Cov tshuaj tiv thaiv kabmob thiab tshuaj tiv thaiv kab mob nrog rau kev sib txuam ntawm ob qhov chaw nquag. Nws yog npaj rau kev kho mob ntawm cov neeg mob nrog kev qhia ua ke kev kho mob ntawm kev mob ntshav siab.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Ramipril + hydrochlorothiazide.
Lub npe txawv teb chaws uas tsis yog npe Hartil-D yog Ramipril + hydrochlorothiazide.
Ath
ATX Code C09BA05
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob hauv daim ntawv uas muaj cov xim daj ua daj. Daim ntawv sau yuav raug sau rau ib sab, nyob ntawm seb ntau npaum cas:
- 2.5 mg - rau ntawm ib sab thiab 12,5 mg - ntawm sab nraud, ntawm ob sab ntawm kev faib cov kev pheej hmoo;
- 5 mg rau ntawm ib sab thiab 25 mg ntawm sab nraud, hauv ob sab ntawm cov kev pheej hmoo.
Hauv ib pob ntawv cardboard tuaj yeem ua 2 lub hlwv ntawm 14 daim ib daig.
Cov tshuaj sib xyaw ntawm cov ntsiav tshuaj muaj 2 yam tshuaj:
- ramipril hauv qhov ntau npaum ntawm 2.5 lossis 5 mg;
- hydrochlorothiazide - 12.5 mg lossis 25 mg, ntsig txog.
Tsis tas li ntawd - cov tuab, cov xim xoos thiab lwm yam khoom zoo sib xws.
Pharmacological kev txiav txim
Ramipril yog cov tshuaj tiv thaiv tawg. Nws ua rau qeeb qis ntawm qhov kev txiav txim ntawm ACE inhibitor (exopeptidase), ua rau muaj kev cuam tshuam: kev tsis kam ntawm tag nrho cov hlab ntsha ntawm cov hlab ntsha thiab cov hlab ntsws capillaries ua me, qhov kev tsim tawm ntawm lub plawv thiab nce rau kev ntxhov siab nce ntxiv.
Tsis tas li ntawd, cov tshuaj nquag txhim kho ntshav txaus rau myocardium thiab txwv kev kis tus mob necrotization thaum lub plawv nres, txo qhov ntxim nyiam ntawm arrhythmias thiab qhov mob hnyav ntawm lub plawv tsis ua haujlwm.
Qhov tshuaj yeeb yam thib ob - hydrochlorothiazide - hais txog thiazides nrog cov yam ntxwv ntawm cov diuretic.
Hloov pauv cov sodium tshuav thiab txo cov lus teb rau norepinephrine thiab hom II angiotensin.
Nrog kev pab ntawm Hartil-D, lub siab nyob rau hauv lub portal txoj leeg yog txo.
Hauv cov neeg mob ntshav qab zib nrog nephropathy nrog kev pab ntawm cov tshuaj no, lub siab ntawm lub vev xaib leeg tau txo qis thiab kev txhim kho lub raum tsis ua haujlwm.
Cov tshuaj pib txog ib teev tom qab kev tswj hwm thiab kav ntev li ib hnub.
Cov Tshuaj Pharmacokinetics
Qhov nqus ntawm cov txheej txheem antihypertensive tshwm sim sai sai, thiab tom qab ib teev nws cov siab kawg tau mus txog (50-60%). Nws ua rau cov nquag plias thiab ua haujlwm hauv lub cev uas tau khi rau cov protein ntawm cov ntshav ntshav.
Lub diuretic yog nqus sai sai li ramipril, yog yooj yim faib thiab nthuav tawm 90% los ntawm lub raum hauv lawv cov ntawv qub.
Nws yog tawm hauv yuav luag sib npaug nrog cov zis thiab quav.
Thaum lub cev tsis ua haujlwm ntawm lub raum, lub siab ntawm ramiprilat (nquag metabolite) nce, thiab thaum muaj teeb meem daim siab, ramipril.
Kev ntsuas rau siv
Hartil D yog qhia txog ntshav siab, tab sis kuj tseem siv rau qee yam kab mob hauv lub plawv thiab lub raum.
Nws yog tawm hauv kev kho mob ntawm cov kab mob no:
- mob ntsws raum;
- arterial kub siab;
- mob ntshav qab zib lossis mob ntshav qab zib nephropathy;
- IHD los txo qis ntawm myocardial infarction lossis cerebral hemorrhage (mob hlab ntsha tawg).
