Thrombomag - cov tshuaj ntawm NSAID pawg, qhia txog cov nyhuv antiplatelet. Ua tsaug rau nws, txoj kev pheej hmoo ntawm kev tsim cov kev mob tshwm sim los ntawm kev tsim cov ntshav txhaws yog txo. Tsis tas li ntawd, cov tshuaj ua rau pom lwm cov khoom, tshwj xeeb, pab ua kom tshem tawm kev mob.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Acetylsalicylic acid + Magnesium hydroxide
Thrombomag - cov tshuaj ntawm NSAID pawg, qhia txog cov nyhuv antiplatelet.
ATX
B01AC30
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yuav tau muas hauv cov ntawv hauv ncoo xwb. Nws sawv cev rau ib pawg ntawm ob-txheej txheem. Lub tebchaw nthuav qhia cov yam ntxwv tau ua los ntawm ntau lub zog. Raws li cov tshuaj yog:
- acetylsalicylic acid;
- magnesium hydroxide.
Cov ntsiav tshuaj muaj cov nqi sib txawv ntawm cov feem no. Piv txwv li, qhov koob tshuaj ASA yog 0.75 thiab 0.15 g. Magnesium chloride muaj nyob hauv 1 lub tshuaj rau qhov npaum li cas ntawm 15.2 thiab 30.39 mg. Cov ntsiav tshuaj yog coated, tab sis tsis zoo li analogues, nws raug tso cai rau grind lawv ua ntej noj. Tsis tas li ntawd, cov khoom xyaw ntawm Thrombomag suav nrog cov khoom sib txuas uas tsis ua rau pom kev tawm tsam thiab kev tawm tsam:
- pob kws nplej siab;
- qos yaj ywm hmoov txhuv nplej siab;
- microcrystalline cellulose;
- citric acid;
- magnesium stearate.
Cov tshuaj muaj rau hauv pob (3 thiab 10 pcs.), Txhua tus muaj 10 ntsiav tshuaj.
Cov tshuaj yuav tau muas hauv cov ntawv hauv ncoo xwb.
Pharmacological kev txiav txim
Lub hom phiaj tseem ceeb ntawm cov tshuaj yog rau inhibit zus ntawm thromboxane A2. Qhov tshwm sim no tau tiav los ntawm inhibiting qhov hluavtaws ntawm COX-1 isoenzymes. Txawm li cas los xij, muaj kev txo qis hauv kev siv ntawm kev tsim cov qog ua kua prostaglandins. Vim tias qhov no, qhov tshwm sim tsis zoo ntawm qhov mob tshwm sim maj mam ploj los yog lawv qhov tsis txaus ntseeg txo tsawg.
ASA muab faib rau thoob plaws lub cev, muab tsis tsuas antithrombotic, tiv thaiv kev cuam tshuam, tab sis kuj muab cov nyhuv antipyretic. Qhov kawg ntawm cov khoom yog vim muaj qhov tshwm sim muaj zog ntawm hypothalamus thiab qhov chaw nruab nrab ntawm cov thermoregulation tshwj xeeb. Tom qab noj cov tshuaj, acetylsalicylic acid yog metabolized, vim li ntawd, salicylates tawm. Cov tshuaj yeeb dej caw pab txo cov nyhuv algogenic ntawm bradykinin, vim tias muaj qhov txo qis ntawm qhov mob hnyav.
Vim tias qhov ntau ntau ntawm cov khoom uas muaj nuj nqi ASA, cov khoom siv tau nkag tau rau hauv kev sau ntawm ntau cov tshuaj. Nws cov nyhuv antiplatelet yog vim muaj peev xwm tsis tsuas yog inhibit platelet synthesis, tab sis kuj tseem txo tus nqi ntawm lawv cov kev sib txuas rau txhua tus. ASA cuam tshuam rau cov kab mob ntawm cov ntshav liab, thaum lawv cov leeg poob qis. Yog li ntawd, cov txheej txheem ntawm kev tso cov ntshav liab los ntawm cov hlab ntsha tau txais kev pabcuam, vim tias qhov ua haujlwm ntawm cov ntshav tau teev tseg li cas, nws qhov fluidity tsawg.
