Hauv kev kho mob ntawm hom 2 mob ntshav qab zib mellitus, cov neeg sawv cev hypoglycemic tshwj xeeb los yog cov tshuaj insulin siv. Tus zoo hypoglycemic tus neeg sawv cev yog suav hais tias yog ntshav qab zib.
Cov tshuaj no zoo heev thiab ua rau pheej yig. Tus nqi ntawm cov tshuaj Diabeton 60 mg yog 250-300 rubles. Cov tshuaj kws kho mob tau muab xa tawm.
Thiab dab tsi yog cov khoom noj tsis haum ntawm Diabeton analogues? Hauv kev kho mob ntawm hom 2 mob ntshav qab zib mellitus, cov kab mob hypoglycemic tuaj yeem siv, uas muaj cov tshuaj xws li glimepiride, glibenclamide lossis glycidone.
Luv luv txog Diabeton thiab nws cov ntsiab cai ntawm kev ua
Diabeton yog ib txoj hauv kev kho mob ntshav qab zib, cov tshuaj tiv thaiv uas yog gliclazide. Kuv xav nco ntsoov tias cov khoom lag luam muaj nyob hauv qhov ntau npaum ntawm 60 mg thiab 30 mg. Ntxiv rau gliclazide, cov tshuaj sib xyaw ua ke suav nrog lactose, hypromellose, magnesium stearate, maltodextrin, silicon dioxide.
Yog li, dab tsi yog qhov nyhuv hypoglycemic ntawm cov tshuaj raws li? Gliclazide txo qis cov ntshav qab zib los ntawm kev ua kom muaj kua hauv cov ntshav ntawm beta pancreatic islets ntawm Langerhans. Hauv cov neeg mob ntshav qab zib, nrog rau kev siv tshuaj mob ntshav qab zib, thaum pib lub siab ntawm insulin secretion tau rov qab, thiab qhov ntxim nyiam ntawm kev muaj mob ntawm thrombosis tsawg dua.
Kev qhia rau kev siv ntshav qab zib yog mob thaum kev kho kev noj zaub mov tsis ua kom cov ntshav qabzib ntau. Tsis tas li, cov tshuaj noj yog siv thaum muaj qhov ntxim nyiam ntawm kev muaj kev cuam tshuam ntawm cov ntshav qab zib hom 2, tshwj xeeb tshaj yog tsis nco qab.
Cov lus qhia rau kev siv xeev tias Diabeton 60 mg lossis 30 mg yuav tsum noj nrog zaub mov. Ntxiv mus, qhov ntau zaus ntawm kev siv ntsiav tshuaj yog 1 zaug hauv ib hnub. Qhov pib txhaj tshuaj txhua hnub yog 30-120 mg. Thaum xaiv nws, hnub nyoog, tus yam ntxwv ntawm tus neeg mob thiab ntshav qab zib tau muab los xav.
Ntawm cov contraindications rau kev siv ntshav qab zib yog:
- Yam 1 ntshav qab zib.
- Lactation lub sijhawm.
- Ntshav qab zib poj koob yawm txwv los yog coma.
- Ntshav qab zib ketoacidosis.
- Hypersensitivity rau lub Cheebtsam ntawm cov tshuaj.
- Hepatic los yog lub raum tsis ua haujlwm.
- Kev siv quinolones lossis miconazole.
Ntawm cov kev mob tshwm sim ntawm cov tshuaj, kev ua txhaum nyob rau hauv kev ua haujlwm ntawm txoj hnyuv, kev ua tsis zoo ntawm daim tawv nqaij thiab cov nqaij mos tau tuaj yeem pom. Tsis tas li, qhov yuav ua rau muaj kev mob ntshav siab ntau, suav nrog ntshav liab, ntshav qab zib, granulocytopenia, tsis tuaj yeem txiav txim siab tau. Vim yog hloov ntshav hauv cov ntshav hauv lub ntsej muag, cuam tshuam hauv kev ua haujlwm ntawm cov plab hnyuv siab raum ntawm lub zeem muag yuav tshwm sim.
Cov kev mob tshwm sim feem ntau daws lawv tus kheej tam sim ntawd tom qab tsum tsis siv yeeb tshuaj.
