Gliformin yog qhov tshuaj hypoglycemic rau kev siv hauv lub qhov ncauj, nws zwm rau pab pawg ntawm biguanides. Cov tshuaj inhibits glycogenesis nyob rau hauv daim siab, txo qis kev nqus, nce qhov rhiab heev ntawm cov ntaub so ntswg rau cov tshuaj insulin, thiab ua rau kev siv peripheral qab zib.
Nyob rau tib lub sijhawm, cov tshuaj tsis tuaj yeem cuam tshuam rau cov kua dej los tsim cov qis, txo qis cov triglycerides, cov lipoproteins uas tsis muaj ntau, thiab cov ntsuas qhov hnyav. Tsis tas li ntawd, vim qhov kev txwv ntawm plasminogen inhibitor los ntawm hom nqaij, fibrinolytic nyhuv tshwm sim.
Rau ib pob ntawm cov tshuaj hauv ib zaj duab xis txheej, tus neeg mob yuav tsum muab kwv yees li 300 rubles, Gliformin ntsiav tshuaj nrog rau kev faib nyiaj yuav raug nqi kwv yees li 150 rubles. Kev txheeb xyuas txog cov tshuaj feem ntau yog qhov zoo, nws tsis tshua muaj kev xav tsis zoo rau lub cev.
Pharmacological kev txiav txim
Cov tshuaj tuaj yeem raug yuav hauv cov tshuaj sib txawv: 250, 500, 850 thiab 1000 mg. Cov tshuaj tiv thaiv tseem ceeb ntawm cov tshuaj yog metformin. Qhov ua tau zoo ntawm kev kho yog tiav thaum cov mob ntshav qab zib txuas ntxiv tsim nws cov tshuaj insulin lossis cov tshuaj hormone no ntxiv rau tswj hwm.
Cov muaj tswv yim:
- sorbitol;
- qos yaj ywm hmoov txhuv nplej siab;
- stearic acid;
- povidone.
Cov tshuaj tau nrawm nrawm los ntawm cov kab mob hauv lub plab ntawm cov plab hnyuv, nws qhov siab tshaj plaws tau pom ob teev tom qab noj cov ntsiav tshuaj. Lub zom zaws ua kom haum ntawm metformin hydrochloride yuav muaj txog li 50-60%, cov tshuaj tsis nkag mus rau hauv kev sib chwv nrog cov protein. Los ntawm lub cev, cov tshuaj tau khiav tawm hauv nws cov qauv qub.
Mob ntshav qab zib, Gliformin noj tsuas yog hais ntawm ncauj xwb. Koj yuav tsum paub tias lub tshuab ntawm nws cov kev nqis tes ua tseem tsis tau raug ua tiav kev kawm. Tom qab nkag mus rau hauv cov hlab ntsha, cov tshuaj nquag ntawm cov tshuaj koom nrog cov txheej txheem xws li:
- kev ua kom nrawm ntawm kev tawg ntawm carbohydrates;
- txo cov piam thaj hauv cov piam thaj uas los ntawm cov hnyuv;
- kev tsuj tawm ntawm kev tsim cov kua nplaum nyob hauv lub siab.
Kev siv cov tshuaj rau cov ntshav qab zib thiab ntau theem ntawm cov rog tiv kev ua kom poob hauv lub cev qhov hnyav thiab qab los noj mov. Cov lus qhia rau kev siv cov tshuaj hais tias lub tshuaj ua kom nquag plias ntawm cov tshuaj metformin pab yaj cov ntshav txhaws, tiv thaiv platelet adhesion.
Cov lus qhia rau kev siv ntsiav tshuaj
Kev qhia rau kev siv tshuaj yog hom 2 mob ntshav qab zib mellitus, thaum kev noj zaub mov nruj thiab sulfonylurea pawg tshuaj tsis muaj cov nyhuv xav tau. Glyformin tseem ua rau kev mob ntshav qab zib hom 1 ua qhov txuas rau cov tshuaj insulin.
Lub sijhawm kho mob, kev ua haujlwm ntawm lub raum yuav tsum tau saib xyuas, tsawg kawg txhua 6 lub hlis nws raug nquahu kom ntsuas los txiav txim lactate hauv cov ntshav ntshav.
Cov ntsiav tshuaj tuaj yeem ua qaug dej tau thaum noj mov lossis tom qab noj mov, qhov ntau npaum li cas yuav tsum tau sau tseg ib leeg los ntawm tus kws kho mob uas koom nrog, suav rau hauv cov txiaj ntsig ntawm kev kuaj ntshav qab zib:
- thaum pib ntawm txoj kev kho, qhov tshuaj tsis ntau tshaj 1 gram ib hnub;
- tom qab 15 hnub, cov nyiaj ntawm cov nyiaj tau nce.
