Ib qho ntawm cov tshuaj nrov uas tsis yog siv tshuaj tua kab mob thiab tsis siv tshuaj tua kab mob yog cov tshuaj acetylsalicylic acid. Cov khoom muaj cov tshuaj tua kabmob (antipyretic) thiab tshuaj tiv thaiv antiplatelet (tiv thaiv platelet adhesion, tiv thaiv kom tsis txhob mob plab).
Cov tshuaj tau siv ntev hauv kev siv tshuaj, kawm zoo thiab pom tau tias yog cov tshuaj tseem ceeb. Nws tau sau npe thiab nkag mus hauv kev ua lag luam nyob rau hauv lub npe Aspirin los ntawm lub tuam txhab tshuaj German German Bayer.
Cov tshuaj aspirin muaj nyob hauv cov khoom lag luam tshuaj ntsuab: txiv apples, gooseberries, currants, txiv ntoo qab zib, txiv pos nphuab, cranberries, txiv quav ntswv nyoos, kua txob qab zib thiab lwm yam.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Acetylsalicylic acid (ASA) yog ob lub npe lag luam thiab lub npe lag luam. Hauv Latin - Acidum acetylsalicylicum.
Acetylsalicylic acid muaj qhov ua rau tshuaj tua kabmob (antipyretic) thiab antiplatelet.
ATX
ATX cov lej yog B01AC06, A01AD05, N02BA01.
Tso cov ntawv thiab cov nyob ua ke
Daim ntawv tso tawm - ntsiav tshuaj. Lawv tuaj yeem nyob rau hauv lub plhaub, tsis muaj lub plhaub, hauv cov txheej txheej enteric, effervescent, menyuam yaus. Ntim cov hlwv thiab pob duab los qhia.
Cov tshuaj phiv tshuaj ntawm cov tshuaj yog Acidum acetylsalicylicum.
Cov ntsiav tshuaj muaj xim dawb, tiaj tus, cylindrical zoo, nrog lub taub hau rau kom yooj yim nqos thiab muaj qhov phom sij ntawm ib sab.
Cov ntsiav tshuaj tuaj yeem ua rau hauv lub plhaub, tsis muaj lub plhaub, hauv txheej enteric, effervescent, rau menyuam yaus.
Mechanism ntawm kev ua
Cov tshuaj aspirin inhibits kev sib txuas ntawm thromboxane A2, txo qhov ua kom cov plasmaets thiab lawv lub peev xwm los ua cov ntshav txhaws. Cov nyhuv no mob tsawv tom qab ib koob rau lub lis piam.
Cov Tshuaj Pharmacokinetics
Cov tshuaj muaj bioavailability siab: cov tshuaj nquag yuav luag txhua yam. Qhov kev tshem tawm ib nrab-lub neej yog li 20 feeb. Qhov siab tshaj plaws hauv cov ntshav tshwm sim tom qab ob teev. Nws nkag rau ntawm lub tsho me nyuam, hla mus rau hauv niam mis. Cov tshuaj salicylates muaj nyob rau hauv dej (cerebrospinal, synovial, peritoneal), hauv cov khoom me me - hauv cov ntaub so ntswg hauv lub hlwb, kab mob muaj nyob hauv cov kua tsib, cov quav, hws.
ASA metabolism tshwm sim hauv lub siab, qhov twg plaub metabolites tau tsim los ntawm hydrolysis. Nws yog tawm los ntawm lub raum tsis hloov pauv (60%) thiab hauv daim ntawv ntawm metabolites (40%).
Cov tshuaj tawm tom qab ob lub raum tsis hloov pauv (60%) thiab hauv daim ntawv ntawm metabolites (40%).
Dab tsi pab
ASA pab nrog ntau yam mob: mob taub hau, sib koom tes, mob hniav, leeg nqaij, coj khaub ncaws. Cov tshuaj yog siv los kho cov mob febrile, cov txheej txheem ua paug, mob hlab ntsha, mob plawv, tiv thaiv kev txhim kho ntawm cov kab mob ib puag ncig, thaum lub sijhawm rov ua haujlwm tom qab kev phais mob kom tiv thaiv kev tsim cov ntshav txhaws.
Kev Taw Qhia:
- Ischemia ntawm lub plawv.
- Tsis ruaj tsis khov angina pectoris.
- Lub xub ntiag ntawm cov kev pheej hmoo cuam tshuam rau cov kab mob plawv.
- Pob Kws Ntaus Pob Kws
- Arrhythmias.
- Lub plawv tsis xws luag.
- Myocardial infarction.
