Farmasulin yog ib qho khoom siv nrog cov ntsiab lus hypoglycemic. Cov tshuaj muaj cov tshuaj insulin - ib yam tshuaj uas ua rau cov metabolism hauv qabzib. Ntxiv nrog rau kev tswj cov metabolism, insulin cuam tshuam rau cov txheej txheem anti-catabolic thiab anabolic uas tshwm sim hauv cov ntaub so ntswg.
Cov tshuaj insulin txhim kho kev sib txuas ntawm glycerin, glycogen, cov roj ntsha thiab cov nqaijrog hauv cov leeg nqaij. Nws pab txhim kho kev nqus ntawm amino acids thiab txo catabolism, glycogenolysis, lipolysis, ketogenesis thiab neoglucogenesis ntawm amino acids thiab cov protein.
Farmasulin n yog ib qho yeeb tshuaj ceev uas muaj tib neeg cov tshuaj insulin, uas tau los ntawm DNA tshuaj lom neeg tshiab. Kev kho mob nyhuv tshwm sim 30 feeb tom qab kev siv tshuaj yeeb tshuaj, thiab lub sijhawm ntawm cov nyhuv yog 5-7 teev. Thiab qhov siab tshaj plaws ntshav plasma yog ua tiav tom qab 1 txog 3 teev tom qab kev coj ntawm cov tshuaj.
Tom qab siv cov tshuaj no, lub siab ntawm lub plasma concentration ntawm cov tshuaj nquag tshwm sim tom qab 2 txog 8 teev. Kev kho mob kom ua tiav tau 1 teev tom qab kev siv tshuaj yeeb, thiab lub sijhawm ntev tshaj plaws ntawm cov nyhuv yog 24 teev.
Thaum siv cov tshuaj farmasulin H 30/70, qhov kev kho mob tau ua tiav tom qab 30-60 feeb, thiab nws lub sijhawm ntev tshaj plaws yog 15 teev, txawm hais tias nyob hauv qee tus neeg mob cov nyhuv kho tsuas kav ib hnub. Lub ncov ntawm lub plasma concentration ntawm cov tshuaj nquag tau mus txog tom qab 1 txog 8,5 teev tom qab txhaj tshuaj.
Kev ntsuas rau siv
Farmasulin N yog siv los kho cov neeg mob ntshav qab zib mellitus thaum xav tau cov tshuaj insulin kom tswj tau cov ntshav qabzib. Cov tshuaj no feem ntau tau sau tseg rau kev kho mob thaum pib ntawm insulin-based diabetics thiab rau kev kho mob ntawm cov poj niam cev xeeb tub uas muaj kev mob ntshav qab zib.
Ua tib zoo mloog! Cov tshuaj N 30/70 thiab N NP raug tshuaj rau hom 1 thiab ntshav qab zib hom 2 nrog rau kev noj zaub mov tsis muaj txiaj ntsig thiab muaj kev cuam tshuam cov tshuaj hypoglycemic.
Cov hau kev thov qauv
Farmasulin n:
Cov tshuaj yog muab tshuaj subcutaneously thiab txhaj tshuaj. Ntxiv mus, nws tuaj yeem raug tswj hwm intramuscularly, tab sis thawj ob txoj kev yog siv ntau zaus. Qhov ntau thiab ntau npaum li cas ntawm kev tswj hwm yog txiav txim los ntawm tus kws kho mob, ua raws li cov kev xav tau ntawm txhua tus neeg mob.
Hauv qab daim tawv nqaij, cov yeeb yaj kiab yog txhaj rau hauv lub plab, pwg, pob tw los yog ncej puab. Tib lub sijhawm, kev txhaj tshuaj tsis tuaj yeem ua tas li rau hauv ib qho chaw (tsis ntau tshaj 1 zaug hauv 30 hnub). Qhov chaw uas txhaj tshuaj yuav tsum tsis txhob txhuam, thiab lub sijhawm txhaj nws yog qhov tsim nyog los xyuas kom meej tias cov tshuaj no tsis nkag mus rau hauv cov hlab.
Cov kua los rau kev txhaj tshuaj hauv daim cartridges yog siv nrog tus cwj mem tshwj xeeb uas sau "CE". Koj tuaj yeem siv cov tshuaj ntxuav kom huv xwb uas tsis muaj xim thiab tsis huv.