Tus txheej txheem kev saib xyuas cov tshuaj yuav tsum tsis pub ntau tshaj 2 gram nyob rau ib hnub, nws yuav tsum tau faib tusyees tshaj ob peb koob tshuaj. Cov neeg mob ntshav qab zib ntawm lub hnub nyoog qib siab ib hnub raug pom zoo kom noj ntau tshaj 1 gram ntawm cov tshuaj.
Yog tias tus kws kho mob tau sau ntawv rau Gliformin rau cov ntshav qab zib, tus neeg mob yuav tsum paub tias cov ntsiav tshuaj tuaj yeem ua rau ntau yam kev tsis zoo ntawm lub cev. Ntawm ib feem ntawm cov kab mob endocrine, kev mob ntshav qab zib ntshav nce siab, nyob rau ntawm ib feem ntawm cov ntshav ncig ua haujlwm yog muaj peev xwm ua tau, nyob rau ntawm ib feem ntawm cov metabolism hauv cov vitamins tsis muaj peev xwm tshwm sim. Lub cev qee zaum ua rau cov tshuaj tsis haum nrog kev fab tshuaj:
- urticaria;
- khaus tawv nqaij;
- ua pob.
Los ntawm cov plab hnyuv ntawm lub plab zom mov muaj qhov ua txhaum ntawm lub qab los noj mov, raws plab, ntuav, ib qho xim hlau hauv qhov ncauj.
Yog tias muaj qhov tsis zoo tshwm sim, nws yog qhov qhia kom tsis kam kho nrog Gliformin, sab laj nrog kws kho mob.
Cov tshuaj Glyformin (nws cov lus qhia muaj kev ywj pheej muaj nyob hauv Is Taws Nem) tuaj yeem siv rau kev ua kom lub raum tsis ua haujlwm, tab sis tsuas yog thaum tsis muaj kev cia siab rau qhov nce ntawm lactic acidosis. Hauv qhov no, lub raum kev ua haujlwm yog ib txwm kuaj xyuas (tsawg kawg ib zaug txhua 3-6 lub hlis), thaum kev tshem tawm creatinine txo qis mus rau theem ntawm 45 ml / min, kev kho mob tam sim ntawd nres.
Yog tias lub raum kev ua haujlwm raug txo qis hauv kev mob ntshav qab zib siab, kev noj cov tshuaj metformin yuav tsum tau kho.
Cov tshuaj tiv thaiv tsis zoo, sib cuam tshuam nrog tshuaj
Gliformin yuav tsum tsis txhob siv rau ketoacidosis, mob siab rau mob ntshav qab zib, mob ntshav qab zib tsis ua hauj lwm, mob plawv, mob ntsws tsis ua hauj lwm, thaum cev xeeb tub, pub niam mis, myocardial infarction, kev paub ntau dhau los ntawm cov tshuaj ntawm cov tshuaj.
Tshaj tawm kom zoo zoo kho cov tshuaj rau cov kab mob ntawm kev kis tus kab mob sib kis, ua ntej kev kho mob hnyav.
Qhov ua tau zoo ntawm cov tshuaj tuaj yeem txo qis nrog kev kho mob sib luag:
- glucocorticosteroid tshuaj;
- cov thyroid hormones;
- tshuaj kho mob;
- nicotinic acid;
- thaum noj qhov ncauj tawm.
Yog tias cov tshuaj metformin siv ua ke nrog insulin, sulfonylurea derivatives, tshuaj tsis muaj tshuaj tiv thaiv kab mob, thiab beta-blockers, muaj qhov pheej hmoo ntawm nws cov nyhuv nce ntxiv.
Gliformin Prolong
Hauv qee kis, tus neeg mob ntshav qab zib tau qhia Gliformin ntev ntev - Gliformin ntev. Nws yog noj ntawm qhov ncauj, ntxuav nrog qhov dej txaus. Lub cuab yeej tuaj yeem pab tau nws tus kheej lossis yog ib feem ntawm kev sib xyaw ua ke.
Yog tias cov ntshav qab zib tsis tau noj cov tshuaj metformin yav dhau los, nws raug nquahu kom pib txhaj tshuaj li 750 mg ib hnub ib zaug. Tom qab 2 lub lis piam, kws kho mob yuav hloov kho qhov tshuaj (noj 2 ntsiav tshuaj ntawm 750 mg), raws li cov txiaj ntsig kev soj ntsuam qab zib. Nrog rau qhov nce qeeb ntawm cov tshuaj, muaj qhov txo qis ntawm cov tshuaj tiv thaiv tsis zoo los ntawm qhov ua kom lub plab zom mov, tshwj xeeb, kev mob ntshav qab zib ploj mus.
Thaum cov koob tshuaj pom zoo tsis pub ua tiav kev tswj hwm ntawm glycemia, nws yog qhov tsim nyog yuav tsum tau noj ntau tshaj plaws - 3 ntsiav tshuaj ntawm 750 mg Prolong ib zaug ib hnub.
