Glucobai (cov lus sau rau cov tshuaj - Acarbose) yog tib lub qhov ncauj tshuaj tua kab mob uas tau qhia rau hom 1 thiab 2 ntshav qab zib. Vim li cas nws thiaj tsis pom muaj kev siv dav dav li, piv txwv li, Metformin, thiab vim li cas cov tshuaj thiaj li zoo rau cov neeg muaj kev noj qab haus huv, nrog rau cov neeg ncaws pob?
Ib yam li Metformin, Glucobai yuav raug hu kom yog tsis yog ib tus neeg sawv cev hypoglycemic, tab sis antihyperglycemic, vim nws txwv tsis pub muaj piam thaj sai sai hauv kev teb rau cov khoom noj uas muaj carbohydrates, tab sis tsis tswj hwm qib ntawm glycemia. Qhov thib ob ntawm ntshav qab zib, nws yog siv ntau dua, nrog kev ua haujlwm siab tshaj plaws, nws ua haujlwm ua ke nrog lwm tus kab mob ntshav qab zib.
Glucobay raug mechanism
Acarbose yog ib qho inhibitor ntawm amylases - ib pawg ntawm cov enzymes lub luag hauj lwm rau qhov tawg ntawm cov roj carbon ntau lub cev molecules rau hauv cov yooj yim, vim peb lub cev tsuas tuaj yeem nqus monosaccharides (qabzib, fructose, sucrose). Qhov txheej txheem no pib hauv lub qhov ncauj (nws muaj nws tus kheej amylase), tab sis cov txheej txheem tseem ceeb tshwm sim hauv cov hnyuv.
Glucobai, nkag mus rau hauv txoj hnyuv, txhawm rau qhov cuam tshuam ntawm cov carbohydrates mus rau hauv cov lwg me me uas yooj yim, yog li cov carbohydrates uas nkag mus rau hauv lub cev nrog zaub mov tsis tuaj yeem nqus tau.
Cov tshuaj ua haujlwm hauv zos, tshwj rau cov plab hnyuv lumen. Nws tsis nkag rau hauv cov ntshav thiab tsis cuam tshuam rau kev ua haujlwm ntawm cov nruab nrog cev thiab tshuab (nrog rau kev tsim cov tshuaj insulin, cov piam thaj hauv siab).
Cov tshuaj yog ib qho oligosaccharide - txoj kev kho cov khoom lag luam ntawm cov kab mob Actinoplanes utahensis. Nws cov haujlwm muaj xws li thaiv α-glucosidase, ib qho roj ntsha ntawm pancreatic enzyme uas zom cov carbohydrates ua tsis yooj yim rau cov molecules. Los ntawm inhibiting qhov kev nqus ntawm cov carbohydrates ua txoj, Acarbose pab tshem tawm cov piam thaj ntau dhau thiab ua rau glycemia li qub.
Txij li thaum cov tshuaj maj mam poob qis, nws ua haujlwm tsuas yog tom qab noj mov.
Thiab vim tias nws tsis txhawb lub hlwb responsible-hlwb lub luag haujlwm rau kev tsim khoom thiab kev zais ntawm cov tshuaj insulin endogenous, Glucobai tsis ua rau kev mob glycemic.
Leej twg yuav qhia rau cov tshuaj
Cov suab thaj txo qis peev xwm ntawm cov tshuaj no tsis zoo li los ntawm cov tshuaj hypoglycemic analogues, yog li ntawd, nws tsis yog qhov siv los kho nws li kev kho mob monotherapy. Ntau zaus nws tau txiav txim siab ua qhov kev hloov kho, tsis yog rau ob hom mob ntshav qab zib mellitus, tab sis kuj rau cov mob ntshav qab zib: kev yoo mov glycemia cuam tshuam, hloov pauv hauv qabzib kam.
Yuav noj li cas
Hauv cov khw muag tshuaj saw Acarbose, koj tuaj yeem nrhiav ob yam: nrog kev noj tshuaj ntawm 50 thiab 100 mg. Kev pib noj cov tshuaj Glucobay, raws li cov lus qhia rau kev siv, yog 50 mg / hnub. Hauv lub lis piam, nrog cov txiaj ntsig tsis txaus, koj tuaj yeem them ib feem kaum hauv kev nce ntxiv ntawm 50 mg, faib tawm txhua cov ntsiav tshuaj hauv ob peb koob tshuaj. Yog tias cov tshuaj tau zoo txaus los ntawm tus mob ntshav qab zib (thiab muaj txaus txaus xav tsis txog ntawm cov tshuaj), tom qab ntawd cov tshuaj yuav tuaj yeem hloov kho rau 3 r / hnub. 100 mg txhua qhov. Qhov siab tshaj plaws rau cov mob Glucobay yog 300 mg / hnub.
