Txhais tau tias los ntawm pab pawg neeg biguanide tau siv ntev los kho tus mob ntshav qab zib hom 2. Txawm li cas los xij, cov tshuaj no muaj ntau cov kev mob tshwm sim. Puas yog qhov no txhais tau hais tias metformin yog qhov tsis zoo, vim tias nws yog nws leej twg yog tus tseem ceeb muaj nyob hauv kev sib xyaw ntawm cov tshuaj?
Niaj hnub no, cov khoom tshiab ntawm cov tshuaj no tau raug tshawb pom thiab nws txoj kev siv tau nthuav dav txaus, siv cov tshuaj tsis yog hauv kev kho mob ntshav qab zib nkaus xwb.
Cov tshuaj Metformin tau siv ntev los kho hom 2 mob ntshav qab zib mellitus nrog rau kev noj zaub mov noj los ntawm kws kho mob. Nws tso cai tsis tsuas yog ua kom cov ntshav qabzib hauv cov ntshav hauv lub cev, tab sis kuj pab txo qhov hnyav, uas yog qhov tshwj xeeb rau cov neeg muaj tus mob no.
Txog rau hnub no, lwm cov yam ntxwv ntawm cov tshuaj kuj tau pom. Nws tau pom tseeb hauv kev lag luam tias ib tus neeg tuaj yeem coj Metformin kom ua tiav cov hom phiaj hauv qab no:
- Nws tiv thaiv lub hlwb los ntawm kev laus, uas tso cai rau nws siv rau lub hom phiaj prophylactic tiv thaiv Alzheimer tus kab mob.
- Favorably cuam tshuam rau lub xeev ntawm cov hlab ntsha thiab cov hlab ntsha. Yog li, nrog kev pab ntawm Metformin, kev txhim kho vascular atherosclerosis, lub plawv tsis ua haujlwm, tawg, vascular calcification tuaj yeem tiv thaiv.
- Txo cov feem ntau ntawm qog nqaij hlav cancer.
- Ua rau muaj kev cuam tshuam kev txhim kho ntawm potency rau cov txiv neej, uas tau cuam tshuam los ntawm ntau yam kab mob senile.
- Nws neutralizes txoj kev txhim kho osteoporosis hauv ntshav qab zib. Tshwj xeeb feem ntau, cov poj niam muaj kev txom nyem los ntawm cov pob txha brittle tom qab lawm, vim muaj qhov tseem ceeb txo qis hauv cov tshuaj hormones - estrogen.
- Favorably cuam tshuam qhov kev ua tau ntawm cov thyroid caj pas.
- Nws muaj lub luag haujlwm tiv thaiv hauv kev hais txog kev ua pa.
Txawm hais tias qhov tseeb tias ib cov tshuaj muaj ntau yam zoo, nws tsis tuaj yeem hais tias nws noj qab nyob zoo thiab tuaj yeem kho ntau yam kab mob. Zoo ib yam li lwm cov khoom siv kho mob, Metformin tuaj yeem siv tsuas yog qhia los ntawm tus kws kho mob koom nrog, coj mus rau hauv tus account qhov tseem ua kom tshwm sim ntawm txhua qhov cuam tshuam thiab contraindications.
Pharmacological cov yam ntxwv ntawm cov tshuaj
Metformin yog qhov muab tshuaj rau loj loj hauv chav loj uas yog siv rau kev kho mob ntshav qab zib hom 2.
Cov tshuaj tseem ceeb ntawm cov tshuaj yog Metroformin hydrochloride, silicon dioxide, povidone, magnesium stearate, macrogol yog siv los ua cov sib txuam sib xyaw.
