Qhov tseem ceeb qhia rau kev siv Krestor yog qhov kev nce ntxiv ntawm cov roj cholesterol thaum mob hypercholesterolemia, atherosclerosis thiab lwm yam kev mob plawv.
Cov ntsiav tshuaj tau yooj yim zam los ntawm cov neeg mob, cov kev mob tshwm sim tsis tshua muaj tshwm sim. Yog tias tsim nyog, tus kws kho mob tshwj xeeb tshaj tawm kev cov ntsiab lus (Rosuvastatin, Rosart, Mertinil) lossis analogues (Atoris, Vasilip, Zokor). Cov ntaub ntawv ntxaws ntxaws dua tuaj yeem pom nyob hauv cov khoom no.
Cov ntaub ntawv siv tshuaj dav dav
Cov chaw tsim tshuaj paus yog lub tuam txhab kev lag luam AstraZeneca UK Limited, nyob hauv UK.
Crestor (Latin lub npe - Crestor) raug tso tawm hauv cov qauv ntsiav tshuaj rau kev siv sab hauv. Qhov ntau npaum li cas yuav ua tau txawv - 5, 10, 20 lossis 40 mg ntawm cov tshuaj nquag. Cov duab cardboard, uas tuaj yeem pom hauv cov duab hauv Is Taws Nem, muaj ob lub hlwv ntawm 14 ntsiav tshuaj.
Ib ntsiav tshuaj suav nrog tus nquag noj rosuvastatin calcium (rosuvastatin) thiab kev tshem tawm. Cov ntsiav tshuaj tau ua ib puag ncig lossis kheej kheej, lawv cov xim nyob ntawm qhov ntau npaum li cas - daj (5 mg) thiab paj yeeb (10, 20, 40 mg).
Tus ntoo khaub lig muaj cov nyhuv lipid-txo qis. Rosuvastatin, nce ntau ntawm cov neeg ua haujlwm rau cov nplooj siab, txo cov ntsiab lus ntawm cov "roj" phem (LDL thiab VLDL) hauv cov ntshav. Raws li qhov tshwm sim, kev faib cov roj (catabolism) thiab cov txheej txheem ntawm LDL uptake yog nrawm, thiab cov khoom lag luam ntawm cov "roj" phem tseem txo qis.
Yog li, ib lub lis piam tom qab txoj kev kho, txo qis tag nrho cov cholesterol, LDL, VLDL, triglycerides, thiab lwm yam. Qhov siab tshaj plaws ntawm kev siv cov tshuaj pom nyob tom qab 14 hnub.
Tom qab noj cov ntsiav tshuaj, qhov siab tshaj plaws ntawm cov kev ua ub no tau mus txog tom qab 5 teev. Tsis tas li ntawd, rosuvastatin khi zoo rau cov plasma protein.
Kev nqhis ntawm cov khoom tseem ceeb tshwm sim, raws li txoj cai, nrog quav thiab kom tsawg nrog zis. Kev siv ntev ntev ntawm cov tshuaj rau daim siab tuaj yeem cuam tshuam cov qauv pharmacokinetic.
Kev taw qhia thiab contraindications rau siv
Tus kws kho mob sau ntawv muab tshuaj rau hypolipidemic rau kev tiv thaiv thiab kho mob homozygous hypercholesterolemia, atherosclerosis.
Tsis tas li ntawd, cov tshuaj yog siv los kho cov hlab plawv pathologies, nrog rau kev ua ib feem ntawm txoj kev kho mob ntawm cov tshuaj sib xyaw ua ke hypercholesterolemia.
Cov lus qhia rau kev siv muaj ib daim ntawv teev ntau yam ntawm contraindications. Lawv nyob ntawm qhov ntau npaum ntawm cov tshuaj.
Nws raug txwv tsis pub siv Krestor 5.10.20 milligrams rau cov neeg uas:
- muaj kev nkag siab zoo ntxiv rau cov tshuaj uas ua kom muaj pes tsawg leeg;
- txom nyem los ntawm kev mob siab mob siab rau, nrog rau kev nce ntxiv hauv kev ua ntawm hepatic transaminases;
- tib lub sijhawm ua kev kho mob cyclosporin;
- txom nyem los ntawm lub raum tsis ua hauj lwm;
- muaj lactose intolerance lossis lactase tsis muaj peev xwm;
- tsis tau txog lub hnub nyoog 18 xyoo;
- txom nyem los ntawm myopathy (muaj kev mob siab neuromuscular pathology);
- cev xeeb tub los yog pub niam mis.
