Tsuas yog tus kws kho mob koom nrog kev teem caij tshuaj tiv thaiv kab mob, kev xaiv ua rau muaj kev nyuaj vim muaj kev phiv thiab contraindications.
Cov piam thaj hauv cov tshuaj qis, xws li Metformin thiab Maninil, qhov sib txawv ntawm cov txheej txheem ntawm kev ua thiab lub zog ntawm cov nyhuv hypoglycemic.
Qhov no yog vim cov tshuaj sib txawv ntawm cov tshuaj, xav txog lawv cov yam ntxwv thiab qhov sib txawv.
Muaj pes tsawg leeg
Metformin yog cov tshuaj los ntawm ntau cov lej loj uas pab txo cov ntshav qabzib los ntawm kev nqus nws cov pa hauv lub siab.
Maninyl suav nrog cov tshuaj glibenclamide, sulfonylurea derivative ntawm lub cim thib ob nrog lub suab thaj txo cov nyhuv. Cov tshuaj yog tsim hauv cov ntsiav tshuaj nrog ntau koob tshuaj ntawm cov khoom xyaw.
Pharmacological kev txiav txim
Lub hauv paus ntsiab lus ntawm Metformin yog rau tshuaj tua kabmob gluconeogenesis. Cov tshuaj ua rau cov enzyme tshwj xeeb hauv lub siab uas txwv tsis pub cov piam thaj ntxiv mus rau hauv cov ntshav. Cov tshuaj txwv tsis pub hloov ua ke ntawm cov roj ntsha thiab txhawb lawv oxidation, inhibits qhov nqus ntawm cov suab thaj hauv cov hnyuv.
Piv nrog rau lwm cov kab mob ntshav qab zib tsawg, cov tshuaj muaj txiaj ntsig zoo tshaj plaws hauv kev tiv thaiv kev mob ntshav qab zib angiopathy. Nrog rau kev siv tshuaj, cov tshuaj txwv tsis pub rog, thiab thaum ua kom yuag, nws pab txo.
Metformin Cov ntsiav tshuaj
Cov tshuaj inhibits kev loj hlob ntawm insulin tsis kam thiab pab txhawb kev nkag mus ntawm cov piam thaj rau tib neeg cov ntaub so ntswg. Nrog rau cov tshuaj insulin tsis txaus nyob hauv cov ntshav, cov tshuaj yeeb yaj kiab tsis pom cov khoom hauv lub cev hypoglycemic.
Maninyl txhawb kev tsim tawm cov tshuaj insulin hauv cov txiav ua rau vim li ntawm cov kab xo potassium nyob hauv beta hlwb. Cov ntsiab lus ntawm cov poov tshuaj ions tau nce zuj zus, uas ua rau cov neeg nqus dej hiav txwv ua lub teeb liab kom coj tau cov kua dej tshiab.
Cov tshuaj muaj peev xwm nce cov lus teb hauv lub cev metabolism, txo qhov kev pheej hmoo ntawm kev mob hlwb thiab kev tuag. Lub tshuab ntawm kev ua tsis cuam tshuam nrog tus nqi ntawm cov piam thaj hauv cov ntshav, yog li cov tshuaj ua haujlwm txawm tias muaj kab mob normoglycemia.
Cov Khoom Qhia
Metformin tau raug muab tshuaj uas yog ib tug neeg mob ntshav qab zib ntshav qab zib hom 2 mob ntshav qab zib.
Hauv hom 1 mob ntshav qab zib, tshuaj tuaj yeem muab los kho ua kev tiv thaiv kab mob rau kev txhim kho cov ntshav qab zib mob ntsws.
Kev siv tshuaj hypoglycemic tuaj yeem siv rau polycystic ovary, yog tias muaj kev tiv thaiv hyperinsulinemia thiab ntshav qabzib.
Glibenclamide tsuas yog siv rau hom 2 mob ntshav qab zib mellitus, thaum siv cov khoom noj kom zoo thiab thauj khoom txaus nws tsis tuaj yeem ua kom txo qis ntshav qab zib.
