Thioctic acid yog lub ntuj tso tshuaj tiv thaiv kab mob thiab tiv thaiv kev tiv thaiv lub hlwb, pab txhawb lub cev kom yuag, txhim kho cov mob ntshav qab zib, cov neeg mob ntshav qab zib, txo cov kev pheej hmoo ntawm cov kab mob plawv thiab daws kev mob. Thiab cov no tsuas yog qee cov txiaj ntsig ntau ntawm cov kab mob antioxidant no. Lwm lub npe rau thioctic acid yog lipoic, lossis alpha-lipoic acid.
ATX
Hauv cov kab ke kev tiv thaiv-kho-tshuaj-tso tshuaj (ATX) nws muaj cov cai hauv qab no: A16AX01. Txoj cai no txhais tau tias cov tshuaj no cuam tshuam rau lub plab zom mov, cov metabolism. Cov tshuaj no yog siv los kho lub plab zom mov thiab nyob rau hauv qee yam kev mob plab zom mov.
Thioctic acid yog ib qho tshuaj ntuj ua los tiv thaiv thiab tua.
Tso cov ntawv thiab cov nyob ua ke
Alpha lipoic acid nyob rau hauv cov khw muag tshuaj muaj muag ntau hom: ntsiav tshuaj, mloog zoo, hmoov lossis kua. Qee cov tshuaj uas muaj lipoic acid, tuaj yeem yuav hauv chaw muag tshuaj:
- Thioctacid 600 T;
- Espaas lipon;
- Lipothioxone;
- Thioctic acid 600;
- Berlition.
Cov tshuaj sib xyaw cov tshuaj sib txawv. Piv txwv, ib qho kev daws teeb meem Tielept infusion muaj 12 mg ntawm thioctic acid hauv 1 ml, thiab cov neeg muaj mob hauv nws: meglumine, macrogol thiab povidone. Hauv qhov no, ua ntej noj cov tshuaj, koj yuav tsum paub tseeb tias tsis muaj kev nkag siab rau qee yam tshuaj tshwm sim los ua cov tshuaj. Nyeem cov lus qhia rau kev siv ua ntej siv cov tshuaj.
Pharmacological kev txiav txim
Alpha lipoic acid tuaj yeem tiv thaiv qee yam ntawm kev puas tsuaj ntawm tes hauv lub cev, rov qab qib ntawm cov vitamins (xws li, vitamin E thiab K), nws muaj cov pov thawj tias cov tshuaj no tuaj yeem txhim kho txoj haujlwm ntawm neurons hauv ntshav qab zib. Normalizes zog, carbohydrate thiab lipid metabolism, tswj cov roj metabolism hauv lub cev.
Nws muaj ntau cov txiaj ntsig zoo ntawm lub cev:
- Stimulates qib ib txwm ntawm cov tshuaj hormones tsim los ntawm cov thyroid caj pas. Lub cev no tsim cov tshuaj hormones uas tswj kev loj hlob, kev loj hlob thiab metabolism. Yog hais tias kev noj qab haus huv ntawm lub qog ua haujlwm tsis zoo, ces kev tsim cov tshuaj hormones tshwm sim tsis tuaj yeem tswj tau. Cov kua qaub no tuaj yeem ua kom rov qab sib npaug hauv kev tsim cov tshuaj hormones.
- Txhawb nqa cov leeg mob. Thioctic acid tiv thaiv lub paj hlwb.
- Txhawb nqa txoj haujlwm ua haujlwm kom tsis tu ncua ntawm cov hlab plawv, tiv thaiv kab mob plawv. Cov tshuaj txhim kho kom ua haujlwm ntawm cov hlwb thiab tiv thaiv lawv cov oxidation, txhawb nqa cov ntshav kom txaus, uas yog, nws muaj cov nyhuv cardioprotective, uas tuaj yeem pab tau rau lub siab.
- Tiv thaiv cov leeg kev noj qab haus huv thaum txav lub cev. Lipoic acid txo lipid peroxidation, uas ua rau lub cell puas tsuaj.
- Txhawb nqa ua haujlwm ntawm lub siab.
- Khaws lub hlwb kom noj qab haus huv thiab txhim kho kev nco.
- Tswjhwm cov tawv nqaij ib txwm muaj.
- Kev npleem poob qis rau kev laus.
- Tswj cov ntshav qabzib ib txwm.
- Tswj lub cev nyhav kom zoo thiab txhawb nqa kev poob phaus.
Cov Tshuaj Pharmacokinetics
Thaum noj ib zaug, nws nqus tawm ntawm cov khoom noj sai sai (zaub mov txo tus nqi nqus). Concentration ua ntau kawg tom qab 40-60 feeb. Muab faib rau hauv qhov ntim ntawm kwv yees li 450 ml / kg. Nws yog tawm los ntawm lub raum (los ntawm 80 txog 90%).
Kev ntsuas rau siv
Nws yog ntawv los ntawm kws kho mob yog tias muaj:
- hnyav hlau ntsev lom thiab lwm yam tshuaj lom;
- rau kev tiv thaiv lossis kho cov qhov txhab mob ntawm cov hlab ntshav txhaws ntshav uas yug lub plawv;
- nrog rau cov kab mob siab thiab tus mob ntshav qab zib neuropathy thiab ntshav qab zib.
