Qhov tsim los ntawm cov ntshav txhaws ib txwm muaj lub txim loj thiab yog qhov tsis txaus ntseeg nyob hauv tib neeg lub cev.
Tam sim no, muaj ntau qhov sib txuam ntawm cov tshuaj uas pab tiv thaiv lawv cov tsos.
Cov tshuaj no feem ntau siv los ntawm cov poj niam cev xeeb tub rau kev tiv thaiv, cov neeg mob uas muaj thrombosis rau kev kho, thiab lwm yam hauv tsab xov xwm no, ob yam tshuaj no, uas yog Fraxiparin thiab Kleksan, yuav raug kuaj hauv ntau yam.
Pharmacological kev txiav txim
Fraxiparin yog yeeb tshuaj uas zwm rau pab pawg ntawm cov tshuaj anticoagulants uas muaj cov nyhuv antithrombotic.
Nws txhim kho cov ntshav ncig thiab ua kom cov cholesterol. Cov tshuaj nquag ntawm Fraxiparin yog calcium nadroparin. Qhov no yog qhov nyhav tsis tshua muaj qhov hnyav heparin uas yog tsim los ntawm depolymerizing tsis tu ncua heparin.
Antithrombotic cov haujlwm yog ua tiav los ntawm kev ua kom cov fibrinolysis los ntawm txoj kev tso tawm cov ntaub so ntswg plasminogen activator los ntawm cov hlwb endothelial thiab ua kom cov nqaij mos ua rau lub zog cia.
Nadroparin muaj tsawg qhov cuam tshuam rau thawj qhov mob hemostasis. Nws muaj kev nce qib ntawm txoj kev sib txheeb ntawm txoj haujlwm los tiv thaiv IIa thiab anti-Xa. Nws muaj qhov ua haujlwm sai thiab ntev antithrombotic.
Cov tshuaj Clexane 40 mg
Clexane yog qhov tsis tshua muaj molecular hnyav heparin, nrog rau kev ua yeeb yam ncaj qha anticoagulantCov. Cov tshuaj tiv thaiv kev ua haujlwm ntawm cov tshuaj yog enoxaparin Na, uas yog hais txog cov tshuaj nyhav nyhav heparins.
Qhov kev txiav txim ntawm cov quav yog vim qhov ua kom muaj cov tshuaj antithrombin III, ua rau muaj kev cuam tshuam cov kev txwv thiab kev tsim cov kev ua ntawm yam IIa thiab X. Cov tshuaj muaj cov nyhuv antithrombotic ntev, uas tsis cuam tshuam qhov khi ntawm fibrinogen rau platelet receptors thiab platelet aggregation.
Kev ntsuas rau siv
Cov tshuaj Fraxiparin raug pom zoo rau kev siv rau hauv cov xwm txheej hauv qab no:
- kev tiv thaiv ntawm cov teeb meem thromboembolic tom qab kev khiav haujlwm;
- kev kho mob ntawm cov teeb meem thromboembolic;
- kev kho mob ntawm angina pectoris, as Well as myocardial infarction.
Cov tshuaj Clexane tau pom zoo siv rau:
- kev tiv thaiv ntawm thromboembolism thiab mob txhaws txha hnyav;
- kev kho mob ntawm txoj hlab ntshav nqus;
- kev kho mob ntawm angina pectoris, as Well as myocardial infarction.
Txoj kev ntawm daim ntawv thov
Cov tshuaj Fraxiparin siv tshwj rau subcutaneously thiab intravenously:
- kev phais dav davCov. Nws raug nquahu kom siv cov tshuaj no tsawg kawg xya hnub hauv ib koob tshuaj 0.3 millilitents. Thawj koob tau muab rau tus neeg mob li ob mus rau plaub teev ua ntej kev phais mob;
- Kev phais mob pob qij txhaCov. Thawj koob tshuaj Fraxiparin raug siv rau cov neeg mob kaum ob teev ua ntej kev phais mob, thiab tseem yog tom qab tib lub sijhawm ntawm lub sijhawm tom qab nws. Cov tshuaj no raug nquahu kom siv nyob hauv kaum hnub.
