Ntshav qab zib MV yog ib hom tshuaj tsis zoo rau nws. Hauv nws cov ntu muaj cov khoom tshwj xeeb - hypromellose. Nws ua rau lub hauv paus ntawm hydrophilic matrix, uas, thaum sib cuam tshuam nrog kua txiv pais plab, hloov mus rau hauv ib lub gel. Vim qhov no, muaj tus du, thoob plaws ib hnub, kev tso tawm ntawm cov khoom tseem ceeb - gliclazide. Mob ntshav qab zib muaj cov roj ntsha ua tau yooj yim thiab tuaj yeem noj ib hnub ib zaug xwb. Tsis muaj dab tsi cuam tshuam rau cov rog rog, nws muaj kev nyab xeeb rau cov neeg laus thiab cov neeg uas lub raum tsis ua haujlwm.
Tshooj lus
- 1 Txheej Txheem thiab Daim Ntawv Tso Tawm
- 2 Lub Kua Muag Ntshav Qab Zib MV
- 2.1 Tshuaj Kho Mob
- 3 Qhov ntsuas qhov siv
- 4 Cov Qauv Sib Tw
- 5 Cev xeeb tub thiab pub niam mis
- 6 Cov lus qhia rau kev siv
- 7 kev phiv
- 8 Noj ntau dhau
- 9 Cuam tshuam nrog lwm cov tshuaj
- 10 Cov lus qhia tshwj xeeb
- 11 Ib Sim Neej Ntawm Cov Ntshav Qab Zib MV
- 12 Dab tsi tuaj yeem hloov tau?
- 13 Maninil, Metformin lossis Diabeton - uas yog ib qho zoo dua?
- 14 Tus nqi hauv lub tsev muag tshuaj
- 15 Ntshav Qab Zib Kev Ntsuam Xyuas
Kev Sib Sau thiab daim ntawv ntawm kev tso tawm
Diabeton MV yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj muaj ib qho kev ceeb toom thiab cov ntawv sau "DIA" "60" ntawm ob sab. Cov tshuaj phiv tshuaj yog gliklazid 60 mg. Ntu cov khoom siv: magnesium stearate - 1.6 mg, anhydrous colloidal silicon dioxide - 5.04 mg, maltodextrin - 22 mg, hypromellose 100 cP - 160 mg.
Cov tsiaj ntawv "MV" hauv lub npe ntawm Diabeton yog deciphered raws li kev hloov kho tso tawm, i.e. maj mam.
Chaw tsim tshuaj paus: Les Laboratoires Servier, Fab Kis
Lwv Tshuaj Kho Mob MV
Diabeton hais txog sulfonylureas ntawm tiam 2. Nws ua kom lub txiav npluav thiab b-hlwb muaj lub luag haujlwm rau kev tsim cov tshuaj insulin. Ua tau zoo yog tias lub hlwb ua haujlwm qee qhov. Cov tshuaj tau tom qab tshuaj ntsuam rau c-peptide, yog tias qhov txiaj ntsig tsawg dua 0.26 mmol / L.
Kev tso tawm ntawm cov tshuaj insulin thaum noj gliclazide yog ze rau lub cev kev kawm ntau li ntau tau: lub ncov ntawm kev zais cia tau rov qab los teb rau dextrose, uas nkag mus rau hauv cov ntshav los ntawm carbohydrates, tsim tawm los ntawm hormone nyob rau theem 2 yog txhim kho.
Cov Tshuaj Pharmacokinetics
Tom qab cov thawj coj ntawm lub qhov ncauj, Diabeton yuav xau tag. Ib qho kev nce ntxiv ntawm qhov kev coj ua ntawm cov tshuaj muaj sia nyob hauv cov ntshav tau ntev li 6 teev thiab tuaj yeem tswj tau ntawm qib ua tiav txog 12 teev.
Kev sib txuas lus nrog cov ntshav plasma nce mus txog 95%, qhov muab faib tawm yog 30 l. Txhawm rau kom muaj qhov ntshav plhaw tsis tu ncua 24 teev, cov tshuaj txaus los noj 1 ntsiav tshuaj 1 zaug ib hnub.