Kev qhia siv yog kev xav tau kev sib koom ua ke hauv kev kho mob diuretics nrog cov tshuaj tiv thaiv kab mob siab.
Cov Yuav Tsum Muaj
Tsis txhob noj tshuaj yog hais tias:
- hyperreactions rau ib qho twg ntawm cov tshuaj lossis rau cov pawg ntawm sulfonamide pawg;
- qhov muaj ntawm edema ntawm qhov tob txheej ntawm daim tawv nqaij dermis thiab subcutaneous hauv qhov anamnesis;
- nqaim ntawm cov hlab ntsha hepatic nrog cov teeb meem ntshav khiav lossis nqaim ntawm cov hlab ntsha ntawm ib lub raum;
- cholestasis;
- arterial hypotension;
- nce mus txog 18 xyoo, vim tias tsis muaj cov ntaub ntawv ntawm cov nyhuv ntawm cov menyuam yaus lub cev;
- thaum adrenal cortex zais ntau dua aldosterone dua li qhov ib txwm xav tau;
- lub raum tsis ua hauj lwm.
Kev kho mob nrog poj niam tsis pom zoo thaum muaj menyuam hauv plab thiab thaum pub niam mis.
Nrog saib xyuas
Nrog qhov tseeb raug thiab nyob rau hauv kev saib xyuas ntawm tus kws kho mob, nws yog tsim rau thawj aldosteronism, tsis nkag siab lossis malabsorption ntawm qabzib lossis galactose, thaum mob hemodialysis,
Yuav Ua Li Cas Thiaj Siv Hartil D
Cov tshuaj yog muab los ntawm tus kws kho mob hauv txhua kis ntawm tus kheej.
Cov ntsiav tshuaj tau noj ntau zaus thaum sawv ntxov, yam tsis ntxo. Nyob rau tib lub sijhawm lawv haus dej ntau. Tsis txhob koom nrog kev ua noj.
Hartila-D ntsiav tshuaj feem ntau noj thaum sawv ntxov, tsis tas yuav zom.
Qhov siab tshaj plaws rau kev noj tshuaj txhua hnub yuav tsum tsis pub tshaj 10 mg.
Koob tshuaj rau ntau yam kab mob:
- Arterial hypertension - 2.5-5 mg ib hnub, nyob ntawm seb cov nyhuv tsim tawm.
- Mob plawv tsis ua hauj lwm ntev - 1.25-2.5 mg. Nrog rau qhov koob xav tau nce ntxiv ntawm qhov ntau tshaj ntawm 2.5 mg tuaj yeem faib ua 2 koob tshuaj.
- Tom qab myocardial infarction, kev sib xyaw ntawm ramipril + hydrochlorothiazide tau sau tseg tsis muaj ntxov dua peb hnub tom qab mob ceev. Tsuas tshuaj - 2.5 mg 2 zaug ib hnub. Muaj peev xwm nce ntxiv mus rau 5 mg 2 zaug hauv ib hnub.
- Txog kev tiv thaiv lub plawv nres, kev noj tshuaj thaum pib yog 2.5 mg, tom qab ntawd ob npaug tom qab 2 lub lis piam tswj hwm, thiab txawm tias 2 lub sijhawm tom qab 3 lub lis piam. Qhov siab kawg rau kev kho mob txhua hnub yog tsis ntau tshaj 10 mg.
Nrog ntshav qab zib
Thaum pib ntawm kev kho mob, ib nrab ntawm ib ntsiav tshuaj ntawm 2.5 mg yog noj 1 zaug hauv ib hnub. Hauv lub neej yav tom ntej, yog tias tsim nyog, nws muaj peev xwm nce qhov koob tshuaj ib hnub zuj zus mus rau 5 mg hauv ob koob faib.
Phiv Phim Hartila D
Feem ntau, qhov tsis xav tau ntawm kev ua ntawm cov tshuaj cuam tshuam rau kev ua haujlwm ntawm txoj hnyuv, hematopoiesis, lub hauv nruab nrab lub paj hlwb, tso zis thiab genitourinary system, ua pa ntawm lub cev, tawv nqaij, endocrine system, mob siab thiab cov kua tsib lub plab.
