub paj hlwb yog pom ntawm daim ntawv ntawm kiv taub hau.
Ntawm ib sab ntawm daim tawv nqaij
Cov pob khaus ntawm daim tawv nqaij, tsis tshua muaj tshwm sim, mob ntsws nettle ua tau.
Los ntawm genitourinary system
Muaj kev pheej hmoo ntawm candidiasis thiab vaginitis.
Los ntawm cov hlab plawv system
Muaj peev xwm nce rau hauv cov ntshav siab, tshwm sim ntawm tachycardia, peripheral edema, palpitations thiab mob hauv siab hauv siab.
Kev ua xua
Ua xua rau txoj kev ua xua thiab ua pob xua mas raug sau tseg, cov neeg mob anaphylactic ceeb yog tsis tshua muaj. Nrog rau kev lis ntshav, cov kev tawm tsam hauv zos yuav tshwm sim: mob ntawm qhov chaw txhaj tshuaj, o thiab o.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Thaum noj tshuaj, kev tsis xis nyob thiab malaise yuav xav tias, nyob rau hauv cov ntaub ntawv no, kev tswj hwm ntawm cov tswv yim tsis pom zoo.
Thaum noj tshuaj, kev tsis xis nyob thiab malaise yuav xav tias, nyob rau hauv cov ntaub ntawv no, kev tswj hwm ntawm cov tswv yim tsis pom zoo.
Cov lus qhia tshwj xeeb
Siv rau lub sijhawm qub
Tom qab lub hnub nyoog 60 xyoo, qhov kev pheej hmoo ntawm cov leeg thiab pob txha caj qaum nce ntxiv (Achilles leeg, rov qab caj npab ntawm lub xub pwg pob qij txha, caj npab ntawm tes, biceps, ntiv tes xoo, thiab lwm yam). Thaum thawj cov cim qhia ntawm kev ua tsis zoo tshwm sim, tus neeg mob yuav tsum tau so thaum so thiab lwm yam kev kho mob uas siv cov tshuaj tsis-quinolone yuav tsum tau tham.
Txiag tej menyuam
Vim tias qhov kev nyab xeeb tsis raug thiab qhov ua tau zoo ntawm cov tshuaj tsis raug hais tseg hauv cov menyuam yaus, cov hluas thiab cov hluas (txog rau 18 xyoo suav nrog). Nws yuav tsum tau yug nyob rau hauv lub siab tias cov kev tshawb fawb tau qhia ncaj qha qhov tshwm sim ntawm kev tshwm sim ntawm arthropathy ntawm kev kho mob ntawm moxifloxacin muaj cov tshuaj.
Siv thaum cev xeeb tub thiab lactation
Plevilox txoj kev kho yog qhov ua tau rau cov poj niam cev xeeb tub, yog tias nws cov txiaj ntsig muaj peev xwm ntau dua li kev pheej hmoo ntawm tus me nyuam hauv plab, vim tias kev kawm txaus thiab tswj tau zoo tseem tsis tau ua.
Thaum lub sijhawm lactation, Plevilox tswj hwm yuav tsum raug cais tawm.
Thaum lub sijhawm lactation, Plevilox yuav tsum raug cais tawm, vim nws tau ua pov thawj tias nws tuaj yeem nkag rau hauv niam mis thiab qhov cuam tshuam tsis zoo txuas ntxiv rau cov menyuam yaus thaum tseem yau.
Daim ntawv thov rau lub raum khiav tsis zoo
Nrog lub raum tsis ua haujlwm, siv nrog ceev faj.
Siv rau lub siab ua haujlwm tsis zoo
Daim siab ua haujlwm siab thiab nce qib ntawm transaminases yog contraindications rau kev tswj hwm ntawm moxifloxacin vim muaj kev paub tsawg los tsawg.
Noj tshuaj Plevilox ntau dhau
Tsis muaj ib qho tshwm sim uas tshwm sim tsis zoo tshwm sim nrog ib qho tshuaj ib zaug nrog cov tshuaj uas muaj cov tshuaj nyob hauv 2.8 g.
Kev mob hnyav tshaj yog kho tau los ntawm kev mob plab thiab siv hluav ncaig pleev. Yog tias muaj tshaj tawm, kuaj xyuas ECG yog qhov pom zoo, txij li QT ntu sijhawm ntev yog ua tau. Tus kws kho mob yuav sau ntawv tawm kev kho cov tsos mob.