Lub rhuav tshem ntawm cov khoom yog nqa tawm hauv lub siab. Muaj mob hauv lub raum: cov tshuaj tiv thaiv kab mob yog cov zais, <1% los tawm hauv nws cov qauv. Diabeton MV yog tshem tawm ntawm lub cev los ntawm ib nrab hauv 12-20 teev.
Kev ntsuas rau siv
- Diabeton MV (60 mg) yog kws kho mob sau tseg los ntawm tus kws kho mob rau tus mob ntshav qab zib hom II, thaum tsim tshwj xeeb kev noj haus thiab kev siv lub cev tsis zoo.
- Nws kuj tseem siv los tiv thaiv tus mob ntshav qab zib: txo kev pheej hmoo mob macrovascular (mob stroke, myocardial infarction) thiab microvascular (retinopathy, nephropathy) muaj teeb meem rau cov neeg mob ntshav qab zib hom 2.
Cov Yuav Tsum Muaj
- Yam I ntshav qab zib
- intolerance rau gliclazide, sulfonylurea thiab sulfonamide derivatives, lactose;
- galactosemia, qabzib-galactose malabsorption;
- cov piam thaj ntshav siab thiab ketone lub cev;
- nyob rau hauv cov ntawv loj heev ntawm lub raum thiab hepatic tsis txaus, Diabeton yog contraindicated;
- thaum yau thiab thaum tiav hluas
- cev xeeb tub lub sijhawm;
- pub niam mis;
- cov mob uas ua rau kuaj ntshav qab zib thiab coma.
Cev xeeb tub thiab pub niam mis
Cov kev tshawb fawb txog cov poj niam hauv txoj hauj lwm tsis tau ua tiav; tsis muaj ntaub ntawv qhia txog cov teebmeem ntawm gliclazide rau tus menyuam hauv plab. Thaum lub sijhawm sim rau cov tsiaj sim, tsis muaj kev cuam tshuam hauv kev loj hlob ntawm embryonic tau sau tseg.
Yog tias cev xeeb tub tau tshwm sim thaum noj Diabeteson MV, tom qab ntawd nws raug muab tso tseg thiab hloov mus rau cov tshuaj insulin. Tib yam mus rau kev npaj. Qhov no yog qhov tsim nyog los txhawm rau txo qhov muaj feem ntawm kev loj hlob tsis ncaj ncees hauv cov menyuam.
Siv thaum pub niam mis
Tsis muaj cov ntaub ntawv pov thawj tseeb txog kev noj cov ntshav qab zib hauv cov mis thiab muaj qhov pheej hmoo ntawm kev txhim kho hypoglycemic hauv cov menyuam mos, nws yog txwv thaum lub sijhawm lactation. Thaum tsis muaj lwm txoj hau kev rau qhov laj thawj twg, lawv raug xa mus rau khoom noj pub mis.
Cov lus qhia rau kev siv
Koos loos MV no tsuas yog tso cai los ntawm cov laus xwb. Kev txais tos yog nqa 1 zaug nyob rau ib hnub thaum sawv ntxov nrog zaub mov noj. Qhov kev siv tshuaj txhua hnub tau teeb tsa los ntawm tus kws kho mob, nws qhov siab tshaj plaws yuav ncav cuag 120 mg. Ib lub thauv lossis ib nrab ntawm nws raug muab ntxuav nrog lub khob ntawm dej huv. Tsis txhob zom thiab zom.
Yog tias koj hla 1 koob, koob tshuaj ob zaug tsis raug txais.
Thawj zaug muab tshuaj
Thaum pib ntawm kev kho mob, nws yog ib nrab ntawm cov ntsiav tshuaj, i.e. 30 mg Yog tias tsim nyog, cov koob tshuaj ntawm Tus Mob Ntshav Qab Zib MV maj mam nce mus rau 60, 90 lossis 120 mg.
Kev noj tshuaj tshiab yog muab coj los txiav txim tsis dhau 1 lub hlis tom qab sau ntawv dhau los ua ntej. Qhov kev zam tshwj xeeb yog cov neeg uas cov ntshav qabzib hauv siab tsis hloov tom qab 2 lub lis piam los ntawm thawj koob tshuaj. Rau cov neeg mob zoo li no, ntau npaum li cas ntxiv tom qab 14 hnub. Rau cov neeg mob uas laus dua 65 xyoos, tsis tas yuav hloov kho.
