Rosuvastatin SZ (Qaum Teb Hnub Qub) nyob nrog pab pawg ntawm cov statins uas muaj teeb meem lipid-txo qis.
Cov tshuaj tau zoo siv hauv cov kab mob cuam tshuam nrog kev txhim kho lipid metabolism, zoo li kev tiv thaiv ntawm cov kab mob plawv. Cov ntaub ntawv ntau ntxiv txog cov tshuaj muaj peev xwm nrhiav tau hauv cov khoom siv no.
Ntawm kev lag luam pharmacological, koj tuaj yeem pom ntau cov tshuaj uas muaj cov tshuaj rosuvastatin, nyob hauv ntau hom. Rosuvastatin SZ yog tsim los ntawm tus tsim khoom hauv tebchaws North Star.
Ib ntsiav tshuaj muaj 5, 10, 20, lossis 40 mg ntawm rosuvastatin calcium. Nws qhov tseem ceeb suav nrog kua mis qab zib, povidone, sodium stearyl fumarate, primellose, MCC, aerosil thiab calcium hydrophosphate dihydrate. Rosuvastatin SZ ntsiav tshuaj yog biconvex, muaj cov qauv puag ncig thiab tau them nrog lub plhaub paj yeeb.
Cov nquag ua ke yog tshuaj tiv thaiv HMG-CoA reductase. Nws qhov kev ua haujlwm yog tsom rau nce tus naj npawb ntawm hepatic LDL enzymes, txhim kho cov dissimilation ntawm LDL thiab txo lawv cov lej.
Raws li kev siv cov tshuaj, tus neeg mob tswj los txo qib ntawm cov "tsis zoo" cov roj (cholesterol) thiab nce qhov siab ntawm "zoo". Cov txiaj ntsig zoo tuaj yeem pom tau twb tau 7 hnub tom qab pib kev kho mob, thiab tom qab 14 hnub nws ua tau tiav 90% ntawm cov nyhuv siab tshaj plaws Tom qab 28 hnub, lipid metabolism rov qab mus rau qhov qub, tom qab uas yuav tsum tau kho kev kho mob.
Cov ntsiab lus siab tshaj plaws ntawm rosuvastatin raug pom nyob 5 teev tom qab kev tswj hwm ntawm qhov ncauj.
Yuav luag 90% ntawm cov tshuaj nquag khi rau albumin. Nws tshem tawm ntawm lub cev yog nqa tawm los ntawm txoj hnyuv thiab raum.
Kev taw qhia thiab contraindications rau siv
Rosuvastatin-SZ yog kho rau lipid metabolism hauv kev puas tsuaj thiab rau kev tiv thaiv cov kab mob plawv.
Raws li txoj cai, kev siv cov ntsiav tshuaj no yuav tsum ua raws li kev noj tshuaj hypocholesterol thiab kev ua kis las.
Cov ntawv qhia kev qhia muaj cov cim qhia hauv qab no rau kev siv:
- thawj, tsev neeg homozygous los yog sib xyaw hypercholesterolemia (ntxiv rau cov tshuaj tsis muaj tshuaj);
- hypertriglyceridemia (IV) yog qhov ntxiv rau cov khoom noj tshwj xeeb;
- atherosclerosis (rau inhibit qhov cia ntawm cov roj hauv plaques thiab normalize qib ntawm tag nrho cov roj (cholesterol) thiab LDL);
- kev tiv thaiv mob stroke, arterial revascularization thiab plawv nres (yog tias muaj qee yam xws li hnub nyoog laus, qib C-reactive protein, haus luam yeeb, noob caj noob ces thiab ntshav siab).
Tus kws kho mob txwv tsis pub noj tshuaj Rosuvastatin SZ 10mg, 20mg thiab 40mg yog tias nws kuaj pom hauv tus neeg mob:
- Cov tib neeg lub siab tsis haum rau Cheebtsam.
- Kev mob raum tsis zoo (nrog CC <30 ml / min).
- Cov kua dej-galactose malabsorption, tsis muaj lactase lossis lactose tsis haum.
- Hnub nyoog txog 18 xyoo;
- Kab mob siab.
- Kev nkag siab zoo ntawm cov kab mob HIV protease thiab cyclosporin blockers.
- Tshaj li qib ntawm CPK los ntawm 5 zaug lossis ntau dua qhov thaj tsam tsis sib txawv.
- Cov kab mob rau cov mob myotoxic.
- Cev xeeb tub thiab sijhawm lactation.
- Tsis muaj pov thawj (hauv cov poj niam).
Txhawm rau contraindications rau kev siv Rosuvastatin SZ nrog tshuaj 40 mg rau ntxiv rau qhov saum toj no ntxiv:
- mob raum mus rau lub raum tsis ua haujlwm;
- hypothyroidism;
- teej tug mus rau haiv neeg Moob;
- quav cawv;
- cov xwm txheej ua rau muaj kev nce qib hauv rosuvastatin ntau ntxiv.
