CardiASK yog ib qho tshuaj tiv thaiv ib-tshuaj. Nws ua ntau txoj haujlwm ib zaug: nws txo qhov kev hnyav ntawm qhov mob, inhibits cov txheej txheem ntawm gluing platelets, ntshav liab. Vim tias qhov no, tsis tsuas yog cov xwm txheej dav dav tuaj txhim kho, tab sis qhov kev pheej hmoo ntawm kev tsim muaj tus mob venous thrombosis kuj tseem tsawg dua. Cov tshuaj yeeb tshuaj yog qhov tawm tsam me ntsis ntawm cov qog ua kua rau lub plab zom mov dua li feem ntau cov tshuaj tiv thaiv ntawm NSAID pawg. Qhov no yog vim muaj ib daim nyias nyias tshwj xeeb npog cov ntsiav tshuaj.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Acetylsalicylic acid (hauv Latin - Acetylsalicylic acid).
CardiASK yog ib qho tshuaj tiv thaiv ib-tshuaj.
ATX
B01AC06 Acetylsalicylic acid
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yuav tau muas hauv cov ntawv hauv ncoo xwb. Cov pob muaj 30 lossis 60 pcs. Acetylsalicylic acid yog siv los ua cov tshuaj nquag. Nws qhov siab hauv 1 ntsiav tshuaj yog 50 mg. Nws muaj peev xwm yuav ib cov tshuaj nrog qhov ntau npaum ntawm qhov tseem ceeb cov tshuaj 100 mg. Cov tshuaj yog ib qho-tivthaiv, lwm cov kev sib txuas hauv cov khoom muaj pes tsawg leeg tsis qhia ua lub ntsej muag tiv thaiv kev tiv thaiv thiab tiv thaiv kab mob:
- stearic acid;
- pob kws nplej siab;
- lactose monohydrate (mis nyuj qab zib);
- cov roj castor hydrogenated;
- povidone;
- polysorbate;
- microcrystalline cellulose.
Cov tshuaj yuav tau muas hauv cov ntawv hauv ncoo xwb.
Pharmacological kev txiav txim
Cov tshuaj yog cim rau cov yam ntxwv xws li: anti-inflammatory, antipyretic, analgesic, antiplatelet. Qhov poob hauv lub cev kub vim yog cuam tshuam rau ntawm qhov chaw ntawm thermoregulation ntawm tus kab mob hypothalamus. Kev siv ntawm kev mob txo qis vim muaj peev xwm ntawm salicylates (derivatives ntawm ASA) ua rau muaj kev cuam tshuam rau aldogenic kev ua haujlwm ntawm bradykinin. Tsis tas li ntawd, cov tshuaj no cuam tshuam cov chaw zov me nyuam ntawm qhov mob rhiab.
Cov tshuaj hauv cov lus nug cuam tshuam txog kev tsim khoom ntawm prostaglandins, inhibits qhov tsim ntawm adenazine triphosphate. Nyob rau tib lub sijhawm, qhov kev txo qis hauv qib ntawm kev ua haujlwm ntawm hyaluronidase raug sau tseg, kev permeability ntawm capillaries txo. Lub hauv paus ntsiab lus ntawm kev txiav txim rau NSAIDs yog tib yam: ib qho txheej txheem tsis kam hloov pauv ntawm kev ua ub no ntawm cyclooxygenase isoenzymes kev loj hlob. Tsis zoo li lwm cov analogues, tus neeg sawv cev raws ASA xaiv rau COX-1.
Nyob rau tib lub sijhawm, permeability ntawm capillaries txo.
Cyclooxygenase-1 enzymes muab kev tswj hwm rau kev tsim cov prostaglandins uas yog lub luag haujlwm rau kev ncaj ncees ntawm txoj hnyuv plab, kev saib xyuas ntawm cov haujlwm platelet, thiab cov ntshav khiav ua haujlwm li qub. Lub luag haujlwm tseem ceeb ntawm CardiASK yog los cuam tshuam cov kev ua haujlwm ntawm cov enzymes, uas ua rau ntau qhov kev tsis sib haum xeeb hauv kev ua haujlwm ntawm cov kabmob thiab cov tshuab, piv txwv li, kom txo qis ntawm kev siv ntawm platelet sib sau ua ke, ntxiv rau, lawv cov nplaum rau cov phab ntsa ntawm cov hlab ntsha poob qis, zoo li muaj peev xwm ua raws lwm. Qhov tshwm sim yog cov nyhuv antiplatelet.