Cov nyhuv ntawm cov tshuaj no ntxiv rau los ntshav. Lwm cov cuab yeej ntawm ASA los ua ke yog kev tshem tawm cov ntshav txhaws. Txhua qhov cuam tshuam los ntawm cov khoom siv no sib cuam tshuam. Yog li, cov cuab yeej los tiv thaiv kev sib koom ua ke yog tau ua tiav los ntawm kev tso tawm ntawm prostaglandins, tab sis nrog lwm yam kev ua txawv. Qhov no txo qis ntawm cov qib ntawm ionized calcium, uas yuav pab txo qis kev sib xyaw ua ke ntawm cov platelets.
Cov cuab yeej ntawm ASA los ua ke yog kev tshem tawm cov ntshav txhaws.
Qhov tsis zoo ntawm cov tshuaj yog kev tsuj ntawm kev ua ke ntawm antithrombotic prostaglandins. Cov nyhuv no yog muab thaum cov tshuaj raug tshuaj rau hauv ntau npaum li cas. Qhov tshwm sim yog qhov rov tawm ntawm cov nyhuv xav tau. Vim li no, koob tshuaj txhua hnub pom zoo los ntawm tus tsim khoom lag luam (tsis pub ntau tshaj 325 mg) yuav tsum tau ua raws.
Lwm qhov sib txuam hauv cov muaj pes tsawg leeg ua rau pom cov xim antacid thiab laxative. Ua tsaug rau nws, txoj kev pheej hmoo ntawm kev tsim cov kev mob tshwm sim thaum kev kho mob raug txo qis, vim tias cov khoom no muag cov yeeb yam tsis zoo ntawm ASA rau ntawm cov qog ua haujlwm ntawm txoj hnyuv. Tom qab noj cov tshuaj, magnesium hydrochloride cuam tshuam nrog cov kua txiv ua kua plab, uas ua rau muaj kev tsim cov magnesium chloride.
Thaum cov tshuaj no nce mus txog lub plab hnyuv, nws cov nyhuv laxative yog manifested. Qhov no yog vim qhov tsis zoo muaj peev xwm yaj nyob hauv ib puag ncig zoo li no. Magnesium chloride stimulates peristalsis ntawm yam khoom hauv nruab nrog. Lwm cov cuab yeej yog qhov muaj peev xwm khi nrog cov kua tsib kua qaub. Qhov khoom siv no tau noj los ntawm lub cev maj mam, uas koom nrog nws ua ntev dua.
Tom qab noj cov tshuaj, magnesium hydrochloride cuam tshuam nrog cov kua txiv ua kua plab, uas ua rau muaj kev tsim cov magnesium chloride.
Cov Tshuaj Pharmacokinetics
Nws raug nquahu kom noj cov tshuaj cais tawm ntawm cov zaub mov, vim hais tias kev nqus ntawm cov khoom nquag yuav ua rau qeeb, uas yuav cuam tshuam rau tus nqi ntawm lawv cov tso tawm. Cov tshuaj ntawm cov tshuaj yog nqus sai, thiab tag nrho. Cov txheej txheem ntawm kev hloov pauv ntawm acetylsalicylic acid yog ntau theem. Ua ntej, salicylic acid tau tso tawm, uas tom qab ntawd txuas ntxiv nrog qhov pom ntawm ntau lub tebchaw: phenyl salicylate, glucuronide salicylate, salicyluric acid.
Kev ua haujlwm siab tshaj plaws ntawm cov tshuaj tshwm sim 10-20 feeb tom qab noj tshuaj. Kev xa tawm thoob plaws lub cev yog vim nws qhov siab khi rau cov ntshav protein. Txawm li cas los xij, txoj kev no nyob ntawm qhov ntau npaum li cas ntawm ASA: qhov loj dua cov tshuaj tau coj los, qhov phem dua cov molecules ntawm cov khoom khi rau cov ntshav protein.
Lub cev ua haujlwm kom tshem tawm ntawm cov ntshav sai sai - hauv 20 feeb, metabolites yog ncua rau lub sijhawm ntev. ASA kiag li tawm ntawm lub cev mus tom qab 1-3 hnub. Lub raum ua lub luag haujlwm rau txheej txheem ntawm tshem cov khoom tseem ceeb. Qhov kev ua haujlwm thib ob (magnesium hydrochloride) tsis cuam tshuam rau lub bioavailability ntawm acetylsalicylic acid.
Nws raug nquahu kom coj cov tshuaj cais tawm ntawm cov zaub mov.