Txais tos tom qab lwm cov tshuaj tiv thaiv kab mob
Cov koob tshuaj ntawm cov tshuaj dhau los thiab lub sijhawm ntawm lawv cov excretion raug suav nrog. Thaum pib, qhov ntau npaum ntawm 30 mg, nws tau kho raws li cov piam thaj hauv cov ntshav.
Yog tias Tus Mob Ntshav Qab Zib MV tau los ua qhov hloov pauv cov tshuaj nrog lub sijhawm tshem tawm ntev, cov koob tshuaj kawg tau nres rau 2-3 hnub. Qhov tshuaj tiv thaiv thawj zaug kuj yog 30 mg. Cov neeg muaj tus kab mob kuaj pom lub raum tsis xav tau kev hloov kho ntau dua.
Cov pab pawg muaj:
- Kev mob siab tsis zoo vim zaub mov tsis zoo.
- Pituitary thiab adrenal tsis txaus, lub sijhawm ua rau tsis muaj cov thyroid hormones txaus.
- Tsum tsis txhob noj cov tshuaj corticosteroids tom qab kho ntev.
- Kev mob ntshav siab rau ntawm cov hlab ntshav, txoj kev tso cov roj (cholesterol) cov plaques rau ntawm cov leeg ntshav carotid.
Sab sij huam
Thaum noj Cov Ntshav Qab Zib ua ke nrog kev noj zaub mov tsis zoo, kev qog ntshav qab zib yuav tshwm sim.
Nws cov cim:
- mob taub hau, kiv taub hau, hnov qhov tsis pom kev;
- tas li kev xav ntawm kev tshaib kev nqhis;
- xeev siab, ntuav
- qhov tsis muaj zog sab nraud, tshee hnyo rau tes, cramps;
- causally tsis chim siab, poob siab poob siab;
- insomnia lossis tsaug zog hnyav;
- tsis nco qab nrog ib tug ua rau tsis nco qab.
Cov kev tshwm sim hauv qab no uas ploj tom qab noj qab zib kuj tseem tuaj yeem kuaj:
- Dhau hws, tawv nqaij yuav lo rau qhov kov.
- Kev kub siab, palpitations, arrhythmia.
- Ntse mob hauv siab hauv siab vim tsis muaj ntshav txaus.
Lwm qhov tsis xav tau:
- Cov tsos mob dyspeptic (mob plab, xeev siab, ntuav, raws plab lossis quav tawv);
- kev tsis haum tshuaj thaum noj ntshav qab zib;
- txo qis hauv leukocytes, platelets, tus naj npawb ntawm granulocytes, hemoglobin concentration (kev hloov pauv yog thim rov qab);
- nce kev ua si ntawm hepatic enzymes (AST, ALT, alkaline phosphatase), kis mob cais tawm ntawm tus kab mob siab;
- kev tsis sib haum ntawm cov txheej txheem pom yog nyob rau thaum pib ntawm kev kho mob ntshav qab zib.
Noj ntau dhau
Nrog rau kev noj tshuaj ntau dhau ntawm Diabetone Yog tias nco qab tsis zoo thiab tsis muaj mob hnyav, ces koj yuav tsum haus kua txiv qab zib lossis tshuaj yej nrog qab zib. Yog li cov ntshav qab zib hauv lub cev tsis tshua rov tshwm sim, koj yuav tsum nce cov nyiaj carbohydrates hauv cov zaub mov noj lossis txo qhov ntau npaum ntawm cov tshuaj.
Yuav tsum tau pw hauv tsev kho mob thaum qhov mob ntshav qis ntau heev. Ib qho 50 ml 40% kua nplaum tov yog muab tshuaj rau cov neeg mob. Tom qab ntawd, txhawm rau tswj cov piam thaj ntsiab lus saum toj no 1 g / l, 10% dextrose yog dripped.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj uas ua rau nce ntawm cov gliclazide
Cov tshuaj tua kab mob Miconazole yog contraindicated. Nce txoj kev pheej hmoo ntawm kev txhim kho hauv lub xeev hypoglycemic, txog li coma.
