Cov tshuaj Heinemox: cov lus qhia rau kev siv

Heinemox ntsiav tshuaj tuaj yeem tshem tawm qhov mob tshwm sim los ntawm kev ua haujlwm ntawm tus kab mob anaerobic, acid-resistant thiab atypical kab mob. Txhawm rau kom tsis txhob muaj qhov tsis zoo, qhov tshuaj yuav tsum tau pom zoo nrog tus kws kho mob koom nrog.

Lub Npe Tsis Yog Neeg Tsis Muaj Npe

Moxifloxacin (moxifloxacin).

ATX

J01MA14.

Antimicrobial tshuaj muaj muag nyob rau hauv daim ntawv ntawm ntsiav tshuaj ntawm 400 mg ntawm moxifloxacin.

Tso cov ntawv thiab cov nyob ua ke

Cov tshuaj tua kab mob antimicrobial muaj muag nyob rau hauv daim ntawv ntawm ntsiav tshuaj ntawm 400 mg ntawm moxifloxacin (cov tshuaj tiv thaiv nquag).

Lwm yam tshuaj hauv qhov muaj pes tsawg leeg:

• anhydrous colloidal silicon dioxide;
• croscarmellose sodium;
• cellulose microcrystals;
• magnesium stearate;
• refined talcum hmoov;
• sodium lauryl sulfate;
• 3000 macrogol;
• soya lecithin;
• oxide liab hlau;
• Hiav Txwv Dawb 85G58977.

Pharmacological kev txiav txim

Cov tshuaj belongs rau ntau tus fluoroquinolones thiab muaj cov cim suab ua haujlwm. Nquag tiv thaiv ntau cov kab mob anaerobes, atypical, tiv thaiv cov kab mob muaj peev xwm tiv thaiv kab mob (nrog rau gram-negative thiab gram-positive hom).

Cov tshuaj uas ua rau lub hauv paus ntawm cov ntsiav tshuaj tswj hwm cov DNA enzymes ntawm cov kab mob, tiv thaiv lawv txoj kev loj hlob thiab muaj peev xwm muaj me tub. Kev ua rau kev kho moxifloxacin yog ncaj qha rau kev saib xyuas ntawm cov khoom hauv cov nqaij thiab ntshav ntshav.

Nruab nrab ntawm cov txhais tau tias ntawm fluoroquinolone koob, hla-kev tsis haum tau raug kaw. Tab sis ntau cov anaerobes thiab cov kab mob gram-zoo uas tiv thaiv kab mob rau lwm cov fluoroquinolones yog qhov kev cuam tshuam los ntawm moxifloxacin ntau heev.

Cov tshuaj uas ua rau lub hauv paus ntawm cov ntsiav tshuaj tswj hwm cov DNA enzymes ntawm cov kab mob, tiv thaiv lawv txoj kev loj hlob thiab muaj peev xwm muaj me tub.

Cov Tshuaj Pharmacokinetics

Moxifloxacin yog nqus tag nrho thiab hauv lub sijhawm luv. Cmax tau ntaus hauv 30-240 feeb. Lub bioavailability ntawm MS ncav 90%. Ib theem kev nce ntxiv ntawm cov tshuaj pom nyob rau hauv lub bronchial mucous daim nyias nyias, cov hlab ntsha thiab cov nqaij ntawm lub plab ua haujlwm. Nws ua rau nrog quav thiab tso zis. Kwv yees ib nrab-lub neej yog 12 teev.

Kev ntsuas rau siv

Cov kev mob tshwm sim hauv qab no thiab sib kis tau tshwm sim los ntawm cov kab mob me me rau cov tshuaj:

• mob ntsws dej hauv zej zog tsim los ntawm Streptococcus anginosus thiab Streptococcus milleri;
• mob theem ntawm daim ntawv ntev ua mob ntsws;
• sinusitis (mob), provoked los ntawm cov kab mob pathogenic;
• Cov kab mob sib kis hauv plab (nrog rau cov kab mob polymicrobial);
• cov tawv nqaij voos thiab cov nqaij mos ua mob;
• pelvic inflammatory disease, suav nrog endometritis thiab salpingitis.