Yog tias muaj qhov xav tau ntawm kev qhia ntawm ntau cov insulin-cov neeg sawv cev hauv ib zaug, tom qab ntawd tus txheej txheem yog nqa tawm siv ntau koob txhaj tshuaj. Cartridge them cov txheej txheem tau piav qhia hauv cov lus qhia uas tuaj nrog tus xaum xaum qhuav.
Rau kev qhia txog cov tshuaj muaj nyob hauv cov vials, koob txhaj tshuaj siv, lawv qhov kev kawm tiav yuav tsum sib haum rau hom tshuaj insulin. Txhawm rau tswj hwm cov tshuaj N, nws raug nquahu kom siv cov tshuaj insulin ua haujlwm ntawm tib lub chaw tsim khoom thiab cov chaw tsim khoom, raws li kev siv lwm cov koob txhaj tshuaj yuav ua rau kom muab cov tshuaj tsis yog.
Koj tuaj yeem siv tsuas yog cov xim tsis muaj xim, cov tshuaj dawb huv uas tsis muaj qhov ua tsis zoo. Nws raug nquahu tias qhov ntsuas kub ntawm qhov muab tshuaj yog ua kom zoo nrog chav sov.
Tseem Ceeb! Kev txhaj tshuaj yuav tsum ua nyob rau hauv qhov xwm txheej tsis huv.
Txhawm rau ua ib qho kev txhaj tshuaj, nws yuav xub nqus cov cua mus rau hauv cov koob txhaj kom txog qib uas xav tau qhov kev daws teeb meem, thiab tom qab ntawd cov koob tso rau hauv lub vial thiab huab cua raug tso tawm. Tom qab lub raj mis yuav tsum tau tig mus rau sab hauv thiab sau cov kab yuav tsum tau ntawm cov tshuaj insulin. Yog tias nws tsim nyog los tswj cov ntau hom tshuaj insulin, ib rab koob sib cais thiab koob txhaj tshuaj siv rau txhua hom.
Farmasulin H 30/70 thiab Farmasulin H NP
Formalin H 30/70 yog kev sib xyaw ntawm kev daws teeb meem ntawm H NP thiab N. Cov cuab yeej tso cai rau koj nkag mus rau ntau hom tshuaj insulin yam tsis tau npaj tus kheej ntawm cov tshuaj insulin.
Txoj kev hais daws sib tov yog muab tshuaj subcutaneously, soj ntsuam txhua yam tsim nyog tshuaj aseptic. Qhov kev txhaj tshuaj yog tsim nyob hauv plab, xub pwg, ncej puab lossis pob tw. Hauv qhov no, qhov chaw txhaj tshuaj yuav tsum tau hloov tas li.
Tseem Ceeb! Saib xyuas yuav tsum tau ua kom ntseeg tau tias thaum txhaj tshuaj yuav daws tsis tau cov kab noj hniav ntawm lub cev.
Tsuas yog cov ntshiab, tsis muaj kob daws dawb los ntawm impurities thiab nag lossis daus tuaj yeem siv. Ua ntej siv lub raj mis, koj yuav tsum txhuam nws me ntsis hauv xib teg, tab sis koj tsis tuaj yeem co nws, vim yog ua npuas dej yog tsim, thiab qhov no yuav ua rau muaj teeb meem hauv kev nce qhov koob xav tau.
Nws raug nquahu kom siv cov koob txhaj tshuaj uas muaj qhov kawm tiav sib xws rau koob tshuaj insulin. Lub sijhawm nruab nrab ntawm kev qhia ntawm cov tshuaj thiab kev siv cov zaub mov yuav tsum tsis pub ntau tshaj 1 teev rau kev daws ntawm N NP thiab tsis pub ntau tshaj ib nrab teev rau txoj kev ntawm H 30/70.
Tseem Ceeb! Thaum siv, cov tshuaj yuav tsum ua raws li kev noj haus kom nruj.
Txhawm rau txhim kho qhov ntau npaum, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus lej ntawm glucosuria thiab glycemia rau 24 teev thiab saib xyuas glycemia qhov ntawm lub plab khoob.
