Langerin yog ib qho ntawm ntau cov tshuaj noj tshuaj uas yog siv los kho tus txheej txheem pathological hu ua non-insulin-dependant ntshav qab zib mellitus. Cov tshuaj yog ib feem ntawm cov lag luam biguanide ntawm cov tshuaj, cov kev cuam tshuam tseem ceeb ntawm kev ua kom txo qis qhov xav tau ntawm cov tshuaj insulin.
Tus nqi ntawm Langerin hauv cov khw muag tshuaj, nyob ntawm qhov yuav tsum tau ntau npaum li cas, tuaj yeem nyob ntawm ib puas txog peb puas rubles.
Langerin yog cov tshuaj noj hauv qhov ncauj uas yog siv rau hauv txoj kev kho mob ntshav qab zib. Nws lub ntsiab feem yog cov tshuaj metformin. Cov tshuaj yog ib cov tshuaj uas txo cov ntshav qab zib thiab feem ntau yog siv los ua kom cov ntshav qab zib nyob hauv ntshav qab zib muaj ntau dua.
Ib qho ntawm cov tshuaj tuaj yeem tau txais ntawm cov tshuaj no yog nws txoj kev tswj hwm nyob rau hauv kev tsis muaj txiaj ntsig ntawm cov ntsiav tshuaj uas tau siv yav dhau los los ntawm sulfonylurea pawg. Ib qho ntxiv, kev rog yog qhov teeb meem uas ua rau txhua tus neeg muaj ntshav qab zib.
Yog vim li ntawd, Langerin tso cai tsis tsuas yog ua kom cov suab thaj qis dua, tab sis kuj tseem ua rau lub cev qeeb dua qub ntawm tus neeg mob lub cev.
Tshuaj thaj tsob thiab cov cim rau kev siv
Lub tshuab nruab nrab ntawm kev ua ntawm qhov tseem ceeb ntawm cov tshuaj muaj feem xyuam nrog nws lub peev xwm los txwv cov txheej txheem ntawm gluconeogenesis, nrog rau cov txheej txheem ntawm kev ua ke ntawm cov roj ntsha dawb thiab cov roj oxidation. Tus sawv cev ntawm chav kawm biguanide tsis cuam tshuam rau qhov tshuaj insulin tso rau hauv cov ntshav, tab sis hloov nws cov chaw muag tshuaj los ntawm kev txo qis ntawm qhov khi ntawm cov insulin kom dawb thiab nce qhov feem ntawm cov insulin rau proinsulin.
Lub ntsiab lus tseem ceeb hauv cov txheej txheem ntawm kev nqis tes ntawm cov ntsiav tshuaj xws li yog qhov kev xav ntawm cov piam thaj kev qog los ntawm cov leeg hlwb.
Qhov tseem ceeb tshaj plaws rau kev siv tshuaj yog kev txhim kho ntawm cov tshuaj ntshav qab zib insulin nyob hauv ib tus neeg, tshwj xeeb tshaj yog nrog kev tsis muaj txiaj ntsig ntawm kev noj zaub mov ua raws.
Cov khoom tseem ceeb ntawm Langerin muaj xws li:
- txo cov ntshav glycated hemoglobinꓼ
- nruab nrab cov tshuaj insulin tsis ua haujlwm ntawm cov qe mus rau cov tshuaj insulinꓼ
- favorably cuam tshuam qhov normalization ntawm lipid profile ntawm cov ntshav ntshav ꓼ
- txo cov roj (cholesterol) phem
Txuas ntxiv, kev siv cov tshuaj muaj peev xwm ua kom lub cev qhov hnyav.
Cov lus qhia rau kev siv ntsiav tshuaj
Cov tshuaj Langerin yog muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj coated.
Cov ntawv ntim rau hauv lub hnab yas, uas tau ntim nrog txhuas ntawv ci.
Cov pob khoom tau muab tso rau hauv lub thawv ntawv thawv nrog cov lus qhia rau kev siv tshuaj.
Ua raws li qhov xav tau ntawm cov tshuaj tau siv, cov tshuaj tuaj yeem tuaj yeem yuav nrog ntau npaum li cas:
- 500 milligrams.
- 850 milligrams.
- Ib qho ntawm cov tshuaj muaj zog.
Cov qauv ntawm kev noj cov ntsiav tshuaj yog qhov ncauj, ntawm lub sijhawm noj mov lossis tom qab nws. Tus kws kho mob uas tuaj koom sau ntawv yuav muab ib qho tshuaj rau txhua tus neeg mob nyob ntawm seb tus kab mob loj npaum li cas. Tsis tas li, tus kws kho mob tshwj xeeb txiav txim qhov ntau npaum li cas ntawm cov tshuaj thaum nruab hnub.
Langerin-cov lus qhia rau kev siv pom zoo pib lub hom phiaj kho mob nrog kev noj tshuaj tsawg kawg yog 500 mg ntawm cov tshuaj nquag. Tus naj npawb ntawm cov koob tshuaj ntawm cov tshuaj nruab hnub yuav ua tau li ntawm ib mus txog peb. Maj mam, cov koob tshuaj tuaj yeem raug nce ntxiv rau 850 mg ntawm cov tshuaj nquag thoob plaws ib hnub (ib zaug ob zaug hauv ib hnub). Cov kws kho mob koom nrog saib xyuas qhov mob ntawm tus neeg mob thiab, tsis pub ntau tshaj ib zaug ib lim tiam, kho cov tshuaj ntawm cov tshuaj noj tau nce siab.
