Txhawm rau txiav txim siab saib qhov twg zoo dua: Phasostabil lossis Cardiomagnyl, koj yuav tsum piv cov tshuaj no los ntawm cov yam ntxwv tseem ceeb. Yog li, ua ntej ib tug xov tooj ntawm contraindications, qhia, phiv, mechanism ntawm kev txiav txim ntawm cov tshuaj thiab ib pawg ntawm lawv lub zog yog kawm. Thaum xaiv, qhov ntau npaum ntawm cov khoom nquag thiab daim ntawv tso tawm ua lub luag haujlwm.
Phasostabil yam ntxwv
Cov tshuaj nquag yog acetylsalicylic acid (ASA) thiab magnesium hydroxide. Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Nws zwm rau pab pawg ntawm cov neeg ua haujlwm antiplatelet. 1 ntsiav tshuaj muaj 75 mg ntawm ASA thiab 15.2 mg ntawm magnesium hydroxide. Cov lus sib xyaw tseem muaj lwm yam ntxiv uas tsis nthuav qhia cov haujlwm antiplatelet:
- microcrystalline cellulose;
- croscarmellose sodium;
- povidone-K25;
- magnesium stearate.
Txhawm rau txiav txim siab saib qhov twg zoo dua: Phasostabil lossis Cardiomagnyl, koj yuav tsum piv cov tshuaj no los ntawm cov yam ntxwv tseem ceeb.
Cov ntsiav tshuaj yog cov yeeb yaj kiab-txheej, uas yuav pab txo qis npaum li cas ntawm ASA thiab tiv thaiv cov leeg ntawm lub plab, nrog rau duodenum los ntawm qhov kev cuam tshuam ntawm kev siv yeeb tshuaj. Acetylsalicylic acid yog salicylic ester ntawm acetic acid. Cov tshuaj no zwm rau NSAIDs (tshuaj siv tshuaj tsis haum steroidal). Nws yog yam ntxwv los ntawm kev ua haujlwm ua ke: ASA qhia tau nws tus kheej ua ib qho kev ua kom zoo, tshem tawm cov tsos mob ntawm tus mob, thiab normalizes lub cev kub.
Lub hauv paus ntsiab lus ntawm kev ua ntawm cov khoom siv no yog ua raws li kev txwv tsis pub ua haujlwm ntawm COX isoenzymes koom nrog kev tsim khoom ntawm prostaglandin los ntawm arachidonic acid thiab thromboxane. Raws li qhov ua tiav, qhov kev siv ntau ntawm lawv cov kev tsis zoo uas ua rau lub cev txo qis. Yog li, prostaglandins koom rau hauv kev txhim kho ntawm cov txheej txheem inflammatory. Lawv cuam tshuam cov txheej txheem ntawm kev nce siab ntawm cov tau txais, yog li ua rau muaj qhov nce ntawm qhov mob.
Nyob rau hauv kev cuam tshuam ntawm prostaglandins, qhov tsis kam ntawm hypothalamic cov chaw ua lub luag haujlwm rau thermoregulation mus rau qhov tsis zoo ntawm cov kab mob pathogenic txo. ASA ib txhij suppresses txhua tus txheej txheem piav, vim qhov uas txo qis ntawm qhov kev siv ntawm o, mob thiab qhov txo qis hauv lub cev kub tau sau tseg tam sim ntawd.
Cov tshuaj nquag yog acetylsalicylic acid (ASA) thiab magnesium hydroxide.
Ntxiv rau, cov tivthaiv no tseem cuam tshuam rau cov txheej txheem platelet aggregation. Qhov no yog vim qhov tseeb tias ASA inhibits cov haujlwm ntawm endogenous thromboxane proaggregant. ASA yog tus neeg ua haujlwm tiv thaiv kabmob (antiplatelet) zoo tshaj plaws los ntawm ntau tus lej, vim nws ncaj qha cuam tshuam rau kev ua haujlwm ntawm thromboxane.
Txawm li cas los xij, acetylsalicylic acid muab cov tshuaj tiv thaiv tsis haum. Qhov no yog vim qhov tseeb tias cov tshuaj no tiv thaiv COX-1 kom ntau dua. Isoenzymes ntawm pab pawg no koom tes nrog ntau yam txheej txheem: cuam tshuam rau daim nyias nyias ntawm lub plab zom mov, lub raum ntshav khiav.