Cov tshuaj Clexane tsuas yog siv rau kev tswj hwm subcutaneous, thaum nws tsim nyog paub tias cov tshuaj no txwv tsis pub ua cov tshuaj intramuscularly:
- hauv plab ua haujlwmCov. Nws siv nyob rau hauv qhov ntau npaum ntawm 20-40 milliliters ib zaug ib hnub ib zaug. Thawj koob tshuaj ua ntej kev phais mob raug muab ob teev;
- thaum ua haujlwm orthopedicCov. Ib koob tshuaj 40 milligrams yog siv ib zaug ib hnub ib zaug. Thaum pib, cov tshuaj raug tswj kaum ob teev ua ntej kev phais mob. Nyob rau tib lub sijhawm, tseem muaj lwm txoj kev tswj hwm rau kev tswj hwm, thiab nws yog 30 milliliters ib hnub ob zaug, thiab thawj koob tshuaj yog muab 12-24 teev tom qab phais.
Lub chav kawm ntawm kev kho mob nrog cov cuab yeej no yog los ntawm ib lub lis piam txog 10 hnub, thaum nws tuaj yeem txuas ntxiv kom txog thaum qee lub sijhawm, thaum tseem muaj kev pheej hmoo ntawm thrombosis. Feem ntau ncua tsis pub ntau tshaj tsib lub lis piam.
Cov Yuav Tsum Muaj
Cov tshuaj Fraxiparin yuav tsum tsis txhob siv rau hauv cov xwm txheej zoo li no:
- yog tias koj fab rau cov tshuaj tsis haum;
- yog tias yav dhau los siv cov tshuaj no ua rau kev txhim kho thrombocytopenia;
- nrog rau kev pheej hmoo lossis los ntshav tam sim no;
- nrog exacerbation ntawm tus kab mob ntawm duodenum lossis mob rwj;
- nrog cerebrovascular hemorrhagic kev raug mob;
- nrog cov kab mob endocarditis nyob rau theem mob huam sai.
Clexane yuav tsum tsis txhob siv rau hauv cov xwm txheej zoo li no:
- nrog intolerance mus rau ib qho ntawm cov tshuaj ntawm cov tshuaj;
- nrog txoj kev pheej hmoo siab los ntshav;
- cov poj niam cev xeeb tub nrog lub plawv ua pa valve;
- thaum lub hnub nyoog tsawg dua 18 xyoo.
Nws tseem yog qhov yuav tsum tau coj Clexane nrog ceev faj nrog:
- ib qho kiav txhab;
- keeb kwm ntawm kev tsis ntev los no ischemic mob stroke;
- hemorrhagic lossis ntshav qab zib retinopathy;
- malignant arterial kub siab;
- nyuam qhuav yug los;
- hemostatic cuam tshuam;
- endocarditis;
- mob pericarditis;
- tsis hnov mob raum thiab hepatic muaj nuj nqi;
- txoj kev raug mob;
- txuam nrog cov tshuaj uas cuam tshuam hemostasis;
- kev siv ntawm cov khoom hluav taws xob rau kev tiv thaiv.
Sab sij huam
Thaum kho nrog Fraxiparin, cov kev mob tshwm sim hauv qab no tuaj yeem tshwm sim:
- kev tsis haum tshuaj;
- los ntshav
- nce qib ntawm daim siab enzymes;
- me me hematomas ntawm qhov chaw txhaj tshuaj;
- hnoos qeev hnyav ntawm thaj chaw txhaj tshuaj;
- thrombocytopenia;
- eosinophilia;
- hyperkalemia
Thaum kho nrog Clexane, cov kev mob tshwm sim hauv qab no:
- los ntshav
- hemorrhagic syndrome;
- kev tsim kho cov hemorrhage hauv qhov chaw retroperitoneal;
- kev tsim kho cov hemorrhage hauv cov kab noj hniav cranial;
- ua kom neeg tuag taus;
- kev txhim kho hematoma ntawm txha caj qaum;
- kev txhim kho cov hlab hlwb ua haujlwm;
- tuag tes tuag taw
- paresis;
- thrombocytopenia;
- kev tsis haum tshuaj ntawm qhov chaw txhaj tshuaj;
- nce qib ntawm kev hloov tsheb.