Heinemox yog kho rau kev kho kab mob ntawm lub plab mos plab hnyuv siab raum.

Nrog rau cov kab mob ntawm daim tawv nqaij, Heinemox yog tus kho.

Thrombomagum tsis tau hais kom ua kom lub ntsws tsis zoo.

Noj tshuaj yog tshuaj rau kev mob ntsws.

Nrog rau qhov mob ntshav siab, nws yog txoj kev coj los kho Heinemox.

Cov Yuav Tsum Muaj

Cov tshuaj tsis yog siv rau cov hauv qab no:

• ua xua rau cov kua taum thiab / lossis txiv laum huab xeeb;
• kev tiv thaiv tsis haum rau moxifloxacin;
• Tendon cov ntaub so ntswg kev puas tsuaj tom qab kev kho quinolone;
• ua ke nrog cov tshuaj antihistamines ncua sijhawm ntev QT ntu (Terfenadine, Astemizole), thiab tshuaj tua kab mob (Halofantrine);
• cov neeg mob uas muaj mob hnyav ntawm daim siab thiab lub raum;
• muaj hnub nyoog me.

Tus neeg sawv cev tiv thaiv kab mob tau ua kom zoo rau cov kab mob ntawm cov hlab ntsha, nrog rau kev ua kom mob hlwb, mob hlwb, ua kom tsis haum, nrog rau cov mob hepatic thiab ua ke nrog cov tshuaj noj uas txo cov poov tshuaj hauv lub cev.

Yog tias tus neeg mob ua xua rau cov kua qaub, noj cov tshuaj no txwv tsis pub.

Kev puas tsuaj rau cov ntaub so ntswg tom qab kev kho mob quinolone yog qhov sib txuam rau kev noj cov tshuaj.

Nrog rau daim ntawv me me ntawm lub raum thiab daim siab ua haujlwm, cov tshuaj yuav tsum tau ua nrog ceev faj.

Muaj hnub nyoog nyoog tsis xws luag - muaj kev sib txuam rau txoj kev siv tshuaj Heinemoks.

Yuav ua li cas noj Heinemox

Antimicrobial ntsiav tshuaj yuav tsum tau noj qhov ncauj raws li tag nrho, ntxuav nrog dej. Nws raug nquahu kom ua qhov no tom qab noj mov.

Cov tshuaj nruab nrab:

• mob ntsws (cov zej zog muaj ntau yam tshuaj): cov tshuaj yog coj nyob hauv ib koob ntawm 400 mg; kev kho mob kav ntev li 1 txog 2 lub lim tiam;
• mob ntsws (nrog exacerbation): cov tshuaj txhua hnub - 400 mg; lub sijhawm siv sijhawm yog 5-10 hnub;
• sinusitis ntawm cov kab mob ua ntej: 400 mg ntawm cov tshuaj yog kws kho ib hnub; lub sijhawm kho - 1 lub lim tiam;
• daim tawv nqaij / subcutaneous kis mob: koob tshuaj - 400 mg; lub sijhawm kho yog los ntawm 1 txog 3 asthiv;
• Kev mob ntawm txoj kev mob hauv plab: ntau npaum - 400 mg; kev kho mob lub sijhawm - los ntawm 5 mus rau 14 hnub;
• cov mob txhab (tsis pom meej), nyob hauv qhov chaw mos ntawm plab hnyuv siab: qhov nruab nrab txhua hnub - 400 mg; Lub sijhawm tso yog 2 lub lis piam.

Antimicrobial ntsiav tshuaj yuav tsum tau noj qhov ncauj raws li tag nrho, ntxuav nrog dej.

Nrog ntshav qab zib

Thaum noj tshuaj, cov neeg mob ntshav qab zib yuav tsum tau saib xyuas cov kua qab zib hauv cov ntshav.