Tsis tas li ntawd ib tug contraindication yog muaj nyob rau hauv tus kheej / tsev neeg keeb kwm ntawm cov leeg pathologies.
Cov lus qhia rau kev siv tshuaj
Cov ntsiav tshuaj yuav tsum nqos tag nrho nrog dej haus. Lawv tau noj tsis hais lub sijhawm twg los xij nyob rau hnub ntawd.
Ua ntej pib thiab thaum siv tshuaj kho mob, tus neeg mob tsis kam lees cov khoom xws li cov leeg (mob raum, mob hlwb), qe qe, nqaij npuas, lard, lwm cov roj ntsha, cov khoom noj los ntawm cov hmoov zoo, chocolate thiab khoom qab zib.
Tus kws kho mob txiav txim siab qhov ntau npaum li cas ntawm cov tshuaj raws li theem ntawm cov cholesterol, cov hom phiaj kho thiab tus yam ntxwv ntawm tus neeg mob.
Thawj koob tshuaj rosuvastatin yog 5-10 mg ib hnub twg. Yog tias nws tsis tuaj yeem ua tiav qhov txiaj ntsig uas xav tau, ntau npaum li cas ntxiv rau 20 mg nyob rau hauv kev saib xyuas nruj ntawm tus kws tshaj lij. Kev saib xyuas zoo kuj tseem ceeb thaum sau tshuaj 40 mg ntawm cov tshuaj, thaum tus neeg mob kuaj pom tias muaj tus mob hypercholesterolemia ntau heev thiab muaj feem ntau ntawm cov mob plawv.
14-28 hnub tom qab pib kev siv tshuaj, nws yog ib qho tsim nyog los soj qab cov lipid metabolism.
Tsis tas yuav hloov kho qhov ntau ntxiv ntawm cov tshuaj rau cov neeg mob laus thiab cov neeg txom nyem los ntawm lub raum tsis ua haujlwm. Nrog rau caj ces polyformism, ib qho kev nyiam rau myopathy lossis koom nrog cov haiv neeg Mooboid, cov koob tshuaj lipid-txo qis tus neeg sawv cev yuav tsum tsis pub tshaj 20 mg.
Qhov kev tswj hwm kub ntawm cia ntawm cov tshuaj ntim tsis yog ntau tshaj 25 degrees Celsius. Txee lub neej yog 3 xyoos. Khaws qhov ntim rau hauv qhov chaw tiv thaiv los ntawm ya raws thiab tshav ntuj.
Sab Caj Ces Thiab Nkawv Sib Txawv
Tag nrho cov npe ntawm cov kev mob tshwm sim uas tshwm sim thaum siv cov tshuaj tau piav qhia nyob rau hauv cov lus qhia rau kev siv.
Raws li txoj cai, kev phiv thaum noj cov tshuaj no tsis tshua muaj mob.
Txawm hais tias qhov pom ntawm qhov tshwm sim tsis zoo, lawv muaj mob me thiab ploj mus lawv tus kheej.
Hauv cov lus qhia rau kev siv, cov npe hauv qab no ntawm cov kev mob tshwm sim:
- Endocrine system: kev txhim kho ntawm qhov tsis yog-insulin-mob ntshav qab zib mellitus (hom 2).
- Kev tiv thaiv kab mob: Quincke edema thiab lwm yam kev tiv thaiv tsis pom qab.
- CNS: kiv taub hau thiab mob taub hau.
- Cov kab mob hauv lub cev: proteinuria.
- Lub plab zom mov: ua rau lub plab tsis ua hauj lwm, mob epigastric.
- Cov leeg mob: myalgia, myositis, myopathy, rhabdomyolysis.
- Daim tawv nqaij: khaus, khaus thiab ua pob.
- Biliary system: pancreatitis, ua haujlwm siab ntawm hepatic transaminases.
- Kev ntsuas kev ntsuas: hyperglycemia, theem siab ntawm bilirubin, alkaline phosphatase, GGT kev ua haujlwm, cov thyroid kawg.
Raws li cov txiaj ntsig tom qab kev tshawb fawb txog kev lag luam, kev tsis zoo tshwm sim tau txheeb xyuas:
- thrombocytopenia;
- daj thiab daj ntseg;
- Stevens-Johnson mob;
- nco tsis taus;
- ntu khoom haum;
- mob ntshav qab zib polyneuropathy;
- gynecomastia;
- hematuria;
- txog siav thiab ua pa hnoos;
- arthralgia.
Qee qhov xwm txheej, kev siv cov Rosuvastatin SZ nrog rau lwm cov tshuaj tuaj yeem ua rau cov kev tsis tuaj yeem pom. Hauv qab no yog cov yam ntxwv ntawm kev tswj hwm kev sib txuam ua ke ntawm cov tshuaj hauv cov lus nug nrog lwm tus:
- Thauj cov protein blockers - kev nce ntxiv ntawm kev pheej hmoo ntawm myopathy thiab nce ntxiv ntawm rosuvastatin.