Ib koob tshuaj ntawm 40 milligrams yog contraindicated nyob rau hauv cov neeg uas:
- Haus dej cawv.
- Txom nyem los ntawm hepatic los yog lub raum tsis ua hauj lwm.
- Lawv muaj kev pheej hmoo siab myopathy.
- Coj fibrates hauv cov complex.
- Tau dhau los ntawm kev phais mob ntev ntev.
- Txom nyem los ntawm qaug dab peg, epilepsy.
- Muaj mob hypothyroidism.
- Lawv muaj qhov tsis txaus ntawm electrolytes hauv cov ntshav.
- Tsis ntev los no tau raug mob hnyav.
- Txom nyem los ntawm cov leeg ntshav hypotension.
- Tau kis tus kab mob septic.
- Txom nyem los ntawm teeb meem metabolic.
- Koom nrog Moob cov haiv neeg.
Cov ntawv qhia kev qhia tseem hais tias rau cov neeg laus (60 xyoo thiab tshaj saud), cov tshuaj yog tshuaj nrog kev ceev faj heev.
Cov lus qhia rau kev siv tshuaj
Cov neeg laus noj cov tshuaj tsis hais txog pluas noj li cas - thaum sawv ntxov lossis thaum yav tsaus ntuj. Cov ntsiav tshuaj tsis tuaj yeem chewed thiab tawg, lawv raug ntxuav nrog me me ntawm cov dej.
Cov koob tshuaj thiab lub sijhawm ntawm kev kho yog txiav txim los ntawm tus kws kho mob, coj mus rau hauv tus account yam xws li qhov mob hnyav thiab tus yam ntxwv ntawm tus neeg mob.
Raws li cov lus qhia, thawj koob tshuaj yog 5-10 milligrams. Lub chav kawm ntawm kev kho mob yog 21 hnub, so yog tsis tsim nyog. Yog tias tsim nyog, tus kws kho mob muaj cai nce cov tshuaj ntau ntxiv.
Nws raug nquahu kom koj saib xyuas tus neeg mob kev noj qab haus huv hauv thawj ob peb hnub, uas nyuam qhuav hloov mus rau Krestor 40 milligrams. Vim tias kev quav ntawm lub cev mus rau qhov nquag, cov kev txhim kho kev tsis zoo yog qhov ua tau.
Rau cov neeg uas muaj qhov nruab nrab ntawm lub raum tsis ua haujlwm, tus kws kho mob sau ib qho tshuaj pib ntawm 5 mg rau ib hnub, maj mam nce mus txog 40 mg.
Vim tias qhov tseeb ntawm cov neeg ntawm haiv neeg Mongoloid muaj qee qhov tshwj xeeb ntawm kev ua haujlwm ntawm lub siab, noj Krestor 20 thiab 40 mg yog txwv tsis pub. Thawj koob tshuaj yog 5 mg, tom qab ntawd nws tau nce ntxiv mus rau 10 mg.
Nws yog contraindicated rau tshuaj ntau dua 20 mg rau ib hnub rau cov neeg mob nquag myopathy.
Tus lipid-qis tus neeg sawv cev yuav tsum muab cia rau qhov chaw txias. Tsis txhob tso lub ntim rau hauv me nyuam yaus tes.
Txee lub neej yog 3 xyoos, tom qab lub sijhawm no, kev noj tshuaj yog qhov txwv me me.
Phiv thiab haus tshaj
Muaj qee zaus, thaum siv Krestor, cov kev mob tshwm sim yuav tshwm sim.
Raws li txoj cai, cov tshuaj tau txais txiaj ntsig zoo, thiab thaum lub sijhawm siv cov tshuaj ntau, cov kev tsis zoo tuaj yeem tuav ntawm nws tus kheej yam tsis tau nrhiav kev pab kho mob.