Kev siv ntawm Diabeton nrog rau qhov tsis yog-steroidal anti-inflammatory tshuaj Phenylbutazone yuav tsum ua tib zoo ua ke. Nrog kev ua haujlwm ntawm lub cev, nws ua kom qeeb qeeb ntawm kev tshem tawm cov tshuaj tawm hauv lub cev. Yog tias noj ntshav qab zib yog qhov tsim nyog thiab nws tsis tuaj yeem hloov nws nrog txhua yam, kev hloov kho ntawm gliclazide tshwm sim.
Ethyl cawv ntau ua rau lub xeev hypoglycemic thiab inhibits cov nyiaj them poob haujlwm, uas pab txhawb kev txhim kho kom tsis xeev tsis xeev. Vim li no, nws raug nquahu kom tsis suav nrog cawv thiab tshuaj uas muaj ethanol.
Tsis tas li ntawd, kev txhim kho ntawm lub xeev hypoglycemic nrog kev tswj tsis tau siv nrog ntshav qab zib ua rau:
- Bisoprolol;
- Fluconazole;
- Captopril;
- Ranitidine;
- Moclobemide;
- Sulfadimethoxine;
- Phenylbutazone;
- Metformin.
Daim ntawv teev npe tsuas yog muaj qee qhov piv txwv, lwm yam cuab yeej uas nyob rau hauv tib pab pawg raws li cov npe tau muaj tib yam nkaus.
Diabeton-txo cov tshuaj
Tsis txhob noj Danazole, li nws muaj cov kab mob ntshav qab zib. Yog tias qhov kev txais tos tsis tuaj yeem tshem tawm, kev kho ntawm gliclazide yog qhov tsim nyog rau lub sijhawm kho thiab hauv lub sijhawm tom qab nws.
Kev tswj kom zoo yuav tsum muaj kev sib xyaw nrog cov tshuaj tiv thaiv kev kho mob hauv cov tshuaj loj, vim tias lawv pab txo qis hormone tso tawm thiab nce ntxiv cov piam thaj. Kev xaiv ntawm cov koob tshuaj ntawm Diabeton MV yog nqa tawm ob qho tib si thaum kho thiab tom qab nws rho tawm.
Hauv kev kho mob nrog glucocorticosteroids, qhov concentration ntawm cov piam thaj nce nrog qhov txo qis hauv kev ua kom tau cov carbohydrate.
Kev tso quav β2-adrenergic agonists ua rau kom cov suab thaj ntau ntxiv. Yog tias tsim nyog, tus neeg mob pauv mus rau insulin.
Kev sib txuas tsis suav daws los dhau
Thaum kho nrog warfarin, Diabeton yuav ua rau kom nws cov nyhuv ntau dua. Qhov no yuav tsum tau coj mus rau hauv qhov kev suav nrog qhov sib xyaw ua ke no thiab kho cov koob tshuaj ntawm anticoagulant. Yuav tsum tau txhaj koob tshuaj rau lwm tus tom kawg.
Cov lus qhia tshwj xeeb
Kev ntshav siab
Nws raug nquahu kom noj cov mob ntshav qab zib MV tsuas yog rau cov neeg uas noj kom muaj txiaj ntsig thiab tsis tu ncua yam tsis noj mov tseem ceeb - noj tshais. Cov carbohydrates nyob rau hauv cov zaub mov noj yog qhov tseem ceeb heev, vim tias txoj kev pheej hmoo ntawm kev txhim kho lub xeev hypoglycemic nce kom meej nrog lawv siv tsis xwm yeem, nrog rau kev noj zaub mov kom yuag.
Cov tsos mob hypoglycemic tuaj yeem rov tshwm sim. Nrog cov tsos mob hnyav, txawm tias muaj kev txhim kho ib ntus tom qab cov khoom noj carbohydrate, yuav tsum muaj kev saib xyuas tshwj xeeb, qee zaum mus txog tsev kho mob.
Txhawm rau tiv thaiv qhov no los ntawm kev tshwm sim, koj yuav tsum ua tib zoo nrhiav txoj kev xaiv seb ntau npaum li cas rau tus mob ntshav qab zib.
Cov neeg mob uas ua rau muaj kev pheej hmoo siab mob ntshav qab zib:
- Kev tsis ua haujlwm thiab tsis muaj peev xwm ntawm tus neeg ua raws cov lus qhia ntawm kws kho mob.
