Diameride yog ib qho hypoglycemic tus neeg sawv cev uas tus neeg mob ntshav qab zib hom 2 coj los txo lawv cov ntshav qab zib. Kev kho nrog cov tshuaj no tshwm sim nyob rau hauv kev saib xyuas kev noj qab haus huv tas li.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Lub npe thoob ntiaj teb nonproprietary rau cov tshuaj no yog glimepiride. Nws txhais tau cov tshuaj ua tau zoo. Qhov khoom siv no yog tiam thib peb sulfonylurea derivative.
Diamerid yog cov tshuaj uas siv los txo cov ntshav piam thaj.
ATX
Txoj cai ntawm cov tshuaj raws li ATX (kev tiv thaiv lub cev, kev siv tshuaj thiab kev faib tawm tshuaj) yog A10BB12. Ntawd yog, cov tshuaj no yog ib qho cuab yeej cuam tshuam rau txoj hnyuv hauv lub plab thiab cov metabolism, yog tsim los kom tshem tawm cov ntshav qab zib, yog suav tias yog cov tshuaj hypoglycemic, lub zog ntawm sulfonylurea (glimepiride).
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv cov ntsiav tshuaj. Cov duab ntawm cov ntsiav tshuaj yog ib lub tiaj tus kheej kheej nrog bevel. Xim nyob ntawm tus nqi ntawm cov nquag siv hauv cov ntsiav tshuaj; nws yuav daj lossis liab dawb.
Cov ntsiav tshuaj tuaj yeem ntim cov tshuaj 1, 2, 3 mg lossis 4 mg ntawm cov tshuaj nquag nquag.
Cov kev zam yog: lactose monohydrate, magnesium stearate, povidone, microcrystalline cellulose, poloxamer, croscarmellose sodium, zas xim.
Ib pob muaj 3 lub hlwv, txhua tus 10 pcs.
Pharmacological kev txiav txim
Cov tshuaj no muaj cov nyhuv hypoglycemic. Kev txiav txim ntawm cov tshuaj yog ua raws li kev tsim tawm cov tshuaj insulin los ntawm beta hlwb ntawm cov leeg ntawm pancreatic islets ntawm Langerhans, ntxiv rau nce qhov kev nkag siab ntawm cov ntaub so ntswg txais rau cov tshuaj hormones thiab ua kom cov ntshav qabzib hloov cov protein ntau hauv cov ntshav. Ua raws li cov ntaub so ntswg, cov tshuaj ua rau nws lub depolarization thiab qhib kev tiv thaiv kev tiv thaiv kab mob calcium uas muaj kev tiv thaiv, vim tias qhov kev ua haujlwm ntawm tes tshwm sim.
Nws txo tus nqi ntawm gluconeogenesis nyob rau hauv daim siab vim yog qhov txhaws ntawm cov enzymes tseem ceeb, yog li muaj cov txiaj ntsig hypoglycemic.
Cov tshuaj muaj cov nyhuv hauv platelet kev sib sau, txo nws. Nws inhibits cyclooxygenase, thaiv qhov oxidation ntawm arachidonic acid, muaj cov nyhuv antioxidant, txo tus nqi ntawm lipid peroxidation.
Cov Tshuaj Pharmacokinetics
Nrog kev siv tsis tu ncua, ntawm 4 mg ib hnub twg, qhov ntau tshaj plaws ntawm cov tshuaj hauv cov ntshav pom tau 2-3 teev tom qab kev tswj hwm. Txog li 99% ntawm cov khoom sib txuas rau cov protein ntau.
Ib nrab-lub neej yog 5-8 teev, cov tshuaj yog tawm hauv daim ntawv metabolized, tsis nthuav tawm hauv lub cev. Dhau los ntawm tus me nyuam thiab hla mus rau hauv niam mis.
Kev ntsuas rau siv
Hom 2 mob ntshav qab zib mellitus, yog tias kev kho mob nrog kev noj zaub mov kom tsawg thiab ua kom lub cev tsis ua rau pom qhov txiaj ntsig.