Kev kho mob txoj hnyuv
Xeev siab, ntuav, qhov ncauj qhuav, mob plab, mob quav.
Hematopoietic plab hnyuv siab raum
Los ntawm cov kabmob hemopoietic, kev hloov pauv ntawm qhov ntsuas ntawm qhov ntsuas tau yog:
- hemoglobin qib (poob, tshwm sim ntawm anemia);
- tus naj npawb ntawm cov qe ntshav liab, cov qe ntshav dawb thiab cov qe ntshav (txo qis);
- calcium qib (poob).
Nruab nrab hauv lub paj hlwb
Qhov pib ntawm kev tsis quav ntsej, nce tsaug zog, ntxhov siab, muaj suab nrov hauv pob ntseg, kiv taub hau thiab qaug zog tsis yog kav.
Los ntawm cov kab mob zis
Raug rau lub raum tuaj yeem ua rau mob oliguria,
Los ntawm lub tshuab ua pa
Ua tau bronchospasm, rhinitis, hnoos qhuav, txog siav.
Ntawm ib sab ntawm daim tawv nqaij
Cov pob xoo pob txha, ua paug tawm hws, nce tawm hws, hnov qhov sov ntawm qee qhov chaw ntawm cov tawv nqaij, alopecia.
Kev siv Hartila-D tuaj yeem ua rau tawm hws.
Los ntawm genitourinary system
Qoj tsawg libido, mob erectile kawg.
Los ntawm cov hlab plawv system
Tso rau hauv cov ntshav siab thaum sawv ntsug lossis sawv ntsug, lub siab hloov plawv, cuam tshuam ntawm Raynaud's mob.
Xws li qhov ua kom pom tseeb thiab muaj zog poob rau hauv cov ntshav siab, myocardial infarction lossis hlab ntsha tawg tuaj yeem tsim tawm.
Endocrine system
Muaj cov ntshav qabzib ntau ntxiv thiab uric acid.
Ntawm ib sab ntawm daim siab thiab cov hnyuv
Mob daj ntseg cholestatic, kab mob siab, ua kom daim siab, ua kom mob cholecystitis, mob siab necrosis.
Kev ua xua
Ua xua tuaj yeem tshwm sim hauv daim ntawv ntawm:
- urticaria;
- nce photosensitization;
- angioedema ntawm lub ntsej muag lossis larynx;
- o ntawm cov qij taws;
- exudative erythema;
- pom mob lwm yam, thiab lwm yam.
Kev siv Hartila-D yuav ua rau muaj kev tsis haum tshuaj nyob rau hauv daim ntawv ntawm urticaria.
Nrog rau kev ua txhaum fab hnyav, cov ntsiav tshuaj tau muab tso tseg.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Txij li thaum ua haujlwm nrog cov txheej txheem nyuaj yuav tsum tau mloog, tom qab ntawd, muab qee tus neeg cov tshuaj tiv thaiv tshuaj, ib qho yuav tsum tsis kam tsav lub tsheb thiab kev tsav tsheb tsawg kawg thaum pib kho.
Kev phiv tshuaj kuj tshwm sim rau hauv daim ntawv ntawm:
- hyperkalemia
- hyperazotemia;
- hypercreatininemia;
- nce residual nitrogen;
- hloov hauv lwm cov ntsuas ntsuas.
Lub cev cov leeg yuav teb rau cov tshuaj nrog cov leeg ib ce, mob caj dab thiab, tsis tshua muaj, tuag tes tuag taw.
Cov lus qhia tshwj xeeb
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj yog nruj me ntsis contraindicated nyob rau hauv lub thib ob thiab thib peb trimesters ntawm cev xeeb tub. Nyob rau lub sijhawm no, qhov muaj peev xwm siab tshaj plaws ntawm kev qaug tshuaj cuam tshuam rau ntawm lub cev. Vim tias tus yam ntxwv ntawm cov tshuaj hauv plab, tus me nyuam hauv plab yuav:
- lub raum tsis ua haujlwm;
- kev loj hlob tuaj;
- oligohydramnios;
- qeeb ossification ntawm lub pob txha taub hau.
Hartil-D yog nruj me ntsis nyob rau hauv kev txiav tawm hauv ob thiab thib peb lub cev xeeb tub.