Txhawm rau txhawm rau kev daws teeb meem rau hauv cov phwj, koj yuav tsum xub kos cov cua mus rau nws rau qhov cim uas txiav txim siab koob xav. Tom qab ntawd lub koob tau muab tso rau hauv lub vial, thiab huab cua tso tawm. Tom qab cov ampoule yog tig rov qab thiab qhov ntim ntawm cov kev daws tau sau.
Qhov kev ncua yuav tsum tau txhaj rau cov tawv nqaij ntawm cov ntiv tes, thiab rab koob yuav tsum muab ntxig ntawm kaum ntawm 45 degrees. Txhawm rau cov tshuaj insulin tsis tas, tom qab txhaj tshuaj tas, qhov chaw uas yuav tsum muaj cov cim koob yuav tsum nias me ntsis.
Ua tib zoo mloog! Hloov daim foos tso tawm, hom thiab tuam txhab ntawm insulin yuav tsum tau txais kev pom zoo nrog tus kws kho mob koom nrog.
Sab sij huam
Thaum siv tshuaj kho, qhov tshwm sim feem ntau yuav tshwm sim yog hypoglycemia. Cov mob no ua rau yus tsis nco qab thiab tuag taus.
Feem ntau hypoglycemia kev loj hlob vim yog:
- kev noj haus tsis txaus;
- insulin noj ntau dhau;
- kev tawm dag zog lub cev;
- haus cawv uas muaj cawv.
Txhawm rau kom zam dhau qhov xwm txheej phem, tus neeg mob ntshav qab zib yuav tsum ua raws li kev noj haus kom zoo thiab soj ntsuam cov tshuaj kom meej, raws li kws kho mob tau hais tseg.
Tsis tas li, nrog lub sijhawm ntev ntawm kev siv tshuaj yeeb tuaj yeem ua rau kev txhim kho ntawm:
- atrophy ntawm subcutaneous rog ntawm thaj chaw txhaj tshuaj;
- hypertrophy ntawm subcutaneous rog txheej nyob ntawm qhov chaw txhaj tshuaj;
- insulin tsis kam;
- kev ua haujlwm tsis txaus siab;
- kev tshuaj tiv thaiv kev ua haujlwm hauv daim ntawv ntawm hypotension;
- urticaria;
- bronchospasm;
- hyperhidrosis.
Yog tias muaj teeb meem, koj yuav tsum sab laj nrog tus kws kho mob tshwj xeeb, vim qee qhov yuav tshwm sim yuav tsum hloov cov tshuaj thiab kho kev kho mob rov kho dua.
Cov Yuav Tsum Muaj
Cov tshuaj yuav tsum tsis txhob raug txwv rau cov neeg mob uas ua rau lub siab tsis txaus ntawm cov tshuaj ntawm cov tshuaj. Tsis tas li, cov tshuaj tsis pom zoo rau siv nyob rau hauv qhov muaj cov qog ntshav qab zib.
Cov neeg muaj ntshav qab zib siab ntev, lub sijhawm ntev, cov neeg mob uas tau txais beta-blockers, thiab cov neeg mob ntshav qab zib yuav tsum siv ceev faj heev. Tom qab tag nrho, nyob rau hauv tus neeg uas nyob rau hauv ib ntawm cov xwm txheej no, cov tsos mob ntawm kev mob hypoglycemia tuaj yeem hloov lossis tsis hais tawm.
Nyob rau ntawm qhov muaj cov mob ua ke ntawm cov kab mob, nrog kev ua haujlwm tsis txaus ntawm cov qog adrenal, cov thyroid caj pas, pituitary caj pas thiab lub raum, nws yog qhov yuav tsum tau sab laj nrog tus kws kho mob txog kev noj tshuaj. Tom qab tag nrho, cov teeb meem no tuaj yeem ua rau qhov kev xav tau los hloov cov tshuaj insulin.
Hauv qee kis, kev siv cov farmasulin rau kev kho mob ntawm cov menyuam tshiab tau tso cai.
Ua tib zoo mloog! Thaum tsav tsheb thiab lwm cov txheej txheem thaum lub sijhawm kho mob nrog farmasulin, yuav tsum saib xyuas.