Phiv los ntawm Heinemox

Los ntawm cov leeg nqaij thiab pob txha sib txuas

• myalgia;
• arthralgia;
• mob leeg nruj;
• mob leeg;
• tsis muaj zog
• mob caj dab;
• exacerbation ntawm myasthenia gravis;
• leeg leeg puas.

Kev kho mob txoj hnyuv

• mob plab;
• xeev siab
• zawv plab
• ua tsis taus pa;
• tsis qab los noj mov;
• mob plab
• dysphagia;
• colitis (daim ntawv pseudomembranous);
• mob hnyuv.

Thaum lub caij ua haujlwm ntawm cov tshuaj, mob leeg yuav tshwm sim.

Kev mob hauv plab yog phiv cov tshuaj Thrombomag.

Thaum kho nrog Heinemox, qhov ua kom tsis qab los noj mov yog qhov ua tau.

Cov tshuaj yuav ua rau mob plab zom mov.

Thaum noj lub plab zais plab, xeev siab thiab ntuav tej zaum yuav tshwm sim.

Hematopoietic plab hnyuv siab raum

• nce INR / lub sijhawm ntev ntawm PV;
• hloov pauv hauv thromboplastin concentration;
• leukopenia;
• neutropenia;
• thrombocythemia;
• thrombocytopenia;
• anemia

Nruab nrab hauv lub paj hlwb

• Kiv taub hau
• dysesthesia / paresthesia;
• deterioration hauv saj;
• tsis meej pem;
• insomnia
• Kev Nyuaj Siab
• xob vwj;
• nkees
• tsaug zog
• amnestic tshwm sim;
• teeb meem nrog hais lus muaj nuj nqi;
• kev hyperesthesia.

Thaum noj tshuaj, qhov ua kom pom dav dav yog tsis muaj zog.

Kev nyob tuab si taub hau yog ib phiv los ntawm kev noj tshuaj Aspirin.

Insomnia yog ib qho tshuaj phiv los ntawm cov tshuaj.

Heinemox yuav ua rau koj nkees.

Los ntawm cov hlab plawv system

• lub caij nyoog ntev ntawm QT ncua nyob rau hauv cov tib neeg kev txom nyem los ntawm hypokalemia;
• nce / txo hauv cov ntshav siab;
• ventricular tachyarrhythmia;
• cov uas tsis hais txog hom arrhythmia;
• kev tsis zoo ntawm lub siab.

Los ntawm ib sab ntawm cov metabolism

• hyperuricemia
• nce bilirubin qib;
• hyperglycemia;
• hyperlipidemia.

Kev ua xua

• eosinophilia;
• kev siv tshuaj anaphylactic;
• ua pob
• Quincke's edema;
• laryngeal o (lub neej txoj sia).

Kev hnov ​​lus tsis zoo thiab qias neeg tuaj yeem tshwm sim qee zaum.

Thaum kho nrog Heinemox, muaj kev cuam tshuam ntawm lub siab tsis tuaj yeem ua tau.

Cuam tshuam rau lub peev xwm los tswj cov tshuab

Txhais tau los ntawm qeb fluoroquinolones tuaj yeem ua rau muaj kev hloov pauv hauv cov haujlwm psychomotor thaum lawv raug coj los, yog li lub sijhawm no nws zoo dua tso tseg kev tsav tsheb thiab lwm yam kev muaj feem phom sij.

Cov lus qhia tshwj xeeb

Thaum lub sij hawm noj tshuaj, ntau qhov tshwm sim ntawm cov tsos mob ntawm daim tawv nqaij tawv nqaij raug mob (cov mob ua paug lom hauv lub cev, Stevens-Johnson syndrome). Tus neeg mob yuav tsum ceeb toom ua ntej tias yog tias muaj qhov tsis zoo tshwm sim, koj yuav tsum sab laj nrog kws kho mob sai.

Nws tsis tsim nyog yuav tsum tau siv cov tshuaj hauv kev kho mob kis mob los ntawm cov kab mob methicillin-resistant.

Siv thaum cev xeeb tub thiab lactation

Cov kws tshaj lij txwv tsis pub siv cov tshuaj no thaum lub sijhawm pub mis niam thiab cev xeeb tub.