- Cov kab mob HIV tiv thaiv kab mob tiv thaiv - muaj kev cuam tshuam ntau ntxiv ntawm cov tshuaj nquag.
- Cyclosporine - kev nce qib ntawm rosuvastatin los ntawm ntau dua 7 zaug.
- Gemfibrozil, fenofibrate thiab lwm cov fibrates, nicotinic acid - qib siab ntawm cov tshuaj nquag thiab muaj kev pheej hmoo ntawm myopathy.
- Erythromycin thiab antacids muaj aluminium thiab magnesium hydroxide - txo cov ntsiab lus ntawm rosuvastatin.
- Ezetimibe - kev nce siab hauv kev xav tau ntawm cov nquag nquag.
Txhawm rau tiv thaiv kev txhim kho ntawm cov kev tsis zoo vim tias siv cov tshuaj sib txuam ua ke, nws yog ib qho tsim nyog yuav tsum qhia rau tus kws kho mob txog txhua yam kab mob sib kis.
Nqe, tshuaj xyuas thiab analogues
Txij li cov tshuaj Rosuvastatin yog tsim los ntawm cov tshuaj cog qoob loo hauv tebchaws "North Star", nws tus nqi tsis siab dhau. Koj tuaj yeem yuav cov tshuaj hauv txhua lub tsev muag tshuaj hauv zos.
Tus nqi ntawm ib pob muaj 30 tshuaj ntawm 5 mg txhua yog 190 rubles; 10 mg txhua - 320 rubles; 20 mg txhua - 400 rubles; 40 mg rau txhua - 740 rubles.
Ntawm cov neeg mob thiab cov kws kho mob, koj tuaj yeem nrhiav ntau cov kev txheeb xyuas zoo txog cov tshuaj. Ib qho loj ntxiv yog tus nqi pheej yig thiab muaj txiaj ntsig kho tau zoo. Txawm li cas los xij, qee zaum muaj kev tshuaj xyuas tsis zoo uas cuam tshuam nrog qhov muaj tshwm sim tshwm sim.
Eugene: "Kuv nrhiav pom lipid metabolism ntev dhau los. Kuv tau sim ntau yam tshuaj rau lub sijhawm tag nrho. Kuv coj Liprimar thaum xub thawj, tab sis tawm haujlwm, vim tias nws tus nqi ntau heev. Tab sis txhua xyoo kuv yuav tsum tau ua cov tshuaj xa me me los muab cov hlab hlwb. Tom qab ntawd tus kws kho mob Krestor tau sau ntawv rau kuv, tab sis nws rov ua rau nws tsis yog cov tshuaj pheej yig. Kuv tus kheej pom nws cov analogues, ntawm cov uas yog Rosuvastatin SZ.
Tatyana: "Thaum lub caij ntuj sov, cov roj (cholesterol) nce siab mus rau 10, thaum tus qauv yog 5.8. Kuv tau mus rau tus kws kho mob thiab nws tau qhia kuv Rosuvastatin. Tus kws kho mob tau hais tias cov tshuaj no tsis tshua muaj kev cuam tshuam cov nplooj siab. Thaum lub sijhawm kuv tab tom noj Rosuvastatin SZ, hauv txoj cai, txhua yam haum tiam sis muaj ib qho “tab sis” - qee zaum mob taub hau cuam tshuam koj. "
Cov nquag ua haujlwm ntawm rosuvastatin pom nyob hauv ntau cov tshuaj tsim los ntawm cov tuam ntxhab sib txawv. Txhais cov ntsiab lus suav nrog:
- Akorta;
- Neeg Coob
- Mertenyl;
- Hlua
- Ro-Statin;
- Rosistark;
- Rosuvastatin Canon;
- Roxer;
- Xeb.
Nrog tus neeg mob siab rau rosuvastatin, tus kws kho mob xaiv cov tshuaj tiv thaiv zoo, i.e. tus neeg sawv cev uas muaj lwm qhov sib txuam, tab sis tsim tawm tib yam lipid-txo cov nyhuv. Hauv tsev muag tshuaj koj tuaj yeem yuav cov tshuaj zoo sib xws no:
- Atorvastatin.
- Atoris.
- Vasilip.
- Vero-simvastatin.
- Zokor.
- Ib Sim Neej.
Qhov loj tshaj plaws hauv kev kho mob siab cov roj ntsha siab yog ua raws li txhua qhov kev pom zoo ntawm cov kws tshaj lij tuaj koom, ua raws kev noj haus thiab ua lub neej muaj sia. Yog li, nws yuav muaj peev xwm los tswj tus mob thiab tiv thaiv ntau yam teeb meem.
Cov tshuaj Rosuvastatin SZ tau piav qhia hauv kev nthuav dav hauv video hauv kab lus no.