Kev ntsuas rau siv
Qhov kev hais daws no yog tshuaj rau cov kab mob:
- thawj kev tiv thaiv ntawm ntau cov kab mob ntawm CVD: embolism thiab thrombosis ntawm leeg thiab leeg, plawv nres, yog tias muaj kev pheej hmoo: ntshav qab zib, kub siab, tus cwj pwm tsis zoo, xws li haus luam yeeb lossis haus dej cawv;
- angina pectoris ntawm kev tsis xwm yeem;
- kev tiv thaiv theem nrab ntawm myocardial infarction;
- kev tiv thaiv ntawm cov kev mob tshwm sim tom qab kev phais mob, qhov kev pheej hmoo ntawm no nce ntxiv tom qab mob hlab ntsha bypass grafting, mob hlab plawv angioplasty.
Nws puas yuav pab muaj ntshav siab?
Cov tshuaj nyob rau hauv nqe lus nug ua rau txo qis ntshav siab, tab sis rau ib tug ntau dua qhov no cov nyhuv manifests nws tus kheej tom qab noj tshuaj ua ntej mus pw. Nws yuav tsum tau yug los rau hauv lub siab tias nyob rau hauv kev cuam tshuam ntawm Thrombomag, lub siab tuaj yeem poob mus rau qhov tseem ceeb. Vim li no, nws yuav tsum tsis txhob siv thaum noj tshuaj antihypertensive.
Cov Yuav Tsum Muaj
Cov tshuaj muaj ntau yam kev txwv nyob rau lub sijhawm:
- kev puas tsuaj ntawm txoj hlab ntsws thaum kho mob nrog acetylsalicylic acid;
- cov tshuaj tiv thaiv tsis zoo ntawm ib qho tus kheej rau kev nkag ntawm ASA thiab lwm cov khoom hauv cov lus;
- teeb tsa ntawm pathologies: mob ntsws asthma, mob ntswg, txhaws ntswg, muaj qhov tsis txaus siab rau acetylsalicylic acid, qhov no, qhov pheej hmoo ua tsis taus pa nce;
- los ntshav hauv cov hnyuv;
- mob ntshav roj;
- kev txhim kho ntawm kev yaig hauv qhov kev teeb tsa ntawm phab ntsa ntawm lub zom zaws;
- kev pheej hmoo siab los ntshav (tawm tsam keeb kwm ntawm thrombocytopenia, vitamin K tsis txaus, thiab lwm yam);
- piam thaj-6-phosphate dehydrogenase tsis txaus.
Nrog saib xyuas
Muaj ntau ntau ntawm cov neeg txheeb ze sib xyaw hauv kev tso cai siv cov tshuaj, tab sis yuav tsum ceev faj:
- hyperuricemia
- mob gout
- sepsis
- yav dhau los kuaj xyuas lub plab mob thiab duodenal rwj;
- daim me me ntawm daim siab thiab lub raum tsis ua haujlwm;
- bronchial hawb pob;
- pathology ntawm cov txheej txheem ua pa;
- preoperative lub sijhawm;
- nyiam kev ua xua.
Yuav ua li cas noj thrombomag?
Feem ntau, ib koob tshuaj tsis ntau tshaj 1-2 ntsiav tshuaj hauv ib hnub yog kho. Cov tshuaj tau noj ib zaug. Txoj kev kho mob yuav txawv. Piv txwv li, txhawm rau tiv thaiv CCC cov kab mob, 150 mg ib hnub yog qhov ua ntej tshaj tawm, tom qab ntawv qhov nyiaj no txo 2 zaug. Hauv lwm qhov xwm txheej, nws pom tau tias yuav txaus noj 1 lub tshuaj nrog ib qhov tshuaj ntawm ASA (75 lossis 150 mg), uas nyob ntawm qhov mob hnyav ntawm tus kab mob.
Nrog rau daim ntawv me me ntawm lub raum thiab daim siab ua haujlwm, cov tshuaj yuav tsum tau ua nrog ceev faj.
Nrog ntshav qab zib
Cov tshuaj tau pom zoo rau kev siv, kev kho tshuaj tsis yog ua, tab sis tus neeg mob yuav tsum tau saib xyuas.
Sab sij huam ntawm Thrombomagus
Cov kev mob tshwm sim thaum kho nrog tus neeg sawv cev no tsawg dua li nrog Acetylsalicylic acid, vim tias cov khoom xyaw tseem tsawg, thiab cov nyhuv ntawm cov ntsiav tshuaj tau txuas ntxiv mus ua mos. Cov kev mob tshwm sim tshwm sim ntau:
- mob taub hau
- los ntshav
- bronchospasm;
- xeev siab thiab ntuav
- Kev mob siab.