- Ischemic mob stroke.
- Kev mob plawv ntawm lub plawv li qub.
- Mitral valve prolapse.
- Kab mob Kawasaki.
- Arteritis Takayasu.
- Mob rau hlwv.
- Tela.
- Pulmonary infarction.
- Thrombophlebitis ntawm cov mob hnyav.
- Mauj kab mob sclerosis ntawm cov chav kawm tau zoo.
- Ua npaws rau kis kab mob.
- Pob tsuas.
- Neuralgia
- Mob taub hau nrog intracranial siab.
Cov Yuav Tsum Muaj
- Siab zoo rau cov tshuaj nquag lossis ntxiv rau cov tshuaj ntxiv.
- Exacerbation ntawm peptic rwj ntawm lub plab zom mov.
- Txoj kev mob loj heev ntawm ob lub raum thiab mob siab.
- Hemorrhagic diathesis: telangiectasia, los ntshav ntau ntxiv.
- Lub plawv tsis ua hauj lwm.
- Bronchial hawb pob tshwm sim los ntawm NSAIDs thiab salicylates.
- Hyperuricemia
- Vitamin K tsis txaus
- Kev Hypoprothrombinemia.
- Aortic kev faib tawm.
- Thrombocytopenic purpura.
- Thrombocytopenia.
- Tus menyuam cov kabmob (thawj thiab thib peb lub txiav).
- Lactation (kev pub mis niam yuav tsum tsis ua mus ntxiv rau lub sijhawm kho mob nrog tshuaj aspirin).
- Noj cov tshuaj methotrexate hauv ib koob tshuaj 15 mg ib lis piam.
- Cov me nyuam qis dua 6 xyoo.
- Cov menyuam yaus hnub nyoog qis dua 15 xyoos rau kev kho mob ntawm kev mob ua pa.
Cov khoom sib ntxiv suav nrog kev coj tus kheej hauv lub cev.
Nrog saib xyuas
Kev ceev faj yuav tsum tau siv rau lub hlis thib ob ntawm cev xeeb tub, thaum noj nrog tshuaj anticoagulants thiab methotrexate thiab nyob rau ntawm qhov muaj cov kab mob no:
- lub plab zom mov;
- mob gout
- lub raum thiab daim siab ua haujlwm;
- ntu kev los ntshav hauv cov hnyuv;
- kev fab tshuaj rau cov tshuaj;
- hawb pob
- polyps ntawm lub qhov ntswg;
- quav nyab kub;
- COPD
- tsis muaj cov piam thaj-6-phosphate dehydrogenase.
Yuav noj tshuaj Acetylsalicylic acid li cas
ASA ntsiav tshuaj yog npaj rau kev tswj hwm qhov ncauj.
Koob tshuaj rau cov neeg laus thiab menyuam yaus txij li 12 xyoos: los ntawm 500 mg rau 1 g ib zaug, tab sis tsis ntau tshaj 3 g ib hnub. Koj tuaj yeem haus 3 zaug hauv ib hnub, sijhawm nyob nruab nrab ntawm cov koob tshuaj - tsawg kawg 4 teev.
Cov tshuaj yuav tuaj yeem qaug cawv 3 zaug nyob rau ib hnub.
Cov menyuam yaus hnub nyoog 6 txog 12 xyoo muaj cai haus tsis pub ntau tshaj 1/2 ntsiav tshuaj (250 mg) ib zaug. Cov tshuaj noj zoo yog 100-150 mg. Cov naj npawb ntawm cov txais tos txhua hnub yog los ntawm 4 txog 6.
Lub chav kho mob yam tsis muaj kws kho mob sau ntawv:
- nrog kub taub hau - txog 3 hnub;
- txhawm rau txo qhov mob - txog li 7 hnub.
Noj cov tshuaj rau ntshav qab zib
Ntawm cov ntshav qab zib (tshwj xeeb tshaj yog hom 2), cov kws kho mob pom zoo kom haus cov tshuaj Aspirin me me rau kev tiv thaiv kev mob plawv.
Kev phiv tshuaj ntawm acetylsalicylic acid
Los ntawm cov ntshav kev coagulation system
Ntshav coagulates maj mam. Tej zaum qhov kev loj hlob ntawm cov hemorrhagic syndrome: los ntshav los ntawm cov pos hniav, lub qhov ntswg.
Ntawm ib feem ntawm cov ntshav coagulation system, los ntshav los ntawm lub qhov ntswg yog tau.