Kev noj tshuaj ntau dhau ntawm Plevilox yog kho los ntawm kev ntxuav lub plab thiab siv lub tshuab hluav ncaig hluav taws xob.
Kev cuam tshuam nrog lwm yam tshuaj
Kev siv tib lub sij hawm nrog antacids, minerals thiab multivitamins ua rau kev nqus tsis tau thiab txo qhov kev xav ntawm cov tshuaj nquag hauv cov ntshav. Nrog kev kho ua ke, cov kev cuam tshuam hauv qab no raug pom zoo:
- 2 teev tom qab noj Pleviloksa;
- 4 teev ua ntej nkag.
Ua ke siv nrog lwm cov tshuaj ntawm cov chav kawm fluoroquinolone txhawb kev txhim kho ntawm cov tshuaj tiv thaiv phototoxic.
Qhov kev nqus ntawm moxifloxacin rau hauv cov hlab ntshav yog txo qis thaum noj cov tshuaj ranitidine.
Cawv tau zoo
Nws yog txwv tsis pub haus cawv thaum kho nrog plevilox vim tias muaj qhov tshwm sim ntau heev ntawm kev mob tshwm sim (feem ntau los ntawm lub hauv nruab nrab cov hlab hlwb). Tsis tas li ntawd, lub diuretic ua haujlwm ntawm ethanol tsis tso cai kom ncav cuag lub siab xav ntawm cov khoom nquag hauv cov ntshav, uas cuam tshuam tsis zoo rau cov txiaj ntsig ntawm kev kho.
Analogs
Cov qauv ntawm cov tshuaj yog:
- Avelox;
- Aquamox;
- Megaflox;
- Moxispenser;
- Moxiflo;
- Moxifloxacin;
- Rotomox;
- Simoflox;
- Ultramox;
- Heinemox.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Tsis muaj tshuaj yuav tsis kam xa.
Nqi
Tus nqi rau kev ntim cov tshuaj Lavxias ua yeeb tshuaj (5 ntsiav tshuaj) pib ntawm 500 rubles.
Cia rau cov neeg mob rau cov tshuaj
Khaws rau hauv qhov chaw tsaus, tiv thaiv los ntawm ya raws, ntawm qhov kub tsis tshaj + 25 ° C.
Hnub tas sij hawm
Rau 2 xyoos nrog kev khaws cia kom zoo.
Chaw tsim tshuaj paus
Ntawm kev muag khoom yog npaj ntawm Lavxias thiab Khab tuam ntxhab: Farmasintez OJSC (Irkutsk) thiab Plethiko Pharmaceuticals Ltd (Indore).
Xyuas
Sophia, 24 xyoos, Krasnodar
Kuv siv cov tshuaj no nrog mob siab, nws pab tau sai. Tib qho cuab yeej uas tau muab los ua kom tau txiaj ntsig, ua ntej ntawd, thiab lwm yam tshuaj siv lwm cov tshuaj tua kab mob.
Ivan, 46 xyoo, Kazan
Muaj tshwm sim ci ntsa iab nyob rau cov tshuaj no. Mob taub hau, insomnia tormented, xeev siab tau tshwm sim. Kuv xav tias kuv yuav tau siv rau nws, siv 3 hnub, tab sis tsis muaj kev txhim kho. Kuv tau mus cuag kws kho mob kom tuaj tos lwm yam ntxiv, thiab tom qab hloov nws nrog Aquamox analogue ua kev kub ntxhov, tag nrho cov tsos mob ploj mus.
Dmitry, 35 xyoo, Lyantor
Kuv muaj peev xwm kho tus mob ntsws txhaws ntev tsuas yog muaj plevilox xwb. Hauv peb lub nroog nws nyuaj rau tau txais, kom nws los ntawm Surgut, tab sis tsis khuv xim nws, txij li thaum cov nyhuv tshwm sim tam sim ntawd.
Marina, 36 xyoo, Vladivostok
Tus kws kho mob tau muab cov tshuaj no rau cov neeg mob sinusitis, hais tias nws yuav tsum ua tib zoo saib qhov tshwm sim ntawm cov kev mob tshwm sim, txij li kev kho mob tau hais tseg rau lub sijhawm cev xeeb tub. Nws yog qhov zoo uas kuv ceeb toom, vim hais tias xeev siab ua rau neeg muaj zog, tab sis kuv xav tias cov no yog kev cuam tshuam ntawm toxicosis. Thiab yog li tam sim ntawd hloov lub chaw ntawm txoj kev kho, txhua yam mus zoo.