Cov tshuaj yog nquag siv los txo cov ntshav qab zib. Nyob rau tib lub sijhawm, qhov txo qis hauv qhov ntsuas tshwm sim tsis tsuas yog tom qab noj mov tseem ceeb, tab sis kuj tso cai rau koj kom qis dua qib pib. Lub ntsiab ua haujlwm tseem ceeb ntawm cov ntsiav tshuaj tso cai rau koj los tswj kev tsim tawm ntawm cov tshuaj insulin los ntawm tus txiav, uas zoo cuam tshuam rau lub cev thiab tsis ua rau kev txhim kho hypoglycemia. Ib qho ntxiv, ntawm qhov zoo tshwm sim suav nrog:
- nruab nrab ntawm hyperinsulinomy;
- ua rau kom poob phaus;
- txo txoj kev pheej hmoo ntawm kev tsim kab mob ntawm cov hlab plawv;
- favorably cuam tshuam lipid metabolism hauv lub cev;
- txo cov txheej txheem ntawm cov roj oxidation;
- txo qhov nce tsawg ntawm cov roj (cholesterol) phem;
- txo txoj kev pheej hmoo ntawm mob ntshav qab zib angiopathy;
- txo triglycerides.
Cov tshuaj yog noj ntawm qhov ncauj, tom qab uas tom qab ob rau peb teev nws cov haujlwm siab tshaj plaws pib tshwm. Kwv yees li 6 teev tom qab siv tshuaj, qhov ntshav plasma concentration ntawm metformin poob qis, txij li qhov nqus ntawm cov khoom xyaw nquag xaus.
Thaum tab tom kho nrog cov tshuaj no tom qab ob peb hnub, koj tuaj yeem saib nws qhov muaj tas mus li hauv cov ntshav me me.
Cov lus qhia rau kev siv tshuaj
Cov tshuaj Metformin muaj nyob rau hauv cov ntsiav tshuaj daim ntawv hauv ntau yam tshuaj. Cov tshuaj muaj peev xwm yuav tau nyob ntawm cov chaw muag tshuaj hauv nroog raws li hauv qab no:
- 500 mg ntawm yam muaj sia nyob hauv ib ntsiav tshuaj;
- 850 mg ntawm cov khoom xyaw dhia;
- 1000 mg ntawm metformin.
Nyob ntawm seb ntau npaum li cas, cov cai rau kev noj tshuaj yuav nyob ntawm seb. Nws yuav tsum raug sau tseg tias tsuas yog tus kws kho mob tuaj koom tuaj yeem pom zoo siv cov tshuaj no, suav nrog kev hloov chaw rau cov tshuaj uas tau siv yav dhau los. Ib chav ntawm kev kho yog raug kho nyob rau hauv cov tshuaj noj uas pib los ntawm cov duab hauv chaw kuaj mob dav dav thiab tus yam ntxwv ntawm tus neeg mob lub cev. Qhov taw qhia tseem ceeb uas koj yuav tsum tau them sai sai rau thaum xaiv cov koob tshuaj yog qib ntawm cov piam thaj hauv ntshav thiab qhov hnyav ntawm tus neeg mob.
Qhov txhaj tshuaj tsawg kawg nkaus thaum pib kho tus mob yog 500 mg ntawm cov tshuaj nrog kev muaj peev xwm tom qab nce ntxiv. Ntxiv mus, kev noj tshuaj ib zaug tshuaj kuj tseem tuaj yeem tsis dhau tus lej saum toj no. Rau kev ua siab ntev zoo dua ntawm cov tshuaj, nrog rau rooj plaub ntawm cov koob tshuaj tau tsim tsa ntau, cov naj npawb ntawm cov koob tshuaj tuaj yeem muab faib ua ob lossis peb zaug thaum nruab hnub. Yog li, nws yuav muaj peev xwm tiv thaiv kev txhim kho ntawm qhov tsis zoo. Kev siv tshuaj ntau tshaj plaws yuav tsum tsis pub tshaj 3000 mg ntawm cov tshuaj nquag.
Qee qhov xwm txheej, piv txwv li, kev noj tshuaj rau cov hom phiaj prophylactic, kev noj tshuaj yuav tsum raug txo los ntawm ob txog peb zaug.
Qhov siab tshaj plaws ntawm kev noj tshuaj yog ua tiav tom qab ob lub lim tiam ntawm kev kho mob.
Yog tias, rau qee qhov xwm txheej, tsis muaj tshuaj kho mob, tsis tas yuav them nyiaj rau nws los ntawm qhov ntxiv rau koob tshuaj ntxiv.
Thaum noj tshuaj, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus lej ib txwm muaj kev ua haujlwm ntawm cov khoom noj hauv lub cev thiab kev noj qab haus huv zoo.
Nws yuav tsum raug sau tseg tias nws muaj qhov pheej hmoo siab ntawm lactic acidosis.