Qhov tshwm sim ntawm cov paib no ntau dua:
- cov tsis muaj zog dav dav;
- Kiv taub hau
- hnov lus, nrog tas mus li tinnitus;
- mob ntshav roj;
- kev cuam tshuam ntawm cov kab mob hematopoietic, uas yog ua kom pom los ntawm anemia, thrombocytopenia, thiab lwm yam.
- exacerbation ntawm lub plab zom mov, uas nyob rau hauv Feem ntau muaj mob ua ntej los ntawm qhov mob ntawm lub plab;
- plaub sua;
- ntau yam kev qhia tawm ntawm kev ua xua: o ntawm txoj hlab ua pa, khaus, tawm pob, hyperemia, rhinitis;
- lub raum khiav tsis zoo.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Tsav tsheb tsis yog qhov khoom tsis sib haum. Txawm li cas los xij, vim tias qhov teeb meem loj heev tuaj yeem pib txhim kho thaum siv tshuaj kho, yuav tsum ceev faj.
Cov lus qhia tshwj xeeb
Thaum muab tshuaj rau hauv cov lus nug ua ntej kev phais mob, nws yuav tsum nco ntsoov tias cov cuab yeej los tiv thaiv kev sib txuam ntawm cov tshuaj tuaj yeem tshwm sim tsis dhau 3 hnub los ntawm cov ntsiav tshuaj kawg.
Thaum kho cov neeg mob uas kuaj pom lub raum lub raum tsis ua haujlwm, nws yog qhov yuav tsum tau saib xyuas cov cim tseem ceeb ntawm lub xeev ntawm cov khoom nruab nrog cev.
Thaum pib thiab thaum kawg theem ntawm kev kho mob, kev txheeb xyuas cov ntshav muaj pes tsawg leeg yuav tsum ua.
Siv rau lub sijhawm qub
Hauv cov neeg mob ntawm cov pab pawg no, qhov kev pheej hmoo los ntshav ntau ntxiv yog tias yuav tsum tau txhaj tsawg kawg ntawm Trobomag. Txhawm rau zam kom tsis txhob muaj teeb meem, cov ntshav thiab daim siab cov cim qhia muaj kev soj ntsuam tas li.
Hauv cov neeg laus cov neeg mob, txoj kev pheej hmoo yuav los ntshav ntaug yog tias siv tsawg kawg ntawm Trobomag noj.
Txiag tej menyuam
Tsis siv.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj tsis tau sau tseg thaum tso tes, qhov kev txwv tsuas yog siv rau I thiab III trimesters. Xws contraindications yog vim qhov kev pheej hmoo ntawm kev tsim pathologies. Qhov ntxim nyiam ntawm kev kaw ntxov ntawm tus mob qog ua ntshav hauv tus me nyuam hauv plab yog sau tseg. Lub plawv khiav tsis zoo hauv tus menyuam yuav loj hlob tuaj. Hauv lub sijhawm zaum II, nws raug tso cai siv cov tshuaj hauv qhov ntau tsis pub tshaj 150 mg rau ib hnub.
Thaum lub sijhawm pub niam mis, cov tshuaj hauv cov lus nug tseem tsis tau sau tseg.
Daim ntawv thov rau lub raum khiav tsis zoo
Ceev faj yuav tsum ua kom ib ce muaj zog, txij li cov magnesium hydrochloride tuaj yeem nkag rau hauv cov ntshav ntshav. Hauv qhov no, qhov ua kom mob ntawm lub cev nce ntxiv. Tus txheej txheem no yog ua los ntawm kev poob siab ntawm lub hauv nruab nrab cov hlab ntsha nruab nrab.
Hauv kev mob raum tsis ua haujlwm, cov tshuaj tsis raug siv. Hauv qhov xwm txheej no, koj yuav tsum mob siab rau cov creatinine tshem tawm qhov taw qhia (tsawg dua 30 ml ib feeb).
Kev mob siab rau lub siab yog txoj kev tsis ncaj rau kev noj tshuaj.
Siv rau lub siab ua haujlwm tsis zoo
Kev puas tsuaj rau lub cev no hnyav heev yog kev tiv thaiv rau kev noj cov tshuaj.