Hauv lub sijhawm tom ntej, cov kab mob tshiab ntawm cov menyuam yug tshiab yuav tsim:
- tsis tshua muaj ntshav siab;
- hyperkalemia
- thrombocytopenia.
Txij li thaum muaj kev tso tawm cov tshuaj nrog niam mis, nws yog ib qho tsim nyog kom tsis txhob pub mis niam.
Teem caij Hartil D rau cov menyuam yaus
Cov kev tshawb fawb ntawm cov nyhuv ntawm cov tshuaj rau cov menyuam yaus tsis tau ua, vim li ntawd, txog thaum muaj hnub nyoog kaum yim nws tsis tau hais.
Siv rau lub sijhawm qub
Sau ntawv nrog kev ceev faj thiab nyob rau hauv cov koob tshuaj qis tshaj plaws.
Daim ntawv thov rau lub raum khiav tsis zoo
Hauv raum tsis ua haujlwm, cov koob tshuaj thiab chav kawm ntawm kev kho yuav tsum tau kho.
Qhov nyiaj pab ntau tshaj txhua hnub yuav tsum tsis pub tshaj 5 mg.
Hauv raum tsis ua haujlwm, qhov koob tshuaj Hartila-D thiab chav kawm ntawm kev kho yuav tsum tau kho.
Siv rau lub siab ua haujlwm tsis zoo
Qhov siab tshaj plaws niaj hnub noj tshuaj thaum muaj mob hauv lub siab ua haujlwm yuav tsum tsis pub ntau dua li 2.5 mg, thiab kev kho mob, vim tias qhov tshwm sim tsis zoo ntawm cov tshuaj, tau ua tsuas yog nyob hauv kev saib xyuas nruj ntawm tus kws kho mob.
Noj ntau dhau ntawm Hartil D
Nws zoo nkaus li:
- cramps
- tus ntse txo cov ntshav siab;
- kev tso zis;
- ob leeg hnyuv;
- lub siab tuaj yeem cuam tshuam kev cuam tshuam, thiab lwm yam.
Qhov ntsuas maj nrawm tshaj plaws yog siv cov roj carbon activated thiab sodium sulfate.
Kev kho ntxiv yog nyob ntawm cov tsos mob, nrog rau ncua sijhawm tshuaj thiab qhov ntau.
Kev cuam tshuam nrog lwm yam tshuaj
Nws tuaj yeem siv ua ke nrog thrombolytics, beta-blockers, acetylsalicylic acid.
Kev saib xyuas tshwj xeeb yog yuav tsum muaj nyob rau hauv kev sib koom tes tswj hwm ntawm cov tshuaj tau piav nrog:
- tshuaj kho mob;
- tshuaj loog;
- tricyclic cov tshuaj tiv thaiv kab mob;
- organic nitrates;
- vasodilators;
- tshuaj tiv thaiv kev puas tsuaj.
Tej zaum kev siv Hartila-D nrog acetylsalicylic acid.
Yog li, kev tswj hwm ib txhij nrog cov tshuaj diuretics provokes ib qho kev txo qis hauv cov ntshav siab.
Thaum siv nrog thiazide diuretics, nce ntxiv hauv ntshav calcium uas yog qhov ua tau.
Qee qhov tshuaj loog, organic nitrates (feem ntau feem ntau nitroglycerin), cov tshuaj tiv thaiv kev puas tsuaj, thiab tricyclic antidepressants muab cov nyhuv tib yam.
Cov tshuaj uas ua rau kom nce qib ntawm cov potassium nyob hauv cov ntshav (piv txwv li, potassium-sparing diuretics xws li Spironolactone, Triamteren, Renial, thiab lwm yam), cyclosporins tuaj yeem muab cov nyhuv ntawm hyperkalemia.
Cov tshuaj ntsev lithium muaj kuab lom ntau dua thaum noj nrog ACE cov tshuaj tiv thaiv kab mob, yog li ntawd, tsis txhob sib xyaw rau hauv ib koob.
Hypokalemia tuaj yeem tsim kho thaum noj nrog kev mob plawv glycosides thiab qee cov tshuaj tiv thaiv kev tiv thaiv.
Cov nyhuv antihypertensive ua rau tsis muaj zog nrog kev sib xyaw nrog sympathomimetics thiab kev siv mus ntev nrog cov tshuaj tsis-steroidal anti-inflammatory.