Nyob rau tib lub sijhawm, muaj qhov tsis zoo ntawm lub plab yog sau tseg. Txo cov nyhuv no kom tsawg, cov ntsiav tshuaj tau lo nrog cov txheej ntxeem ntxig, vim tias cov tshuaj ua kom tso tawm ntau qeeb dua, cov txheej txheem no pib txhim kho hauv txoj hnyuv. Raws li qhov tshwm sim, lub plab hnyuv tso tawm tsis ua rau muaj kev puas tsuaj rau cov tshuaj acetylsalicylic acid, kev siv ntau ntawm cov kev mob tshwm sim poob qis.
Cov Tshuaj Pharmacokinetics
Kev tso tawm ntawm cov tshuaj nquag tshwm sim hauv cov hnyuv. Peak siv tshuaj ua kom tiav hauv 3 teev. Cov txheej txheem ntawm kev hloov pauv ntawm acetylsalicylic acid tshwm sim hauv daim siab. Ntxiv mus, cov tshuaj no tsuas yog ib feem ntawm metabolized. Raws li qhov tshwm sim, cov tebchaw tsis tshua muaj siab tau tsim.
Cov txheej txheem ntawm kev hloov pauv ntawm acetylsalicylic acid tshwm sim hauv daim siab.
Ib nrab-lub neej yog luv - 15 feeb. Lub raum ua lub luag haujlwm rau txoj kev ua no. Ntxiv mus, nws tau sau tseg tias cov metabolites ntawm cov tshuaj nquag tawm hauv lub cev ntau qeeb, hauv 3 teev. Cov nyhuv antiplatelet yog muab tam sim ntawd, txawm tias tom qab noj me me ntawm acetylsalicylic acid. Nws mob tsawv rau 1 lub lim tiam.
Dab tsi pab
Cov ntsiab lus rau kev teem caij ntawm cov nyiaj hauv nqe lus nug:
- tiv thaiv kev txhim kho ntawm myocardial infarction, yog tias muaj tej yam tsis zoo ua rau pom qhov tshwm sim ntawm txoj kab mob no, piv txwv li, ntshav qab zib mellitus, kub siab, cov neeg laus laus, rog dhau, thiab lwm yam;
- kev tiv thaiv ntawm rov qab myocardial infarction;
- tiv thaiv kev txhim kho ischemic stroke;
- cerebrovascular kev sib tsoo;
- angina pectoris;
- kev tiv thaiv ntawm kev txhaws ntawm cov hlab ntshav los ntawm kev mob ntshav siab, qhov ntxim nyiam ntawm qhov no nce ntxiv thaum phais mob, nrog rau kev ua kom tsis txhob mob tsawg, kev cuam tshuam kev phais: kev mob ntshav ntawm cov leeg ntshav thiab cov hlab ntsha o hla kev sib tsoo, endarterectomy thiab angioplasty ntawm carotid hlab ntsha;
- kev tiv thaiv ntawm kev txhim kho ntawm cov kab mob nrog rau vascular kev cuam tshuam: venous thrombosis, pulmonary embolism, thiab lwm yam.
Cov ntsiab lus rau kev teem caij cov tshuaj hauv nqe lus nug - venous thrombosis.
