Gensulin yog cov tshuaj kho mob rau kev txhaj tshuaj rau ntshav qab zib. Nws yog contraindicated nyob rau hauv cov ntaub ntawv ntawm ntau rhiab heev rau nws, raws li tau zoo raws li hypoglycemia.
Cov lus qhia rau kev siv thiab ntau npaum li cas
Qhov kev txhaj thiab qhov tshwj xeeb ntawm kev tswj hwm yuav raug pom zoo los ntawm tus kws kho mob nkaus xwb. Qhov ntau npaum li cas yuav raug teem raws li kev xav txog cov ntshav qab zib tam sim no thiab 2 teev tom qab noj mov. Tsis tas li ntawd, qhov kev kawm tiav ntawm chav kawm ntawm glucosuria thiab nws cov yam ntxwv yuav raug coj los siv.
Gensulin r tuaj yeem siv ntau txoj hauv kev (intravenously, intramuscularly, subcutaneously) 15-30 feeb ua ntej kev npaj pluas noj. Cov txheej txheem nrov tshaj plaws ntawm kev tswj hwm yog subcutaneous. Tus so yuav tsim nyog nyob rau hauv cov xwm txheej zoo li no:
- nrog cov ketoacidosis uas mob ntshav qab zib;
- nrog mob plab zuag;
- thaum phais.
Qhov ntau zaus ntawm kev tswj hwm thaum lub sij hawm siv los kho lub cev muaj zog yuav yog 3 zaug hauv ib hnub. Yog tias tsim nyog, cov lej tuaj yeem nce ntxiv txog 5-6 zaug hauv ib hnub.
Txhawm rau kom tsis txhob txhim kho lipodystrophy (atrophy thiab hypertrophy ntawm subcutaneous cov ntaub so ntswg), nws yog ib qho tsim nyog yuav tsum hloov pauv ntawm thaj chaw txhaj tshuaj.
Qhov nruab nrab txhua hnub ntau npaum li cas ntawm cov tshuaj Gensulin r yuav yog:
- rau cov neeg mob laus - los ntawm 30 txog 40 units (UNITS);
- rau menyuam yaus - 8 seem.
Ntxiv mus, nrog rau qhov kev thov nce ntxiv, qhov nruab nrab koob yuav yog 0.5 - 1 UNITS hauv ib phaus ntawm qhov hnyav, lossis los ntawm 30 txog 40 UNITS 3 zaug hauv ib hnub.
Yog tias qhov koob tshuaj txhua hnub yuav tshaj 0.6 PIECES / kg, tom qab ntawv no qhov tshuaj yuav tsum raug txhaj 2 koob rau hauv ntau qhov chaw ntawm lub cev.
Tshuaj muab rau qhov muaj peev xwm los sib txuas nrog tshuaj Gensulin r nrog insulins ntev ntev.
Kev daws yuav tsum tau sau los ntawm vial los ntawm kev tho lub taub roj hmab nrog lub hau huv lub koob txhaj tshuaj.
Lub hauv paus ntsiab lus ntawm kev kov lub cev
Cov tshuaj no cuam tshuam nrog cov receptors tshwj xeeb rau ntawm daim nyias nyias cov qe. Raws li qhov tshwm sim ntawm qhov sib tiv tauj ntawd, ib qho insulin receptor complex tshwm sim. Raws li kev tsim cov khoom cAMP nce rau hauv cov rog thiab lub siab lossis thaum nws nkag ncaj qha rau cov leeg nqaij, qhov tshwm sim ntawm insulin receptor pib nthuav tawm cov txheej txheem intracellular.
Txoj kev poob rau hauv cov ntshav qab zib yog tshwm sim los ntawm:
- kev loj hlob ntawm nws txoj kev thauj khoom intracellular;
- ntxiv kev nqus, nrog rau nws txoj kev nqus los ntawm cov ntaub so ntswg;
- kev txhawb nqa ntawm cov txheej txheem ntawm lipogenesis;
- protein synthesis;
- glycogenesis;
- qhov txo qis hauv cov nqi ntawm cov piam thaj tsim tawm los ntawm lub siab.
Tom qab txhaj tshuaj subcutaneous, cov tshuaj Gensulin r yuav pib ua li ntawm 20-30 feeb. Qhov siab tshaj plaws ntawm cov tshuaj yuav pom tau tom qab 1-3 teev. Lub sijhawm tiv thaiv ntawm cov tshuaj insulin no yuav ncaj qha nyob ntawm seb qhov ntau npaum li cas, hom kev thiab qhov chaw tswjhwm.
Qhov ntxim nyiam ntawm kev tshwm sim tsis zoo
Hauv kev ua los ntawm kev thov Gensulin r cov kev tsis zoo hauv qab no ntawm lub cev yog ua tau:
- kev ua xua (urticaria, ua pa ceev ceev, ua npaws, txo cov ntshav siab);
- hypoglycemia (pallor ntawm daim tawv nqaij, tawm hws, nce hws, tshaib plab, tshee tshee, ntxhov siab dhau, mob taub hau, nyuaj siab, coj txawv txawv, tsis pom kev thiab ua kom sib haum);
- hypoglycemic coma;
- diabetic acidosis thiab hyperglycemia (muaj kev txhim kho nrog cov tshuaj tsis haum tshuaj, hla kev txhaj tshuaj, tsis kam noj zaub mov noj): lub ntsej muag tawv nqaij hyperemia, lub ntsej muag ua kom tsis qab los noj mov, tsaug zog, nqhis dej;
- tsis nco qab zoo;
- cov teeb meem kev pom hloov pauv;
- cov tshuaj tiv thaiv kab mob ntawm lub cev rau tib neeg cov tshuaj insulin.