- Khoom noj tsis zoo, hla zaub mov, tshaib plab.
- Tsis ua qhov tseem ceeb ntawm lub cev nrog qhov ntau ntawm cov carbohydrates noj.
- Tsis hlauv.
- Ib qho kev tshaj tawm ntawm gliclazide.
- Mob qog noj ntshav.
- Noj qee yam tshuaj.
Plaws thiab lub siab ua haujlwm
Cov khoom ntiag tug ntawm cov khoom hloov pauv vim yog muaj mob hepatic thiab lub raum tsis ua haujlwm. Lub xeev hypoglycemic tuaj yeem rub tau ntev, kev kho mob nrawm yog qhov tsim nyog.
Tus Neeg Mob Cov Ntaub Ntawv
Koj yuav tsum tau ua kev tawm dag zog tas li thiab saib xyuas koj cov piam thaj, lo rau cov zaub mov tshwj xeeb, thiab noj es tsis txhob ua txhaum. Tus neeg mob thiab nws cov neeg txheeb ze yuav tsum paub txog kev txo ntshav qis, nws cov paib thiab cov hau kev nres.
Kev tswj tsis tau glycemic
Thaum tus neeg mob ua npaws, kis kab mob, kis kev cuam tshuam loj rau kev kho mob, kev raug mob tau txais, kev tiv thaiv glycemic tsis muaj zog. Qee zaum nws yuav tsim nyog hloov mus rau tshuaj insulin nrog kev tshem tawm ntawm tus mob ntshav qab zib MV.
Cov tshuaj tiv thaiv kab mob thib ob yuav tshwm sim, uas tshwm sim thaum tus kab mob hloov zuj zus lossis thaum lub cev lub cev teb rau tshuaj tsawg dua. Feem ntau, nws txoj kev loj hlob tshwm sim tom qab kev kho mob ntev nrog kev kho qhov ncauj hypoglycemic. Txhawm rau kom paub meej txog kev ua haujlwm tiv thaiv kab mob thib ob, tus kws kho qhov muag endocrinologist txheeb xyuas qhov tseeb ntawm cov tshuaj uas raug xaiv thiab cov neeg mob ua raws kev noj haus uas tau teev tseg.
Muaj feem xyuam rau kev muaj peev xwm tsav tsheb thiab cov txheej txheem
Lub sijhawm ua haujlwm thaum tsav tsheb lossis ib txoj haujlwm twg xav tau lub teeb pom kev zoo sai dua, tshwj xeeb yuav tsum ua.
Cov npe ntawm Diabeton MV
Lub npe Kev Lag Luam | Glyclazide ntau npaum, mg | Nqe, tshiav |
Glyclazide CANON | 30 60 | 150 220 |
Glyclazide MV OZONE | 30 60 | 130 200 |
Glyclazide MV PHARMSTANDART | 60 | 215 |
Diabefarm MV | 30 | 145 |
Glidiab MV | 30 | 178 |
Glidiab | 80 | 140 |
Lawbalong | 30 60 | 130 270 |
Gliklada | 60 | 260 |
Dab tsi tuaj yeem hloov tau?
Mob ntshav qab zib MV tuaj yeem hloov nrog lwm cov tshuaj nrog tib yam tshuaj thiab cov khoom xyaw dhia. Tab sis muaj qhov xwm txheej zoo li kev nyab xeeb - cov khoom siv uas mus txog lub hom phiaj, i.e. lub peev xwm ntawm cov tshuaj yuav tsum yaim. Txog rau qee qhov tsis zoo, muaj tsawg, uas txhais tau tias kev kho mob yuav tsis muaj txiaj ntsig, vim tias raws li qhov tshwm sim, txoj kev muab tshuaj yuav tsis muaj tseeb. Qhov no yog vim qhov tsis zoo ntawm cov ntaub ntawv raw, ntu ntu, uas tsis pub cov tshuaj nquag tso tawm tag nrho.
Txhawm rau zam teeb meem, txhua yam kev hloov pauv yog ua kom zoo tshaj plaws tsuas yog tom qab sab laj nrog koj tus kws kho mob.
Maninil, Metformin lossis Diabeton - uas yog ib qho zoo dua?