Acetylsalicylic acid tsawg feem cuam tshuam txog cyclooxygenase COX-2 enzymes, uas txhais tau hais tias nws tau qis dua rau qee cov lej ntawm qhov ntsuas hauv qhov ua tau ntawm kev tiv thaiv, analgesic zoo. Tsis tas li ntawd, thaum lub sij hawm kho nrog cov tshuaj uas muaj cov tshuaj no, muaj ntau cov kev mob tshwm sim.
Phazostabil muaj lwm txoj haujlwm tseem ceeb - magnesium hydroxide. Qhov tshuaj yeeb tshuaj no yog los ntawm pawg antacids. Nws yog tsiag ntawv los ntawm qhov ua kom zoo ntawm lub cev. Yog li, thaum noj cov tshuaj acetylsalicylic acid thiab magnesium hydroxide, cov tshuaj magnesium chloride compound raug tso tawm, vim tias qhov tshwm sim tsis zoo ntawm hydrochloric acid tsim thaum lub cev metabolism ntawm ASA yog nruab nrab.
Thaum cov tshuaj magnesium chloride nkag mus rau hauv cov hnyuv, nws ua tau nws tus kheej tias mob plab laxative.
Tsis tas li ntawd, thaum magnesium chloride nkag mus rau hauv cov hnyuv, nws ua tau nws tus kheej los ua mob quav yeeb. Qhov no yog vim qhov tseeb tias cov tshuaj no tsis yaim. Tsis tas li ntawd, ib qho kev nce siab ntawm osmotic siab hauv txoj hnyuv tau sau tseg. Tsis tas li, chloride tsim thaum lub sijhawm kev hloov pauv ntawm magnesium hydroxide magnesium chloride activates peristalsis. Qhov no yog vim qhov nce ntxiv hauv cov hnyuv thiab qhov nce siab ntxiv rau nws cov phab ntsa.
Ua tsaug rau magnesium hydroxide, ASA kev kho mob tsis pab cuam rau cov kev mob tshwm sim. Hauv cov xwm txheej huab, thaum kho, cov kev tsis zoo tshwm sim tsawg dua li nyob hauv cov kev mob thaum cov tshuaj aspirin ntshiab siv.
Pharmacokinetics ntawm Phasostabil
Cov tshuaj hauv cov lus nug tau hloov pauv rau ib lub sijhawm luv. Ntxiv mus, metabolization tshwm sim nyob rau hauv tus txheej txheem ntawm nqus.
Acetylsalicylic acid tau hloov pauv mus rau ntau dua hauv lub siab, qhov twg metabolites tso tawm, uas tau faib thoob plaws cov ntaub so ntswg thiab cov plab hnyuv siab raum. Tom qab 20 feeb, qib siab tshaj plaws ntawm ASA concentration tau tiav. Lub peev xwm los khi rau cov ntshav protein nyob ntawm qhov koob tshuaj.
Hauv kev ua haujlwm ntawm kev tshem cov acetylsalicylic acid, lub raum tau koom nrog. Qhov no txhais tau hais tias feem ntau ntawm cov tshuaj tshem tawm los ntawm kev tso zis. Thaum tsis ua kom lub raum tsis zoo, cov tshuaj tawm kom meej meej tom qab 1-3 hnub. Yog tias cov kab mob ntawm cov kab mob no loj hlob, ASA maj mam khaws ntau hauv cov xov xwm lom neeg (cov kua hauv lub cev thiab cov ntaub so ntswg). Qhov kev rau txim ntawm kev nce siab ntawm cov tshuaj no yog qhov kev txhim kho ntawm qhov muaj teeb meem, txij li cov metabolites ntawm acetylsalicylic acid muaj cov kev ua phem rau lub cev.
Hauv kev ua haujlwm ntawm kev tshem cov acetylsalicylic acid, lub raum tau koom nrog.
Kev taw qhia thiab contraindications, phiv
Phasostabil yog kho nyob rau hauv cov xwm txheej zoo li no:
- kev tiv thaiv ntawm kev txhim kho cov kab mob pathologies ntawm cov hlab plawv, tshwj xeeb, lub plawv tsis ua haujlwm, thrombosis nyob rau hauv qhov muaj kev pheej hmoo, ntawm cov uas muaj ntshav qab zib, hyperlipidemia, kub siab;
- kev tiv thaiv ntawm cov cim ntawm rov ua dua myocardial infarction;
- mob hauv siab mob;
- qhov tseem ceeb txo qis nyob rau hauv cov leeg ntshav tom qab phais vascular.