Tus mob ntshav qab zib uas noj cov tshuaj metformin ua rau tus neeg saib xyuas tso tawm tsis tu ncua:
- haus Prolong nyob rau hauv qhov sib npaug ntau npaum;
- yog tias lawv noj ntau dua 2000 mg, kev hloov pauv mus rau lub sijhawm ntev ntawm cov tshuaj tsis yog kws kho.
Yuav kom ua tau siab tshaj plaws ntawm glycemic tswj, metformin thiab cov tshuaj insulin yog siv los ua kev kho ua ke. Ua ntej, noj cov qauv tshuaj ntawm cov tshuaj (1 ntsiav tshuaj 750 mg) thaum noj hmo, thiab tus nqi ntawm cov tshuaj insulin yuav tsum tau xaiv ib tus zuj zus, raws li cov piam thaj hauv ntshav.
Qhov siab tshaj plaws nyob rau ib hnub, nws raug tso cai kom tsis pub ntau tshaj 2250 mg ntawm cov tshuaj, cov kws kho mob tshuaj xyuas tau qhia tias, muab cov xwm txheej ntawm lub cev raug tswj tau zoo, nws muaj peev xwm hloov mus rau kev noj tshuaj nrog rau kev tso tawm ib txwm muaj ntawm metformin hauv ib koob tshuaj ntawm 3000 mg.
Nws tshwm sim uas tus neeg mob tsis nco qab noj tshuaj, nyob rau hauv rooj plaub no nws tau pom tias nws yuav tsum tau noj lub ntsiav tshuaj tom ntej ntawm lub sijhawm ua ke. Koj tsis tuaj yeem noj ob zaug tshuaj metformin, qhov no yuav ua rau kev txhim kho ntawm qhov tsis zoo sab tshwm sim, ua rau cov tsos mob ntshav qab zib ntau dua, uas yuav tsum tsis txhob tso cai.
Glyformin Prolong yuav tsum noj txhua hnub, zam kev so.
Tus neeg mob yuav tsum qhia rau tus kws kho mob uas tuaj kawm txog kev txiav tu, kho nws lub tswv yim.
Cov qauv ntsuas, tshuaj xyuas ntawm kws kho mob
Vim tias muaj cov tshuaj contraindications, cov tshuaj tsis haum rau ntau tus neeg mob, nyob rau hauv rooj plaub no xav tau kev xaiv cov tshuaj analogues ntawm cov tshuaj, lawv kuj muaj qhov sib txawv ntawm cov tshuaj nquag (250, 500, 850, 1000). Gliformin tuaj yeem ua ke nrog cov tshuaj:
- Glucoran;
- Metformin Teva;
- Diaberitis
Cov neeg mob ntshav qab zib uas twb tau noj tshuaj Gliformin kho mob qhia tau tias muaj feem ntau yuav ua rau muaj kev noj ntau dhau. Feem ntau, qhov no yog vim kev siv tshuaj tsis raug cai.
Kev noj tshuaj ntau dhau tuaj yeem ua rau kev txhim kho ntawm tus mob pathological li lactic acidosis. Nws cov kev qhia tseem ceeb: mob nqaij, ntuav, xeev siab, tsis hnov qab. Thaum cov tsos mob zoo li no tshwm sim, nws pom zoo kom tsis txhob noj tshuaj.
Cov kws kho mob tau hais tias cov tshuaj Gliformin daws kev mob ntshav qab zib tau zoo heev, muab tau tias kev noj tshuaj pom zoo yuav tsum nruj me ntsis. Ib qho ntxiv ntawm cov tshuaj yog tus nqi tsim nyog thiab muaj nyob hauv cov chaw muag tshuaj.
Endocrinologist ceebtoom tias txhua ntu ntawm txoj kev kho nws yog qhov yuav tsum tau ntsuas cov kab kev rau cov ntshav cov cim dej muaj tshuaj. Cov tshuaj Glyformin rau ntshav qab zib yuav tsum tsis txhob noj ua ke:
- nrog dej cawv haus;
- tshuaj uas muaj ethanol.
Hmoov tsis zoo, ntshav qab zib tau dhau los ua cov kab mob uas haum, thiab ntawm cov neeg hluas. Txog kev kho, nws yog ib qho tsim nyog los sau tshuaj uas yuav pab kom ib txwm muaj qib glycemia, ib yam ntawm cov tshuaj yog Glyformin. Yog tias cov lus qhia rau kev siv tau ua raws nraim, cov nyhuv ntawm cov tshuaj tshwm sim hauv lub sijhawm luv.
Cov ntaub ntawv hais txog cov tshuaj ua kom muaj suab thaj muaj nyob hauv cov yeeb yaj kiab hauv tsab xov xwm no.