Glimepiride
Cov tshuaj tiv thaiv zoo ntawm Diabeton yog cov tshuaj uas suav nrog glimepiride. Raws li cov tshuaj tiv thaiv ntawm Diabeton MV 30, koj tuaj yeem siv Glimepiride 2 mg n 10. Tus nqi tshuaj yog 150-200 rubles. Los ntawm txoj kev, Glimepiride 1 mg, 3 mg, 4 mg yog muag. Tag nrho lawv txhua qhov sib txawv ntawm cov tshuaj ntawm cov tshuaj nquag hauv cov ntsiav tshuaj.
Cov tshuaj no yog sulfonylurea derivative. Qhov nquag ua haujlwm ntawm cov tshuaj yog ua los ntawm kev txhawb cov tso tawm ntawm cov tshuaj insulin los ntawm pancreatic beta hlwb.
Glimepiride tuaj yeem siv kho mob ntshav qab zib hom 2 ntshav qab zib, yog tias cov piam thaj hauv ntshav tsis tuaj yeem kho tshwj xeeb los ntawm kev noj zaub mov noj thiab ua haujlwm lub cev.
Yuav ua li cas noj cov tshuaj no ntawm Diabeton MV? Cov lus qhia rau kev siv hais tias kev muab tshuaj yuav tsum yog tus kws kho mob xaiv. Hauv qhov no, tus kws kho mob yuav tsum coj mus rau hauv theem ntawm cov piam thaj hauv cov ntshav thiab zis.
Raws li txoj cai, thawj zaug tshuaj ntawm glimepiride yog 1 mg. Yog tias qhov koob tshuaj tsawg kawg nkaus tsis pab ua kom cov ntshav qabzib nyob hauv cov ntshav, tom qab cov tshuaj txhua hnub nce mus rau 2, 3 lossis 4 mg, feem. Tab sis peb yuav tsum nco ntsoov tias qhov koob tshuaj tau nce zuj zus ntawm ntu li 1-2 lub lis piam. Qhov siab tshaj plaws niaj hnub noj tshuaj yog 6 mg.
Tau kawg, Glimepiride, zoo li ib tus neeg sawv cev hypoglycemic, muaj ib tug xov tooj ntawm contraindications rau kev siv. Ntawm lawv yog:
- Ntshav qab zib Insulin-yam mob ntshav qab zib (hom 1).
- Ntshav qab zib ketoacidosis.
- Ntshav qab zib poj koob yawm txwv los yog coma.
- Kev ua haujlwm tsis zoo hauv lub siab.
- Malfunctions nyob rau hauv ob lub raum, nyob rau hauv kev raum tsis ua hauj lwm.
- Kev tsis haum tshuaj rau cov feem ntawm cov tshuaj. Ntxiv mus, koj tsis tuaj yeem noj glimepiride txawm hais tias ib tus neeg muaj kev tsis txaus ntseeg rau lwm cov kev sib txuas lus ntawm sulfonylurea.
Thaum kho, koj yuav tsum nruj noj zaub mov. Tab sis peb yuav tsum nco ntsoov tias, tsis muaj ib yam dab tsi koj tuaj yeem txo qhov kom muaj calorie kom tsawg. Txwv tsis pub, lub ntsej muag hypoglycemic kuj yuav tshwm sim. Tsis tas li, thaum kho nws yog txwv tsis pub haus cawv.
Qhov tshwm sim ntawm glimepiride:
- Kev ua kom tsis haum xeeb hauv kev ua haujlwm ntawm cov hlab plawv thiab hematopoietic. Lawv tshwm sim hauv daim ntawv ntawm qhov txo qis ntshav siab, thrombocytopenia, granulocytopenia, leukopenia, agranulocytosis, pancytopenia, erythropenia, ntshav liab.
- Kev ua haujlwm tsis zoo ntawm cov leeg hlwb thiab cov khoom hauv lub cev - kiv taub hau, mob taub hau, thim rov qab ua rau pom qhov tseeb.
- Xeev siab, ntuav, mob plab, zoo nkaus li hnyav nyob hauv thaj chaw epigastric, raws plab, mob cholestasis kom txhob mob heev.