Cov tshuaj tseem ua tseem ceeb rau kev kho mob ntawm tus menyuam hauv cov menyuam hnub nyoog ntau dua kaum xyoo. Kev kho mob Monotherapy yuav tsum pib nrog kev noj tshuaj ntawm 500 mg ntawm cov tshuaj nquag ib zaug lossis ob zaug ib hnub. Tom qab qee lub sijhawm, maj mam nce ntxiv ntawm cov koob tshuaj tau tso cai, tab sis tsis pub ntau tshaj ob grams hauv ib hnub, muab faib ua ob lossis peb koob tshuaj.
Feem ntau, hloov pauv ntawm txoj kev noj ntau npaum li cas ntawm cov tshuaj tshwm sim tom qab kaum txog kaum tsib hnub raws li cov txiaj ntsig ntawm kev kuaj ntshav rau cov piam thaj.
Qee qhov xwm txheej, kev npaj ntsiav tshuaj yog ib feem ntawm kev sib txuas ua ke nrog kev siv tshuaj insulin.
Nws yuav tsum raug sau tseg tias kev tswj hwm ib txhij ntawm Langerin nrog insulin, sulfonylurea derivatives, acarbose, lossis ACE inhibitors tsub kom cov nyhuv ntshav qab zib tsawg ntawm cov tshuaj.
Muaj qee kis, tus kws kho mob mus koom yuav hloov qhov kev siv Langerin nrog cov ntsiav tshuaj ntawm cov sib xws. Niaj hnub no, muaj ntau ntau cov tshuaj noj, lub ntsiab tseem ceeb ua ke ntawm uas yog metformin.
Tus nqi ntawm cov tshuaj analog tuaj yeem sib txawv, nyob ntawm seb lub tuam txhab ntawm cov chaw muag tshuaj.
Dab tsi yog cov contraindications rau siv?
Cov tshuaj noj tsis raug cai lossis tsis ua raws li cov lus pom zoo ntawm tus kws kho mob tuaj yeem ua rau pom kev phiv tshuaj tsis zoo thaum noj cov tshuaj.
Ntxiv rau, muaj qee qhov xwm txheej hauv kev siv tshuaj yeeb tshuaj raws li metformin yog txwv tsis pub.
Cov lus qhia rau kev siv tshuaj qhia cov npe ntawm contraindications tseem ceeb.
Lub ntsiab tseem ceeb rau kev siv cov Langerin ntsiav tshuaj muaj xws li cov hauv qab no:
- kev ua rau mob siab lossis lub raum tsis ua haujlwm, lawv qhov tsis txaus
- cawv, suav nrog nyob rau hauv mob ntev formꓼ
- lub plawv lossis ua pa tsis ua haujlwm ꓼ
- mob myocardial infarctionꓼ
- kev mob nkeeg uas tsis yog mob ntshav qab zib coma lossis poj koob yawm txwvꓼ
- kev loj hlob ntawm tus mob ko taw mob ko taw syndromeꓼ
- nyob rau hauv ib puag ncig ntawm ib tug neeg intolerance mus rau metformin thiab kev loj hlob ntawm kev tsis haum rau lub componentꓼ
- muaj cov kis mob sib kis-
- yoo mov nrog cov ntshav qab zib lossis ua raws li kev noj haus uas nws noj txhua hnub tsis pub dhau ib txhiab kilocaloriesꓼ
- ua ntej thiab tom qab phaisꓼ
- nrog cov kev raug mob uas tsis ntev los noꓼ
- ua ntej thiab tom qab kev kuaj mob uas siv lub xov tooj cua isotropes ntawm iodineꓼ
- ketoacidosis thiab mob lactic acidosis.
Ib qho ntxiv, cov poj niam yuav tsum tsis txhob noj cov tshuaj thaum cev xeeb tub thiab lactation.
Qhov tshwm sim ntawm kev mob tshwm sim tuaj yeem tshwm sim nws tus kheej rau ntawm ib feem ntawm ntau yam plab hnyuv siab raum thiab cov kab ke ntawm tib neeg lub cev - lub plab zom mov, metabolism, kab mob plawv, kab mob ntawm daim tawv nqaij. Cov kev tshwm sim tsis zoo uas tshwm sim los ntawm kev noj tshuaj yog:
- Txhawb siab. Qee zaum xeev siab tshwm sim hauv ntshav qab zib hom 2. Xeev siab yuav hloov los ntuav.
- Kev mob plab mog.
- Cov tsos ntawm cov xim hlau sib xyaw hauv qhov ncauj kab noj hniav.
- Hematopoiesis thiab hemostasis.
- Megaloblastic anemia.
- Txo cov ntshav qab zib kom qis dua cov qib uas siv tau - hypoglycemia.
- Cov tsos ntawm tsis muaj zog hauv lub cev.
- Kev nkees nkees.
- Kev Ntshav.
- Kev ua pa ntawm lub siab.
- Cov tsos ntawm dermatitis lossis ua pob rau ntawm daim tawv nqaij.
Ceev faj yuav tsum tau noj thaum noj Langerin nrog lwm cov tshuaj. Kev siv ua ke nrog cov ntsiav tshuaj nrog cymeditine nce kev pheej hmoo ntawm cov kab mob lactic acidosis. Kev sib xyaw ntawm Langerin nrog lub voj diuretics tuaj yeem txhim kho tib lub txiaj ntsig. Hauv qhov no, ntxiv rau qhov ua rau muaj kev tawm tsam ntawm cov kab mob lactic acidosis, ib qho kev pom ntawm lub raum tsis ua haujlwm tuaj yeem pom.
Siv cov tshuaj, nws yog ib qho tsim nyog los saib xyuas kev ua haujlwm ntawm lub raum thiab txiav txim siab cov lactate hauv ntshav tsawg kawg ob zaug hauv ib xyoos.
Cov ntaub ntawv hais txog cov tshuaj siv los kho ntshav qab zib tau muab tso rau hauv cov yeeb yaj kiab hauv tsab xov xwm no.
