Hauv 1 ml. Qhov tshuaj insulin Humulin muaj 100 IU ntawm tib neeg cov tshuaj insulin. Cov nquag ua haujlwm yog 30% solulin insulin thiab 70% insulin isofan.
Raws li cov khoom siv ntu siv:
- distilled metacresol,
- phenol
- sodium hydrogen phosphate heptahydrate,
- hydrochloric acid,
- tshuaj glycerol
- zinc oxide
- tshuaj sulfate,
- sodium hydroxide
- dej.
Daim ntawv tso tawm
Kev npaj koob tshuaj Humulin M3 insulin yog muaj nyob rau hauv daim ntawv ntawm kev ncua rau kev coj ua hauv dej hauv 10 ml fwj, ntxiv rau hauv 1.5 thiab 3 ml cartridges, ntim hauv thawv ntawm 5 daim. Daim cartridges yog tsim los siv hauv cov koob txhaj koob npe Humapen thiab BD-Cwj mem.
Cov tshuaj muaj cov nyhuv hypoglycemic.
Humulin M3 yog hais txog DNA siv tshuaj, cov tshuaj insulin yog ob zaug ua ntu raug ncua nrog qhov nruab nrab ntawm kev txiav txim.
Tom qab qhia cov tshuaj, ua haujlwm ntawm pharmacological tshwm sim tom qab 30-60 feeb. Qhov siab tshaj tawm tau ntev li ntawm 2 txog 12 teev, tag nrho lub sijhawm ntawm cov nyhuv yog 18-24 teev.
Humulin insulin kev ua si yuav txawv nyob ntawm qhov chaw tswj hwm tshuaj, qhov tseeb ntawm cov koob tshuaj xaiv, kev ua haujlwm ntawm tus neeg mob, kev noj haus thiab lwm yam.
Lub txiaj ntsig tseem ceeb ntawm Humulin M3 yog txuam nrog cov kev cai ntawm kev ua haujlwm ntawm kev ua kua nplaum. Cov tshuaj Insulin kuj tseem muaj cov nyhuv anabolic. Yuav luag txhua cov ntaub so ntswg (tshwj tsis yog lub hlwb) thiab cov leeg, insulin ua rau lub zog ntawm cov kua nplaum thiab amino acids, thiab tseem ua rau kev nrawm ntawm protein anabolism.
Cov tshuaj Insulin pab hloov cov piam thaj rau hauv glycogen, thiab kuj pab hloov cov piam thaj ntau dhau rau cov rog thiab inhibits gluconeogenesis.
Kev taw qhia rau siv thiab phiv
- Mob ntshav qab zib mellitus, nyob rau hauv uas kev kho tshuaj insulin yog kev pom zoo.
- Mob ntshav qab zib Gestational (ntshav qab zib ntawm cov poj niam cev xeeb tub).
Sab sij huam
- Tsim cov tshuaj hypoglycemia.
- Kev ua haujlwm tsis zoo.
Feem ntau thaum kho nrog insulin npaj, suav nrog Humulin M3, pom kev txhim kho hypoglycemia. Yog tias nws muaj daim ntawv foos hnyav heev, nws tuaj yeem ua rau lub siab tsis nco qab (poob siab thiab tsis nco qab) thiab txawm ua rau tus neeg mob tuag.
Hauv qee tus neeg mob, kev tawm tsam tuaj yeem tshwm sim, ua kom tawv nqaij ua pob khaus, o thiab ua pob liab liab rau ntawm qhov chaw txhaj tshuaj. Feem ntau, cov tsos mob no ploj ntawm lawv tus kheej hauv ob peb hnub lossis ntau lub lis piam tom qab pib kho.
Qee zaum qhov no tsis cuam tshuam nrog kev siv cov tshuaj nws tus kheej, tab sis yog los ntawm tus ntawm lwm yam los yog kev txhaj tshuaj tsis yog.
Muaj ua xua tshwm sim ntawm ib tug systemic. Nws tshwm sim ntau tsawg dua, tab sis muaj qhov hnyav dua. Nrog rau qhov kev cuam tshuam no, cov hauv qab no coj qhov chaw:
- ua pa nyuaj
- cov pob khaus dav dav;
- plawv dhia;
- poob hauv cov ntshav siab;
- txog siav
- tawm hws ntau dhau.