Cov lus qhia rau kev siv muaj cov npe hauv qab no ntawm kev phiv:
- kev ua xua - urticaria, ua pob rau ntawm daim tawv nqaij, Quincke's edema;
- mob plab tsis ua hauj lwm - tso tsis tau quav, xeev siab, ntuav, tsam plab;
- ua txhaum ntawm cov leeg poob siab - kiv taub hau thiab mob taub hau;
- muaj cov protein nyob rau hauv cov zis, qee zaum tshwm sim ntawm lub raum tsis ua haujlwm;
- mob leeg, muaj qee zaus, qhov tshwm sim ntawm myopathy;
- kev txhim kho ntawm tsis-insulin-hom (hom 2) mob ntshav qab zib mellitus;
- hepatic kawg, nce kev ua haujlwm ntawm hepatic transaminases.
Nrog kev noj tshuaj ntau dhau, cov kev mob tshwm sim nce ntxiv. Nws yog qhia nyob rau hauv kev ua txhaum ntawm kev ua haujlwm ntawm lub cev thiab txoj kev tiv thaiv ntawm lub raum thiab mob siab.
Tsis muaj cov tshuaj tua kab mob tshwj xeeb, hauv qhov no hemodialysis yog qhov tsis muaj txiaj ntsig. Txhawm rau tshem tawm ntawm kev kis dhau, kev kho mob yam ntxwv ua tau.
Ntxiv mus, kev tswj xyuas kom zoo ntawm daim siab enzymes yog qhov tsim nyog.
Lwm cov tshuaj sib cuam tshuam
Kev sib cuam tshuam ntawm Krestor nrog qee pab pawg ntawm cov tshuaj tuaj yeem ua rau qhov kev tsis txaus siab tsis zoo. Yog li, tus neeg mob yuav tsum qhia nws tus kws kho mob uas koom nrog txhua tus kab mob sib kis txhawm rau kom tsis txhob muaj kev phiv los ntawm lub cev.
Cov lus qhia tau hais txog qhov tsis xav ua ke ntawm Krestor thiab Cyclosporin. Kev siv ntawm lwm cov lipid-txo cov tshuaj tiv thaiv, piv txwv li, Hemifibrozil, hloov ntshav plasma concentration ntawm cov tshuaj nquag ntawm rosuvastatin.
Krestor muaj qhov tsis zoo nrog Warfarin thiab vitamin K antagonists, vim nws cuam tshuam rau prothrombotic Performance index.
Nws tsis pom zoo kom noj Krestor thiab Ezetimibe tib lub sijhawm, vim tias qhov no tuaj yeem nce cov zaus thiab mob hnyav ntawm cov kev mob tshwm sim.
Cov neeg mob uas nquag pib rau myopathy yuav tsum tsis txhob siv hemofibrates, fibrates, nicotinic acid, zoo li gemfibrozil nrog rosuvastatin.
Tsis tas li, kev ntxig ntxig muaj cov ntaub ntawv hais txog kev tswj hwm tsis txaus siab ntawm kev siv tshuaj tiv thaiv kab mob, tshuaj noj hauv qhov ncauj, tshuaj tiv thaiv inhibitors. Tib yam siv rau cov tshuaj xws li Erythromycin, Lopinavir thiab Ritonavir.
Hauv kev kho cov lipids siab, kev haus cawv yuav tsum nruj me ntsis.
Tus nqi thiab cov neeg siv khoom lub tswv yim
Koj tuaj yeem yuav cov tshuaj Krestor tsuas yog muaj ntawv pov thawj kws kho mob sau. Ntxiv mus, nws tau pheej yig dua xaj online ntawm lub vev xaib ntawm cov neeg sawv cev.
Tus nqi nyob ntawm tus naj npawb ntawm cov hlwv thiab ntau npaum li cas. Tus nqi ntau yog hais hauv qab no:
- 5mg (Zauv 28) nqe - 1835 rubles.
- Tus nqi krestor 10mg - 2170 rubles.
- 20 mg - 4290 rub.
- 40 mg - 6550 rub.
Yog li, cov tshuaj Krestor txawv teb yog kim, yog li ntawd, nws tsis muaj peev xwm them taus rau cov neeg mob uas tau nyiaj tsawg. Qhov no yog qhov tseem ceeb rho tawm ntawm cov tshuaj.
Txij li Krestor tau tshwm sim rau kev lag luam hauv tsev muag tshuaj hauv tsev tsis ntev dhau los, tsis muaj kev txheeb xyuas ntau yam txog nws. Nws nquag siv tshuaj rau cov tib neeg rau kev kho mob hyperlipidemia, tshwj xeeb tshaj yog tom qab mob hlab ntsha tawg lossis plawv nres.