Cov tshuaj yuav siv tau los kho kev quav cawv.
Cov Yuav Tsum Muaj
Nws yog kis nyob rau hauv cov neeg mob nyob rau hauv cov ntaub ntawv ntawm:
- ua kom lub cev tsis haum rau cov tshuaj nquag lossis cov koom haum pabcuam ntawm cov tshuaj;
- coj menyuam thiab lub sijhawm pub mis;
- yog lub hnub nyoog qis dua 18 xyoo.
Yuav ua li cas noj thioctic acid 600?
Thaum noj ntawm qhov ncauj, qhov kev xav thawj zaug yog 200 mg 3 zaug hauv ib hnub, tom qab ntawd lawv siv mus rau 600 mg 1 zaug nyob rau ib hnub. Qhov koob tshuaj rau kev saib xyuas yog 200-400 mg / hnub.
Noj cov tshuaj rau ntshav qab zib
Yog tias muaj kev cuam tshuam rau cov ntshav qab zib (mob ntshav qab zib polyneuropathy), cov tshuaj yuav muab rau hauv qhov nyiaj ntawm 300 mus rau 600 mg rau kev tswj hwm ntshav txhua hnub rau 2 txog 4 lub lis piam. Tom qab ntawd, kev tu xyuas kev kho mob tau siv: noj cov tshuaj hauv daim ntawv ntawm cov ntsiav tshuaj hauv ib qho ntawm 200-400 mg / hnub.
Thioctic acid nyob rau hauv kev tawm dag zog
Lipoic acid nce kev ua haujlwm ntawm cov piam thaj hauv kev siv cov hlwb thiab tswj nws cov ntshav ib txwm. Cov tshuaj no pab txhawb kev thauj cov amino acids thiab lwm yam khoom noj muaj roj ntsha los ntshav. Ua li no, nws pab ua kom cov nqaij ntshiv nqus tau ntau dua creatine muaj.
Ib qho tseem ceeb ntawm kev tawm dag zog rau lub cev yog kev koom tes ntawm cov kua qaub hauv cov metabolism hauv lub zog hauv cov roj ntsha hauv lub cev. Qhov no tuaj yeem muab qhov zoo rau cov neeg ncaws pob thiab cov neeg tawm dag zog uas xav ua kom lawv lub cev muaj peev xwm thiab kev ua kis las.
Tib neeg lub cev tuaj yeem coj los ua cov kua qaub no, thiab nws kuj tuaj yeem tau txais los ntawm qee cov zaub mov thiab zaub mov ntxiv.
Cov tshuaj no ua rau glycogen ntau ntxiv hauv cov leeg nqaij thiab tswj qhov hloov chaw ntawm cov as-ham uas tsim nyog rau kev loj hlob ntawm cov leeg.
Ua ntej suav nrog kev pabcuam thioctic acid ntxiv rau hauv koj cov zaub mov noj, sab laj nrog tus kws tshaj lij.
Sab sij huam
Thaum noj tshuaj uas muaj thioctic acid, cov kev mob tshwm sim hauv qab no tuaj yeem tshwm sim:
- gagging;
- zoo nkaus yog qhov tsis xis nyob los yog hlawv tom qab ntawm sternum;
- nce hws;
- nyob rau hauv rooj plaub uas cov kua qaub yog siv los ntawm kev tswj kav, pom qhov muag, qhov pom tshwm sim tuaj yeem tshwm sim;
- siab intracranial siab yog tias cov tshuaj tau noj sai heev;
- kuj, vim kev tswj hwm sai, cov teeb meem ua pa yuav raug saib xyuas;
- kev tawm tsam ua xua, tawv nqaij ua pob;
- qhov pib ntawm cov tsos mob ntawm cov qog ntshav qab zib (vim tias muaj cov kua nplaum zoo dua qub).
Cov lus qhia tshwj xeeb
Rau cov neeg mob kho nrog cov kua qaub no, muaj qee cov lus qhia tshwj xeeb.
Cawv tau zoo
Tsis sib xws. Cov neeg uas siv cov tshuaj nrog thioctic acid yuav tsum tsis txhob haus cov dej cawv.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Hauv kev tshawb fawb qhov twg qhov tshuaj tiv thaiv txaus thiab qhov tshwj xeeb yuav tsum tau ua, yuav tsum tau saib xyuas vim tias cov khoom no cuam tshuam rau kev muaj peev xwm koom nrog cov haujlwm zoo sib xws uas tuaj yeem ua rau txaus ntshai.
Siv thaum cev xeeb tub thiab lactation
Thaum lub caij cev xeeb tub, noj cov kua qaub no yog contraindicated, zoo li thaum lactation.
Thioctic acid tswj hwm rau 600 tus menyuam
Rau cov menyuam yaus thiab tub ntxhais hluas hnub nyoog qis dua 18 xyoo, lipoic acid yog contraindicated.