Kuv puas tuaj yeem nqa nws ua ke?
Txhawm rau xav txog qhov ua tau ntawm kev sib txuam ntawm cov tshuaj, koj yuav tsum coj mus rau hauv tus account yam ntxwv ntawm lawv kev nkag thiab kev cuam tshuam ntawm cov tshuaj muaj yees.Cov suab thaj-txo cov teebmeem ntawm glibenclamide nyob ntawm qhov ntau npaum li cas: qhov loj dua nws yog, ntau dua cov nyhuv ntawm qhov txiav.
Thaum tsa los ntawm cov tshuaj nquag, cov tshuaj insulin ntxiv yuav pib tsim, yog li kev xaiv ntawm qhov xav tau ntawm Maninil yog txiav txim siab los ntawm ntshav qab zib.
Thaum sau ntawv noj tshuaj, tus kws kho mob yuav tsum muab lus qhia txog kev noj zaub mov kom zoo thiab coj mus rau hauv tus lej ntawm cov nyiaj carbohydrates hauv zaub mov. Thaum pib theem, kev kho pib nrog kev siv tshuaj noj qis kawg nkaus, thiab tom qab kev tswj hwm, cuam tshuam rau qhov uas mob ntshav qab zib.
Yog tias tsim nyog, nce cov tshuaj ntau ntxiv. Siv cov tshuaj 1-2 zaug hauv ib hnub, cov nyhuv ntawm cov tshuaj nquag yog tsawg kawg 12 teev.
Txhawm rau kom ua rau lub ntsej muag hypoglycemic thiab txo qis cov zaub mov carbohydrates hauv cov ntshav, ib txhij tswj hwm ntawm Maninil nrog Metformin yog ua tau.
Txoj kev sib xyaw ua ke ntawm cov tshuaj yog siv thaum nws tsis tuaj yeem ua kom tiav cov txiaj ntsig tsim nyog.
Ib qho tshuaj ntxiv ntawm cov tshuaj tiv thaiv kab mob siab yuav tsum tau coj mus rau hauv tus kws kho mob. Ua ke nrog lwm cov tshuaj, cov nyhuv ntawm glibenclamide ntawm lub cev ua kom zoo dua qub.
Qhov twg zoo dua?
Thaum sau tshuaj rau ib tus neeg sawv cev hypoglycemic, lawv tau kev coj ua los ntawm cov nyhuv xav kho, qhov kev ua haujlwm ntawm kev ua haujlwm ntawm cov nquag, tam sim no contraindications rau kev siv thiab phiv.
Metformin lossis Maninil
Ib qho tshwj xeeb ntawm Metformin yog tias qhov ua kom cov ntshav qog ntshav tsis zoo cuam tshuam rau lub cev tsis cuam tshuam nrog tus nqi ntawm cov tshuaj insulin. Lub hauv paus ntsiab lus ntawm cov tshuaj yog txhawm rau txhawm rau ua tiav kev qabzib.
Metformin yog ib qho ntawm ob peb yam tshuaj uas qhov kev pheej hmoo ntawm kev txhim kho hypoglycemia yog tsawg heev. Ntxiv nrog rau qhov pom ntawm lub plab hnyuv cuam tshuam, cov tshuaj tau siv tsis muaj kev phiv. Cov kab mob lactic acid tuaj yeem tshwm sim nrog kev noj ntau dhau thiab yog tias lub raum tsis ua haujlwm.
Cov tshuaj Maninil
Yog li no, nrog kev tsim cov peptide hormone los ntawm tus txiav, tab sis nrog insulin tsis kam, Metformin yog qhov zoo dua.
Qhov tsis zoo suav nrog qhov tseeb tias biguanide tsis muaj peev xwm txo cov piam thaj nrog insulin tsis txaus hauv lub cev. Lub sijhawm ntev siv cov tshuaj tiv thaiv kev nqus ntawm cov vitamin B12, uas thaum kawg yuav ua rau kev txhim kho ntawm myalgia thiab anemia.