Cov Yuav Tsum Muaj
Ib tug xov tooj ntawm pathological tej yam kev mob tau sau tseg nyob rau hauv uas nws yog txwv tsis pub siv tus neeg saib xyuas hauv nqe lus nug:
- ib tug neeg cov tshuaj tiv thaiv tsis zoo thaum kho nrog acetylsalicylic acid, thiab lwm yam tshuaj ntawm NSAID pawg muaj lwm cov tshuaj uas muaj nyob hauv;
- yaig txhim kho hauv cov nqaij mos ntawm lub plab lossis txoj hnyuv;
- los ntshav hauv cov hnyuv;
- ua txhaum ntawm txoj haujlwm ntawm lub tshuab ua pa hauv bronchial hawb pob, uas tsim nrog salicylates;
- Fernand-Vidal triad, nrog rau qhov pib zoo ib yam ntawm cov tsos mob ntawm ASK intolerance, hawb pob thiab mob siab polyposis;
- diathesis, nyob rau hauv uas muaj cov ntshav tso tawm dhau ntawm cov phab ntsa ntawm cov hlab ntsha, hauv qhov no, muaj qhov hloov pauv ntawm cov xim ntawm lub cev sab nraud.
Nrog saib xyuas
Qhov kev txwv txiav pawg no suav nrog kev txheeb ze sib piv:
- keeb kwm kev los ntshav thiab txoj kev yaig los ntawm txoj hnyuv huam tuaj;
- mob gout
- hyperuricemia
- bronchial hawb pob, tsis cuam tshuam nrog kev cuam tshuam nrog salicylates, thiab lwm yam kab mob ua pa;
- quav nyab kub;
- tsis muaj peev xwm ntawm cov vitamin K thiab piam thaj-6-phosphate dehydrogenase;
- sinus polyposis;
- kev tsis haum tshuaj rau ib qho yeeb tshuaj;
- ib txhij siv nrog metatrexate hauv kev noj tshuaj uas tsis pub tshaj 15 mg rau ib lim tiam.
Cov pab pawg ntawm cov kev txwv muaj suav nrog tus txheeb ze sib kis rau kev tsis haum tshuaj rau ib qho yeeb tshuaj.
Yuav noj li cas CardiASK
Cov ntsiav tshuaj yuav tsum tau noj nrog dej, tsis tas yuav zom, vim tias sib tsoo cov tshuaj ua ntej lub sijhawm (kom txog rau thaum nws nkag mus rau hauv cov hnyuv) hawv yuav muaj teeb meem loj. Noj mov tsis cuam tshuam rau qhov ua tau zoo ntawm tshuaj thiab nws cov metabolism. Yuav kho cov kab mob sib xws rau ntau yam kab mob:
- txhawm rau tiv thaiv myocardial infarction thiab tej yam kev mob uas muaj kev pheej hmoo ntawm kev tsim muaj tus mob thrombosis lossis thromboembolism: 0.05-0.2 g ib hnub, nws lees txais los siv cov tshuaj txhua hnub, nyob rau hauv rooj plaub no tus nqi ntawm ASA nce rau 0.3 g ib hnub, thawj cov ntsiav tshuaj yog zom, uas yuav nres sai sai rau cov tsos mob ntawm tus kab mob pathological;
- nyob rau hauv qhov muaj qhov tsis zoo ua rau muaj kev txhim kho myocardial infarction, taw rau 0.05-0.1 g ib hnub, nyob rau hauv rooj plaub uas cov tshuaj noj txhua txhua hnub, cov tshuaj ntau dua rau 0.3 g;
- kev tiv thaiv lwm yam mob (rov ua dua myocardial infarction, angina pectoris, thiab lwm yam): 0.05-0.3 g ib hnub.
Qhov ntau npaum li cas, nrog rau lub sijhawm kho mob, yog txiav txim siab coj mus rau hauv tus account lub hnub nyoog ntawm tus neeg mob, muaj lwm cov kabmob thiab qhov mob ntawm lub cev.
Cov ntsiav tshuaj yuav tsum tau noj nrog dej, tsis tas yuav zom.
Noj cov tshuaj rau ntshav qab zib
Nws raug tso cai siv tus neeg sawv cev nug nrog qhov kev kuaj mob no, txawm li cas los xij, cov koob tshuaj tuaj yeem hais rov qab, yog tsim nyog
Kev phiv los ntawm CardiASK
Qhov tsis zoo ntawm cov tshuaj no yog qhov tshwm sim tsis zoo ntau uas tshwm sim thaum kho. Lawv tus lej thiab qhov tsis sib txawv, uas cuam tshuam los ntawm hom kab mob thiab tus neeg mob lub sijhawm.