Cev xeeb tub thiab lactation
Cov poj niam cev xeeb tub tuaj yeem siv cov tshuaj farmasulin, tab sis cov koob tshuaj insulin yuav tsum tau xaiv kom raug raws li qhov ua tau. Tom qab tag nrho, nrog kev lactation thiab cev xeeb tub, qhov yuav tsum tau siv tshuaj insulin tuaj yeem hloov pauv.
Yog li, tus poj niam yuav tsum sab laj nrog kws kho mob ua ntej npaj, lub sijhawm thiab tom qab cev xeeb tub.
Ua tib zoo mloog! Thaum cev xeeb tub, koj yuav tsum tau saib xyuas tas li ntawm cov piam thaj hauv ntshav.
Yeeb tshuaj sib cuam tshuam
Cov kev kho mob nyhuv yuav tsawg dua yog tias noj cov tshuaj farmasulin nrog rau:
- tshuaj noj tswj kev xeeb tub;
- cov thyroid tshuaj;
- hydantoin;
- qhov ncauj tiv thaiv;
- tshuaj kho mob;
- glucocorticosteroid tshuaj;
- heparin;
- lithium npaj;
- beta 2 -adrenoreceptor agonists.
Kev xav tau Insulin yog txo qis thaum muaj kev sib xyaw ntawm kev siv farmasulin nrog:
- antidiabetic peroral tshuaj;
- ethyl cawv;
- phenylbutazone;
- cov muaj ntsev;
- cyclophosphamide;
- monoamine oxidase inhibitors;
- anabolic tshuaj steroids;
- cov kab mob sulfonamide;
- strophanthin K;
- angiotensin enzyme inhibitors;
- clofibrate;
- beta adrenergic receptor blockers;
- tetracycline;
- octreotide.
Noj ntau dhau
Kev noj tshuaj ntau dua cov neeg ua liaj ua teb tuaj yeem ua rau cov ntshav nce zuj zus. Kev noj ntau dhau kuj ua rau muaj kev cuam tshuam yog tias tus neeg mob tsis noj zaub mov zoo lossis ua kom lub cev ntau dhau nrog cov kev ua kis las. Ntxiv mus, insulin thov yuav poob qis, yog li ib qho kev txhaj tshuaj ntau dhau txawm hais tias tom qab thov kev noj tshuaj insulin ib txwm muaj.
Tsis tas li, yog tias muaj ntau dhau ntawm cov tshuaj insulin, hyperhidrosis, tshee qee zaus tshwm sim, lossis txawm tsaus muag. Tsis tas li ntawd, cov piam thaj hauv qhov ncauj (cov dej qab zib) yog qhov sib kis ntawm cov teeb meem no.
Yog tias muaj mob ntau dhau, 40% piam thaj lossis 1 mg glucogan yog txhaj rau cov tshuaj. Yog tias qhov kev kho mob zoo li no tsis pab, ces glucocorticosteroids lossis mannitol raug muab rau tus neeg mob kom tiv thaiv tus mob txha caj qaum.
Daim ntawv tso tawm
Pharmasulin npaj rau kev siv niam txiv muaj nyob hauv:
- hauv ntim ua los ntawm cov duab los qhia (1 lub raj mis nrog);
- hauv khob fwj (ntawm 5 txog 10 ml);
- nyob rau hauv ib pob ntawv ntawm cardboard (5 cartridges tso rau hauv lub thawv contour);
- hauv khob daim iav (3 ml).
Cov lus thiab cov xwm txheej ntawm kev cia
Pharmasulin yuav tsum muab khaws cia rau qhov siab tshaj 2 xyoos ntawm qhov kub ntawm 2 - 8 ° C. Tom qab cov pob tshuaj tau qhib, cov vials, daim cartridges lossis cov kev daws teeb meem yuav tsum tau muab cia rau hauv chav tsev tus qauv kub. Hauv qhov no, nws tsis tuaj yeem ua rau ncaj qha tshav ntuj kom poob rau ntawm cov tshuaj.
Tseem Ceeb! Tom qab pib siv, farmasulin tuaj yeem muab khaws cia tsis pub dhau 28 hnub.
Yog tias muaj cua daj cua dub lossis dej nag tshwm nyob rau hauv qhov kev ncua, tom qab ntawd qhov cuab yeej ntawd yog raug txwv.