Cov kev tsis zoo los ntawm kev noj tshuaj
Kev kho thiab kho nrog Metformin yuav tsum tshwm sim nyob rau hauv kev saib xyuas zoo. Nws tsis tuaj yeem lees txais cov tshuaj hauv koob tshuaj ntau dua li cov lus pom zoo ntawm tus kws kho mob, lossis hauv kev sib xyaw nrog lwm cov tshuaj uas xaiv los ntawm tus neeg mob.
Kev siv tsis yog ntawm Metformin tuaj yeem ua rau muaj kev phiv ntau heev, cov khoom tsis zoo ntawm cov tshuaj rau tib neeg lub cev yuav qhib.
Cov kev tshwm sim tsis zoo ntawm cov tshuaj suav nrog cov hauv qab no:
- teeb meem ntawm lub plab zom mov, uas tuaj yeem nrog tus mob flatulence, mob hauv plab lossis raws plab;
- qhov tsis zoo tom qab ntawm cov hlau hauv qhov ncauj yuav tshwm sim tom qab noj mov;
- xeev siab thiab ntuav
- tsis muaj qee pawg ntawm cov vitamins, tshwj xeeb tshaj yog B12, yog li ntawd, nws raug nquahu kom ntxiv cov tshuaj muaj cov tshuaj tshwj xeeb, uas tuaj yeem ua rau qib theem ntawm txhua yam tshuaj uas tsim nyog rau lub cev;
- kev ua kom tshwm sim ntawm kev tsis haum tshuaj rau ib los yog ntau cov tshuaj;
- cov tsos mob ntawm kev qog ntshav qab zib;
- kev loj hlob ntawm cov kab mob lactic acidosis;
- megaloblastic anemia nyob rau hauv cov ntshav qab zib mellitus.
Thiab txawm hais tias Metformin tau muaj nyob hauv pab pawg ntawm cov tshuaj muaj kev nyab xeeb, koj yuav tsum ua tib zoo nyeem txhua qhov ua tau tshwm sim tsis zoo. Cov yeeb tshuaj no tuaj yeem tsim kev phom sij yog tias koj tsis ua raws li cov cai tsim nyog rau nws kev tswj hwm.
Ib qho cuam tshuam ntau tshaj plaws los ntawm kev siv tshuaj yeeb tshuaj yog lactic acidosis. Tus mob no yog nrog cov tsos mob xws li nce ntxiv tsaug zog, mob nqaij, txo lub cev kub thiab ntshav siab, thiab ua pa nyuaj. Nrog kev txhim kho ntawm cov kev mob tshwm sim no, tus neeg mob yuav tsum tau mus pw hauv tsev kho mob sai.
Lactic acidosis yog ib qho kev mob tshwm sim uas tshwm sim muaj txiaj ntsig los ntawm kev siv ntau dhau ntawm cov tshuaj.
Muaj dab tsi raug txwv tsis pub noj tshuaj?
Cov tshuaj Metformin muaj cov npe tseem ceeb ntawm cov kev tsis sib haum rau nws siv.
Yog li, ua ntej pib txoj haujlwm kho, koj yuav tsum ua tib zoo nyeem cov lus qhia. Yog tias muaj qhov tshwm sim tsis zoo, koj yuav tsum hu rau koj tus kws kho mob thiab sib tham txog kev nqis tes ua ntxiv rau kev noj tshuaj.
Nws yog txwv tsis pub siv cov tshuaj nyob rau hauv qhov muaj qhov tseeb thiab kev mob hauv qab no:
- rau kev kho mob ntawm hom 1 mob ntshav qab zib mellitus, cov neeg mob insulin-tiv thaiv cov neeg mob;
- kev txhim kho ntawm ketoacidosis, coma lossis tus pog koob yawg koob ntawm hom ntshav qab zib;
- cov kab mob pathological hnyav hauv lub raum lossis nplooj siab, nrog rau nyob ntawm lawv qhov tsis txaus;
- qee cov kab mob ntawm cov pa ntawm qhov mob, nrog rau thaum muaj teeb meem ua pa;
- kab mob ntawm cov hlab plawv system, plawv nres lossis myocardial infarction;
- kev txhim kho ntawm tus kabmob los ntawm ntau yam kabmob;
- tsis ntev los no phais thiab raug mob;
- Hmo ua ntej thiab tom qab qee qhov kev kuaj mob, cov no suav nrog radiography lossis radioisotropic kuaj, vim tias tus neeg sawv cev sib piv nrog cov ntsiab lus iodine siv.
