Nws tsis yog ib txwm ua tau los tswj hom 2 mob ntshav qab zib mellitus tsuas yog nrog kev pab ntawm cov khoom noj uas tsis muaj carb thiab cov leeg ntim cov leeg. Thiab nws yog ib qho tsim nyog los tawm tsam hyperglycemia, vim hais tias kev kho mob tsis paub yuav ua rau muaj kev mob hnyav.
Ntawm qhov kev phom sij tshaj plaws yog cov teeb meem plawv. Diabetalong (Latin Diabetalong), cov tshuaj hypoglycemic nrog rau lub sijhawm ntev lossis hloov pauv, yuav pab txo qhov kev pheej hmoo ntawm kev tsim CVD.
Pharmacological tau
Cov tshuaj tiv thaiv kev puas tsuaj ntawm cov tshuaj yog vim muaj cov nquag compound gliclazide. Cov ntsiav tshuaj muaj 30 lossis 60 mg ntawm qhov tseem ceeb thiab qhov tshwj xeeb: calcium stearate, hypromellose, talc, lactose monohydrate, colloidal silicon dioxide.
Diabetalong yog cov tshuaj ntawm 2 tiam sulfonylurea chav kawm. Thaum nws nkag mus rau hauv cov hlab ntshav, gliclazide txhawb kev ua kom tiav ntawm cov tshuaj endogenous los ntawm β-hlwb ntawm cov txiav, ua kom nrawm rau kev siv cov kua nplaum (nrawm rau kev ua haujlwm ntawm cov nqaij glycogen synthase). Tsis pub dhau ob peb hnub txij li hnub pib, glycemic profile yog li qub. Lub sijhawm sib nrug ntawm kev noj zaub mov hauv cov hnyuv mus rau kev tsim cov tshuaj endogenous insulin raug txo qis, thiab cov glycemic ntsuas los ntawm cov zaub mov raug txo kom tsawg.
Nws yog qhov xav paub tias 2 xyoos tom qab noj cov tshuaj, qhov siab ntawm insulin tom qab thiab C-peptide yog tswj. Qhov cuam tshuam rau lub cev hauv Diabetalong yog qhov nyuaj:
- Regulates carbohydrate metabolism;
- Nws muaj cov txiaj ntsig ua haujlwm tiv thaiv kabmob;
- Stimulates insulin secretion;
- Nws muaj cov nyhuv hemovascular (suppresses platelet aggregation).
Thaum cov piam thaj nkag mus rau hauv cov ntshav, gliclazide ua kom sai rau cov kua dej. Nrog kev kho tas li, cov tshuaj ceeb toom:
Microvascular cov teeb meem - retinopathy (ib qho kev hloov ntawm txoj leeg ntshav ntawm retina) thiab nephropathy (mob raum ua haujlwm);- Cov teebmeem Macrovascular - cov hlab ntsha tawg, plawv nres.
Microvascular cov teeb meem - retinopathy (ib qho kev hloov ntawm txoj leeg ntshav ntawm retina) thiab nephropathy (mob raum ua haujlwm);Cov tshuaj Pharmacokinetic
Los ntawm lub plab, cov tshuaj yog nqus tag nrho. Cov ntsiab lus siab tshaj plaws hauv cov hlab ntsha tau mus txog tom qab 2-6 teev, thiab rau cov ntsiav tshuaj nrog MV - 6-12 teev.
Kev kho mob nyhuv ntev li 24 teev, cov ntshav protein glycazide khi rau 85-99%. Hauv lub siab, cov khoom siv roj ntsha tau hloov pauv mus rau hauv cov khoom noj tshuaj, ib qho ntawm lawv muaj qhov zoo ntawm microcirculation. Ib nrab-lub neej yog 8-12 teev, rau cov ntsiav tshuaj nrog MB - 12-16 teev. Cov tshuaj siv tshuaj tawm ntawm 65% nrog zis, los ntawm 12% nrog quav.
Leej twg thiaj pom cov tshuaj noj
Qhov laj thawj ntawm kev teem sij hawm ntawm Diabetalong yog hom 2 mob ntshav qab zib, ob qho tib si raws li kev kho mob monotherapy thiab nyob rau hauv kev sib xyaw nrog insulin los yog cov tshuaj tiv thaiv kab mob zoo sib xws.
Cov sib txuam thiab cov kev txwv
- Ntshav Qab Zib Hom 1;
- Kev ua haujlwm tsis zoo;
- Pathology ntawm lub siab;
- Kev mob raum tsis zoo;
- Ketoacidosis;
- Hypo- thiab hyperthyroidism;
- Mob ntshav qab zib lossis hyperosmolar coma;
- Cev xeeb tub thiab pub niam mis
- Kev raug mob hnyav thiab kub hnyiab.
