Dab tsi yog steroid mob ntshav qab zib: lus piav qhia, tsos mob, tiv thaiv

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Steroid mob ntshav qab zib mellitus tseem hu ua kab mob ntshav qab zib insulin-tso ntshav qab zib mellitus ntshav qab zib 1. Nws zoo li tshwm sim los ntawm qhov ntau dhau ntawm corticosteroids (cov tshuaj hormones ntawm adrenal cortex) hauv cov ntshav tau ntev.

Nws tshwm sim tias kev mob ntshav qab zib steroid tshwm sim vim muaj teeb meem ntawm cov kab mob uas muaj kev nce ntxiv ntawm cov tshuaj hormones, piv txwv, nrog Itsenko-Cushing's disease.

Txawm li cas los xij, feem ntau tus kab mob tshwm sim tom qab kev kho mob ntev nrog qee yam tshuaj hormonal, yog li ib ntawm cov npe ntawm tus kab mob yog ntshav qab zib tshuaj.

Cov kab mob ntshav qab zib hom mob ntshav qab zib los ntawm keeb kwm yog koom nrog pawg ntxiv ntawm kab mob, thaum xub thawj nws tsis cuam tshuam nrog kev cuam tshuam ntawm pancreatic.

Hauv cov neeg uas tsis muaj kev ntxhov siab nyob rau hauv cov khoom noj ntawm cov carbohydrate thaum muaj tshuaj ntau dhau lawm ntawm glucocorticoids, nws tshwm sim hauv cov ntawv me thiab nplooj tom qab lawv tau muab tso tseg. Hauv thaj tsam li 60% ntawm cov neeg mob, hom 2 mob ntshav qab zib ua rau kev hloov ntawm cov tshuaj insulin-ywj pheej ntawm tus kab mob mus rau ib qho kev tiv thaiv insulin.

Cov tshuaj ntshav qab zib hnyav steroid

Glucocorticoid tshuaj, xws li dexamethasone, prednisone thiab hydrocortisone, yog siv los ua cov tshuaj tiv thaiv rau:

  1. Bronchial hawb pob;
  2. Kev mob caj dab;
  3. Cov kab mob autoimmune: pemphigus, eczema, lupus erythematosus.
  4. Ntau Hom Sclerosis.

Tshuaj mob ntshav qab zib tuaj yeem tshwm sim nrog kev siv tshuaj diuretics:

  • thiazide diuretics: dichlothiazide, hypothiazide, nephrix, Navidrex;
  • tshuaj noj tiv thaiv tsis pub muaj menyuam.

Cov koob tshuaj corticosteroids loj ntau kuj tseem siv ua ib feem ntawm kev tiv thaiv mob tom qab lub raum phais tas.

Tom qab hloov chaw, cov neeg mob yuav tsum siv nyiaj rau kev tawm tsam ntawm kev tiv thaiv kev tiv thaiv rau lub neej. Cov neeg zoo li no tau nquag mob o, uas, ntawm thawj qhov chaw, hawv hem meej rau qhov hloov pauv hloov khoom nruab nrog.

Tshuaj mob ntshav qab zib tsis yog tsim nyob rau hauv txhua tus neeg mob, txawm li cas los xij, nrog kev noj cov tshuaj hormones tsis tu ncua, qhov tshwm sim ntawm nws qhov tshwm sim siab dua thaum lawv kho lwm yam kab mob.

Cov cim qhia txog ntshav qab zib uas tshwm sim los ntawm cov tshuaj steroids qhia tias tib neeg muaj kev pheej hmoo.

Txhawm rau kom tsis txhob mob, cov neeg rog yuav tsum poob; cov uas muaj lub cev hnyav yuav tsum tawm dag zog, thiab hloov pauv lawv cov zaub mov noj.

Thaum ib tus neeg paub txog nws qhov kev xav ua rau mob ntshav qab zib, tsis muaj ib qho dab tsi yuav tsum koj siv cov tshuaj hormonal raws li koj tus kheej kev txiav txim siab.

Cov yam ntxwv ntawm tus kab mob thiab cov tsos mob

Mob ntshav qab zib Steroid yog qhov tshwj xeeb hauv qhov nws ua ke ntawm cov tsos mob ntawm ob hom ntshav qab zib thiab ntshav qab zib hom 1. Tus kab mob pib thaum muaj ntau ntawm corticosteroids pib ua kom puas rau pancreatic beta hlwb.

Qhov no zoo ib yam nrog cov tsos mob ntawm tus mob ntshav qab zib hom 1. Txawm li cas los xij, beta hlwb txuas ntxiv tsim cov tshuaj insulin rau qee lub sijhawm.

Tom qab ntawd, lub ntim ntawm cov tshuaj insulin poob qis, qhov mob siab ntawm cov ntaub so ntswg rau cov tshuaj no tseem cuam tshuam, uas tshwm sim nrog ntshav qab zib 2.

Sijhawm dhau sijhawm, beta hlwb lossis qee yam ntawm lawv raug rhuav tshem, uas ua rau nres ntawm kev tsim cov tshuaj insulin. Yog li, tus kab mob pib pib zoo ib yam li cov ntshav qabzib insulin-uas ib txwm muaj. 1. Ua rau pom cov tsos mob li qub.