Kev kho mob txoj hnyuv
Los ntawm cov hnyuv hauv plab, ntau yam phiv tuaj yeem tshwm sim:
- mob plab
- xeev siab, ntuav
- tsis qab los noj mov;
- Kev mob siab;
- ntshav hauv ntuav, cov quav dub;
- los ntshav hauv cov hnyuv;
- zawv plab
- deterioration ntawm daim siab;
- peptic rwj.
Hematopoietic plab hnyuv siab raum
Muaj kev pheej hmoo ntawm thrombocytopenia, leukopenia, ntshav liab.
Nruab nrab hauv lub paj hlwb
Nrog rau kev siv ntev, mob taub hau tshwm, pom kev thiab pob ntseg tsis hnov lus, ua mob rau daim phiaj. Nyob rau hauv cov ntaub ntawv ntawm overdose, tinnitus thiab kiv taub hau tshwm sim.
Los ntawm cov kab mob zis
Cov hlab raum tsis ua hauj lwm, cov ntshav creatinine qib nce, hypercalcemia, nephrotic syndrome, raum tsis ua hauj lwm, edema txhim kho.
Kev ua xua
Muaj cov tawv nqaij ua pob thiab khaus, muaj kev pheej hmoo ntawm kev tsim bronchospasm, Quincke's edema thiab mob anaphylactic.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Nws ntseeg tias ASA tsis cuam tshuam rau lub peev xwm tsav tsheb thiab lwm yam txheej txheem uas yuav tsum muaj kev kub siab.
Nws ntseeg tau tias ASK tsis cuam tshuam rau lub peev xwm tsav tsheb thiab lwm yam txheej txheem.
Cov lus qhia tshwj xeeb
ASA txhawb nqa los ntshav. Qhov no yuav tsum tau txiav txim siab thaum npaj rau kev phais mob, suav nrog kev tshem tawm hniav, thiab ceeb toom rau tus kws phais neeg. Nws raug nquahu kom koj tsis txhob haus cov tshuaj ib lub lis piam ua ntej kev kho mob kom tsis txhob los ntshav thaum lub sijhawm thiab tom qab phais tas.
Siv rau lub sijhawm qub
Cov kws kho mob pom zoo kom noj cov tshuaj Aspirin nyob rau hauv cov koob tshuaj me me nyob rau hauv kev saib xyuas ntawm tus kws kho mob rau cov neeg muaj hnub nyoog tshaj 60 xyoo los tiv thaiv cov kab mob plawv: mob nkees, mob plawv, ntshav txhaws.
Txiag tej menyuam
Cov menyuam yaus tsis tau sau cov tshuaj Aspirin rau kev ua npaws vim qhov mob ua pa rau lub cev, vim tias muaj kev pheej hmoo ntawm kev pheej hmoo ntawm lub neej txoj sia Reye syndrome, uas yog los ntawm kev ua rau lub siab ua rau lub siab, ua mob rau lub siab, thiab lub siab tsis ua haujlwm.
Cov menyuam yaus tsis tau sau tshuaj Aspirin rau kev ua npaws vim qhov txaus ntshai muaj kev pheej hmoo ntawm tus mob Reye syndrome.
Siv thaum cev xeeb tub thiab lactation
Hauv thawj peb lub hlis, kev noj cov tshuaj ASA tuaj yeem ua rau muaj kev txhim kho hauv lub cev hauv plab, hauv peb lub hlis nws tuaj yeem ua haujlwm qeeb, ua rau mob qog ntshav ntawm lub cev, thiab ua ntej kaw ntawm txoj hlab ntshav ntawm lub plab.
Cov tshuaj aspirin kis mus rau niam mis thiab txhawb kev tsim kho los ntshav hauv tus menyuam.
Daim ntawv thov rau lub raum khiav tsis zoo
ASA ua rau muaj kev tsis txaus ntawm uric acid los ntawm lub cev. Nws tsis pom zoo kom noj tshuaj Aspirin hauv cov neeg mob uas muaj cov ntsiab lus ntawm uric acid hauv cov ntshav thiab zis, nrog rau cov raum thiab kev txom nyem los ntawm gout.
Siv rau lub siab ua haujlwm tsis zoo
Nws yuav tsum tau ua nrog ceev faj thaum muaj teeb meem ntawm daim siab tsis ua hauj lwm thiab yog contraindicated hauv daim siab ua haujlwm.
Nws yog ib qho tsim nyog yuav tsum noj cov ntsiav tshuaj nrog ceev faj tsam muaj teeb meem ntawm daim siab ua haujlwm.