Diabetalong yog contraindicated rau cov poj niam cev xeeb tub, yog tias nws tsis tuaj yeem tso tseg thaum pub niam mis, tus me nyuam raug hloov mus rau cov khoom noj khoom haus cuav.
Kev siv cov glycoside tsis pub thaum coj ua ke nrog miconazole.
Sab sij huam
Qhov tsis xav ua rau lub plab zom mov tuaj yeem ua rau mob plab tsis ua mob rau hauv txoj kev tawm tsam, xeev ntuav, mob plab. Los ntawm ib sab ntawm cov metabolism, hypoglycemia yog ua tau, rau cov kab mob circulatory - eosinophilia, cytopenia, ntshav liab. Ntawm ib feem ntawm daim tawv nqaij, kev fab tshuaj tiv thaiv thiab ua kom lub cev yuag tau. Los ntawm cov kev paub ntawm cov kabmob muaj cov saj tsis sib xws, mob taub hau, tsis sib koom ua ke, tsis muaj zog.
Cov tshuaj sib cuam tshuam
Kev ua haujlwm ntawm glycoside yog txhim kho los ntawm kev siv ua ke nrog anabolic steroids, ACE inhibitors, β-blockers, cimetidine, fluoxetine, salicylates, MAO inhibitors, Flucanazole, Pentoxifylline, Miconazole, Theophylline, Tetracycline.
Muaj peev xwm ntawm glycoside tsis muaj zog thaum siv nrog concitantly nrog barbiturates, glucocorticoids, sympathomimetics, saluretics, rifampicin, tshuaj txwv tsis pub muaj menyuam, estrogens.
Yuav thov li cas
Glycloside yuav tsum noj nrog kev noj mov. Cov ntsiav tshuaj tau nqos tag nrho, ntxuav nrog dej hauv chav tsev kub. Tus kws endocrinologist tau xaiv cov koob tshuaj thiab kev kho mob rau tus kheej, coj mus rau theem ntawm tus kabmob thiab qhov tshuaj tiv thaiv tus mob ntshav qab zib rau cov tshuaj. Txog cov tshuaj Diabetalong, cov lus qhia rau kev siv pom zoo kom pib ntawm 30 mg thiab ib qho kev kho ntxiv hauv cov lus qhia ntawm nce (yog tias tsim nyog).
Yuav kom ua tiav cov txiaj ntsig siab tshaj plaws, nws yog ib qho tseem ceeb kom ua raws li txoj cai yooj yim.
- Cov koob tshuaj txhua hnub tau noj ib zaug, qhov zoo tshaj plaws - thaum sawv ntxov;
- Qhov ntau npaum li cas ntawm cov tshuaj tuaj yeem hloov kho nyob hauv 30 -120 mg / hnub;
- Yog tias lub sijhawm ntawm kev nkag mus kawm tsis tiav, qhov kev hloov pauv yuav tsum tsis txhob suav ob zaug los ntawm lub sijhawm tom ntej;
- Thaum xam qhov ntau npaum li cas, tus kws kho mob yuav siv mus rau hauv tus lej nyeem ntawm lub ntsuas thiab HbAlc.
Nrog cov txiaj ntsig tsis txaus, qhov kev cai tau nce ntxiv (tom qab kev pom zoo nrog tus kws kho mob), tab sis tsis ntxov dua ib hlis tom qab txhaj tshuaj glycoside thawj zaug. Txhua 2 lub lis piam, nrog kev them nyiaj tsis tiav ntawm glycemia, koj tuaj yeem nce lub koob tshuaj.
Nws yog ib qho tseem ceeb xav txog tias 1 ntsiav tshuaj ntawm Diabetalong PV muaj 60 mg ntawm glyclazide, qhov no sib haum rau 2 ntsiav tshuaj ntawm Diabetalong MV 30 mg txhua.
Thaum hloov cov ntshav qab zib rau gliclazide los ntawm lwm cov tshuaj hypoglycemic, so tsis tsim nyog, tshwj tsis yog sulfonylurea derivatives. Thawj koob tshuaj hauv qhov teeb meem no yog tus qauv - 30 mg, yog tias tus kws kho mob endocrinologist tsis tau hais nws txoj cai.
Hauv txoj kev kho mob nyuaj, Diabetalong siv ua ke nrog ntau hom tshuaj insulin, biagudins, α-glucosidase inhibitors. Nrog kev ceev faj, cov tshuaj yog tawm rau cov neeg mob ntshav qab zib los ntawm kev mob ntshav qab zib (mob ntshav dej cawv, ua haujlwm lub cev lossis kis las, tshaib plab, muaj kev ntxhov siab tom qab). Hematopoietic kev ua haujlwm yog cuam tshuam nrog kev txhim kho kev mob ntshav tsis txaus, thrombocytopenia, leukopenia, granulocytopenia.