Nrog kev los ntshav, nws yog ib qho tsim nyog los nres kev siv Clexane.
Noj ntau dhau
Yog tias dhau ntawm kev noj tshuaj ntau dua ntawm Fraxiparin, kev tswj hwm ntawm kev txhaj tshuaj ntau ntxiv yuav ua rau los ntshav.
Hauv qhov no, kev siv yeeb tshuaj tom ntej yuav tsum tau hloov mus, tab sis qhov no tsuas yog siv rau kev tso ntshav tawm me ntsis.
Yog tias ib qho kev noj qab haus huv ntau tshwm sim tom qab noj, tom qab ntawd txawm tias qhov ntau ntawm cov tshuaj tsis tuaj yeem ua rau muaj mob hnyav, vim tias nws muaj qhov nqus qis heev.
Kev huam yuaj txhaj tshuaj Clexane ntau dhau los thaum txhaj tshuaj tuaj yeem ua rau cov ntshav muaj teeb meem. Thaum noj ntawm qhov ncauj, muaj cov teeb meem tsis zoo vim tias cov tshuaj tsis nqus tawm.
Xyuas
Hauv kev tshuaj xyuas ntawm Fraxiparin, qhov tseem siv tau thaum cev xeeb tub yog sau ua qhov ntxiv.Txawm li cas los xij, cov neeg mob zoo li no tau txiav txim siab los ntawm qhov tseeb tias kev txhaj tshuaj tshwm sim hauv lub plab.
Ib qho zoo dua tseem tseem sau tseg tias cov tshuaj tiv thaiv qhov tshwm sim ntawm cov ntshav txhaws, txhim kho kev ntshav, ua haujlwm sai txaus thiab siv tau yooj yim.
Ntawm cov minuses, ntau dhau lawm tus nqi raug sau tseg, hematomas tom qab txhaj tshuaj, muaj cov kev mob tshwm sim loj heev, tab sis tib lub sijhawm lawv tsis tshua muaj nqi. Hauv kev txheeb xyuas ntawm Clexane, nws yog qhov qhia tias nws pom zoo thaum lub sijhawm cev xeeb tub, thiab rau ntau qhov no yog qhov ntxiv. Kev ua tau zoo, kev siv tau yooj yim thiab siv tau yooj yim tau sau tseg.
Ntawm cov minuses, qhov feem ntau tshaj plaws yog tias kev txhaj tshuaj yuav tsum ua hauv lub plab, thiab feem ntau lawv tsis tshua zoo siab. Tsis tshua kim dhau kuj tseem sau tseg, thiab muaj cov neeg muaj kev cuam tshuam loj heev thiab contraindications.
Qhov twg zoo dua?
Kev txiav txim xyuas qhov twg yog qhov zoo dua, Fraxiparin lossis Clexane yog qhov nyuaj heev. Txhua tus neeg mob xav tau ib tus neeg mus kom ze thiab kev teem sij hawm siv cov tshuaj uas tsim nyog tshaj plaws.
Cov tshuaj Fraksiparin 0.3 ml
Fraxiparin muaj cov kev mob tshwm sim tsawg dua thiab cov lus qhia sib kis, thiab Clexane, muaj ntau yam ua rau muaj kev mob loj, nrog rau kev tuag.
Yog tias peb txiav txim siab nqe ntu, ces Fraxiparin yog me ntsis pheej yig dua. Txog ntawm qhov ua tau zoo ntawm kev kho mob, ob qho tshuaj yeeb tshuaj tau muaj pov thawj sib luag ntawm cov neeg mob.
Xaus
Ob leeg kev xeeb tub sab-tus kws kho mob txog tus mob thrombophilia thaum cev xeeb tub:
Thaum xaiv cov tshuaj twg los kho mob rau tus neeg mob, Fraxiparin lossis Clexane, tus kws kho mob yuav tsum ua ntej txhua yam tsom rau cov kev tiv thaiv kabmob uas lawv muaj. Nws raug nquahu, txawm hais tias muaj kev qhia tias ua rau nws tuaj yeem siv cov tshuaj hauv qab kev saib xyuas thiab nrog ceev faj, ua kev xaiv rau cov tshuaj uas tsis muaj kev sib kis.