Noj tshuaj ntau dhau ntawm acetylsalicylic acid
Kev noj tshuaj ntau dhau yog ua tau nrog ib koob tshuaj ntau dhau heev lossis nrog kho ntev nrog tshuaj aspirin. Cov tsos mob ntawm me me overdose:
- kev hnov ntawm tinnitus;
- tsis muaj zog
- ntuav, xeev siab;
- hnov lus tsis zoo;
- Kiv taub hau
- tsis meej pem txog txoj kev nco qab;
- mob taub hau.
Nyob rau hauv cov mob hnyav los ntawm kev lom, cov tsos mob hauv qab no yog ua tau:
- cramps
- npaws
- coma
- poob siab
- poob hauv cov ntshav qab zib;
- lub raum thiab lub ntsws tsis ua haujlwm;
- neeg ruam;
- lub cev qhuav dej;
- pulmonary edema.
Nrog kev qaug cawv hnyav, nws yog ib qho maj nrawm hu rau lub tsheb thauj neeg mob.
Qhov tsos mob me me tshaj li ntawm Aspirin tuaj yeem yog mob taub hau.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv ua ke nrog lwm cov tshuaj, cov teebmeem hauv qab no tuaj yeem:
- Heparin thiab lwm yam tshuaj anticoagulants - kev puas tsuaj rau lub plab zom zaub mov, muaj feem yuav los ntshav.
- Methotrexate - muaj tshuaj lom ntau ntxiv ntawm methotrexate.
- Lwm cov NSAIDs yog cov muaj teeb meem ntawm lub plab zom mov thiab kev loj hlob ntawm qhov mob.
- Glucocorticosteroids (tshwj tsis yog hydrocortisone) - qhov txo qis hauv cov ntsiab lus ntawm salicylates hauv cov ntshav.
- Cov tshuaj pleev xim taub yeeb, cov tshuaj tiv thaiv tsis muaj zog, sulfonamides - cov nyhuv ntawm cov tshuaj no tau ua kom zoo dua.
- Diuretics, antihypertensive tshuaj - lawv cov hauj lwm tau txo.
- Valproic acid - nws cov kev mob toxicity nce.
- Cov kab mob hypoglycemic - lawv cov nyhuv yog kho dua.
- ACE inhibitors - cov nyhuv antihypertensive yog suppressed.
- Paracetamol - kev mob tshwm sim nce ntxiv thiab lub nra rau lub raum thiab lub siab ua kom nce ntxiv.
- Digoxin - ua rau kom cov digoxin ntau ntxiv.
- Barbiturates - kev xav ntau ntxiv hauv cov ntshav ntshav ntawm lithium ntsev.
- Benzromarone - uricosuria yog txo qis.
Cawv tau zoo
Cov kws kho mob tau ceeb toom tias ASA thiab cawv tsis sib haum. Nrog rau kev tswj hwm tib lub sijhawm, kev mob ntshav khov hauv lub plab thiab qhov chaw tiv thaiv tsis haum yog qhov ua tau.
Cov kws kho mob tau ceeb toom tias ASA thiab cawv tsis sib haum.
Analogs
Cov cim qhia tau muab nyob rau hauv cov npe lag luam: ASK-cardio, Aspikor, Fluspirin, Aspirin Cardio, Thrombo-ACC, Asprovit, Upsarin Upsa, Nektrim Fast, Taspir, Cardiomagnyl, thiab lwm yam.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Hauv cov khw muag tshuaj tau tso tawm dawb.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Tsis tas sau ntawv yuav tshuaj Aspirin tsis yuav.
Acetylsalicylic acid nqe
Tus nqi nyob ntawm qhov chaw tsim khoom thiab tus naj npawb ntawm cov ntsiav tshuaj hauv pob. Tus nqi nruab nrab yog:
- 10 daim, 0.5 g - los ntawm 5 txog 10 rubles;
- 20 pieces, 0.5 g - txog 20 rubles.
Tus nqi ntawm Aspirin yog nyob ntawm qhov chaw tsim khoom thiab tus naj npawb ntawm cov ntsiav tshuaj hauv pob.
Cia rau cov neeg mob rau cov tshuaj
Nws raug nquahu kom tshem cov tshuaj deb ntawm menyuam yaus. Nws yuav tsum khaws cia rau qhov chaw qhuav ntawm qhov kub ntawm huab cua txog 20 ° C.
Hnub tas sij hawm
Nws tuaj yeem siv tau 4 xyoos ntawm hnub uas tsim teeb meem.