Kev tiv thaiv kev nyab xeeb
Txhawm rau kom tsis txhob mob ntshav qab zib, nws yog ib qho tseem ceeb rau lub sijhawm ntawm kev siv tshuaj rau kev noj zaub mov, kom tiv thaiv kev tawg loj hauv cov zaub mov, kom tshem tawm qhov ua kom muaj dej cawv kom tsawg. Kev tswj hwm khov kho ntawm β-blockers tuaj yeem cuam tshuam cov tsos mob ntawm kev mob ntshav qab zib.
Lub xeev hypoglycemic tuaj yeem lees paub los ntawm mob taub hau, ua kom sib haum sib cuam tshuam, tsis muaj kev tiv thaiv ntawm kev tshaib kev nqhis, kev nyuaj siab, tsaus muag, plooj tsis pom kev, tsis pom kev. Cov tshuaj tiv thaiv adrenergic kuj tseem ua kom pom tseeb: ntxhov siab, tawm hws, poob rau hauv cov ntshav siab, mob plawv, lub plawv tawg. Dyspeptic cuam tshuam, cuam tshuam nyob rau hauv cov lus sib dhos ntawm tso quav, thiab cov tawv nqaij tawv (ua pob, tsis xis nyob, erythema, urticaria, Quincke's edema) yog cov yam ntxwv.
Kev ua kom tiav zoo tuaj yeem ua tsis tau yog tias tsis muaj zaub mov carb qis. Vim tias muaj teeb meem tshwm sim tsis zoo, cov tsav tsheb yuav tsum noj cov tshuaj nrog ceev faj. Cov lus pom zoo ib yam rau cov neeg sawv cev ntawm kev ua haujlwm uas muaj feem cuam nrog kev hloov siab thiab kev ntsuas.
Pathologies ntawm lub siab thiab cov kua tsib ducts ua rau tus kab mob siab, ua kom muaj enzyme kev ua si.
Yog hais tias tus neeg raug tsim txom nco qab, nws yuav tsum noj khob noom, haus ib khob dej tshuaj yej lossis lwm yam uas muaj cov khoom noj carbohydrates. Tom qab mob zoo dua, tus kws kho mob endocrinologist xav tau kev sab laj los kho qhov tshuaj lossis hloov cov tshuaj.
Analogues ntawm cov tshuaj
Raws li cov nquag tivthaiv rau Diabetalong, cov tshuaj analogue yuav yog cov tshuaj Glidiab muaj nqis txog 140 rubles. Cov kws kho mob muab cov mob ntshav qab zib thiab cov tshuaj ntshav qab zib MV rau qhov siab tshaj ntawm tus nqi ntawm 286 txog 318 rubles. Ntawm kev npaj ua lus, Glyclada kuj tseem tuaj yeem pom zoo.
Kev npaj nrog cov txiaj ntsig hypoglycemic zoo xws li Amaril, Glimepiride, Glemaz, Glyurenorm yuav zoo heev rau kev sib xyaw. Lawv raug xaj rau kev tiv thaiv hypersensitivity lossis lwm yam contraindications rau glycoside.
Tso tawm daim ntawv, chaw cia khoom
Diabetalong ntsiav tshuaj ua los ntawm Synthesis OJSC thiab MS-Vita LLC yog tsim hauv cov hlwv tshuab. Cov hlwv tau tso rau hauv ib lub thawv ntawv cardboard.
Cov tshuaj no tuaj yeem khaws cia rau 3 xyoos nyob rau hauv chav tsev kub, tawm ntawm qhov ua tiav ntawm tshav ntuj ncaj qha thiab menyuam yaus. Hauv cov khw muag tshuaj, Diabetalong muaj tshuaj rau tus nqi ntawm 98-127 rubles. rau 60 ntsiav tshuaj ntawm 30 mg.
Kuaj Cov Ntshav Qab Zib
Tus kws kho mob ntshav qab zib uas tau ntsib ntau yam dhau los ntawm Diabetolong, hauv kev txheeb xyuas sau tseg nws qhov zoo:
- Maj mam txhim kho ntawm cov ntsuas glucometer;
- Zoo sib xyaw nrog lwm yam tshuaj;
- Nqis tus nqi ntawm cov tshuaj;
- Lub peev xwm yuag poob thaum lub sijhawm tshuaj.
Tsis yog txhua tus neeg txaus siab rau qhov xav tau tas li (txog 5 zaug hauv ib hnub) kev tswj hwm glycemic, tab sis dhau sijhawm nws cov kev ntsuas nws tswj tau khov kho thiab xav tau kev txhim kho tus kheej-tswj tau tsawg dua.
Feem ntau, Diabetalong yog ib qho tshuaj tiv thaiv kev tiv thaiv kev quav tshuaj uas ua kom lub cev glycemic zoo. Thaum siv kom raug, nws muaj peev xwm tiv thaiv kev mob plawv thiab lwm yam mob hnyav ntawm ntshav qab zib hom 2.