Thrombomag Tshuavd
Cov nyhuv ntawm ib tug xov tooj ntawm cov kev mob tshwm sim piav qhia saum toj no yog kho tau. Yog tias tau txhaj tshuaj loj, cov cim ntawm daim ntawv mob hnyav tshwm sim. Cov tsos mob
- npaws
- hyperventilation ntawm lub ntsws;
- ntshav tshuaj qis;
- alkalosis;
- ketoacidosis;
- kev puas tsuaj hnyav rau cov hlab plawv thiab lub tshuab ua pa ntawm lub ntsws.
Hauv qhov no, txoj kev kho nrog kev xav tau ntawm kev mob plab. Tus neeg mob tau pom zoo kom coj ib tug sorbent nyob rau hauv loj qhov ntau, hemodialysis, alkaline diuresis yog ntxiv cov kws kho mob. Kev ntsuas tab tom coj los kho cov dej-electrolyte tshuav nyiaj li cas. Thaum muaj tshuaj ntau dhau, tus neeg mob pw hauv tsev kho mob.
Nyob rau hauv cov ntaub ntawv ntawm overdose, txoj kev kho mob koom nrog lav lav lav.
Kev cuam tshuam nrog lwm yam tshuaj
Cov nyhuv ntawm methotrexate, valproic acid yog txhim kho.
Tus nab npawb ntawm cov tshuaj thiab cov tshuaj raug sau tseg, nrog rau kev tswj hwm tib lub sijhawm uas muaj qhov tsis zoo tshwm sim:
- tshuaj ntsuab yeeb tshuaj;
- NSAIDs;
- Cov tshuaj insulin
- cov tshuaj hypoglycemic;
- antiplatelet, anticoagulant thiab thrombolytic yam;
- sulfonamides;
- Digoxin;
- lithium;
- ethanol.
Cov qib kev ua haujlwm ntawm ASA raug txo qis nyob rau ntawm cov tshuaj thiab tshuaj ntau: GCS rau kev siv tshuab, Ibuprofen, lwm yam tshuaj tua kab mob, uas muaj cov tshuaj magnesium lossis aluminium hydroxide.
Cov nyhuv ntawm Methotrexate yog kho kom zoo dua thaum nws coj nrog Thrombomag.
Cawv tau zoo
Ceev faj yuav tsum tau tawm dag zog thaum kho nrog Thrombomagum, thaum haus cov cawv uas muaj cawv.
Analogs
Hloov chaw uas tuaj yeem siv es tsis txhob siv cov tshuaj hauv nqe lus nug:
- Cardiomagnyl;
- Phasostable;
- Lub Siab Mob;
- Clopidogrel Ntxiv.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj yog ib pab pawg rau cov tshuaj yuav tom khw muag tshuaj.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Muaj cov zoo li no.
Nqi
Tus nqi nws txawv ntawm 100 txog 200 rubles.
Cia rau cov neeg mob rau cov tshuaj
Pom zoo txog qhov kub thiab txias - tsis pub ntau tshaj + 25 ° С.
Hnub tas sij hawm
Nws raug tso cai siv khoom rau 2 xyoos txij li hnub tso tawm.
Chaw tsim tshuaj paus
Hemofarm, Russia.
Xyuas
Veronika, 33 xyoo, St. Petersburg.
Cov tshuaj zoo. Tom qab phais tas. Qhov tshwm sim, tsuas yog ua rau tawv nqaij tshwm sim thaum thawj theem, tsis yog. Ua tsaug rau Thrombomag, tsis muaj cov nyom, uas yog qhov tseem ceeb, vim tias kuv cov ntshav tuab heev.
Elena, hnub nyoog 42 xyoo, Alupka.
Nrog rau kub siab, nws yog ib qho tsim nyog los tswj cov koob tshuaj ntawm cov tshuaj. Yog tias koj noj nws tswj tsis tau, ntshav siab tuaj yeem poob rau qhov kev txwv tseem ceeb.Kuv muaj rooj plaub: Kuv tsis nco qab noj tshuaj kom raws sijhawm, tom qab ntawd kuv nco qab thiab haus nws tam sim ntawd, tab sis tsis ntev lub sijhawm rau koob tshuaj ntxiv yuav tsum tuaj. Kuv tsis tau coj qhov no mus rau hauv tus account thiab theej tawm cov khoom txais tos. Raws li ib tug tshwm sim, lawv nyuam qhuav pumped tawm, yog li ntawd ntau siab poob.