Feem ntau, cov ua xua tuaj yeem cuam tshuam tus neeg mob lub neej thiab yuav tsum tau txais kev kho mob xwm txheej ceev. Qee zaum cov insulin los hloov lossis desensitization yuav tsum.
Thaum siv tsiaj cov tshuaj insulin, kev tawm tsam, txo lub cev tsis zoo rau cov tshuaj, los yog lipodystrophy yuav loj hlob tuaj. Nrog rau kev teem sij hawm ntawm insulin Humulin M3, qhov tshwm sim ntawm cov txim zoo li no yuav luag tsis tau.
Cov lus qhia rau kev siv
Cov tshuaj insulin Hum3 M3 tsis raug tso cai muab tshuaj rau cov leeg ntshav.
Thaum sau ntawv ntawm cov tshuaj insulin, tsuas yog tus kws kho mob tuaj yeem xaiv qhov ntau thiab cov hom kev tswj hwm. Qhov no tau ua ib tus zuj zus rau txhua tus neeg mob, nyob ntawm qib glycemia hauv nws lub cev. Humulin M3 yog npaj rau kev tswj hwm subcutaneous, tab sis nws kuj tseem tuaj yeem raug tswj hwm intramuscularly, insulin tso cai qhov no. Nyob rau hauv txhua rooj plaub, tus mob ntshav qab zib yuav tsum paub yuav ua li cas txhaj tshuaj insulin.
Subcutaneously, cov tshuaj raug txhaj rau hauv plab, ncej puab, xub pwg lossis pob tw. Nyob rau tib qho chaw txhaj tshuaj tuaj yeem tsis pub tshaj ib hlis ib zaug. Thaum ua cov txheej txheem, nws yog ib qho tsim nyog yuav tsum siv cov khoom siv txhaj tshuaj kom raug, txhawm rau tiv thaiv kom tsis txhob tuaj yeem nkag rau hauv cov hlab ntshav, tsis txhob zaws rau qhov chaw txhaj tshuaj tom qab txhaj.
Humulin M3 yog ib qho npaj tau tov nrog Humulin NPH thiab Humulin tsis tu ncua. Qhov no ua rau nws tuaj yeem tsis npaj qhov kev daws teeb meem ua ntej coj mus rau tus neeg mob nws tus kheej.
Txhawm rau npaj cov tshuaj insulin rau kev txhaj tshuaj, Humulin M3 vial lossis NPH daim cartridge yuav tsum tau dov 10 zaug hauv koj txhais tes thiab, tig mus 180 degrees, maj mam co ntawm ib sab. Qhov no yuav tsum tau ua kom txog rau thaum qhov kev ncua ntawv zoo li mis los lossis kua huab, yam tsis haum kua txiv.
Nquag co insulin NPH tsis pom zoo, vim tias qhov no tuaj yeem ua rau pom kev ua npuas ncauj thiab cuam tshuam nrog kev siv pes tsawg. Tsis txhob siv cov tshuaj nrog sediment lossis plaub ya ri tuaj tom qab tov.
Kev tswj hwm insulin
Txhawm rau txhawm rau txhaj tshuaj, koj yuav tsum xub ua qee yam txheej txheem ua ntej. Ua ntej koj yuav tsum txiav txim siab qhov chaw txhaj tshuaj, ntxuav koj txhais tes kom zoo thiab so cov chaw no nrog daim ntaub ntub dej hauv cawv.
Tom qab ntawd, tshem lub hau tiv thaiv los ntawm rab koob koob txhaj tshuaj, txhim kho daim tawv nqaij (rub nws los yog nkag rau nws), ntxig rau rab koob thiab ua ib qho kev txhaj tshuaj. Tom qab ntawd lub koob yuav tsum tau muab tshem tawm thiab tom qab ob peb feeb, tsis tas yuav muab txhuam, nias qhov chaw txhaj tshuaj nrog lub tshuab ntswg. Tom qab ntawv, nrog kev pabcuam ntawm cov tiv thaiv sab nrauv lub hau, koj yuav tsum tau hle lub koob, tshem nws thiab muab lub hau rov qab rau ntawm xaum xaum xaum.
Koj siv tsis tau tib tug xaum xim ob zaug. Lub vial lossis daim cartridge siv tas kom txog thaum nws tso tag, ces muab pov tseg. Cov xwj syringe yog npaj rau cov tib neeg siv nkaus xwb.