Cov kws tshaj lij txwv tsis pub siv cov tshuaj no thaum pub niam mis.

Siv rau lub sijhawm qub

Hauv cov neeg mob no, qhov mob siab rau cov tshuaj yog nce ntau, yog li cov tshuaj yuav tsum tau xaiv noj rau hauv lawv tus kheej kev noj qab haus huv.

Txiag tej menyuam

Tsis tso cai kom txog thaum muaj 18 xyoo.

Siv rau lub siab ua haujlwm tsis zoo

Xyuam xim rau cov teeb meem hauv lub cev.

Noj tshuaj ntau ntawm Heinemox

Hauv qhov no, nws yog qhov tsim nyog yuav tsum them sai sai rau daim duab soj ntsuam. Kev noj tshuaj ntau dhau - pab txhawb, raws li saib xyuas siv ECG. Kev tswj hwm ntawm kev tawm tsam carbon tiv thaiv cov kev cuam tshuam ntau dhau ntawm moxifloxacin.

Kev tswj hwm ntawm kev tawm tsam carbon tiv thaiv cov kev cuam tshuam ntau dhau ntawm moxifloxacin.

Kev cuam tshuam nrog lwm yam tshuaj

Nrog rau kev siv ua ke nrog antacids, multivitamins thiab cov ntxhia pob zeb, kev nqus poob qis thiab cov ntshav ntawm moxifloxacin tsawg dua.

Nrog rau kev siv cov tshuaj ib txhij nrog lwm cov fluoroquinolones, muaj kev pheej hmoo ntawm kev tiv thaiv phototoxic.

Ranitidine pab txo kom tsis txhob nqus moxifloxacin.

Cawv tau zoo

Cov khw tsis muab ntaub ntawv hais txog qhov sib txuam no.

Avelox yog qhov tau tshwm sim los ntawm Heinemox tshuaj.

Cov se ntawm cov tshuaj Heinemox - Maxiflox.

Hloov chaw ntawm Heinemox, Vigamox qee lub sijhawm kho mob.

Qee zaum Rotomox yog tshuaj noj hloov Heinemox.

Analogs

• Avelox;
• Maxiflox;
• Vigamox;
• Moksimak;
• Moxigram;
• Aquamax;
• Alvelon MF;
• Ultramox;
• Simoflox;
• Rotomox;
• Plevilox;
• Moflaxia.

Cov ntsiab lus ntawm lub tsev muag tshuaj tawm

Tshuaj Ntsiav Tshuaj

Nqi

300-380 tshiav. rau ib pob No. 10 (10 ntsiav tshuaj, zaj duab xis-coated).

Cia rau cov neeg mob rau cov tshuaj

Cov tshuaj yuav tsum nyob hauv qhov chaw deb ntawm cov menyuam yaus nyob rau hauv chav tsev ntawm qhov kub tsis siab tshaj + 25 ° C.

Hnub tas sij hawm

5 xyoos

Chaw tsim tshuaj paus

Highglans Lub chaw soj nstuam HTP. LTD (Is Nrias teb).

Xyuas

Olga Shapovalova, 39 xyoo, Irkutsk

Kuv pheej haus cov tshuaj thaum kuv lub ntsws muaj mob ntau zuj zus. Nws ua qhov maj mam ua thiab yog qhov pheej yig. Kuv tau siv dua siv lwm yam tshuaj, tab sis los ntawm qhov no Kuv tsis muaj kev phiv tshuaj.

Victor Koklyushnikov, 45 xyoo, Vladimir

Nws tau raug kho nrog tshuaj kho mob rau tus mob sinusitis, raws li lawv inhibit qhov muaj peev xwm ntawm cov kab mob gram-zoo thiab gram-tsis zoo. Nws tau mus ua haujlwm nyob rau hauv 1.5 lub lis piam tom qab pib kho. Cov chaw kuaj mob rov qab mus rau qhov qub, qhov mob zoo dua qub.