Tsis tas li ntawd xwb, thaum pib kho mob, yuav muaj o thiab ua kom lub siab tsis zoo. Cov tsos mob no yog qhia dag thiab ploj sai.
Daim ntawv thov nta
Ua ntej koj noj cov tshuaj Gensulin r los ntawm ib lub vial, koj yuav tsum tshawb xyuas qhov kev daws teeb meem rau pob tshab. Yog hais tias lub cev txawv teb chaws, kev poob qis lossis kev xeb ntawm ib yam khoom raug tshawb pom, nws raug txwv tsis pub siv!
Nws yog ib qho tseem ceeb kom tsis txhob hnov qab txog qhov zoo tshaj plaws kub ntawm cov tshuaj txhaj - nws yuav tsum yog chav sov.
Qhov ntau thiab tsawg ntawm cov tshuaj yuav tsum tau kho nyob rau hauv cov ntaub ntawv ntawm kev loj hlob ntawm tej yam kab mob:
- kis tau;
- Addison tus kab mob;
- nrog rau cov ntshav qab zib hauv cov neeg mob laus dua 65 xyoo;
- muaj teeb meem hauv kev ua haujlwm ntawm cov thyroid caj pas;
- Kev Ntsuas Ncaj.
Cov ntsiab lus tseem ceeb rau kev txhim kho ntshav qab zib tuaj yeem dhau los: kev noj ntau dhau, hloov tshuaj, ntuav, kho lub plab, hloov qhov chaw txhaj tshuaj, mob lub cev, nrog rau kev sib cuam tshuam nrog qee yam tshuaj.
Yuav pom ib qho kev txo qis hauv cov ntshav qab zib tuaj yeem pom thaum hloov los ntawm tsiaj cov insulin rau tib neeg.
Txhua yam kev hloov pauv ntawm cov tshuaj raug tswj yuav tsum ua kom raug kuaj mob thiab ua raws li kev saib xyuas los ntawm tus kws kho mob nruj tshaj plaws. Yog tias muaj qhov mob siab rau qhov kev txhim kho hypoglycemia, tom qab no qhov no muaj peev xwm ntawm cov neeg mob koom nrog hauv kev tsheb khiav tsheb thiab kev saib xyuas ntawm cov tshuab, thiab hauv cov tsheb tshwj xeeb, tej zaum yuav raug mob.
Tus mob ntshav qab zib tuaj yeem ywj pheej nres kev txhim kho rau cov neeg muaj ntshav qab zib tsawg. Qhov no yog ua tau vim kev noj ntawm ib qho me me ntawm carbohydrates. Yog tias cov ntshav qog ntshav tau pauv mus, ces nws yog qhov yuav tsum tau qhia rau koj tus kws kho mob txog qhov no.
Thaum lub sij hawm kho nrog Gensulin r, qhov teeb meem sib cais ntawm qhov txo qis lossis nce ntxiv ntawm cov rog yog ua tau. Cov txheej txheem zoo sib xws tau pom nyob ze ntawm qhov chaw txhaj tshuaj. Nws muaj peev xwm kom tsis txhob muaj qhov tshwm sim no los ntawm kev hloov chaw tas li txhaj tshuaj.
Yog tias cov tshuaj insulin siv thaum cev xeeb tub, nws yog ib qho tseem ceeb uas yuav tau txiav txim siab tias hauv thawj peb lub hlis qhov xav tau rau ib yam tshuaj poob qis, thiab nyob rau zaum ob thiab thib peb nws nce siab heev. Thaum yug menyuam thiab tam sim ntawd tom qab, tej zaum yuav muaj qhov tsis txaus los ntawm lub cev xav tau cov tshuaj hormones.
Yog tias tus poj niam tab tom pub niam mis, tom qab ntawd qhov no nws yuav tsum tau nyob ze kev saib xyuas ntawm tus kws kho mob (txog thaum lub sijhawm uas tus mob yuav khov kho).
Cov neeg mob ntshav qab zib uas tau txais ntau tshaj 100 units ntawm Gensulin P thaum nruab hnub yuav tsum tau mus pw hauv tsev kho mob nrog kev hloov tshuaj.
Cov theem ntawm kev cuam tshuam nrog lwm cov tshuaj
Los ntawm cov kws tshuaj pom, cov tshuaj no tsis sib xws nrog lwm cov tshuaj.
Kev mob ntshav siab ntshav qab zib tuaj yeem tsim txom los ntawm:
- sulfonamides;
- MAO inhibitors;
- carbonic anhydrase inhibitors;
- ACE inhibitors, NSAIDs;
- anabolic tshuaj steroids;
- androgens;
- Li + npaj.
Qhov tshwm sim cuam tshuam rau lub xeev ntawm kev noj qab haus huv ntawm ntshav qab zib (txo qis ntshav qab zib) yuav muaj kev siv Gensulin nrog cov txhais tau tias:
- qhov ncauj tiv thaiv;
- voj diuretics;
- estrogens;
- tshuaj maj
- H1 histamine receptor blockers;
- nicotine;
- glucagon;
- somatotropin;
- epinephrine;
- clonidine;
- tricyclic cov tshuaj tiv thaiv kab mob;
- morphine.
Muaj cov tshuaj uas tuaj yeem cuam tshuam lub cev hauv ob txoj kev. Pentamidine, octreotide, reserpine, ntxiv rau beta-blockers tuaj yeem ob leeg txhim kho thiab ua kom cov nyhuv tsis muaj zog hypoglycemic ntawm cov tshuaj Gensulin r.