Siv rau lub sijhawm qub
Cov neeg uas muaj hnub nyoog tshaj li 75 xyoos yuav tsum tau xyuam xim tshwj xeeb thaum siv cov khoom no.
Noj ntau dhau
Cov tsos mob ntawm kev noj haus ntau dhau yog xeev siab, ntuav, mob taub hau. Thaum muaj mob hnyav, ua rau tsis nco qab, ua rau cov leeg tsis tuaj yeem ua rau qaug dab peg, ua rau lub cev tsis muaj kua qaub qis nrog cov kab mob lactic acidosis, poob qis hauv cov ntshav qab zib qis dua li ib txwm muaj, DIC, cov ntshav tsis zoo ua ke (coagulation tsis meej), PON mob siab, mob hlwb pob txha thiab tsis tuaj yeem. tom qab ntawm cov pob txha pob txha mos ua ub no.
Nyob rau hauv rooj plaub ntawm kev overdose, pom zoo pw hauv tsev kho mob.
Nyob rau hauv rooj plaub ntawm kev overdose, pom zoo pw hauv tsev kho mob.
Kev cuam tshuam nrog lwm yam tshuaj
Nws tsis tas yuav siv ua ke nrog cov hlau nplaum magnesium-, hlau- thiab calcium uas muaj cov tshuaj no. Kev sib xyaw ntawm thioctic acid nrog cisplatin txo cov nyhuv thib ob. Nws yog tsis yooj yim sua kom sib txuas nrog kev daws teeb meem ntawm qabzib, fructose, Wigner. Cov tshuaj ua kom cov ntshav txo qog ua kom zoo ntawm cov tshuaj (piv txwv li Insulin), cov tshuaj tiv thaiv ntawm glucocorticosteroids.
Ethanol txo cov kev ua haujlwm ntawm cov tshuaj no.
Analogs
Ntawm cov analogues, koj tuaj yeem nrhiav cov tshuaj hauv qab no:
- Berlition 300 (tso tawm daim ntawv: mloog zoo, ntsiav tshuaj);
- Oktolipen (ntsiav tshuaj, tshuaj);
- Kev Siv Yis Hnav (tsi ntsees rau iv kev tswj hwm);
- Thiogamma (ntsiav tshuaj, tshuaj).
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj muaj thioctic acid (hauv Latin - acidum thioctic) raug faib tawm los ntawm cov chaw muag tshuaj nrog cov tshuaj.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Koj tsis tuaj yeem yuav cov tshuaj muaj thioctic acid hauv khw muag tshuaj yam tsis muaj kws kho mob sau tseg.
Nqe ntawm Thioctic Acid 600
Piv txwv li, tus nqi ntawm Berlition 300 los ntawm 740 rubles rau 30 ntsiav tshuaj, 5 ampoules ntawm 12 ml concentrate yuav raug nqi los ntawm 580 rubles.
Thioctacid 600T, 5 ampoules ntawm 24 ml txhua - los ntawm 1580 rubles.
Tialepta, 30 ntsiav tshuaj - los ntawm 590 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj cia rau hauv qhov chaw qhuav, tsaus, nyob deb ntawm menyuam yaus, ntawm qhov kub tsawg dua + 25 ° C.
Hnub tas sij hawm
Lub neej txee yuav txawv nrog cov tshuaj sib txawv thiab nyob ntawm daim ntawv tso tawm. Piv txwv li, Tialepta hauv cov ntsiav tshuaj muaj lub neej txee ntawm 2 xyoo, nyob rau hauv daim ntawv ntawm kev daws - 3 xyoos.
Kev tshuaj xyuas txog Thioctic Acid 600
Cov kev tshuaj xyuas zoo feem ntau txog cov tshuaj; cov kws kho mob pom zoo rau lawv cov neeg mob. Cov neeg tau txais kev kho mob tsis muaj kev mob tshwm sim loj heev. Ntawm qhov tsis tooj, kev kho mob coj tau zoo.
Cov kws kho mob
Iskorostinskaya O. A., kws kho mob poj niam, PhD: "Cov tshuaj tau tshaj tawm cov khoom antioxidant, muaj cov txiaj ntsig zoo los ntawm kev siv hauv cov neeg mob ntshav qab zib. Txawm li cas los xij, tus nqi yuav tsum qis dua me ntsis."
Pirozhenko P. A., kws kho mob vascular, PhD: "Cov chav kawm ntawm kev kho mob nrog cov tshuaj no yuav tsum tau nqa tawm tsawg kawg ob zaug hauv ib xyoos rau cov neeg mob ntshav qab zib mellitus.
Cov neeg mob
Svetlana, 34 xyoo, Astrakhan: "Kuv tau siv cov tshuaj raws li kws kho mob tau qhia 1 ntsiav tshuaj ib hnub ib zaug rau 2 lub hlis. Muaj cov smack muaj zog ntawm cov tshuaj thiab saj tsis hnov zoo."
Denis, 42 xyoo, Irkutsk: "Kuv tau muaj 2 chav kawm ntawm kev kho mob. Tom qab qhov thawj chav kawm kuv tau pom kev nce qib: muaj lub zog muaj zog, tsis qab los noj mov, thiab txhim kho tawv nqaij."