Cov tsos mob tseem ceeb ntawm ntshav qab zib mellitus yog tib yam li nrog txhua hom ntshav qab zib:

  1. Nce tso zis;
  2. Cawv dej;
  3. Nkees

Feem ntau, cov kev mob tshwm sim tsis qhia ntau, yog li lawv tsis tshua mob siab rau. Cov neeg mob tsis tau ua kom poob ceeb thawj, zoo li hauv ntshav qab zib hom 1, kev kuaj ntshav tsis yog ib txwm ua rau nws muaj peev xwm ua kev kuaj mob.

Cov concentration ntawm cov piam thaj hauv cov ntshav thiab cov zis tsis tshua muaj qhov txawv. Ib qho ntxiv, tseem muaj qhov txwv tsis pub muaj acetone hauv cov ntshav lossis zis tsawg.

Ntshav qab zib yog qhov pheej hmoo txaus ntshai rau cov ntshav qab zib steroid

Tus nqi ntawm cov qog adrenal nce ntxiv hauv txhua tus neeg hauv kev sib txawv. Txawm li cas los xij, tsis yog txhua tus neeg uas siv glucocorticoids muaj ntshav qab zib steroid.

Qhov tseeb yog tias ntawm ib sab tes, corticosteroids ua rau ntawm lub txiav, thiab ntawm qhov tod tes, txo cov nyhuv ntawm cov tshuaj insulin. Txhawm rau kom cov ntshav qab zib kom lub siab nyob twj ywm rau qhov qub, cov txiav yuav tsum ua haujlwm nrog lub nra hnyav.

Yog tias tus neeg muaj ntshav qab zib, tom qab ntawd qhov rhiab ntawm cov ntaub so ntswg mus rau insulin yog twb txo, thiab lub caj pas tsis tiv thaiv 100% nws lub luag haujlwm. Cov kev kho steroid yuav tsum ua kom yog qhov chaw kawg. Txoj kev pheej hmoo yog nce nrog:

  • kev siv cov tshuaj steroids hauv siab;
  • lub caij nyoog siv steroids;
  • thawj tus neeg mob rog.

Kev saib xyuas yuav tsum tau ua rau kev txiav txim siab nrog cov uas qee zaum muaj ntshav qab zib cov ntshav siab vim tias tsis muaj laj thawj.

Siv glucocorticoids, qhov tshwm sim ntawm ntshav qab zib nce ntxiv, thiab qhov no ua rau tib neeg xav tsis thoob, vim tias nws tsis tuaj yeem paub txog nws cov ntshav qab zib.

Hauv qhov no, ntshav qab zib tau me ntsis ua ntej glucocorticoids tau noj, uas txhais tau hais tias cov tshuaj tiv thaiv hormonal sai sai ua rau mob thiab yuav txawm ua rau muaj mob xws li mob ntshav qab zib tsis xeev.

Ua ntej sau cov tshuaj hormonal, cov neeg laus thiab cov poj niam rog dhau yuav tsum tau kuaj mob ntshav qab zib latent.

Kho ntshav qab zib

Yog tias lub cev tseem tsis tau muaj cov insulin ntau lawm, tom qab ntawd cov ntshav qab zib tshuaj, zoo li ntshav qab zib hom 1, tab sis nws muaj cov yam ntxwv ntawm ntshav qab zib hom 2, uas yog, insulin tsis kam ntawm cov ntaub so ntswg. Tus mob ntshav qab zib no kho mob ntshav qab zib 2.

Kev kho yog nyob ntawm, thiab lwm yam, ntawm yam mob uas tus neeg mob muaj. Piv txwv, rau cov neeg rog dhau los uas tseem tsim cov tshuaj insulin, kev noj zaub mov kom ntshav qab zib thiab cov tshuaj muaj suab thaj xws li thiazolidinedione thiab glucophage tau qhia. Ntxiv rau:

  1. Yog tias muaj lub cev ua haujlwm pancreatic txo qis, tom qab ntawd cov lus qhia ntawm insulin yuav ua rau nws txo qis lub nra.
  2. Thaum tsis tiav ntawm atrophy ntawm beta hlwb, dhau sijhawm, kev ua haujlwm pancreatic pib rov zoo dua.
  3. Rau tib lub hom phiaj, kev noj zaub mov kom tsawg carb yog tsim nyog.
  4. Rau cov tib neeg muaj qhov hnyav, noj zaub mov noj haus No. 9 raug pom zoo; cov neeg rog dhau los yuav tsum ua raws li kev noj haus zaub mov 8.

Yog tias tus txiav tsis tsim cov tshuaj insulin, tom qab ntawd nws raug sau los ntawm kev txhaj tshuaj thiab tus neeg mob yuav tsum paub txog kev txhaj tshuaj insulin kom raug. Kev tswj cov ntshav qab zib thiab kev kho mob tau ua tiav zoo ib yam li mob ntshav qab zib 1. Ntxiv mus, cov kab mob hlwb tuag tsis tuaj yeem rov qab tuaj.

Ib qho kev sib cais tshwj xeeb ntawm kev siv tshuaj kho mob ntshav qab zib yog qhov xwm txheej uas nws tsis tuaj yeem tsis lees txais kev kho tshuaj hormone, tab sis tus neeg muaj mob ntshav qab zib. Qhov no yog tom qab lub raum hloov ntshav lossis muaj mob hawb pob hnyav.

Cov suab thaj tau tswj xyuas nyob ntawm no, raws li kev nyab xeeb ntawm cov txiav thiab theem ntawm cov ntaub so ntswg muaj feem cuam rau insulin.

Raws li kev txhawb nqa ntxiv, cov neeg mob tuaj yeem yog cov ncauj lus anabolic uas ua rau sib luag ntawm cov tshuaj glucocorticoid.

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