Cov tshuaj hauv cov nqe lus nug yog contraindicated hauv ntau kis:
- intolerance mus rau yam muaj sia ntawm phasostabil lossis lwm qhov tsis-steroidal anti-inflammatory tshuaj;
- mob ntshav roj;
- Vitamin K tsis txaus, uas yog lub hauv paus tseem ceeb los pab txhawb nqa qhov tshwm sim ntawm kev xav los ntshav;
- mob ntsws raum;
- kev tawm tsam ntawm tus mob ntsws asthma;
- kev sib xyaw ntawm ntau cov kab mob pathological uas ua rau ua rau lub ntsws ua tsis taus pa: mob ntsws asthma, mob qhov ntswg polyposis, tsis mob siab rau acetylsalicylic acid;
- lub sij hawm mob hnyav ntawm kev txhim kho lub plab zom mov;
- lub plab zom mov;
- siv cov tshuaj phasostabil thiab methotrexate sib xyaw;
- tsis muaj cov piam thaj-6-phosphate dehydrogenase;
- siab tsis zoo mob raum thiab mob ntshav siab muaj nuj nqi;
- lactation thiab cev xeeb tub (I thiab III trimesters);
- cov me nyuam hnub nyoog qis dua 18 xyoo
Phasostabil muaj ntau qhov kev mob tshwm sim, uas pom los ntawm cov tsos mob hauv qab no:
- kev yaig ntawm cov nqaij mos ntawm lub plab thiab txoj hnyuv;
- mob hauv plab;
- xeev siab
- gagging;
- Kev mob siab;
- perforation ntawm phab ntsa ntawm lub plab zom mov;
- o nrog cov localization ntawm qhov chaw mob hauv qhov hnyuv;
- bronchospasm;
- txo qis cov ntshav hemoglobin ntau ntau nrog anemia;
- kev hloov pauv thiab cov pov thawj hauv cov ntshav uas muaj nrog rau cov mob xws li thrombocytopenia, leukopenia, thiab lwm yam.;
- los ntshav
- kev pw tsaug zog;
- mob ntshav roj;
- hnov lus tsis zoo.
Cardiomagnyl Feature
Koj tuaj yeem yuav cov cuab yeej no hauv daim ntawv ntawm cov ntsiav tshuaj. Qhov muaj pes tsawg leeg suav nrog kev ua haujlwm zoo ib yam li hauv rooj plaub txiav txim yav dhau los: acetylsalicylic acid, magnesium hydroxide. Txawm li cas los xij, cov tshuaj tau nthuav tawm hauv cov qauv sib txawv nrog ntau qhov sib txawv ntawm cov tshuaj yeeb dej caw. 1 ntsiav tshuaj muaj: 75 lossis 150 mg ntawm ASA; 15.2 lossis 30.39 mg ntawm magnesium hydroxide. Li no, Cardiomagnyl yog tus cwj pwm los ntawm cov txheej txheem ntawm kev ua zoo ib yam li Phasostubil.
Cardiomagnyl tuaj yeem muas tau hauv cov ntawv ua ntsiav tshuaj. Qhov muaj pes tsawg leeg suav nrog kev ua kom muaj txiaj ntsig xws li acetylsalicylic acid, magnesium hydroxide.
Cov Tshuaj Sib Piv
Qhov zoo sib xws
Lub hauv paus tseem ceeb los sib xyaw cov nyiaj hauv cov lus nug yog qhov sib thooj zoo ib yam. Kev siv cov khoom ua haujlwm zoo hauv kev tsim tawm tso cai rau koj kom tau txais cov nyiaj uas ua rau ib qho kev ua tau. Vim qhov no, Cardiomagnyl thiab Phasostabil ua rau muaj kev tsis zoo ib yam. Qhov txwv nyob rau hauv kev teem ntawm cov tshuaj no kuj zoo ib yam. Siv cov tshuaj txiav txim siab nyob rau hauv kev kho mob pathological ntawm ib hom zoo sib xws.
Dab tsi yog qhov txawv?