Cawv tau zoo
Nws yog tau los nce cov dej cawv, yog li kev sib koom tes tsis pom zoo.
Analogs
Muaj cov analogues nrog cov tib yam tshuaj thiab hauv tib lub tshuaj:
- Amprilan nl (Slovenia) - 30 ntsiav tshuaj;
- Ramazid n (Malta lossis Iceland) - 10, 14, 28, 30 thiab 100 daim.
Zoo sib xws cov tshuaj kuj tseem muaj, tab sis nrog lwm cov tshuaj nquag lossis tshuaj:
- Tritace ntxiv;
- Enalapril;
- Txhawb R;
- Prestarium thiab lwm yam
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Nws yog tso rau ntawm lub hwj tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Tsis muaj tshuaj yuav tsis kam xa.
Nqe rau Hartil D
Tus nqi ntawm cov ntim pob hauv qhov nyiaj ntawm 28 daim yog:
- los ntawm 455 rubles - 2.5 mg / 12.5 mg;
- los ntawm 590 rubles - 5 mg / 25 mg.
Cia rau cov neeg mob rau cov tshuaj
Nws raug nquahu kom khaws cov tshuaj ntawm qhov kub tsis dhau + 25º C hauv qhov chaw tsis muaj kev yoojyim rau menyuam yaus thiab tsiaj.
Nws raug nquahu kom khaws Hartil-D ntawm qhov kub tsis tshaj + 25º C.
Hnub tas sij hawm
Hnub tas sij hawm yog cim ntawm qhov ntim. Tsis txhob siv tom qab 3 xyoos txij li hnub tsim khoom lag luam.
Chaw tsim tshuaj paus
Lub teb chaws Yelemees tsim khoom ntawm lub tuam txhab "Alfamed Farbil Artsnaymittel GmbH" hauv nroog Gottingen.
Nws yog tsim nyob rau hauv lub Hoobkas ntawm Pharmaceutical tsob nroj EGIS CJSC hauv Hungary.
Kev tshuaj xyuas Hartil D
Kev kho plawv
Anton P., kws kho plawv, Tver
Kev xyaum tau qhia qhov ua tau zoo ntawm cov tshuaj hauv kev kho mob ntshav siab. Nws yog qhov yooj yim los siv thaum kev sib koom tes ntawm ACE inhibitors thiab diuretics yog qhia.
Elena A., kws kho plawv, Murmansk
Ib qho tshuaj tiv thaiv kab mob siab tiv thaiv hnyav, uas kuj tseem siv tau los tiv thaiv lub plawv nres. Qhov tsis zoo tsuas yog muaj ntau cov kev mob tshwm sim, qee zaum mob hnyav.
Cov neeg mob
Vasily, 56 xyoo, Vologda
Kuv tau kev mob siab los ntawm kev mob ntshav siab tau ntau xyoo. Kwv yees li 2 lub hlis dhau los Kuv tau txais tshuaj noj los ntawm cov tshuaj no los ntawm kws kho mob. Lub sijhawm thaum ntxov, kiv taub hau quaj thiab ib ce yaim. Nws hais rau tus kws kho mob thiab tom qab kev noj tshuaj hloov me ntsis, txhua yam poob rau hauv qhov chaw, thiab tam sim no kuv txoj kev noj qab haus huv yog qhov qub.
Ekaterina, hnub nyoog 45 xyoos, lub nroog Kostroma
Thaum tus kws kho mob tau sau cov tshuaj no, nws tau piav qhia tias txij li thaum muaj cov tshuaj sib txuam nrog kev kho mob, qhov no zoo li yuav tsim nyog nyob rau hauv rooj plaub no. Nws tau yooj yim los noj ib zaug ib hnub, thiab tsis tas yuav nco ntsoov seb puas yuav tsum noj ua ntej noj mov, thaum lossis tom qab. Yog tias koj tsis nco qab ua ntej noj tshais, ces koj tuaj yeem haus tom qab. Qhov tsuas yog tsis yooj yim - nyob rau hauv thawj ob peb hnub kuv yuav tsum tso kev tsav tsheb, vim tias kuv lub taub hau me ntsis kiv taub hau. Tab sis tom qab ntawd txhua yam ploj mus, thiab tam sim no kuv haus cov tshuaj no txhua hnub.