- Qog taub hau ntshav qab zib.
- Kev Hyponatremia.
- Kev ua xua tsis haum.
- Ua tsis taus pa.
- Kab mob siab, nce kev ua si ntawm hepatic transaminases.
- Kev Lom Zem.
Thaum muaj kev phiv loj heev, cov tshuaj tau raug muab tso tseg, thiab lwm tus neeg sawv cev hypoglycemic yog xaiv.
Glibenclamide rau ntshav qab zib
Yog tias Tus Mob Ntshav Qab Zib MV 30 tsis haum, tom qab ntawd koj tuaj yeem yuav lub cuab yeej xws li Glibenclamide. Cov tshuaj yog nrov heev ntawm cov neeg mob ntshav qab zib, vim nws txoj kev ua tau zoo thiab ua siab ntev. Tus nqi ntawm Glibenclamide 5 mg n 100 tsuas yog 100-120 rubles.
Qhov hloov ntshav qab zib no muaj cov tshuaj glibenclamide uas nquag ua haujlwm, thiab cov khoom siv pabcuam - lactose monohydrate, cov hmoov txhuv nplej siab, povidone, E124, magnesium stearate.
Glibenclamide stimulates pancreatic beta hlwb, uas yog nrog los txhawb nqa thiab nce tso tawm cov tshuaj insulin endogenous. Cov tshuaj muaj txiaj ntsig zoo nyob rau hauv muaj qhov txiav txim siab ntawm txoj kev ua haujlwm muaj peev xwm ua haujlwm beta hlwb uas tsim cov tshuaj insulin endogenous. Cov tshuaj nquag ntawm Glibenclamide pab txo cov platelet aggregation.
Cov neeg tsim khoom lag luam qhia hauv cov lus qhia tias cov tshuaj no yuav tsum tau siv rau kev kho mob ntshav qab zib hom 2 thaum kev noj zaub mov noj thiab lwm yam kev kho mob tsis pab ua kom cov ntshav piam thaj tseem ceeb.
Thawj koob tshuaj glibenclamide yog 2.5-5 mg. Hauv qhov xwm txheej no, tus neeg mob yuav tsum tau soj ntsuam tas li qib ntawm glycemia. Yog tias qhov tsawg kawg koob tshuaj hypoglycemic nyhuv tsis tau hais, yog li kev noj tshuaj txhua hnub yog tsa.
Yog tias tsim nyog, glibenclamide ua ke nrog lwm tus neeg sawv cev hypoglycemic. Hauv qhov no, feem ntau ntau npaum kev txo thiab raug xaiv hauv txoj hauv kev zoo li txo qhov pheej hmoo ntawm kev txhim kho hypoglycemic coma.
Cov kev txwv tsis pub siv rau hauv cov tshuaj:
- Kev tsis haum tshuaj rau cov feem ntawm cov tshuaj. Nws tseem tseem tsis pom zoo kom noj cov tshuaj rau cov neeg mob ntshav qab zib uas yav dhau los muaj qhov tsis haum qhov tsis haum rau lwm tus sulfonylurea derivatives.
- Yam 1 ntshav qab zib.
- Ntshav qab zib poj koob yawm txwv los yog coma.
- Ua tiav nyob rau hauv daim siab.
- Lub raum tsis ua haujlwm thiab lwm yam kev ua haujlwm ntawm lub raum.
- Lub sijhawm ntawm cev xeeb tub thiab lactation.
- Ntshav qab zib lwj vim kev phais mob.
Nws yog tsim nyog kom nco ntsoov tias qhov ua kom cov ntshav qog ntawm Glibenclamide zoo dua yog tias ib tug neeg siv sulfonamides, tshuaj pleev xim, coumarin derivatives, heparin. Cov khoom qab zib qis tseem ua kom muaj zog ntxiv thaum ua ke nrog MAO inhibitors, cov tshuaj tiv thaiv hypocholesterolemic, qee qhov tshuaj tua kab mob thiab barbiturates.
Tab sis ib qho kev txo qis hauv hypoglycemic zog tuaj yeem tshwm sim yog tias Glibenclamide ua ke nrog cov tshuaj tua kab mob ntawm pawg rifamycin lossis thiazide diuretics.