Txhawm rau piv qhov twg zoo dua, nws tsim nyog txiav txim siab qhov tsis zoo ntawm cov tshuaj, vim tias lawv tag nrho cov tshuaj rau tib tus kabmob. Cov lus qhia txog cov tshuaj Diabeton MV tau muab rau saum toj no, yog li ntawd, Maninil thiab Metformin yuav raug txiav txim siab ntxiv.
Maninil | Metformin |
Kev txwv tom qab rov qab txhaws ntawm cov txiav thiab cov mob uas muaj malabsorption ntawm cov zaub mov, tseem muaj kab mob hauv plab. | Nws yog txwv tsis pub rau kev quav dej cawv ntev, lub plawv thiab lub ntsws ua tsis taus pa, tsis muaj ntshav, muaj kab mob kis. |
Muaj feem ntau ntau ntawm kev txuam nrog cov khoom nquag hauv lub cev hauv cov neeg mob uas lub raum tsis ua haujlwm. | Cov kev xav tsis zoo cuam tshuam rau kev tsim cov fibrin txhaws, uas txhais tau tias nce sij hawm los ntshav. Kev phais mob muaj feem ua rau muaj ntshav nce siab ntxiv. |
Qee lub sijhawm muaj qhov tsis pom thiab pom kev nyob. | Ib qho mob tshwm sim loj heev yog kev txhim kho ntawm cov kab mob lactic acidosis - kev sib txuam ntawm cov kab mob lactic acid nyob rau hauv cov ntaub so ntswg thiab ntshav, uas ua rau lub cev tsis nco qab. |
Feem ntau provokes cov tsos ntawm lub plab zom mov ntshawv siab. |
Maninil thiab Metformin koom nrog nyias pawg pharmacological, yog li txoj ntsiab cai ntawm kev ua yog txawv rau lawv. Thiab txhua tus nyias muaj nyias qhov zoo uas yuav tsim nyog rau qee pab pawg ntawm cov neeg mob.
Qhov zoo:
Maninil | Metformin |
Nws txhawb nqa cov haujlwm ntawm lub plawv, tsis ua rau tsis mob myocardial ischemia rau cov neeg mob uas muaj mob rau txoj hlab ntshav ntawm lub cev thiab arrhythmia nrog ischemia. | Muaj kev txhim kho glycemic tswj los ntawm kev nce qhov rhiab heev ntawm peripheral phiaj cov ntaub so ntswg rau insulin. |
Nws yog tshuaj rau qhov tsis muaj txiaj ntsig ntawm lwm yam sulfonylurea derivatives. | Piv nrog rau cov pab pawg ntawm sulfonylurea derivatives thiab insulin, hypoglycemia tsis txhim kho. |
Txuas lub sijhawm ntxiv rau qhov xav tau tshuaj insulin vim kev quav tshuaj yeeb ib puas. | Txo cov roj cholesterol. |
Txo lossis ruaj khov lub cev qhov hnyav. |
Los ntawm cov zaus ntawm kev tswj hwm: Diabeton MV noj ib hnub ib zaug, Metformin - 2-3 zaug, Maninil - 2-4 zaug.
Nqi hauv cov chaw muag tshuaj
Tus nqi ntawm Diabeton MV 60 mg sib txawv ntawm 260 rubles. mus txog 380 rub. rau ib pob ntawm 30 ntsiav tshuaj.
Kev Ntsuas Xyuas Mob Ntshav Qab Zib
Catherine. Tsis ntev los no, kws kho mob tau sau ntawv hais txog mob ntshav qab zib MV rau kuv, Kuv noj 30 mg nrog Metformin (2000 mg ib hnub). Qab zib poob qis los ntawm 8 mmol / L txog 5. Qhov tshwm sim yog txaus siab, tsis muaj kev phiv, ntshav qab zib heev.
Valentine Kuv tau haus Diabeton tau ib xyoos, kuv qab zib yog qhov qub. Kuv noj zaub mov, Kuv tabtom taug kev thaum yav tsaus ntuj. Nws yog qhov uas kuv tsis nco qab noj tom qab noj cov tshuaj, tshee tshee tshwm sim hauv lub cev, Kuv nkag siab tias nws yog ntshav qab zib. Kuv tau noj qab zib tom qab 10 feeb, Kuv hnov zoo. Tom qab qhov xwm txheej ntawd kuv noj tas li.