Noj ntau dhau
Humulin M3 NPH, zoo ib yam li lwm yam tshuaj hauv pawg tshuaj no tsis txiav txim siab kev noj tshuaj ntau dhau, vim theem ntawm cov piam thaj hauv ntshav cov ntshav yog nyob ntawm kev sib cuam tshuam ntawm cov qog ntshav qabzib, insulin thiab lwm yam txheej txheem hauv lub cev. Txawm li cas los xij, kev tshaj tawm cov insulin tuaj yeem muaj kev cuam tshuam loj heev.
Kev mob ntshav qab zib yog nce los ntawm qhov tsis sib haum xeeb ntawm cov tshuaj insulin hauv plasma thiab cov nqi zog thiab zaub mov noj.
Cov tsos mob hauv qab no yog cov yam ntxwv ntawm tshwm sim hypoglycemia:
- nkees;
- tachycardia;
- ntuav
- tawm hws ntau dhau;
- pallor ntawm daim tawv nqaij;
- tshee
- mob taub hau
- tsis meej pem.
Muaj qee kis, piv txwv, nrog cov keeb kwm mob ntshav qab zib mellitus los yog nws saib xyuas ze, cov cim ntawm qhov pib ntawm lub qog ntshav yuav hloov. Kev tiv thaiv ntshav qab zib me me tuaj yeem tiv thaiv los ntawm kev noj ntshav qab zib lossis qab zib. Qee zaum koj yuav tau yoog qhov tshuaj insulin, rov qab xyuas cov zaub mov noj lossis hloov ua kom lub cev ua si.
Ntsig ntshav qab zib tsawg yog feem ntau kho los ntawm subcutaneous lossis intramuscular cov thawj coj ntawm glucagon, tom qab los ntawm kev noj zaub mov carbohydrates. Thaum muaj mob hnyav, muaj cov mob puas hlwb, ua kom yauv lossis tsis meej pem, ntxiv rau kev txhaj tshuaj glucagon, cov ntshav qabzib yuav tsum tau txhaj tshuaj kom tso ntshav khov.
Yav tom ntej, txhawm rau tiv thaiv kom txhob rov mob qog ntshav, tus neeg mob yuav tsum noj zaub mov ntau nyob rau hauv carbohydrates. Qhov teeb meem loj ntawm lub qog ntshav siab yuav tsum tau mus pw hauv tsev kho mob ceev.
Kev Sib Tham Yeeb Tshuaj NPH
Kev ua haujlwm ntawm Humulin M3 yog txhim kho los ntawm kev siv cov tshuaj tiv thaiv hypoglycemic qhov ncauj, ethanol, salicylic acid derivatives, monoamine oxidase inhibitors, sulfonamides, ACE inhibitors, angiotensin II receptor blockers, tsis xaiv-beta-blockers.
Cov tshuaj Glucocorticoid, cov tshuaj hormones kev loj hlob, qhov ncauj tawm tsam, danazole, cov thyroid hormones, thiazide diuretics, beta2-sympathomimetics ua rau txo qis hauv cov nyhuv hypulinlycemic ntawm insulin.
Ua kom muaj zog lossis, hloov pauv, tsis muaj zog ntawm kev vam khom rau cov tshuaj insulin muaj peev xwm ntawm lancreotide thiab lwm yam tshuaj ntxiv ntawm somatostatin.
Cov tsos mob ntawm cov qog ntshav qab zib yog lubricated thaum noj clonidine, reserpine thiab beta-blockers.
Cov nqe lus ntawm kev muag, khaws cia
Humulin M3 NPH muaj muag hauv khw muag tshuaj tsuas yog sau ntawv hauv lub hwj tshuaj.
Cov tshuaj yuav tsum khaws cia ntawm qhov kub ntawm 2 txog 8 degrees, tsis tuaj yeem ua kom zoo thiab tsis zoo rau tshav ntuj thiab kub.
Qhov qhib vial ntawm insulin NPH tuaj yeem khaws ntawm qhov kub ntawm 15 txog 25 degrees rau 28 hnub.
Ua raws li cov khoom tsim nyog yuav tsum tau kub, kev npaj NPH raug khaws cia rau 3 xyoos.
Cov lus qhia tshwj xeeb
Tsis tso cai rau kev kho mob lossis kev teem sijhawm noj tshuaj tsis haum (uas yog qhov tseeb tshwj xeeb rau cov neeg mob insulin) tuaj yeem ua rau mob ntshav qab zib ketoacidosis lossis hyperglycemia, uas ua rau muaj kev hem thawj rau tus neeg mob lub neej.