Cardiomagnyl yog sawv cev los ntawm ob ntau yam uas sib txawv hauv cov ntau npaum. Ib txoj hauv kev yog cov analogue ncaj qha ntawm Phazostabil (nrog rau qis dua ntawm ASA thiab magnesium hydroxide). Yog li, thaum sau ntawv rau Cardiomagnyl uas muaj cov khoom xyaw nquag hauv qhov nyiaj ntawm 150 thiab 30.39 mg (hauv 1 lub ntsiav tshuaj), ib tus tuaj yeem suav rau ntawm cov nyhuv hloov zoo. Qhov txiaj ntsig zoo tau tiav nrawm dua. Txawm li cas los xij, cov kev mob tshwm sim los tsim hnyav dua. Qhov no txhais tau tias kev pheej hmoo ntawm cov nyom nce ntxiv, tshwj xeeb tshaj yog los ntawm cov hnyuv zom.
Uas yog pheej yig dua?
Phasostabil yog qhov tshuaj pheej yig dua. Nws tuaj yeem yuav rau 130 rubles. (ntim ntawv muaj 100 ntsiav tshuaj). Cardiomagnyl nrog tib cov tshuaj (75 mg thiab 15,2 mg) tus nqi 130 rubles, tab sis nyob rau hauv cov ntaub ntawv no tus nqi rau pob uas muaj 30 ntsiav tshuaj yog qhia.
Cardiomagnyl yog sawv cev los ntawm ob ntau yam uas sib txawv hauv cov ntau npaum.
Qhov twg yog qhov zoo dua: Phasostabil lossis Cardiomagnyl?
Yog tias peb sib piv cov kev npaj ua nrog rau qhov ntau npaum ntawm cov khoom xyaw dhia, lawv raug pom los ntawm tib cov neeg ua haujlwm. Hauv qhov no, qhov nqus tus nqi ntawm cov tshuaj yeeb tshuaj tsis hloov pauv, ib yam li ib nrab-lub neej ntawm cov khoom siv nquag. Raws li kev siv ntawm qhov ua tiav ntawm qhov ua tiav zoo, cov tshuaj no kuj zoo ib yam.
Yuav Cardiomagnyl hloov nrog Phasostabil?
Cov no yog cov cuab yeej sib hloov tau. Txawm li cas los xij, nyob rau hauv cov xwm txheej uas tus neeg mob tau tsim muaj qhov tsis zoo rau qee yam ntawm Cardiomagnyl, Phazostabil siv tsis tau, vim tias ob qho tshuaj yeeb tshuaj muaj cov tshuaj sib luag.
Cov kws kho mob tshuaj xyuas
Kartashova S.V., kws kho plawv, hnub nyoog 37 xyoo, Tambov
Cardiomagnyl yog kev kho mob ntau dua rau cov neeg mob uas laus dua 40 xyoo. Lub cuab yeej ua haujlwm zoo: nws ua haujlwm yuav luag tam sim ntawd, Ntxiv mus, cov kev mob tshwm sim tsis tshua muaj tshwm sim. Yog tias koj ua raws li cov txheej txheem tau hais thaum kho, ces cov teeb meem yuav tsis tshwm sim.
Maryasov A.S., kws phais neeg, 38 xyoo, Krasnodar
Phasostabil yog pheej yig dua Cardiomagnyl, tab sis txoj ntsiab cai ntawm kev ua haujlwm yog tib yam. Ob yam tshuaj puav leej zoo. Txawm li cas los xij, yog tias siv ntev heev yog qhov tsim nyog (piv txwv, txhawm rau txo cov ntshav txhaws thiab tiv thaiv cov ntshav txhaws), Kuv nyiam Phasostabil vim tias tus nqi qis.
Kev Ntsuam Xyuas Rau Neeg Mob rau Phasostable thiab Cardiomagnyl
Galina, 46 xyoo, Saratov
Tus nqi ntawm Cardiomagnyl yog qhov nruab nrab, tab sis kuv txaus siab kiag li nrog cov cuab yeej no ob qho tib si hais txog qhov ua tau zoo thiab qhov ntsuas tsis zoo rau lub plab. Kuv zam cov tshuaj kom zoo kom txog thaum muaj cov kev mob tshwm sim. Vim li no, kuv tsis xav txog lwm yam khoom siv ntxiv, suav nrog cov generics, txawm tias lawv yuav pheej yig dua.
Eugenia, 38 xyoo, St. Petersburg
Rau kuv, Phasostabil yog qhov cuab yeej zoo tshaj plaws hauv nws pawg, vim nws ua tau zoo, nws pab tshem tawm cov tsos mob ntawm lub siab tsis ua haujlwm.