Cov Yuav Tsum Muaj
Txais tos tsis pom zoo nyob rau hauv cov xwm txheej hauv qab no:
- yam 1 mob ntshav qab zib mellitus;
- mob ntshav qab zib coma thiab txoj kev pheej hmoo ntawm nws txoj kev loj hlob;
- hypoglycemic tej yam kev mob tshwm sim los ntawm ntau yam;
- cov qe ntshav dawb tsawg tsawg;
- mob hnyav ua rau daim siab;
- mob raum tsis zoo, siv cov khoom siv rau lub raum;
- cev xeeb tub
- pub niam mis;
- cov menyuam yaus hnub nyoog qis dua 18 xyoo;
- malabsorption syndrome thiab ua txhaum ntawm kev zom ntawm lactose.
Yuav ua li cas noj diamerid?
Thaum noj cov tshuaj, tus kws kho mob yuav tsum soj ntsuam cov qib ntawm cov piam thaj hauv cov ntshav kom xwm yeem. Tus kws kho mob tshwj xeeb txiav txim siab qhov concentration ntawm cov piam thaj hauv cov ntshav, uas yuav tsum yog tom qab noj tshuaj. Cov koob tshuaj tsawg tshaj plaws yog siv, uas cov nyhuv tsim nyog tuaj yeem ua tiav.
Cov tshuaj muaj nyob rau hauv cov ntsiav tshuaj. Cov duab ntawm cov ntsiav tshuaj yog ib lub tiaj tus kheej kheej nrog bevel.
Nrog ntshav qab zib
Thawj koob tshuaj yog 1 mg rau ib hnub. Nrog lub sijhawm ntawm 1-2 lub lis piam, kws kho mob nce qhov ntau ntxiv, xaiv qhov tsim nyog. Koj koj tus kheej tsis tuaj yeem, yam tsis tau sab laj nrog kws kho mob, pib noj tshuaj lossis hloov qhov hloov pauv, vim tias nws yog qhov muaj hwj chim kho tau, kev siv tsis raug uas yuav muaj qhov tsis zoo.
Nrog rau cov ntshav qab zib kom tau txais txiaj ntsig zoo, qhov tshuaj ntawm cov tshuaj ib hnub yog 1-4 mg, ntau dua qhov tau ntau yog tsis tshua siv vim qhov tseeb tias lawv ua rau cov neeg tsawg tsawg xwb.
Tom qab noj cov tshuaj, koj yuav tsum tsis txhob hla ib pluas noj, uas yuav tsum tau ntom. Cov kev kho mob ntev.
Siv tshuaj diameride pom zoo rau cov mob ntshav qab zib hom 2, yog tias kev kho mob nrog kev noj zaub mov kom tsawg thiab ua kom lub cev tsis zoo ua rau tsis muaj txiaj ntsig.
Phiv phiv los ntawm diamerid
Cov tshuaj no muaj cov haujlwm zoo, yog li nws muaj ntau yam kev qhia tawm.
Ntawm ib feem ntawm cov plab hnyuv siab raum ntawm lub zeem muag
Tej zaum yuav muaj teeb meem ntawm lub qhov muag: lub qhov muag tsis pom kev lossis qhov muag pom tsis zoo ntawm ib lossis ob lub plab hnyuv siab raum. Cov tsos mob zoo li no yuav tshwm sim thaum pib kho vim muaj kev hloov pauv hauv cov piam thaj.
Kev kho mob txoj hnyuv
Xeev siab, ntuav, raws plab, mob plab. Muaj kev ua txhaum nyob hauv daim siab: kab mob siab, mob daj, mob cholestasis.
Hematopoietic plab hnyuv siab raum
Tsawg cov platelet suav, cov qe ntshav dawb thiab cov qe ntshav liab, ntshav tsis txaus.
Kev phiv los ntawm diamerid: kev txo qis ntawm cov platelets, qe ntshav dawb thiab ntshav liab, ntshav tsis txaus.
Los ntawm ib sab ntawm cov metabolism
Cov ntshav qog ntshav ntshav ntev heev, uas yog nrog los ntawm xeev ntuav, mob taub hau, tsis hnov qab. ntau zog qab los noj mov, muaj kev tshaib plab tas li, tsis quav ntsej.