Qee tus neeg siv khoom siv ceeb toom tias teeb meem mob taub hau thiab pw tsaug zog tshwm sim thaum kho. Cov kws tshaj lij soj ntsuam saib xyuas qhov sib txuam ntawm cov ntshav ntawm cov neeg mob, nrog rau cov lej ntawm lub siab enzymes.
Feem ntau, cov kws kho mob thiab cov neeg mob nyiam kho cov nyhuv Crestor.
Feem ntau, kev soj ntsuam zoo tuaj yeem tshawb pom txog cov tshuaj.
Cov lus ua piv txwv thiab analogues tshuaj
Yog tias Krestor contraindicated rau tus neeg mob, lossis nws muaj kev phiv tshuaj, tus kws kho mob sau ib daim qauv hloov zoo.
Qhov no tuaj yeem ua qhov sib dhos, nyob rau hauv qhov muaj pes tsawg tus uas muaj ib qho thiab tib cov kev ua haujlwm, lossis cov tshuaj tiv thaiv kab mob uas muaj cov kev kho mob tib yam, tab sis muaj cov tshuaj sib txawv.
Ntawm cov lus ua, cov ua tau zoo tshaj thiab nrov yog:
- Mertenil yog cov tshuaj pheej yig dua (450 rubles rau ib pob No. 30 rau 5 mg), uas muab cov roj (cholesterol) tsawg rau qhov ua tau zoo. Nws muaj qhov ntsuas thiab sib kis. Kev ceev faj yog noj rau hauv cov neeg mob uas muaj qhov pheej hmoo loj ntawm kev nthuav dav myopathy / rhabdomyolysis, hypothyroidism, thiab lub raum tsis ua haujlwm.
- Rosart yog lwm cov tshuaj pheej yig rau cov neeg mob uas tau nyiaj tsawg thiab nruab nrab. Qhov nruab nrab, tus nqi ntawm kev ntim khoom (No. 30 rau 5 mg) yog 430 rubles.
- Rosuvastatin, muaj tib lub npe nrog tus nquag ua ke. Nrov ntawm cov neeg mob, txij li tus nqi ntawm kev ntim khoom (No. 30 rau 5 mg) tsuas yog 340 rubles.
Cov duab zoo muaj xws li:
- Vasilip muaj lipid-txo cov nyhuv, nws cov tshuaj nquag yog simvastatin. Lub chaw tsim tshuaj paus tsim cov ntsiav tshuaj noj nrog tshuaj ntawm 10.20 thiab 40 milligrams. Tus nqi ntawm kev ntim khoom (28 ntsiav tshuaj ib 10 mg) yog 250 rubles.
- Atoris suav nrog cov tshuaj tiv thaiv nquag atorvastatin, uas ua rau kom qhov kev ua haujlwm ntawm LDL ntau ntxiv nyob rau hauv daim siab thiab cov ntaub so ntswg ntxiv. Muaj ob peb qhov kev tiv thaiv: ib tus neeg lub siab, lub siab ua rau lub siab, hloov chaw hloov chaw, lactation thiab cev xeeb tub. Tus nqi ntawm Atoris (30 ntsiav tshuaj rau 30 mg) yog 330 rubles.
- Zokor muaj simvastatin, uas suppress HMG-CoA reductase. Cov chaw tsim khoom yog Tebchaws USA thiab Netherlands. Nws muaj tib cov cim thiab contraindications li cov tshuaj yav dhau los, suav nrog thaum yau. Tus nqi ntawm kev ntim khoom (28 ntsiav tshuaj ib 10 mg) yog 385 rubles.
Yog li, koj tuaj yeem piv cov nyhuv kho thiab nqi ntawm cov tshuaj, xaiv cov kev xaiv zoo tshaj plaws. Peb yuav tsum tsis txhob hnov qab tias hauv kev tiv thaiv thiab kho kab mob atherosclerosis thiab hypercholesterolemia, koj yuav tsum ua kev tawm dag zog lub cev thiab ua raws kev noj haus.
Cov khoom noj tshwj xeeb tsis suav nrog kev noj cov rog, kib, kib, ntsev, zaub mov, thiab tais diav nrog cov roj hauv cov roj. Yog tsis muaj ob qho no, kev siv tshuaj kho mob yuav tsis tuaj yeem.
Statins tau piav qhia kom meej hauv qhov yeeb yaj kiab hauv tsab xov xwm no.