Lawv haus cov tshuaj ua ntej noj mov lossis hauv cov txheej txheem nws tus kheej, haus ib ntsiav tshuaj nrog dej. Qee zaum cov kws kho mob qhia kom zom cov ntsiav tshuaj nrog thawj cov zaub mov.
Lub luag haujlwm tseem ceeb yog kom xa cov tshuaj mus rau qhov lumen ntawm txoj hnyuv, yog li los ntawm lub sijhawm ntawm kev nqus ntawm cov carbohydrates, nws tau npaj siab ua haujlwm nrog lawv.
Yog hais tias cov ntawv qhia zaub mov hauv qee kis yog tsis muaj carbohydrate (qe, tsev cheese, ntses, nqaij tsis muaj mov ci thiab sab lauj kaub nrog cov hmoov txhuv nplej siab), koj tuaj yeem hla kev noj tshuaj. Acarbose tsis ua haujlwm nyob rau hauv qhov kev siv ntawm monosaccharides yooj yim - ntshiab qabzib, fructose.
Cov nyhuv antihyperglycemic ntawm Glucobay tsis muaj zog, yog li nws feem ntau yog kws kho ntxiv rau hauv kev kho mob nyuaj. Raws li twb tau hais tseg, cov tshuaj nws tus kheej tsis ua rau mob ntshav qab zib, tab sis nyob rau hauv txoj kev kho mob nyuaj nrog rau lwm cov tshuaj hypoglycemic, xws li cov kev rau txim tau. Lawv nres qhov kev tawm tsam tsis yog muaj suab thaj, zoo li ib txwm muaj xws li, - tus neeg raug tsim txom yuav tsum tau muab cov zom zom zom kom yooj yim, uas acarbose hnov mob.
Kev xaiv phiv
Txij li acarbose inhibits qhov nqus ntawm cov khoom noj carbohydrate, tom kawg tsub zuj zuj hauv txoj hnyuv thiab pib ua kom mob siab rau. Cov tsos mob ntawm kev kho kom haum yog pom nyob rau hauv daim ntawv ntawm nce roj tsim, rumbling, whistling, tsam plab, mob rau thaj chaw no, raws plab. Raws li qhov tshwm sim, cov ntshav qab zib yog tseem ntshai tawm hauv lub tsev, raws li kev tsis sib haum xeeb ntawm cov quav ua rau lub siab tsis ncaj.
Kev tsis xis nyob ua rau lub zog tom qab kev noj zaub mov ntau nyob hauv cov carbohydrates sai, hauv cov suab thaj, hauv cov hnyuv thiab txo qis yog qhov yooj yim nqus tau cov carbohydrates. Glucobai pabcuam yog ib hom ntawm cov kev ntsuas ntawm cov khoom noj tshaj (carbohydrates), teeb tsa nws txoj kev txwv rau hom kev noj zaub mov kom zoo. Kev tawm tsam ntawm txhua yam muaj sia yog ib tus neeg, tej zaum yuav tsis muaj qhov hloov pauv hauv plab yog tias koj tswj koj cov zaub mov thiab qhov hnyav.
Ntxiv rau α-glucosidase, cov tshuaj tiv thaiv kev ua haujlwm muaj peev xwm ntawm lactase, ib qho enzyme uas zom lactose (mis qab zib) 10%. Yog hais tias tus mob ntshav qab zib tau pom yav dhau los txo qis kev ua si ntawm qhov enzyme, tsis nkag rau cov khoom noj siv mis (tshwj xeeb yog qab zib thiab mis) yuav txhim kho cov nyhuv no. Cov khoom siv mis nyuj tuaj yeem yooj yim kom zom.
Qhov tseem ceeb tsis tshua muaj dyspeptic cuam tshuam yog tawv nqaij ua xua thiab o.