Kev ua xua
Ua xua: khaus, liab, liab. Muaj qee zaus, kev poob siab anaphylactic kuj yuav tshwm sim.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj muaj feem cuam tshuam rau kev muaj peev xwm los tswj cov tswv yim vim yog qhov kev txhim kho ntawm lub qog ntshav qab zib, uas nrog los ntawm kev poob qis hauv lub cev, tas mus li qaug zog thiab qaug zog. Lub peev xwm los ua haujlwm uas yuav tsum muaj kev saib xyuas tas li, suav nrog kev tsav tsheb, txo qis.
Cov lus qhia tshwj xeeb
Thaum noj, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus account yam ntxwv ntawm cov tshuaj.
Koj tsis tuaj yeem pib noj cov tshuaj lossis hloov cov tshuaj uas tau muab tshuaj rau koj tus kheej, yam tsis tau tham nrog kws kho mob.
Siv rau lub sijhawm qub
Hauv lub hnub nyoog laus, tus neeg feem ntau tsis tuaj yeem qhib kev sib txuas lus nrog nws tus kws kho mob, vim tias tus kws kho mob tsis tuaj yeem paub tus neeg mob lub sijhawm tom qab noj cov tshuaj thiab kho qhov tshuaj, uas cuam tshuam rau kev ua tau zoo ntawm kev kho thiab tus neeg mob tus mob. Yog li, tus neeg mob yuav tsum qhia tus kws kho mob txhua lub sijhawm txog kev hloov pauv hauv lub xeev, paub tias qhov no tsim nyog ua ntej ntawm nws tus kheej.
Txiag tej menyuam
Rau cov menyuam yaus hnub nyoog qis dua 18 xyoo, cov tshuaj no yog contraindicated.
Siv thaum cev xeeb tub thiab lactation
Thaum cev xeeb tub thiab thaum pub niam mis, cov tshuaj yog contraindicated vim tias nws muaj peev xwm nkag mus rau hauv qhov chaw tiv thaiv kab mob thiab tso rau hauv cov kua mis, uas tuaj yeem ua mob rau tus menyuam lub cev tsis zoo. Yog li, tus poj niam uas tau noj cov tshuaj no ua ntej xeeb tub yog hloov mus rau kev kho mob insulin.
Thaum cev xeeb tub thiab thaum pub niam mis, cov tshuaj yog contraindicated
Ntau tshaj ntawm diamerid
Yog tias dhau ntawm kev noj haus ntau dhau, qhov kev ua rau ntshav siab yog pom, uas yog nrog mob taub hau, zoo li tsis muaj zog, tawm hws, tachycardia, muaj kev ntshai thiab ntxhov siab. Yog tias cov tsos mob no tshwm sim, koj yuav tsum tau noj cov zaub mov sai sai, piv txwv li, noj ib qho qab zib. Thaum muaj mob ntau dhau ntawm cov tshuaj, nws yog ib qho tsim nyog los ntxuav lub plab lossis ua rau ntuav. Txog rau thaum lub xeev ruaj khov tiav, tus neeg mob yuav tsum nyob hauv kev saib xyuas kev noj qab haus huv, yog li ntawd thaum muaj xwm txheej hauv cov piam thaj tsawg dua, tus kws kho mob tuaj yeem muab kev pab.
Kev cuam tshuam nrog lwm yam tshuaj
Thaum siv cov tshuaj nrog lwm cov tshuaj, nws tuaj yeem ua kom tsis muaj zog lossis ntxiv dag zog rau nws txoj haujlwm, nrog rau kev hloov pauv ntawm lwm yam tshuaj, yog li nws tseem ceeb qhia rau tus kws kho mob txog cov tshuaj uas siv. Piv txwv li:
- Nrog rau kev tswj hwm tib lub sijhawm ntawm glimepiride thiab insulin, lwm yam kab mob hypoglycemic, coumarin derivatives, glucocorticoids, metformin, cov tshuaj hormones pw ua ke, angiotensin-hloov mus rau enzyme inhibitors, fluoxetine, thiab lwm yam, cov ntshav qab zib tsawg tuaj yeem tsim kho.
- Glimepiride tuaj yeem tiv thaiv lossis txhim kho cov txiaj ntsig ntawm coumarin derivatives - cov tshuaj tiv thaiv kab mob.