Kev kho mob txoj hnyuv
Kev kub siab, ntuav tawm tsam xeev ntuav, mob tawm tsam ntawm lub plab ua kua ntawm lub plab zom mov, perforation (mob hnyav), mob hauv plab.
Cov Kev Mob Tshwm Sim CardiASK - mob hauv plab.
Hematopoietic plab hnyuv siab raum
GI los ntshav, ua ntshav khiav ceev.
Nruab nrab hauv lub paj hlwb
Mob taub hau thiab kiv taub hau, hnov lus tsis zoo.
Los ntawm lub tshuab ua pa
Bronchospasm.
Kev ua xua
Quincke's edema, tsos mob urticaria (khaus, tawm pob, tshem tawm ntawm daim tawv nqaij), rhinitis, o ntawm lub qhov ntswg, qhov tsis nco qab ceeb.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Tsis muaj kev txwv txawm li cas los xij, txawm li cas los xij, nws raug nquahu kom siv kev xyuam xim thaum tsav tsheb.
Nws yuav tsum tau siv kev xyuam xim thaum tsav tsheb.
Cov lus qhia tshwj xeeb
Yog tias cov koob tshuaj ntau dua tsis tu ncua, yuav muaj kev cuam tshuam ntau ntxiv hauv cov neeg mob ntshav qab zib, piv txwv li, hypoglycemia yuav loj tuaj.
Tshaj dhau qhov ntau ntawm cov tshuaj ua rau muaj kev pheej hmoo los ntshav.
Siv thaum cev xeeb tub thiab lactation
Thaum lub sij hawm lub sij hawm ntawm kev xeeb tub, nws yog txwv tsis pub sau ntawv rau cov tshuaj nyob rau hauv nqe lus nug hauv 1st thiab 3rd trimesters. Nyob rau theem pib ntawm cev xeeb tub, qhov kev pheej hmoo ntawm kev hloov pauv pathological hauv cov ntaub so ntswg ntawm cov menyuam hauv plab nce. Hauv lub hlis tsis ntev los no, muaj kev ua haujlwm tsis muaj zog.
Thaum pub niam mis, lawv kuj tsis siv cov tshuaj hauv nqe lus nug. Qhov no yog vim qhov tseeb tias cov khoom noj khoom haus metabolites nkag mus rau niam lub mis.
CardiASK lub sijhawm teem rau me nyuam
Tsis siv rau thaum yau.
Siv rau lub sijhawm qub
Tso cai muab tshuaj. Tus nqi txhua hnub ntawm ASA tsis hloov, tab sis yuav tsum ceev faj.
Nws raug tso cai tshaj tawm cov tshuaj hauv cov laus.
Daim ntawv thov rau lub raum khiav tsis zoo
Tsis siv rau qhov tsis zoo ntawm cov khoom no. Cov tshuaj yog tshuaj rau lub raum ua kom tsis zoo, hauv qhov no, kev tshem tawm lub raum yog tshuaj ntsuas thiab kev saib xyuas ntawm tus kws kho mob yog qhov yuav tsum tau ua. Tus nqi ntawm cov lus hais no yuav tsum tsis pub tshaj 30 ml / min.
Siv rau lub siab ua haujlwm tsis zoo
Nws tsis yog qhov tsim tawm rau qhov tsis ua haujlwm ntawm lub cev no. Cov tshuaj muaj peev xwm siv tau nrog kev hloov pauv me thiab mob nyhav hauv lub siab ua haujlwm.