Glibenclamide tshuaj tsuas yog rau hom mob ntshav qab zib hom 2, thaum cov nyhuv ntawm lwm cov ntshav qab zib tsawg tsis txaus.
Sulfonylurea derivative (glibenclamide) muaj ntau cov kev mob tshwm sim:
- yog tias qhov tshuaj qias tshaj li cov ntshav tau dhau mus lawm, kev muaj ntshav qab zib siab heev yuav tshwm sim;
- hnyav;
- mob tej pob txha
- mob taub hau
- nce rhiab heev rau lub teeb;
- npaws
- kev zom plab zom mov;
- mob nkees ntev;
- proteinuria (protein tshwm nyob hauv cov zis);
- mob cholestatic syndrome;
- kev tsis haum tshuaj;
- nquag tso zis.
Daim ntawv ntawm contraindications rau cov tshuaj yog xyaum ua tib yam, tsuas yog tias glibenclamide yog nruj me ntsis txwv tsis pub coj nrog insulin-mob ntshav qab zib.
Metformin, Maninil tsis tuaj yeem siv rau hauv rooj plaub:
- mob dias taub;
- cev xeeb tub
- kev tawm tsam;
- ua txhaum ntawm daim siab thiab lub raum;
- cov tsos ntawm ketoacidosis;
- kev tiv thaiv tsis haum.
Glibenclamide tuaj yeem siv nrog ceev faj hauv kev haus cawv, uas rau biguanide yog ib qho kev txwv tsis pub tshaj.
Ntxiv rau, Metformin raug tso tseg 2 hnub ua ntej thiab tom qab xoo hluav taws xob, yog tias muaj kev qhia txog kev sib piv ntawm iodinated.
Maninil lossis Amaryl
Amaryl yog hypoglycemic raws li sulfonylureas ntawm III tiamCov. Muaj cov tshuaj ua kom nquag plias - glimepiride. Lub hauv paus ntsiab lus ntawm kev nqis tes yog los txhawb kev tso tawm ntawm endogenous insulin los ntawm tus txiav ua kab mob.
Amaryl ntsiav tshuaj
Tsis zoo li Maninil, Amaryl muaj cov nyhuv ntxiv - cov tshuaj inhibits gluconeogenesis. Cov nyhuv hypoglycemic ntawm Amaril yog ntau tshaj tawm thiab yog tsawg kawg 24 teev.
Maninil thiab Amaril tsis tuaj yeem raug sau tseg rau hom insulin-tiv thaiv ntshav qab zib. Thaum xaiv cov koob tshuaj ntawm Amaril thiab kev kho mob tom qab, ntshav cov ntshav qab zib yuav tsum raug xav txog, vim tias muaj qhov ua tau ntawm kev tsim cov ntshav qog ntshav qab zib.
Cov kev xav tsis zoo los ntawm kev siv tshuaj thiab cov lus sib kis cov kev coj ua tsis txawv. Qhov kev zam tshwj xeeb tshaj yog qhov ua rau lub plab zom mov tsis txaus ntseeg hauv Amaril, uas cuam tshuam nrog cov txheej txheem ntawm kev noj cov gluconeogenesis los ntawm cov tshuaj.
Related videos
Tus txheej txheem ntawm kev ua, daim ntawv ntawm tso tawm thiab nuances ntawm kev siv Metformin hauv kev yees duab:
Maninil thiab Amaryl muaj cov nyhuv hypoglycemic zoo, tab sis muaj cov npe tseem ceeb ntawm cov kev mob tshwm sim. Yog hais tias ntxiv pancreatic stimulation tsis xav tau rau insulin ntau lawm,
Metformin muaj qhov ua tau zoo meej. Nws rau ntau dua txo qhov kev pheej hmoo ntawm atherosclerosis, tsis ua rau nce phaus thiab tiv thaiv kev txhim kho ntawm lub plawv. Phiv los ntawm lub plab zom mov los ntawm kev noj biguanide sai dhau.