Qee tus neeg, thaum siv cov tshuaj insulin, cov tsos mob ntawm qhov pib hypoglycemia yuav txawv ntawm cov tsos mob ntawm tus tsiaj ntawm insulin, lossis yuav muaj tsos mob me me.
Tus neeg mob yuav tsum paub tias yog tias cov ntshav qabzib nyob hauv lub cev yog qhov ib txwm muaj (piv txwv li, nrog kev siv tshuaj insulin ntau ntxiv), tom qab ntawd cov tsos mob qhia tias yuav ua rau lub qog ntshav qab zib yuav ploj.
Cov kev qhia no tuaj yeem ua rau tsis muaj zog lossis txawv dua yog tias ib tug neeg noj beta-blockers lossis muaj mob ntshav qab zib ntev ntev, nrog rau muaj cov ntshav qab zib mob neuropathy.
Yog tias hyperglycemia, zoo li hypoglycemia tsis raug kho kom raws sijhawm, qhov no tuaj yeem ua rau tsis nco qab, tsis nco qab, thiab txawm tias tus neeg mob tuag.
Txoj kev hloov ntawm tus neeg mob mus rau lwm txoj kev npaj tshuaj insulin NPH los yog lawv cov hom yuav tsum tau ua tsuas yog nyob ntawm kev saib xyuas ntawm kws kho mob. Hloov cov tshuaj insulin rau cov tshuaj uas muaj cov kev ua txawv, cov txheej txheem tsim tawm (DNA recombinant, tsiaj), hom (npua, analog) yuav xav tau kev kub ntxhov lossis, ntawm qhov tsis sib xws, kev kho kom haum ntawm cov koob tshuaj uas tau hais tseg.
Nrog rau cov kab mob ntawm lub raum lossis mob siab, ua haujlwm tsis txaus ua haujlwm, kev ua haujlwm tsis txaus ntawm cov qog adrenal thiab cov thyroid caj pas, tus neeg mob xav tau cov tshuaj insulin yuav poob qis, thiab muaj kev ntxhov siab muaj zog thiab qee yam mob, ntawm qhov tsis sib xws, nce ntxiv.
Tus neeg mob yuav tsum nco ntsoov txog qhov muaj peev xwm ntawm kev txhim kho hypoglycemia thiab ntsuas tau zoo ntawm lub cev ntawm nws lub cev thaum tsav tsheb lossis xav tau kev ua haujlwm tsis zoo.
Analogs
- Monodar (K15; K30; K50);
- Novomix 30 Flekspen;
- Ryzodeg Flextach;
- Cov Kev Sib Tw Sib Ntsuas (25; 50).
- Gensulin M (10; 20; 30; 40; 50);
- Gensulin N;
- Tshuaj yaug NPH;
- Yawg Farmasulin H 30/70;
- Neej Neeg B;
- Vosulin 30/70;
- Vosulin N;
- Mikstard 30 NM;
- Protafan NM;
- Neeg lim hiam.
Cev xeeb tub thiab lactation
Yog tias tus poj niam cev xeeb tub muaj mob ntshav qab zib, yog li nws yog qhov tseem ceeb rau nws los tswj cov mob glycemia. Lub sijhawm no, cov tshuaj insulin feem ntau hloov pauv ntawm cov sijhawm sib txawv. Hauv thawj peb lub hlis, nws poob, thiab hauv zaum ob thiab thib peb nce, yog li tsim nyog kho qhov koob tshuaj yuav tsim nyog.
Tsis tas li, kev hloov pauv ntawm kev noj haus, kev noj haus thiab kev tawm dag zog lub cev thaum lub sijhawm lactation.
Yog tias qhov kev npaj tshuaj insulin no tsim nyog rau tus neeg mob ntshav qab zib mellitus, tom qab ntawd tshuaj xyuas txog Humulin M3, raws li txoj cai, yog qhov zoo. Raws li cov neeg mob, cov tshuaj no zoo heev thiab ua tau siv tsis muaj kev phiv.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias nws yog txwv tsis pub sau cov tshuaj insulin rau koj tus kheej, nrog rau hloov mus rau lwm tus.
Ib lub raj mis ntawm Humulin M3 nrog ib qhov ntim ntawm 10 ml nqi ntawm 500 txog 600 rubles, ib pob khoom ntawm tsib 3 ml cartridges nyob rau hauv thaj tsam ntawm 1000-1200 rubles.