- lactic acidosis;
- intolerance los yog hypersensitivity rau ib los yog ntau cov tshuaj;
- nyob rau hauv muaj cov cev qhuav dej;
- haus cawv ntau dhau los yog kev haus cawv tsis tu ncua.
Cov poj niam cev xeeb tub thiab poj niam thaum cev xeeb tub yog txwv tsis pub noj cov tshuaj Metformin, vim tias muaj teeb meem ntau yam nrog kev loj hlob ntawm tus me nyuam hauv plab. Nrog kev kho mob sai sai, tus poj niam yuav tsum tsis txhob pub mis niam.
Ib qho ntxiv, cov menyuam yaus hnub nyoog qis dua kaum-tsib yog qhov pheej hmoo.
Cov tshuaj ntawm cov tshuaj Metformin
Cov neeg mob tshuaj xyuas pom tias muaj txiaj ntsig zoo uas Metformin kev kho mob coj. Nws cov nqi nruab nrab hauv thaj chaw ntawm Lavxias teb sab tuaj yeem yog los ntawm 170 txog 260 rubles.
Yog tias tsim nyog, tus kws kho mob tuaj koom tuaj yeem hloov nrog lwm cov khoom kho mob nrog cov muaj pes tsawg leeg lossis cov khoom zoo sib xws. Txog rau hnub tim, txoj kev ua lag luam pharmacological muaj cov yeeb tshuaj hauv qab no ntawm cov tshuaj Metformin, uas, raws li kev txheeb xyuas, kuj muaj cov txiaj ntsig zoo:
- Glucophage - txo cov ntsiav tshuaj uas muaj nyob hauv ntau qhov ntau. Cov khoom siv tseem ceeb yog metformin hydrochloride. Yuav pab cov qib ntshav qabzib kom tsis muaj ntshav qab zib. Tus nqi qeb ntawm cov ntsiav tshuaj zoo li no, raws li txoj cai, tsis pub tshaj 200 rubles.
- Bagomet - ib cov tshuaj, nyob rau hauv cov muaj pes tsawg leeg uas muaj ob qho tshuaj nquag ib zaug - metformin thiab glibenclamide. Qhov no yog kev sib koom ua ke uas ua ke nrog cov khoom ntawm biguanides thiab sulfonylurea derivatives. Feem ntau siv los kho hom 2 mob ntshav qab zib mellitus. Tus nqi nruab nrab ntawm cov tshuaj yog 210-240 rubles.
- Siofor yog yeeb tshuaj los ntawm pab pawg biguanide, uas yog cov tshuaj tiav ua tiav ntawm Metformin ntsiav tshuaj. Nws tus nqi nruab nrab hauv cov khw muag tshuaj hauv nroog tuaj yeem sib txawv ntawm 250 txog 350 rubles.
- Sofamet - ntsiav tshuaj los ntawm chav kawm ntawm dimethylbiguanides, uas muaj nyob hauv ntau yam tshuaj. Nyob ntawm seb qhov tshuaj muaj pes tsawg, cov nqi tshuaj tau tsim los. Raws li txoj cai, tus nqi ntawm Sofamed nyob txawv chaw muag tshuaj ntawm lub nroog tsis tshaj 130 rubles;
- Nova Met.
Txog rau tam sim no, tus naj npawb ntawm analogues lossis cov lus txhais muaj ntau heev. Tag nrho ntawm lawv, raws li txoj cai, muaj cov khoom sib xws lossis zoo ib yam, tab sis txawv ntawm cov tuam txhab tsim khoom, nqe, npe. Ntxiv rau, cov kws kho mob pom zoo kom siv cov cuab yeej siv kho mob uas muaj, ntxiv rau cov kev ua haujlwm tseem ceeb, qhov tsawg kawg nkaus ntawm cov khoom siv pabcuam.
Cov ntaub ntawv ntawm Metformin yog muab hauv video hauv kab lus no.