Kev phiv los ntawm cov tshuaj:
- Kev ntshav siab.
- Lub plab zom mov tsis zoo. Qhia raws li qhov tsis txaus siab, qhov zoo li lub ntsej muag hauv xim hlau hauv lub qhov ncauj, ntuav, raws plab, mob plab, kub siab.
- Kev ua xua tsis haum.
- Cholestasis.
- Lub siab ua haujlwm tsis zoo.
- Malfunctions ntawm hematopoietic system.
- Ua txhaum ntawm rhiab heev.
Tsis tas li, cov lus qhia rau kev siv hais tias glibenclamide tuaj yeem ua rau kev txhim kho ntawm photosensitivity.
Glurenorm ua qhov hloov pauv
Tus mob ntshav qab zib tuaj yeem hloov nrog lub twj xws li Glyrenorm. Tus neeg sawv cev hypoglycemic no tsis muaj kev ua tau zoo. Tus nqi ntawm Glurenorm 30 mg n 60 yog kwv yees li 500-620 rubles.
Cov tshuaj tiv thaiv tsis ua haujlwm ntawm cov tshuaj yog glycidone. Rau cov hom phiaj pabcuam, lactose, pob kws hmoov txhuv nplej siab, magnesium stearate ntxiv rau cov ntsiav tshuaj. Lub hauv paus ntawm Glurenorm kev ua raws li yog dab tsi?
Glycvidone (cov tshuaj ua kom muaj zog) txhawb cov kev tawm tsam ntawm cov tshuaj insulin endogenous los ntawm cov qe hlwb ntawm cov txiav. Ntawd yog, txoj ntsiab cai ntawm kev ua ntawm cov tshuaj yog zoo li ntau cov neeg sawv cev hypoglycemic.
Nrog kev pab los ntawm Glyurenorm, nws muaj peev xwm kho hom 2 ntshav qab zib mellitus, thaum kev noj zaub mov zoo thiab kev ua si lub cev tsis pab tswj cov ntshav khov hauv cov ntshav. Qee zaum cov tshuaj no tau siv ua ke nrog lwm cov tshuaj hypoglycemic.
Yuav noj tshuaj li cas? Cov lus qhia rau kev siv hais tias thawj koob yuav tsum tsis pub tshaj 15 mg. Koj yuav tsum noj ib ntsiav tshuaj nrog zaub mov noj. Nrog rau qhov tsis muaj txiaj ntsig ntawm kev kho cov tshuaj, cov tshuaj ntau dua maj mam nce. Tab sis peb yuav tsum nco ntsoov tias qhov siab tshaj plaws niaj hnub noj yog 120 mg. Nws tsis yooj yim sua kom hla txoj kab hluav taws xob no.
Contraindications rau siv:
- Ntshav qab zib hom insulin.
- Precomatose lossis coma.
- Mob ntshav qab zib ua los ntawm acidosis lossis ketosis.
- Kev txiav tawv nqaij.
- Lub sijhawm ua ntej kev phais mob.
- Kev tsis sib haum xeeb hauv daim siab.
- Hepatic porphyria.
- Kev tsis haum tshuaj rau cov feem ntawm cov tshuaj.
Ntawm cov kev mob tshwm sim ntawm Glenrenorm, agranulocytosis, leukopenia, thrombocytopenia, hypoglycemia tuaj yeem sib txawv. Tsis tas li, ib qho tsis tuaj yeem tshem tawm txoj kev muaj peev xwm nkees nkees, kiv taub hau, mob taub hau, mob plab, kev nyob tsis haum, ua xua, cholestasis.
Nws tseem raug tshaj tawm tias noj Glurenorm tuaj yeem ua rau txoj kev loj hlob ntawm angina pectoris, lub plawv tsis ua haujlwm, thiab txo ntshav siab. Thaum pib ntawm txoj kev kho mob, kev ntxhov siab hauv kev ua haujlwm ntawm txoj hnyuv yog ua tau, tshwm sim hauv daim ntawv ntuav, cem quav, thiab lub qhov ncauj qhuav. Daim vis dis aus hauv tsab xov xwm no yuav tham txog Tus Mob Ntshav Qab Zib.