Zoo li cov tshuaj feem ntau hluavtaws, nws tuaj yeem ua pob khaus ntawm daim tawv nqaij, khaus, liab liab, qee kis - txawm Quincke's edema.
Cov tshuaj tiv thaiv tsis sib xws thiab cov qauv siv rau acarbose
Tsis txhob xaj tshuaj Glucobai:
- Cov neeg mob uas muaj mob rau lub siab;
- Nrog mob plab hlaub;
- Yog tias muaj mob hnyuv (ua mob lossis mob ntev);
- Cov neeg mob ntshav qab zib nrog hernia (inguinal, femoral, umbilical, epigastric);
- Cov poj niam cev xeeb tub thiab lactating;
- Nrog malabsorption syndrome;
- cov neeg mob uas mob raum tsis ntev.
Muaj ob peb qhov sib piv rau Glucobay: raws li cov tshuaj tiv thaiv (acarbose), nws tuaj yeem hloov los ntawm Alumina, thiab los ntawm kev siv tshuaj - los ntawm Voxide.
Glucobay rau poob phaus
Feem ntau ntawm cov pej xeem hauv ntiaj teb feem ntau tsis zoo siab nrog lawv qhov hnyav thiab daim duab. Puas yog nws tuaj yeem thaiv qhov kev nqus ntawm cov carbohydrates hauv cov tsis muaj ntshav qab zib yog tias kuv tau ua txhaum rau kev yoo mov? Cov neeg tawm dag lub cev raug qhia kom "faus cov ncuav qab zib lossis haus cov ntsiav tshuaj ntawm Glucobay." Nws nplov pancreatic amylases, ib pawg ntawm cov enzymes uas tawg polysaccharides rau hauv mono analogs. Txhua yam uas txoj hnyuv tsis tau nqus, nqus dej nws tus kheej dej, ua rau muaj mob plab zom mov.
Thiab tam sim no cov lus qhia meej: yog tias koj tsis tuaj yeem tsis lees paub koj tus kheej qab zib thiab khoom qab zib, noj ib lossis ob ntsiav tshuaj Acarbose (50-100 mg) ua ntej koob tom ntej ntawm carbohydrates. Yog tias koj xav tias koj ua haujlwm dhau lawm, koj tuaj yeem nqos lwm ntsiav tshuaj 50 mg. Mob plab zawv nrog xws li "kev noj zaub mov" tsim txom, tab sis nws tsis yog qhov tsis paub tab thaum poob phaus, piv txwv li, nrog orlistat.
Yog li nws puas tsim nyog nws "tau siv tshuaj lom neeg" yog tias koj tuaj yeem rov qab cov zaub mov qua ntxi tom qab noj mov ntau hnub so? Lub gag reflex yuav tsim nyob rau hauv ib hlis, thiab koj yuav rov tsim dua tshiab lub sijhawm twg los xij, txawm tias tsis muaj dej thiab ob tus ntiv tes. Nws yog qhov nyuaj thiab kim los kho cov pathologies, yog li nws yooj yim dua rau siv cov hnyuv hauv cov txheej txheem poob ceeb thawj.
Glucobay - txheeb xyuas cov ntshav qab zib
Yog li nws puas tsim nyog lossis tsis muaj nqis noj Glucobai? Cia peb pib nrog qhov tsis tau txais txiaj ntsig zoo:
- Cov tshuaj tsis yog nqus rau hauv cov ntshav thiab tsis muaj cov kabmob hauv lub cev;
- Nws tsis txhawb lub zog sib tov thiab kev zais cia ntawm nws tus kheej cov tshuaj insulin, yog li tsis muaj kev mob ntshav qab zib ntawm cov mob tshwm sim;
- Nws tau sim tsim tias kev siv lub sijhawm ntev ntawm kev siv acarbose txo qis txog qib "tsis zoo" cov roj (cholesterol) thiab tus nqi ntawm kev nce qib ntawm atherosclerosis hauv ntshav qab zib;
- Kev thaiv cov kev ua kom tsis muaj carbohydrate pab tswj qhov hnyav.
Muaj ob peb qhov tsis zoo: kev ua haujlwm tsis zoo thiab kev ua haujlwm tsis zoo ntawm kev kho mob monotherapy, nrog rau cov lus hais tawm kev cuam tshuam rau hauv daim ntawv ntawm mob tsis haum, uas ua rau pab tswj kev hnyav thiab noj zaub mov.