- Barbiturates, laxatives, T3, T4, glucagon tuaj yeem ua kom tsis muaj zog ntawm cov tshuaj, txo cov txiaj ntsig ntawm kev kho mob.
- H2 histamine receptor blockers tuaj yeem hloov kho qhov cuam tshuam ntawm glimepiride.
Nrog rau kev tswj hwm tib lub sijhawm ntawm glimepiride thiab insulin, lwm yam kab mob hypoglycemic, kev txhim kho cov ntshav khov ntau heev yog ua tau.
Cawv tau zoo
Kev haus cawv ib zaug lossis nws siv tsis tu ncua tuaj yeem hloov qhov kev ua ntawm cov tshuaj, nce los yog txo qis.
Analogs
Cov tshuaj Analogues yog cov neeg sawv cev uas muaj cov glimepiride ua cov tshuaj nquag. Cov no yog cov tshuaj xws li:
- Amaril. Nov yog tshuaj German, txhua ntsiav tshuaj ntawm muaj ib koob tshuaj 1, 2, 3 lossis 4 mg. Ntau lawm: Lub teb chaws Yelemees.
- Glimepiride Canon, Muaj cov koob tshuaj 2 lossis 4 mg. Qhuav: Russia.
- Glimepiride Teva. Muaj nyob rau hauv cov koob tshuaj 1, 2 lossis 3 mg. Ntau lawm: Croatia
Diabeton yog ib qho tshuaj tiv thaiv hypoglycemic, muaj tib yam hypoglycemic zoo, tab sis nws cov tshuaj nquag yog qhov khoom noj ntawm sulfonylurea ntawm lub cim thib ob.
Amaryl yog ib qho duab ntawm Diamerid. Nov yog tshuaj German, txhua ntsiav tshuaj ntawm muaj ib koob tshuaj 1, 2, 3 lossis 4 mg.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj muaj peev xwm yuav tau nyob ntawm txhua lub tsev muag tshuaj hauv Lavxias Federation.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Cov tshuaj yuav muab faib tawm los ntawm cov tshuaj noj.
Nqe rau diamerid
Tus nqi nruab nrab ntawm cov tshuaj yog los ntawm 202 txog 347 rubles Tus nqi nyob ntawm lub tsev muag tshuaj thiab lub nroog. Tus nqi ntawm cov analogues nyob ntawm lub teb chaws ntawm kev tsim khoom.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj yuav tsum khaws cia hauv qhov chaw tsaus, qhov kub tsis tshaj 25 ° C, nkag tsis tau rau cov menyuam yaus.
Hnub tas sij hawm
2 xyoos
Chaw tsim tshuaj paus
Nws yog tsim los ntawm Cov Tshuaj Siv Tshuaj thiab Tshuaj Siv Tshuaj AKRIKHIN AO, uas yog nyob hauv Russia.
Tshuaj thiab chaw muag tshuaj cog AKRIKHIN AO.
Kev tshuaj xyuas rau Diamerida
Ua ntej siv cov tshuaj, koj yuav tsum tau txais kev paub nrog kev txheeb xyuas txog nws.
Cov kws kho mob
Starichenko V. K .: "Cov tshuaj no yog cov txiaj ntsig zoo los tshem tawm cov ntshav qab zib hom 2. Nws raug tso cai siv nws nrog insulin lossis ua kev kho mob monotherapy. Tsuas yog tus kws kho mob tuaj yeem sau thiab kho lub koob tshuaj."
Vasilieva O.
Cov neeg mob
Galina: "Cov piam thaj hauv ntshav tau nce siab, cov tshuaj uas muaj cov tshuaj glimepiride tau sau tseg. Cov ntsiav tshuaj zoo xis, nqos zoo, noj txhua txhua hnub ua ntej noj tshais.
Natasha: "Kuv niam muaj ntshav qab zib, lwm qhov kev kho mob tsis pab, tus kws kho mob tau sau cov tshuaj, hais tias nws txhawb kev tsim cov tshuaj insulin thiab txhim kho qhov kev nkag siab ntawm cov hlwb rau nws. Qab zib yog qhov qub, nws yuav luag ib xyoos."