Chaw tsim tshuaj paus
ASA tsim nyob rau ntau lub teb chaws: Lub teb chaws Yelemees, Switzerland, Poland, Tebchaws Asmeskas, thiab lwm yam hauv tebchaws Russia, cov tuam txhab tshuaj hauv qab no tau koom nrog Aspirin ntau lawm:
- Uralbiopharm.
- Medisorb.
- Cov Kws Muag Tshuaj.
- Tshuaj Ozone.
- Irbit KhFZ.
- Dalchimpharm.
- Borisov Hoobkas.
Hauv Lavxias, Aspirin yog tsim los ntawm lub tuam txhab tshuaj Medisorb.
Rov xyuas cov tshuaj acetylsalicylic acid
Ivan, 33 xyoo, Bryansk
Cov zoo tseem ceeb ntawm Aspirin yog tus nqi qis thiab kev ntseeg tau. Cov tshuaj yog multifunctional, zoo, saj tsis tsis phem. Kuv haus nrog mob khaub thuas, mob taub hau thiab mob hniav. Qhov qis qis yog qhov tshwm sim, nrog rau siv ntev, koj yuav tsum tiv thaiv lub plab.
Galina, 50 xyoo, Omsk
Cov tshuaj yaj yeeb yog qub, muaj pov thawj nyob rau xyoo, yog ib qho txiaj ntsig. Nws ib txwm pab nrog mob khaub thuas thiab mob mob, tab sis peb nco qab cov kev mob tshwm sim, yog li peb sim kom tsis txhob muaj mob. Tshwj xeeb tshaj yog yuav tsum tau ceev faj rau cov neeg muaj kab mob ntev ntawm lub plab thiab lwm yam plab hnyuv ntawm lub plab zom mov.
Kuv siv cov tshuaj aspirin tsis yog siv tshuaj xwb, tab sis kuj tseem siv rau hauv tsev. Yog tias koj muab cov ntsiav tshuaj tso rau hauv ib lub taub dej, cov paj yuav tsis ploj mus ntev. Lwm cov haujlwm ntawm Aspirin yog tiv thaiv qhov pom ntawm daj los ntawm hws ntawm cov khaub ncaws. Txhawm rau ua qhov no, koj yuav tsum tau dilute cov ntsiav tshuaj hauv dej thiab moisten copiously nrog cov chaw zoo. Zoo, yog tias cov pob pib tshiab, nws nyuaj rau kev tiv nrog cov qub. Kuv paub tias lawv muab nws tso rau hauv rhawv zaub thaum lawv npaj rau lub caij ntuj no, ntxiv nws rau lub ntsej muag rau pob txuv, thiab coj nws mus rau qhov tsis zoo.
Zhanna, 26 xyoo, Moscow
Ntawm thawj daim phiajcim ntawm tus mob khaub thuas, kuv haus tam sim 2 haus Aspirin ntsiav tshuaj thawm hmo. Qee lub sij hawm kuv coj nws thaum pib ua poj niam, thiab nws eases qhov mob. Nws ib txwm pab ua kom mob sai dua thiab yooj yim dua, nws ib txwm tsis ua tiav, nws pheej yig. Txwv tsis pub nws thaum cev xeeb tub thiab pub niam mis. Niam siv rau kev tiv thaiv kev mob plawv ntawm cov lus qhia los ntawm kws kho mob. Kuv paub tias nws tau raug txiav tawm rau cov ntshav thinning, nrog rau varicose leeg, thrombophlebitis, rau kev tiv thaiv ntawm thrombosis. Muaj cov kev mob tshwm sim, thiab koj tsis tas yuav hnov qab txog nws, koj tuaj yeem noj lub plab sai sai yog tias koj haus dej haus tsis tau.
Roman, 43 xyoo, Perm
Cov tshuaj pheej yig rau txhua yam, tab sis nws zoo dua tsis txhob ua phem rau nws - muaj cov contraindications thiab cov kev mob tshwm sim, Kuv qhia koj kom nyeem cov lus qhia kom zoo. Txij li thaum hnub nyoog hluas Kuv siv rau kev kho mob ua pa ceev ceev hauv tsev. Cov tshuaj zoo rau kev mob khaub thuas thiab kub taub hau: 2 Cov tshuaj Aspirin thaum tsaus ntuj thiab qhwv zoo. Qhov loj tshaj plaws yog tsis nco lub caij thiab pib ntawm qhov pib pom thawj zaug ntawm tus mob khaub thuas. Kuv haus nws nrog mob taub hau, mob taub hau qis los yog cov leeg. Kuv zam nws zoo, tab sis noj nws rau hauv cov koob tshuaj me me thiab feem ntau ib zaug.