Cardiask Tshem Tsis Txaus
Nrog rau kev qaug cawv hauv daim ntawv tsis muaj zog, hnov lus tsis zoo, xeev siab, ntuav, hloov pauv hauv kev nco qab, kiv taub hau tuaj yeem tshwm sim. Yog tias tus menyuam tau noj tshuaj, metabolic acidosis feem ntau tshwm sim. Kev kho mob hauv cov xwm txheej zoo li no yog txhawm rau tshem tawm qhov tshaj dhau ntawm cov tshuaj, uas ua tiav los ntawm kev txo qis ntawm cov tshuaj lossis nws qhov tshem tawm, noj cov pa roj carbon activated, ua kom dej-electrolyte sib npaug.
Nrog rau kev qaug cawv ua mob me, kev hnov lus tsis zoo yuav tshwm sim.
Cov tsos mob ntawm intoxication loj:
- nce hauv lub cev kub rau qhov muaj nuj nqis heev;
- ua tsis taus pa ua tsis taus pa;
- ua txhaum ntawm cov dej-electrolyte sib npaug;
- txo hauv siab, inhibition ntawm lub siab ua haujlwm;
- hyper- lossis hypoglycemia;
- lub plab zom mov;
- hnov lus tsis zoo;
- tshuaj lom encephalopathy.
Hauv cov xwm txheej zoo li no, yuav tsum tau pw hauv tsev kho mob ntawm tus neeg mob.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv tib lub sij hawm nrog ntau yam txhais tau tias, lawv cov txiaj ntsig yuav raug txhim kho lossis txwv:
- cov nyhuv ntawm methotrexate yog txhim kho;
- qhov kev siv ntawm kev txiav txim ntawm anticoagulants nce;
- muaj qhov nce ntxiv ntawm qhov tshwm sim ntawm thrombolytic, tshuaj antiplatelet;
- theem ntawm digoxin hauv cov ntshav nce ntxiv;
- cov nyhuv ntawm cov kab mob hypoglycemic yog kho kom zoo;
- cov kev ua ntawm cov tshuaj hauv cov tshuaj tiv thaiv uricosuric npaj txo qis;
- qhov zoo ntawm kev noj salicylates yog txo los ntawm kev cuam tshuam nrog corticosteroids.
Cawv tau zoo
Cov tshuaj hauv cov nqe lus nug thaum haus cawv muaj dej muaj txiaj ntsig ua rau pom qhov ua kom los ntshav, thaum nce ntxiv.
Cov tshuaj hauv nqe lus nug, thaum haus cov dej cawv uas muaj cawv, ua rau pom qhov tsis los ntshav.
Analogs
Cov kev kho mob zoo uas tuaj yeem pom zoo:
- Acetylsalicylic acid;
- Thromboass;
- Cardiomagnyl;
- Tshuaj aspirin;
- Tshuaj aspirin Cardio;
- Thrombopol, lwm yam.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kev yuav cov tshuaj, tsis tas yuav tshuaj los ntawm.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Muaj cov zoo li no.
CardiSC nqi
Tus nqi nruab nrab hauv Russia yog 70-90 rubles.
Cia rau cov neeg mob rau cov tshuaj
Qhov ntsuas kub nyob hauv chav yuav tsum tsis pub tshaj + 25 ° C.
Hnub tas sij hawm
Kev cia siab siv lub sijhawm ntev ntawm cov tshuaj txij li hnub tso tawm yog 2 xyoos.
Chaw tsim tshuaj paus
Canonfarm Ntau Lawm, Russia.
Xyuas txog Cardiask
Valeria Vasilievna, 55 xyoo, Samara
Kuv nyiam yam tshuaj no, vim nws yooj yim los noj. Cov ntsiav tshuaj tsis tas yuav tsum sib faib, zoo ib yam li Aspirin. Yog lawm, thiab tus nqi zoo.
Veronika, 33 xyoo, Omsk
Kuv muaj cov kev mob tshwm sim thaum noj CardiASK: nws ua suab nrov hauv kuv lub pob ntseg, kuv zoo li kiv taub hau. Tus kws kho mob tau sau ntawv muab tshuaj rau noj - noj tshuaj txhua lwm hnub. Tab sis kuv yuav tsum tau txo qis dua vim tias muaj qhov tshwm sim tsis zoo.
